{"id":"https://openalex.org/W2885581383","doi":"https://doi.org/10.1093/femsle/fny165","title":"On display: autotransporter secretion and application","display_name":"On display: autotransporter secretion and application","publication_year":2018,"publication_date":"2018-07-27","ids":{"openalex":"https://openalex.org/W2885581383","doi":"https://doi.org/10.1093/femsle/fny165","mag":"2885581383","pmid":"https://pubmed.ncbi.nlm.nih.gov/30085010"},"language":"en","primary_location":{"id":"doi:10.1093/femsle/fny165","doi":"https://doi.org/10.1093/femsle/fny165","is_oa":true,"landing_page_url":"https://doi.org/10.1093/femsle/fny165","pdf_url":"https://academic.oup.com/femsle/article-pdf/365/18/fny165/25552096/fny165.pdf","source":{"id":"https://openalex.org/S34954451","display_name":"FEMS Microbiology Letters","issn_l":"0378-1097","issn":["0378-1097","1574-6968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Letters","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/femsle/article-pdf/365/18/fny165/25552096/fny165.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009549165","display_name":"Peter van Ulsen","orcid":"https://orcid.org/0000-0002-2164-1611","observed_orcids":["https://orcid.org/0000-0002-2164-1611"]},"institutions":[{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Peter van Ulsen","raw_affiliation_strings":["Section Molecular Microbiology, Department of Molecular Cell Biology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit, 1081 HV Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section Molecular Microbiology, Department of Molecular Cell Biology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit, 1081 HV Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I865915315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025252476","display_name":"Katinka M Zinner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Katinka M Zinner","raw_affiliation_strings":["Section Molecular Microbiology, Department of Molecular Cell Biology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit, 1081 HV Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section Molecular Microbiology, Department of Molecular Cell Biology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit, 1081 HV Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I865915315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108028176","display_name":"Wouter S. P. Jong","orcid":"https://orcid.org/0000-0002-8907-6954","observed_orcids":["https://orcid.org/0000-0002-8907-6954"]},"institutions":[{"id":"https://openalex.org/I4210143424","display_name":"Abera Bioscience (Sweden)","ror":"https://ror.org/036yap806","country_code":"SE","type":"company","lineage":["https://openalex.org/I4210143424"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Wouter S P Jong","raw_affiliation_strings":["Abera Bioscience AB, SE-111 45 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Abera Bioscience AB, SE-111 45 Stockholm, Sweden","institution_ids":["https://openalex.org/I4210143424"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090879577","display_name":"Joen Luirink","orcid":"https://orcid.org/0000-0001-8431-0804","observed_orcids":["https://orcid.org/0000-0001-8431-0804"]},"institutions":[{"id":"https://openalex.org/I4210143424","display_name":"Abera Bioscience (Sweden)","ror":"https://ror.org/036yap806","country_code":"SE","type":"company","lineage":["https://openalex.org/I4210143424"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL","SE"],"is_corresponding":true,"raw_author_name":"Joen Luirink","raw_affiliation_strings":["Abera Bioscience AB, SE-111 45 Stockholm, Sweden","Section Molecular Microbiology, Department of Molecular Cell Biology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit, 1081 HV Amsterdam, The Netherlands"],"raw_orcid":"https://orcid.org/0000-0002-2164-1611","affiliations":[{"raw_affiliation_string":"Abera Bioscience AB, SE-111 45 Stockholm, Sweden","institution_ids":["https://openalex.org/I4210143424"]},{"raw_affiliation_string":"Section Molecular Microbiology, Department of Molecular Cell Biology, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit, 1081 HV Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I865915315"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5090879577"],"corresponding_institution_ids":["https://openalex.org/I4210143424","https://openalex.org/I865915315"],"apc_list":{"value":2500,"currency":"GBP","value_usd":3297},"apc_paid":null,"fwci":1.0954,"has_fulltext":true,"cited_by_count":60,"citation_normalized_percentile":{"value":0.75084746,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"365","issue":"18","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9785000085830688,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9785000085830688,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.008700000122189522,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.007499999832361937,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/autotransporters","display_name":"autotransporters","score":0.9850000143051147},{"id":"https://openalex.org/keywords/outer-membrane-secretion","display_name":"outer membrane secretion","score":0.5669999718666077},{"id":"https://openalex.org/keywords/bam-complex","display_name":"BAM complex","score":0.9909999966621399},{"id":"https://openalex.org/keywords/sec-translocon","display_name":"Sec translocon","score":0.9800000190734863},{"id":"https://openalex.org/keywords/gram-negative-bacteria","display_name":"Gram-negative bacteria","score":0.921999990940094},{"id":"https://openalex.org/keywords/outer-membrane-vesicles","display_name":"outer membrane vesicles","score":0.7089999914169312},{"id":"https://openalex.org/keywords/outer-membrane-vesicle-vaccine","display_name":"outer membrane vesicle vaccine","score":0.8569999933242798},{"id":"https://openalex.org/keywords/heterologous-protein-display","display_name":"heterologous protein display","score":0.8460000157356262},{"id":"https://openalex.org/keywords/cell-surface-display","display_name":"cell surface display","score":0.8489999771118164},{"id":"https://openalex.org/keywords/protein-secretion-mechanism","display_name":"protein secretion mechanism","score":0.6269999742507935},{"id":"https://openalex.org/keywords/virulence-factors","display_name":"virulence factors","score":0.7089999914169312}],"concepts":[{"id":"https://openalex.org/C146587185","wikidata":"https://www.wikidata.org/wiki/Q258248","display_name":"Bacterial outer membrane","level":4,"score":0.8731632232666016},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.8172717094421387},{"id":"https://openalex.org/C2780115692","wikidata":"https://www.wikidata.org/wiki/Q5747302","display_name":"Heterologous","level":3,"score":0.6889539957046509},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.614197850227356},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5794022679328918},{"id":"https://openalex.org/C199229279","wikidata":"https://www.wikidata.org/wiki/Q610647","display_name":"Translocon","level":4,"score":0.46058860421180725},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.434785395860672},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.4182947278022766},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.41176673769950867},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.267223060131073},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.23314577341079712},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.12922081351280212},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000069320","descriptor_name":"Type V Secretion Systems","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000072417","descriptor_name":"Protein Domains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006090","descriptor_name":"Gram-Negative Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035843","descriptor_name":"Biomedical Research","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":false},{"descriptor_ui":"D037521","descriptor_name":"Virulence Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D061505","descriptor_name":"Cell Surface Display Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/femsle/fny165","doi":"https://doi.org/10.1093/femsle/fny165","is_oa":true,"landing_page_url":"https://doi.org/10.1093/femsle/fny165","pdf_url":"https://academic.oup.com/femsle/article-pdf/365/18/fny165/25552096/fny165.pdf","source":{"id":"https://openalex.org/S34954451","display_name":"FEMS Microbiology Letters","issn_l":"0378-1097","issn":["0378-1097","1574-6968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Letters","raw_type":"journal-article"},{"id":"pmid:30085010","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30085010","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS microbiology letters","raw_type":"Journal Article"},{"id":"pmh:oai:research.vu.nl:openaire/92a2c89a-d9b8-474a-bb24-18667e2eddc0","doi":null,"is_oa":true,"landing_page_url":"https://research.vu.nl/en/publications/92a2c89a-d9b8-474a-bb24-18667e2eddc0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401107","display_name":"VU Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I865915315","host_organization_name":"Vrije Universiteit Amsterdam","host_organization_lineage":["https://openalex.org/I865915315"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Van Ulsen, P, Zinner, K M, Jong, W S P & Luirink, J 2018, 'On display: Autotransporter secretion and application', FEMS Microbiology Letters, vol. 365, no. 18, fny165, pp. 1-10. https://doi.org/10.1093/femsle/fny165","raw_type":"info:eu-repo/semantics/review"},{"id":"pmh:vu:oai:research.vu.nl:publications/92a2c89a-d9b8-474a-bb24-18667e2eddc0","doi":null,"is_oa":false,"landing_page_url":"https://research.vu.nl/en/publications/92a2c89a-d9b8-474a-bb24-18667e2eddc0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"FEMS Microbiology Letters, 365(18):fny165, 1 - 10. Wiley-Blackwell","raw_type":"info:eu-repo/semantics/other"}],"best_oa_location":{"id":"doi:10.1093/femsle/fny165","doi":"https://doi.org/10.1093/femsle/fny165","is_oa":true,"landing_page_url":"https://doi.org/10.1093/femsle/fny165","pdf_url":"https://academic.oup.com/femsle/article-pdf/365/18/fny165/25552096/fny165.pdf","source":{"id":"https://openalex.org/S34954451","display_name":"FEMS Microbiology Letters","issn_l":"0378-1097","issn":["0378-1097","1574-6968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Letters","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.46810001134872437,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2885581383.pdf","grobid_xml":"https://content.openalex.org/works/W2885581383.grobid-xml"},"referenced_works_count":111,"referenced_works":["https://openalex.org/W36310178","https://openalex.org/W220851782","https://openalex.org/W1503488066","https://openalex.org/W1507526689","https://openalex.org/W1532210870","https://openalex.org/W1701180156","https://openalex.org/W1742641792","https://openalex.org/W1885271015","https://openalex.org/W1904809137","https://openalex.org/W1967764488","https://openalex.org/W1971856033","https://openalex.org/W1975758800","https://openalex.org/W1976672416","https://openalex.org/W1980034554","https://openalex.org/W1982186232","https://openalex.org/W1985048571","https://openalex.org/W1988742847","https://openalex.org/W1990365720","https://openalex.org/W1991736406","https://openalex.org/W1993556314","https://openalex.org/W1993568444","https://openalex.org/W1995574274","https://openalex.org/W2003046928","https://openalex.org/W2006721213","https://openalex.org/W2009587256","https://openalex.org/W2018555025","https://openalex.org/W2024180691","https://openalex.org/W2026169768","https://openalex.org/W2029180535","https://openalex.org/W2032946869","https://openalex.org/W2036205039","https://openalex.org/W2036698204","https://openalex.org/W2038898103","https://openalex.org/W2039256713","https://openalex.org/W2039847066","https://openalex.org/W2044548799","https://openalex.org/W2045091361","https://openalex.org/W2046089352","https://openalex.org/W2048199055","https://openalex.org/W2051437715","https://openalex.org/W2051655976","https://openalex.org/W2053754839","https://openalex.org/W2058485193","https://openalex.org/W2060719766","https://openalex.org/W2060949222","https://openalex.org/W2072252061","https://openalex.org/W2073205282","https://openalex.org/W2081717721","https://openalex.org/W2085019401","https://openalex.org/W2087890383","https://openalex.org/W2089988505","https://openalex.org/W2095139984","https://openalex.org/W2097381450","https://openalex.org/W2099548197","https://openalex.org/W2102446456","https://openalex.org/W2104128981","https://openalex.org/W2105026925","https://openalex.org/W2105790696","https://openalex.org/W2107196196","https://openalex.org/W2109053795","https://openalex.org/W2110115561","https://openalex.org/W2112393035","https://openalex.org/W2113442468","https://openalex.org/W2114623459","https://openalex.org/W2116203390","https://openalex.org/W2116829083","https://openalex.org/W2123930272","https://openalex.org/W2128562787","https://openalex.org/W2133911454","https://openalex.org/W2135838357","https://openalex.org/W2139994008","https://openalex.org/W2140816237","https://openalex.org/W2141340493","https://openalex.org/W2141757789","https://openalex.org/W2148828623","https://openalex.org/W2149163736","https://openalex.org/W2149170211","https://openalex.org/W2149638691","https://openalex.org/W2151501755","https://openalex.org/W2152456015","https://openalex.org/W2154557623","https://openalex.org/W2166701832","https://openalex.org/W2170005333","https://openalex.org/W2218656852","https://openalex.org/W2235470599","https://openalex.org/W2266533396","https://openalex.org/W2275597726","https://openalex.org/W2282925852","https://openalex.org/W2356462242","https://openalex.org/W2400253296","https://openalex.org/W2407243616","https://openalex.org/W2513227928","https://openalex.org/W2520352983","https://openalex.org/W2525566551","https://openalex.org/W2528533631","https://openalex.org/W2548897357","https://openalex.org/W2588696975","https://openalex.org/W2615521039","https://openalex.org/W2735884833","https://openalex.org/W2740500210","https://openalex.org/W2750846815","https://openalex.org/W2758307621","https://openalex.org/W2761033614","https://openalex.org/W2767247526","https://openalex.org/W2768421721","https://openalex.org/W2781794800","https://openalex.org/W2783952753","https://openalex.org/W2785037501","https://openalex.org/W2790422100","https://openalex.org/W2793553348","https://openalex.org/W2794315993"],"related_works":["https://openalex.org/W1975758800","https://openalex.org/W1507526689","https://openalex.org/W2119490944","https://openalex.org/W2036698204","https://openalex.org/W2135838357","https://openalex.org/W3196610391","https://openalex.org/W2793553348","https://openalex.org/W2750846815","https://openalex.org/W2063476725","https://openalex.org/W2116203390"],"abstract_inverted_index":{"The":[0],"classical":[1],"monomeric":[2,28],"autotransporters":[3,57,124,162],"are":[4,25,164],"ubiquitously":[5],"used":[6],"by":[7,42,155],"Gram-negative":[8],"bacteria":[9],"to":[10,16,88,151,161],"export":[11],"virulence":[12],"and":[13,34,46,75,113,134],"colonization":[14],"factors":[15],"their":[17,22,59],"cell":[18,168],"surface":[19,106],"or":[20],"into":[21],"surroundings.":[23],"They":[24],"expressed":[26],"as":[27],"proteins":[29,110,158],"that":[30,163],"pass":[31],"the":[32,43,47,64,69,72,81,96,101,121,167],"inner":[33],"outer":[35,65,129],"membrane":[36,130],"in":[37,120,138],"two":[38],"consecutive":[39],"steps":[40],"facilitated":[41],"Sec":[44],"translocon":[45],"Bam":[48,73,86],"complex,":[49],"respectively.":[50],"In":[51],"this":[52],"mini-review":[53],"we":[54,145],"discuss":[55,76,135],"how":[56,77],"translocate":[58],"secreted":[60],"functional":[61],"domains":[62],"across":[63],"membrane.":[66],"We":[67,116],"highlight":[68],"interactions":[70],"with":[71,125],"complex":[74,141],"specific":[78],"features":[79],"of":[80,85,103,108,123,159],"recently":[82],"solved":[83],"structure":[84],"lead":[87],"a":[89,126],"mechanistic":[90],"model":[91],"for":[92,105,111],"autotransporter":[93,97],"secretion.":[94],"Furthermore,":[95],"secretion":[98,153],"pathway":[99],"is":[100],"system":[102],"choice":[104],"display":[107],"heterologous":[109,142,157],"biotechnical":[112],"biomedical":[114],"purposes.":[115],"summarize":[117],"recent":[118],"advances":[119],"application":[122],"focus":[127],"on":[128,166],"vesicle":[131],"vaccine":[132],"development":[133],"its":[136],"limitations":[137,154],"secreting":[139],"more":[140],"proteins.":[143],"Finally,":[144],"present":[146],"an":[147],"exciting":[148],"new":[149],"technology":[150],"circumvent":[152],"ligating":[156],"interest":[160],"displayed":[165],"surface.":[169]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":14},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-08-22T00:00:00"}