{"id":"https://openalex.org/W2885057333","doi":"https://doi.org/10.1056/nejmcps1803584","title":"A Headache of a Diagnosis","display_name":"A Headache of a Diagnosis","publication_year":2018,"publication_date":"2018-08-01","ids":{"openalex":"https://openalex.org/W2885057333","doi":"https://doi.org/10.1056/nejmcps1803584","mag":"2885057333","pmid":"https://pubmed.ncbi.nlm.nih.gov/30067932"},"language":"en","primary_location":{"id":"doi:10.1056/nejmcps1803584","doi":"https://doi.org/10.1056/nejmcps1803584","is_oa":false,"landing_page_url":"https://doi.org/10.1056/nejmcps1803584","pdf_url":null,"source":{"id":"https://openalex.org/S62468778","display_name":"New England Journal of Medicine","issn_l":"0028-4793","issn":["0028-4793","0096-6762","1533-4406","2331-4710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320239","host_organization_name":"Massachusetts Medical Society","host_organization_lineage":["https://openalex.org/P4310320239"],"host_organization_lineage_names":["Massachusetts Medical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"New England Journal of Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102929066","display_name":"Robert M. Stern","orcid":"https://orcid.org/0000-0001-7693-7738","observed_orcids":["https://orcid.org/0000-0001-7693-7738"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert M. Stern","raw_affiliation_strings":["From the Department of Medicine, Brigham and Women\u2019s Hospital, and Harvard Medical School \u2014 both in Boston","Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School \u2014 both in Boston"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine, Brigham and Women\u2019s Hospital, and Harvard Medical School \u2014 both in Boston","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School \u2014 both in Boston","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023296232","display_name":"Marlise Rachael Luskin","orcid":"https://orcid.org/0000-0002-5781-4529","observed_orcids":["https://orcid.org/0000-0002-5781-4529"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marlise R. Luskin","raw_affiliation_strings":["From the Department of Medicine, Brigham and Women\u2019s Hospital, and Harvard Medical School \u2014 both in Boston","Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School \u2014 both in Boston"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine, Brigham and Women\u2019s Hospital, and Harvard Medical School \u2014 both in Boston","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School \u2014 both in Boston","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111820833","display_name":"Roger P. Clark","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roger P. Clark","raw_affiliation_strings":["From the Department of Medicine, Brigham and Women\u2019s Hospital, and Harvard Medical School \u2014 both in Boston","Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School \u2014 both in Boston"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine, Brigham and Women\u2019s Hospital, and Harvard Medical School \u2014 both in Boston","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School \u2014 both in Boston","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072901982","display_name":"Amy Leigh Miller","orcid":"https://orcid.org/0000-0001-6685-3848","observed_orcids":["https://orcid.org/0000-0001-6685-3848"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy L. Miller","raw_affiliation_strings":["From the Department of Medicine, Brigham and Women\u2019s Hospital, and Harvard Medical School \u2014 both in Boston","Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School \u2014 both in Boston"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine, Brigham and Women\u2019s Hospital, and Harvard Medical School \u2014 both in Boston","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School \u2014 both in Boston","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028396638","display_name":"Joseph Loscalzo","orcid":"https://orcid.org/0000-0002-1153-8047","observed_orcids":["https://orcid.org/0000-0002-1153-8047"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph Loscalzo","raw_affiliation_strings":["From the Department of Medicine, Brigham and Women\u2019s Hospital, and Harvard Medical School \u2014 both in Boston","Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School \u2014 both in Boston"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medicine, Brigham and Women\u2019s Hospital, and Harvard Medical School \u2014 both in Boston","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School \u2014 both in Boston","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.5279,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.81795431,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"379","issue":"5","first_page":"475","last_page":"479"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13533","display_name":"Medical Case Reports and Studies","score":0.5609999895095825,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13533","display_name":"Medical Case Reports and Studies","score":0.5609999895095825,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11929","display_name":"Cerebral Venous Sinus Thrombosis","score":0.09080000221729279,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10498","display_name":"Migraine and Headache Studies","score":0.031700000166893005,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/headache","display_name":"headache","score":0.9290000200271606},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.746999979019165},{"id":"https://openalex.org/keywords/young-men","display_name":"young men","score":0.7009999752044678}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9153956174850464},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.33829399943351746},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.32646244764328003}],"mesh":[{"descriptor_ui":"D000637","descriptor_name":"Transaminases","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001772","descriptor_name":"Blood Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004199","descriptor_name":"Disease Vectors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004318","descriptor_name":"Doxycycline","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005076","descriptor_name":"Exanthema","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D005334","descriptor_name":"Fever","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006261","descriptor_name":"Headache","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012286","descriptor_name":"Rickettsia typhi","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013781","descriptor_name":"Texas","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014195","descriptor_name":"Travel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014437","descriptor_name":"Typhus, Endemic Flea-Borne","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D014437","descriptor_name":"Typhus, Endemic Flea-Borne","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D014437","descriptor_name":"Typhus, Endemic Flea-Borne","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D014437","descriptor_name":"Typhus, Endemic Flea-Borne","qualifier_ui":"Q000635","qualifier_name":"transmission","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1056/nejmcps1803584","doi":"https://doi.org/10.1056/nejmcps1803584","is_oa":false,"landing_page_url":"https://doi.org/10.1056/nejmcps1803584","pdf_url":null,"source":{"id":"https://openalex.org/S62468778","display_name":"New England Journal of Medicine","issn_l":"0028-4793","issn":["0028-4793","0096-6762","1533-4406","2331-4710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320239","host_organization_name":"Massachusetts Medical Society","host_organization_lineage":["https://openalex.org/P4310320239"],"host_organization_lineage_names":["Massachusetts Medical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"New England Journal of Medicine","raw_type":"journal-article"},{"id":"pmid:30067932","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30067932","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The New England journal of medicine","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1945461577","https://openalex.org/W2129071059","https://openalex.org/W2130396731","https://openalex.org/W2163255895","https://openalex.org/W2415833883","https://openalex.org/W2464931281","https://openalex.org/W2539971609","https://openalex.org/W2540836091","https://openalex.org/W2604594143","https://openalex.org/W2670930070"],"related_works":["https://openalex.org/W2205119928","https://openalex.org/W2336151607","https://openalex.org/W4399558045","https://openalex.org/W3172532168","https://openalex.org/W2407052642","https://openalex.org/W2415417192","https://openalex.org/W4252498906","https://openalex.org/W2743236838","https://openalex.org/W4289535237","https://openalex.org/W147538342"],"abstract_inverted_index":{"A":[0],"24-year-old":[1],"man":[2],"presented":[3],"to":[4],"a":[5,12],"university":[6],"health":[7],"center":[8],"in":[9],"January":[10],"with":[11],"persistent":[13],"headache":[14],"that":[15],"had":[16],"begun":[17],"abruptly":[18],"6":[19],"days":[20],"earlier.":[21]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-08-22T00:00:00"}