{"id":"https://openalex.org/W2885869674","doi":"https://doi.org/10.1016/j.mayocp.2017.12.028","title":"59-Year-Old Man With Fatigue, Weight Loss, and Hepatomegaly","display_name":"59-Year-Old Man With Fatigue, Weight Loss, and Hepatomegaly","publication_year":2018,"publication_date":"2018-08-10","ids":{"openalex":"https://openalex.org/W2885869674","doi":"https://doi.org/10.1016/j.mayocp.2017.12.028","mag":"2885869674","pmid":"https://pubmed.ncbi.nlm.nih.gov/30104045"},"language":"en","primary_location":{"id":"doi:10.1016/j.mayocp.2017.12.028","doi":"https://doi.org/10.1016/j.mayocp.2017.12.028","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.mayocp.2017.12.028","pdf_url":"http://www.mayoclinicproceedings.org/article/S0025619618302295/pdf","source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.mayoclinicproceedings.org/article/S0025619618302295/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005887623","display_name":"Jacob J. Orme","orcid":"https://orcid.org/0000-0002-0319-0239","observed_orcids":["https://orcid.org/0000-0002-0319-0239"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jacob J. Orme","raw_affiliation_strings":["Resident in Internal Medicine, Mayo Clinic School of Graduate Medical Education, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Resident in Internal Medicine, Mayo Clinic School of Graduate Medical Education, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017390274","display_name":"Surbhi Sidana","orcid":"https://orcid.org/0000-0003-3288-7614","observed_orcids":["https://orcid.org/0000-0003-3288-7614"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Surbhi Sidana","raw_affiliation_strings":["Resident in Hematology, Mayo Clinic School of Graduate Medical Education, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Resident in Hematology, Mayo Clinic School of Graduate Medical Education, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068637846","display_name":"Wilson I. Gonsalves","orcid":"https://orcid.org/0000-0001-6890-969X","observed_orcids":["https://orcid.org/0000-0001-6890-969X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Wilson I. Gonsalves","raw_affiliation_strings":["Advisor to residents and Consultant in Hematology, Mayo Clinic, Rochester, MN. Electronic address: gonsalves.wilson@mayo.edu","Advisor to residents and Consultant in Hematology, Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Advisor to residents and Consultant in Hematology, Mayo Clinic, Rochester, MN. Electronic address: gonsalves.wilson@mayo.edu","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Advisor to residents and Consultant in Hematology, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5068637846"],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":0.2455,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.66393822,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"93","issue":"10","first_page":"1525","last_page":"1529"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13533","display_name":"Medical Case Reports and Studies","score":0.7602999806404114,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13533","display_name":"Medical Case Reports and Studies","score":0.7602999806404114,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.04170000180602074,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.011500000022351742,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatomegaly","display_name":"hepatomegaly","score":0.8489999771118164},{"id":"https://openalex.org/keywords/weight-loss","display_name":"weight loss","score":0.8140000104904175},{"id":"https://openalex.org/keywords/fatigue","display_name":"fatigue","score":0.984000027179718},{"id":"https://openalex.org/keywords/early-satiety","display_name":"early satiety","score":0.8690000176429749},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.8920000195503235},{"id":"https://openalex.org/keywords/hyperlipidemia","display_name":"hyperlipidemia","score":0.8119999766349792},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.7239999771118164},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.4779999852180481},{"id":"https://openalex.org/keywords/carpal-tunnel-release","display_name":"carpal tunnel release","score":0.6779999732971191}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9719845652580261},{"id":"https://openalex.org/C544821477","wikidata":"https://www.wikidata.org/wiki/Q718113","display_name":"Weight loss","level":3,"score":0.6963337659835815},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.38980352878570557},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.30516424775123596},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.07246366143226624}],"mesh":[{"descriptor_ui":"D000069286","descriptor_name":"Bortezomib","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000075363","descriptor_name":"Immunoglobulin Light-chain Amyloidosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D000075363","descriptor_name":"Immunoglobulin Light-chain Amyloidosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000075363","descriptor_name":"Immunoglobulin Light-chain Amyloidosis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D000682","descriptor_name":"Amyloid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003520","descriptor_name":"Cyclophosphamide","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D003907","descriptor_name":"Dexamethasone","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D005221","descriptor_name":"Fatigue","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D005221","descriptor_name":"Fatigue","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006529","descriptor_name":"Hepatomegaly","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D006529","descriptor_name":"Hepatomegaly","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009202","descriptor_name":"Cardiomyopathies","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009202","descriptor_name":"Cardiomyopathies","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009202","descriptor_name":"Cardiomyopathies","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010534","descriptor_name":"Peritoneal Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D010534","descriptor_name":"Peritoneal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013163","descriptor_name":"Splenomegaly","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013163","descriptor_name":"Splenomegaly","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015431","descriptor_name":"Weight Loss","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020097","descriptor_name":"Natriuretic Peptide, Brain","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D061705","descriptor_name":"Image-Guided Biopsy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.mayocp.2017.12.028","doi":"https://doi.org/10.1016/j.mayocp.2017.12.028","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.mayocp.2017.12.028","pdf_url":"http://www.mayoclinicproceedings.org/article/S0025619618302295/pdf","source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},{"id":"pmid:30104045","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30104045","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic proceedings","raw_type":"Case Reports"}],"best_oa_location":{"id":"doi:10.1016/j.mayocp.2017.12.028","doi":"https://doi.org/10.1016/j.mayocp.2017.12.028","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.mayocp.2017.12.028","pdf_url":"http://www.mayoclinicproceedings.org/article/S0025619618302295/pdf","source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[{"id":"https://openalex.org/G1348871451","display_name":"Dysregulation of Glutamine Metabolism in the Pathogenesis of Multiple Myeloma","funder_award_id":"K23CA218742","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2885869674.pdf","grobid_xml":"https://content.openalex.org/works/W2885869674.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W1981541713","https://openalex.org/W2006454078","https://openalex.org/W2108020531","https://openalex.org/W2148197707","https://openalex.org/W2171033052","https://openalex.org/W2270408688","https://openalex.org/W2479222319","https://openalex.org/W2517949488","https://openalex.org/W2582134011","https://openalex.org/W2592799965","https://openalex.org/W2594655011","https://openalex.org/W2610799378","https://openalex.org/W6721425464"],"related_works":["https://openalex.org/W1973131109","https://openalex.org/W2559756480","https://openalex.org/W2041792999","https://openalex.org/W2019867305","https://openalex.org/W4297830247","https://openalex.org/W4283080437","https://openalex.org/W2092263182","https://openalex.org/W4413281565","https://openalex.org/W4232380247","https://openalex.org/W1965171624"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-08-22T00:00:00"}