{"id":"https://openalex.org/W2886081133","doi":"https://doi.org/10.1021/acs.orglett.8b02057","title":"Rh(III)-Catalyzed Synthesis of 2-Alkylbenzimidazoles from Imidamides and N-Hydroxycarbamates","display_name":"Rh(III)-Catalyzed Synthesis of 2-Alkylbenzimidazoles from Imidamides and N-Hydroxycarbamates","publication_year":2018,"publication_date":"2018-08-09","ids":{"openalex":"https://openalex.org/W2886081133","doi":"https://doi.org/10.1021/acs.orglett.8b02057","mag":"2886081133","pmid":"https://pubmed.ncbi.nlm.nih.gov/30091935"},"language":"en","primary_location":{"id":"doi:10.1021/acs.orglett.8b02057","doi":"https://doi.org/10.1021/acs.orglett.8b02057","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.orglett.8b02057","pdf_url":null,"source":{"id":"https://openalex.org/S201989124","display_name":"Organic Letters","issn_l":"1523-7052","issn":["1523-7052","1523-7060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107274476","display_name":"Yan-Lin Li","orcid":"https://orcid.org/0000-0002-7369-3253","observed_orcids":["https://orcid.org/0000-0002-7369-3253"]},"institutions":[{"id":"https://openalex.org/I119045251","display_name":"Huaqiao University","ror":"https://ror.org/03frdh605","country_code":"CN","type":"education","lineage":["https://openalex.org/I119045251"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanlin Li","raw_affiliation_strings":["Engineering Research Center of Molecular Medicine of Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engineering Research Center of Molecular Medicine of Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021, P. R. China","institution_ids":["https://openalex.org/I119045251"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091580079","display_name":"Chunqi Jia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I119045251","display_name":"Huaqiao University","ror":"https://ror.org/03frdh605","country_code":"CN","type":"education","lineage":["https://openalex.org/I119045251"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunqi Jia","raw_affiliation_strings":["Engineering Research Center of Molecular Medicine of Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engineering Research Center of Molecular Medicine of Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021, P. R. China","institution_ids":["https://openalex.org/I119045251"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101470438","display_name":"Huan Li","orcid":"https://orcid.org/0000-0002-8321-1692","observed_orcids":["https://orcid.org/0000-0002-8321-1692"]},"institutions":[{"id":"https://openalex.org/I119045251","display_name":"Huaqiao University","ror":"https://ror.org/03frdh605","country_code":"CN","type":"education","lineage":["https://openalex.org/I119045251"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huan Li","raw_affiliation_strings":["Engineering Research Center of Molecular Medicine of Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engineering Research Center of Molecular Medicine of Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021, P. R. China","institution_ids":["https://openalex.org/I119045251"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Linhua Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I119045251","display_name":"Huaqiao University","ror":"https://ror.org/03frdh605","country_code":"CN","type":"education","lineage":["https://openalex.org/I119045251"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Linhua Xu","raw_affiliation_strings":["Engineering Research Center of Molecular Medicine of Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engineering Research Center of Molecular Medicine of Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021, P. R. China","institution_ids":["https://openalex.org/I119045251"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101523531","display_name":"Lianhui Wang","orcid":"https://orcid.org/0000-0002-9899-3148","observed_orcids":["https://orcid.org/0000-0002-9899-3148"]},"institutions":[{"id":"https://openalex.org/I119045251","display_name":"Huaqiao University","ror":"https://ror.org/03frdh605","country_code":"CN","type":"education","lineage":["https://openalex.org/I119045251"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lianhui Wang","raw_affiliation_strings":["Engineering Research Center of Molecular Medicine of Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engineering Research Center of Molecular Medicine of Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021, P. R. China","institution_ids":["https://openalex.org/I119045251"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029975178","display_name":"Xiuling Cui","orcid":"https://orcid.org/0000-0001-5759-766X","observed_orcids":["https://orcid.org/0000-0001-5759-766X"]},"institutions":[{"id":"https://openalex.org/I119045251","display_name":"Huaqiao University","ror":"https://ror.org/03frdh605","country_code":"CN","type":"education","lineage":["https://openalex.org/I119045251"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiuling Cui","raw_affiliation_strings":["Engineering Research Center of Molecular Medicine of Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021, P. R. China"],"raw_orcid":"https://orcid.org/0000-0001-5759-766X","affiliations":[{"raw_affiliation_string":"Engineering Research Center of Molecular Medicine of Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021, P. R. China","institution_ids":["https://openalex.org/I119045251"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5029975178"],"corresponding_institution_ids":["https://openalex.org/I119045251"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":2.0575,"has_fulltext":false,"cited_by_count":35,"citation_normalized_percentile":{"value":0.86677156,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"20","issue":"16","first_page":"4930","last_page":"4933"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11790","display_name":"N-Heterocyclic Carbenes in Organic and Inorganic Chemistry","score":0.296099990606308,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11790","display_name":"N-Heterocyclic Carbenes in Organic and Inorganic Chemistry","score":0.296099990606308,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10354","display_name":"Catalytic C\u2013H Functionalization Methods","score":0.179299995303154,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10871","display_name":"Catalytic Alkyne Reactions","score":0.07930000126361847,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/imidamide","display_name":"imidamide","score":0.7900000214576721},{"id":"https://openalex.org/keywords/rhodium-iii-catalysis","display_name":"rhodium(III) catalysis","score":0.9480000138282776},{"id":"https://openalex.org/keywords/cascade-reactions","display_name":"cascade reactions","score":0.8600000143051147},{"id":"https://openalex.org/keywords/regioselectivity","display_name":"regioselectivity","score":0.7839999794960022},{"id":"https://openalex.org/keywords/functional-group-tolerance","display_name":"functional group tolerance","score":0.7680000066757202},{"id":"https://openalex.org/keywords/benzimidazole-synthesis","display_name":"benzimidazole synthesis","score":0.7509999871253967}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.901047945022583},{"id":"https://openalex.org/C59759590","wikidata":"https://www.wikidata.org/wiki/Q2275927","display_name":"Regioselectivity","level":3,"score":0.8522738218307495},{"id":"https://openalex.org/C134121241","wikidata":"https://www.wikidata.org/wiki/Q899301","display_name":"Yield (engineering)","level":2,"score":0.7512252330780029},{"id":"https://openalex.org/C2777814067","wikidata":"https://www.wikidata.org/wiki/Q1752317","display_name":"Tandem","level":2,"score":0.7373674511909485},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.6838509440422058},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.6701579093933105},{"id":"https://openalex.org/C2777332933","wikidata":"https://www.wikidata.org/wiki/Q170409","display_name":"Functional group","level":3,"score":0.5668670535087585},{"id":"https://openalex.org/C2991944050","wikidata":"https://www.wikidata.org/wiki/Q36534","display_name":"Reaction conditions","level":3,"score":0.5588642954826355},{"id":"https://openalex.org/C535685238","wikidata":"https://www.wikidata.org/wiki/Q1153832","display_name":"Organic synthesis","level":3,"score":0.42588597536087036},{"id":"https://openalex.org/C58548122","wikidata":"https://www.wikidata.org/wiki/Q838390","display_name":"Cascade reaction","level":3,"score":0.4103180170059204},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.32344794273376465},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1021/acs.orglett.8b02057","doi":"https://doi.org/10.1021/acs.orglett.8b02057","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.orglett.8b02057","pdf_url":null,"source":{"id":"https://openalex.org/S201989124","display_name":"Organic Letters","issn_l":"1523-7052","issn":["1523-7052","1523-7060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic Letters","raw_type":"journal-article"},{"id":"pmid:30091935","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30091935","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic letters","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1133171332","display_name":null,"funder_award_id":"15PYY052SF01","funder_id":"https://openalex.org/F4320326296","funder_display_name":"Xiamen Southern Oceanographic Center"},{"id":"https://openalex.org/G2153628924","display_name":"\u65e0\u5916\u52a0\u6c27\u5316\u5242\u7684C-H\u952e\u5b98\u80fd\u56e2\u5316\u53cd\u5e94\u7814\u7a76","funder_award_id":"21572072","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2772853804","display_name":null,"funder_award_id":"21602064","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2812274483","display_name":null,"funder_award_id":"3502Z20150054","funder_id":"https://openalex.org/F4320311847","funder_display_name":"Xiamen Municipal Bureau of Science and Technology"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320311847","display_name":"Xiamen Municipal Bureau of Science and Technology","ror":"https://ror.org/006mtxa58"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320326296","display_name":"Xiamen Southern Oceanographic Center","ror":"https://ror.org/05q39k474"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":69,"referenced_works":["https://openalex.org/W280137907","https://openalex.org/W1503913853","https://openalex.org/W1902427796","https://openalex.org/W1949559959","https://openalex.org/W1964658576","https://openalex.org/W1967254706","https://openalex.org/W1971288902","https://openalex.org/W1978848753","https://openalex.org/W1983974652","https://openalex.org/W1992654553","https://openalex.org/W1992842386","https://openalex.org/W2003754630","https://openalex.org/W2012314528","https://openalex.org/W2017847164","https://openalex.org/W2026159532","https://openalex.org/W2029312499","https://openalex.org/W2031659413","https://openalex.org/W2032385683","https://openalex.org/W2061142370","https://openalex.org/W2063913713","https://openalex.org/W2064978647","https://openalex.org/W2067433167","https://openalex.org/W2072891692","https://openalex.org/W2080183992","https://openalex.org/W2083083566","https://openalex.org/W2092638601","https://openalex.org/W2094844841","https://openalex.org/W2104093225","https://openalex.org/W2118360399","https://openalex.org/W2118740852","https://openalex.org/W2123867758","https://openalex.org/W2124265447","https://openalex.org/W2125014016","https://openalex.org/W2127341692","https://openalex.org/W2131670056","https://openalex.org/W2133275647","https://openalex.org/W2144168852","https://openalex.org/W2145795138","https://openalex.org/W2146467179","https://openalex.org/W2150639224","https://openalex.org/W2151864089","https://openalex.org/W2154712803","https://openalex.org/W2156032117","https://openalex.org/W2216113537","https://openalex.org/W2218266460","https://openalex.org/W2276575606","https://openalex.org/W2307160623","https://openalex.org/W2308283129","https://openalex.org/W2314819290","https://openalex.org/W2317020669","https://openalex.org/W2322705312","https://openalex.org/W2335579226","https://openalex.org/W2335703390","https://openalex.org/W2338299216","https://openalex.org/W2415862763","https://openalex.org/W2515495840","https://openalex.org/W2522089613","https://openalex.org/W2569012662","https://openalex.org/W2607168506","https://openalex.org/W2621344781","https://openalex.org/W2743639497","https://openalex.org/W2747607000","https://openalex.org/W2748846788","https://openalex.org/W2798777617","https://openalex.org/W2950082485","https://openalex.org/W2951927646","https://openalex.org/W2953079162","https://openalex.org/W4230221156","https://openalex.org/W4252152472"],"related_works":["https://openalex.org/W4327737544","https://openalex.org/W7140293482","https://openalex.org/W2922844782","https://openalex.org/W2062707326","https://openalex.org/W2950436802","https://openalex.org/W2900454864","https://openalex.org/W2952565775","https://openalex.org/W2951313626","https://openalex.org/W4415436285","https://openalex.org/W2899603141"],"abstract_inverted_index":{"An":[0],"efficient":[1],"tandem":[2],"reaction":[3,60],"of":[4,34,55],"imidamides":[5],"and":[6,44,58],"N-hydroxycarbamates":[7],"has":[8],"been":[9],"developed.":[10],"Valuable":[11],"2-alkylbenzimidazoles":[12],"could":[13],"be":[14],"easily":[15],"obtained":[16],"in":[17,41],"up":[18],"to":[19],"97%":[20],"yield":[21],"for":[22],"more":[23],"than":[24],"20":[25],"examples.":[26],"The":[27],"products":[28],"would":[29],"further":[30],"streamline":[31],"the":[32],"synthesis":[33,43],"molecules,":[35],"which":[36],"are":[37],"essential":[38],"building":[39],"blocks":[40],"organic":[42],"drug":[45],"discovery.":[46],"This":[47],"protocol":[48],"features":[49],"high":[50],"regioselectivity,":[51],"efficiency,":[52],"good":[53],"tolerance":[54],"functional":[56],"groups,":[57],"mild":[59],"conditions.":[61]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":2}],"updated_date":"2026-10-26T11:51:55.731654","created_date":"2018-08-22T00:00:00"}