{"id":"https://openalex.org/W2885287752","doi":"https://doi.org/10.1038/s41374-018-0106-8","title":"PHF20L1 antagonizes SOX2 proteolysis triggered by the MLL1/WDR5 complexes","display_name":"PHF20L1 antagonizes SOX2 proteolysis triggered by the MLL1/WDR5 complexes","publication_year":2018,"publication_date":"2018-08-08","ids":{"openalex":"https://openalex.org/W2885287752","doi":"https://doi.org/10.1038/s41374-018-0106-8","mag":"2885287752","pmid":"https://pubmed.ncbi.nlm.nih.gov/30089852","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13024356"},"language":"en","primary_location":{"id":"doi:10.1038/s41374-018-0106-8","doi":"https://doi.org/10.1038/s41374-018-0106-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41374-018-0106-8","pdf_url":"https://www.nature.com/articles/s41374-018-0106-8.pdf","source":{"id":"https://openalex.org/S137146891","display_name":"Laboratory Investigation","issn_l":"0023-6837","issn":["0023-6837","1530-0307"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Laboratory Investigation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.nature.com/articles/s41374-018-0106-8.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100417872","display_name":"Qianqian Wang","orcid":"https://orcid.org/0000-0003-4919-1998","observed_orcids":["https://orcid.org/0000-0003-4919-1998"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qianqian Wang","raw_affiliation_strings":["State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China","State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, 518055, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, 518055, Shenzhen, China","institution_ids":["https://openalex.org/I20231570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100721745","display_name":"Min Yu","orcid":"https://orcid.org/0000-0001-7208-2197","observed_orcids":["https://orcid.org/0000-0001-7208-2197"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Yu","raw_affiliation_strings":["State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China","State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, 518055, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, 518055, Shenzhen, China","institution_ids":["https://openalex.org/I20231570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108058554","display_name":"Yue Ma","orcid":"https://orcid.org/0000-0003-1434-7374","observed_orcids":["https://orcid.org/0000-0003-1434-7374","https://orcid.org/0009-0002-9186-6901"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yue Ma","raw_affiliation_strings":["State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China","State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, 518055, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, 518055, Shenzhen, China","institution_ids":["https://openalex.org/I20231570"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiaoming Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoming Zhang","raw_affiliation_strings":["State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China","State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, 518055, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, 518055, Shenzhen, China","institution_ids":["https://openalex.org/I20231570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100323333","display_name":"Hui Zhang","orcid":"https://orcid.org/0000-0001-6028-2554","observed_orcids":["https://orcid.org/0000-0001-6028-2554"]},"institutions":[{"id":"https://openalex.org/I133999245","display_name":"University of Nevada, Las Vegas","ror":"https://ror.org/0406gha72","country_code":"US","type":"education","lineage":["https://openalex.org/I133999245"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hui Zhang","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, NV, 89154, USA. hui.zhang@unlv.edu","Department of Chemistry and Biochemistry, University of Nevada, 89154, Las Vegas, NV, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, NV, 89154, USA. hui.zhang@unlv.edu","institution_ids":["https://openalex.org/I133999245"]},{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of Nevada, 89154, Las Vegas, NV, USA","institution_ids":["https://openalex.org/I133999245"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042500101","display_name":"Shuiming Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuiming Li","raw_affiliation_strings":["Key Laboratory of Marine Bioresource & Ecology, College of Life Science, Shenzhen University, Shenzhen, 518060, China","Key Laboratory of Marine Bioresource & Ecology, College of Life Science, Shenzhen University, 518060, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Marine Bioresource & Ecology, College of Life Science, Shenzhen University, Shenzhen, 518060, China","institution_ids":["https://openalex.org/I180726961"]},{"raw_affiliation_string":"Key Laboratory of Marine Bioresource & Ecology, College of Life Science, Shenzhen University, 518060, Shenzhen, China","institution_ids":["https://openalex.org/I180726961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043502112","display_name":"Rongfeng Lan","orcid":"https://orcid.org/0000-0003-2124-7232","observed_orcids":["https://orcid.org/0000-0003-2124-7232"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I4210145292","display_name":"Shenzhen University Health Science Center","ror":"https://ror.org/04yjbr930","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210145292"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Rongfeng Lan","raw_affiliation_strings":["Department of Cell Biology & Medical Genetics, Shenzhen University Health Science Center, Shenzhen, 518071, China. lan@szu.edu.cn","Department of Cell Biology & Medical Genetics, Shenzhen University Health Science Center, 518071, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology & Medical Genetics, Shenzhen University Health Science Center, Shenzhen, 518071, China. lan@szu.edu.cn","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210145292"]},{"raw_affiliation_string":"Department of Cell Biology & Medical Genetics, Shenzhen University Health Science Center, 518071, Shenzhen, China","institution_ids":["https://openalex.org/I4210145292"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087766294","display_name":"Fei Lu","orcid":"https://orcid.org/0000-0001-5086-1157","observed_orcids":["https://orcid.org/0000-0001-5086-1157","https://orcid.org/0009-0007-8572-2465"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Fei Lu","raw_affiliation_strings":["State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China. lufei@pkusz.edu.cn","State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, 518055, Shenzhen, China"],"raw_orcid":"https://orcid.org/0000-0001-5086-1157","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China. lufei@pkusz.edu.cn","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, 518055, Shenzhen, China","institution_ids":["https://openalex.org/I20231570"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5043502112","https://openalex.org/A5087766294","https://openalex.org/A5100323333"],"corresponding_institution_ids":["https://openalex.org/I133999245","https://openalex.org/I180726961","https://openalex.org/I20231570","https://openalex.org/I4210145292"],"apc_list":{"value":4480,"currency":"USD","value_usd":4480},"apc_paid":null,"fwci":0.4443,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.58233332,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"98","issue":"12","first_page":"1627","last_page":"1641"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.3425000011920929,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.3425000011920929,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":0.29350000619888306,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.1234000027179718,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sox2","display_name":"SOX2","score":0.9290000200271606},{"id":"https://openalex.org/keywords/protein-stability","display_name":"protein stability","score":0.8820000290870667},{"id":"https://openalex.org/keywords/ubiquitination","display_name":"ubiquitination","score":0.9110000133514404},{"id":"https://openalex.org/keywords/histone-methyltransferase","display_name":"histone methyltransferase","score":0.828000009059906},{"id":"https://openalex.org/keywords/ovarian-teratoma","display_name":"ovarian teratoma","score":0.7620000243186951},{"id":"https://openalex.org/keywords/stem-cell-pluripotency","display_name":"stem cell pluripotency","score":0.8190000057220459},{"id":"https://openalex.org/keywords/tumor-initiation","display_name":"tumor initiation","score":0.6489999890327454},{"id":"https://openalex.org/keywords/rbbp5","display_name":"RBBP5","score":0.7160000205039978},{"id":"https://openalex.org/keywords/ash2l","display_name":"ASH2L","score":0.9950000047683716},{"id":"https://openalex.org/keywords/wdr5","display_name":"WDR5","score":0.8379999995231628},{"id":"https://openalex.org/keywords/pa-1-cells","display_name":"PA-1 cells","score":0.6140000224113464}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6002160310745239},{"id":"https://openalex.org/C119056186","wikidata":"https://www.wikidata.org/wiki/Q1431332","display_name":"Gene silencing","level":3,"score":0.5123575925827026},{"id":"https://openalex.org/C25602115","wikidata":"https://www.wikidata.org/wiki/Q407111","display_name":"Ubiquitin","level":3,"score":0.5092636346817017},{"id":"https://openalex.org/C2777933648","wikidata":"https://www.wikidata.org/wiki/Q21114866","display_name":"SOX2","level":4,"score":0.4903092682361603},{"id":"https://openalex.org/C134459356","wikidata":"https://www.wikidata.org/wiki/Q4274835","display_name":"Ubiquitin ligase","level":4,"score":0.44687914848327637},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3850519359111786},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.21982160210609436},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21029219031333923},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13433849811553955}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002868","descriptor_name":"Chromosomal Proteins, Non-Histone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008745","descriptor_name":"Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011495","descriptor_name":"Histone-Lysine N-Methyltransferase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013724","descriptor_name":"Teratoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016513","descriptor_name":"Mice, SCID","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016688","descriptor_name":"Mice, Inbred NOD","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D047908","descriptor_name":"Intracellular Signaling Peptides and Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051788","descriptor_name":"Myeloid-Lymphoid Leukemia Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D054875","descriptor_name":"Ubiquitination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055550","descriptor_name":"Protein Stability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055748","descriptor_name":"SOXB1 Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D057809","descriptor_name":"HEK293 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059748","descriptor_name":"Proteolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1038/s41374-018-0106-8","doi":"https://doi.org/10.1038/s41374-018-0106-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41374-018-0106-8","pdf_url":"https://www.nature.com/articles/s41374-018-0106-8.pdf","source":{"id":"https://openalex.org/S137146891","display_name":"Laboratory Investigation","issn_l":"0023-6837","issn":["0023-6837","1530-0307"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Laboratory Investigation","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13024356","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30089852/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13024356/pdf/nihms-2147839.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lab Invest","raw_type":"Text"},{"id":"pmid:30089852","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30089852","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Laboratory investigation; a journal of technical methods and pathology","raw_type":"Journal Article"},{"id":"pmh:oai:digitalscholarship.unlv.edu:chem_fac_articles-1236","doi":null,"is_oa":false,"landing_page_url":"https://digitalscholarship.unlv.edu/chem_fac_articles/237","pdf_url":null,"source":{"id":"https://openalex.org/S4377196371","display_name":"Digital Scholarship - UNLV (University of Nevada Reno)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I134113660","host_organization_name":"University of Nevada, Reno","host_organization_lineage":["https://openalex.org/I134113660"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Chemistry and Biochemistry Faculty Publications","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1038/s41374-018-0106-8","doi":"https://doi.org/10.1038/s41374-018-0106-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41374-018-0106-8","pdf_url":"https://www.nature.com/articles/s41374-018-0106-8.pdf","source":{"id":"https://openalex.org/S137146891","display_name":"Laboratory Investigation","issn_l":"0023-6837","issn":["0023-6837","1530-0307"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Laboratory Investigation","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.7246000170707703,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2449601139","display_name":"Control of Epigenetic Inheritance By Proteolysis","funder_award_id":"R15GM116087","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4337467711","display_name":null,"funder_award_id":"2014A030313779","funder_id":"https://openalex.org/F4320321921","funder_display_name":"Natural Science Foundation of Guangdong Province"},{"id":"https://openalex.org/G8515484367","display_name":"Regulation of Replication Checkpoint by Proteolysis","funder_award_id":"R01CA098955","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320321921","display_name":"Natural Science Foundation of Guangdong Province","ror":null},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2885287752.pdf","grobid_xml":"https://content.openalex.org/works/W2885287752.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W1965784662","https://openalex.org/W1978083226","https://openalex.org/W1978357765","https://openalex.org/W1992662525","https://openalex.org/W1994844375","https://openalex.org/W1995651729","https://openalex.org/W1999553354","https://openalex.org/W2020483734","https://openalex.org/W2023171799","https://openalex.org/W2029372290","https://openalex.org/W2031951376","https://openalex.org/W2034619626","https://openalex.org/W2037074464","https://openalex.org/W2038926092","https://openalex.org/W2039175440","https://openalex.org/W2042134265","https://openalex.org/W2042871287","https://openalex.org/W2043624735","https://openalex.org/W2049868369","https://openalex.org/W2052483400","https://openalex.org/W2054786727","https://openalex.org/W2066205648","https://openalex.org/W2071241326","https://openalex.org/W2075177970","https://openalex.org/W2075296132","https://openalex.org/W2079777624","https://openalex.org/W2086227529","https://openalex.org/W2098769593","https://openalex.org/W2107062469","https://openalex.org/W2107575419","https://openalex.org/W2110015307","https://openalex.org/W2125747506","https://openalex.org/W2125987139","https://openalex.org/W2127015656","https://openalex.org/W2141797256","https://openalex.org/W2146942715","https://openalex.org/W2148394396","https://openalex.org/W2150170782","https://openalex.org/W2165908624","https://openalex.org/W2168854899","https://openalex.org/W2168970170","https://openalex.org/W2169532116","https://openalex.org/W2171777194","https://openalex.org/W2210554177","https://openalex.org/W2410034240","https://openalex.org/W6681620667"],"related_works":["https://openalex.org/W2977131940","https://openalex.org/W2740417532","https://openalex.org/W2043624735","https://openalex.org/W3045724696","https://openalex.org/W7098111691","https://openalex.org/W2991314738","https://openalex.org/W4388828386","https://openalex.org/W7221024275","https://openalex.org/W2765272158","https://openalex.org/W3091687991"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-08-22T00:00:00"}