{"id":"https://openalex.org/W2884914701","doi":"https://doi.org/10.1016/j.ijid.2018.04.3524","title":"The persistence of the immune response following Ebola infection in Liberian survivors of the 2014-2015 outbreak","display_name":"The persistence of the immune response following Ebola infection in Liberian survivors of the 2014-2015 outbreak","publication_year":2018,"publication_date":"2018-07-27","ids":{"openalex":"https://openalex.org/W2884914701","doi":"https://doi.org/10.1016/j.ijid.2018.04.3524","mag":"2884914701"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijid.2018.04.3524","doi":"https://doi.org/10.1016/j.ijid.2018.04.3524","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijid.2018.04.3524","pdf_url":"http://www.ijidonline.com/article/S1201971218336087/pdf","source":{"id":"https://openalex.org/S35071406","display_name":"International Journal of Infectious Diseases","issn_l":"1201-9712","issn":["1201-9712","1878-3511"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://www.ijidonline.com/article/S1201971218336087/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082692743","display_name":"Yael Eskira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I124227911","display_name":"Ben-Gurion University of the Negev","ror":"https://ror.org/05tkyf982","country_code":"IL","type":"education","lineage":["https://openalex.org/I124227911"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Y. Eskira","raw_affiliation_strings":["Ben Gurion University of the Negev, Be\u2019er Sheva, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ben Gurion University of the Negev, Be\u2019er Sheva, Israel","institution_ids":["https://openalex.org/I124227911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002687453","display_name":"William A. Fischer","orcid":"https://orcid.org/0000-0002-4900-098X","observed_orcids":["https://orcid.org/0000-0002-4900-098X"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W.A.I. Fischer","raw_affiliation_strings":["Institute of Global Health and Infectious Diseases, The University of North Carolina, Chapel Hill, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Global Health and Infectious Diseases, The University of North Carolina, Chapel Hill, North Carolina, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113480606","display_name":"Ana I. Kuehne","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801122164","display_name":"United States Army Medical Research Institute of Infectious Diseases","ror":"https://ror.org/01pveve47","country_code":"US","type":"facility","lineage":["https://openalex.org/I106965489","https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I2801122164","https://openalex.org/I2802581893"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Kuehne","raw_affiliation_strings":["Virology Division\u2014U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virology Division\u2014U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA","institution_ids":["https://openalex.org/I2801122164"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060749170","display_name":"Jerry Brown","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J.F. Brown","raw_affiliation_strings":["Eternal Love Winning Africa Hospital, Paynesville, Liberia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eternal Love Winning Africa Hospital, Paynesville, Liberia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060375495","display_name":"Sam Tozay","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Tozay","raw_affiliation_strings":["Eternal Love Winning Africa Hospital, Paynesville, Liberia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eternal Love Winning Africa Hospital, Paynesville, Liberia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108821056","display_name":"Edwina Reeves","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. Reeves","raw_affiliation_strings":["Eternal Love Winning Africa Hospital, Paynesville, Liberia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eternal Love Winning Africa Hospital, Paynesville, Liberia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022272577","display_name":"Korto Pewu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K. Pewu","raw_affiliation_strings":["Eternal Love Winning Africa Hospital, Paynesville, Liberia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eternal Love Winning Africa Hospital, Paynesville, Liberia","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"D.L. Hoover","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158019","display_name":"Clinical Research Management","ror":"https://ror.org/05k7cyf48","country_code":"US","type":"other","lineage":["https://openalex.org/I4210158019"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D.L. Hoover","raw_affiliation_strings":["Clinical Research Management, Inc, Hinkley, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Management, Inc, Hinkley, OH, USA","institution_ids":["https://openalex.org/I4210158019"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016333842","display_name":"John M. Dye","orcid":"https://orcid.org/0000-0002-0883-5016","observed_orcids":["https://orcid.org/0000-0002-0883-5016"]},"institutions":[{"id":"https://openalex.org/I2801122164","display_name":"United States Army Medical Research Institute of Infectious Diseases","ror":"https://ror.org/01pveve47","country_code":"US","type":"facility","lineage":["https://openalex.org/I106965489","https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I2801122164","https://openalex.org/I2802581893"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.M. Dye","raw_affiliation_strings":["Virology Division\u2014U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Virology Division\u2014U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA","institution_ids":["https://openalex.org/I2801122164"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060710888","display_name":"David Alain Wohl","orcid":"https://orcid.org/0000-0002-7764-0212","observed_orcids":["https://orcid.org/0000-0002-7764-0212"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. Wohl","raw_affiliation_strings":["Institute of Global Health and Infectious Diseases, The University of North Carolina, Chapel Hill, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Global Health and Infectious Diseases, The University of North Carolina, Chapel Hill, North Carolina, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045222894","display_name":"Leslie I. Lobel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I124227911","display_name":"Ben-Gurion University of the Negev","ror":"https://ror.org/05tkyf982","country_code":"IL","type":"education","lineage":["https://openalex.org/I124227911"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"L. Lobel","raw_affiliation_strings":["Ben Gurion University of the Negev, Be\u2019er Sheva, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ben Gurion University of the Negev, Be\u2019er Sheva, Israel","institution_ids":["https://openalex.org/I124227911"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5082692743"],"corresponding_institution_ids":["https://openalex.org/I124227911"],"apc_list":{"value":2900,"currency":"USD","value_usd":2900},"apc_paid":{"value":2900,"currency":"USD","value_usd":2900},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.094853,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"73","issue":null,"first_page":"45","last_page":"45"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11581","display_name":"Viral Infections and Outbreaks Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11581","display_name":"Viral Infections and Outbreaks Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12047","display_name":"Viral Infections and Vectors","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ebola-virus-disease","display_name":"Ebola virus disease","score":0.9860000014305115},{"id":"https://openalex.org/keywords/immune-response-persistence","display_name":"immune response persistence","score":0.7730000019073486},{"id":"https://openalex.org/keywords/humoral-immunity","display_name":"humoral immunity","score":0.7379999756813049},{"id":"https://openalex.org/keywords/cell-mediated-immunity","display_name":"cell-mediated immunity","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ebola-survivors","display_name":"Ebola survivors","score":0.5929999947547913},{"id":"https://openalex.org/keywords/2014-west-african-ebola-outbreak","display_name":"2014 West Africa Ebola outbreak","score":0.8889999985694885},{"id":"https://openalex.org/keywords/protective-immunity","display_name":"protective immunity","score":0.6200000047683716},{"id":"https://openalex.org/keywords/liberia","display_name":"Liberia","score":0.5540000200271606}],"concepts":[{"id":"https://openalex.org/C2777469322","wikidata":"https://www.wikidata.org/wiki/Q8064876","display_name":"Ebola virus","level":3,"score":0.6911519765853882},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6607480645179749},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5960203409194946},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5681067109107971},{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.5373019576072693},{"id":"https://openalex.org/C14086860","wikidata":"https://www.wikidata.org/wiki/Q337120","display_name":"Neutralization","level":3,"score":0.5310968160629272},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.48929688334465027},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.48473355174064636},{"id":"https://openalex.org/C2781188995","wikidata":"https://www.wikidata.org/wiki/Q6934982","display_name":"Multiplex","level":2,"score":0.47626492381095886},{"id":"https://openalex.org/C2779261636","wikidata":"https://www.wikidata.org/wiki/Q7003054","display_name":"Neutralizing antibody","level":3,"score":0.45454829931259155},{"id":"https://openalex.org/C32611913","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Titer","level":3,"score":0.44658029079437256},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37195855379104614},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.ijid.2018.04.3524","doi":"https://doi.org/10.1016/j.ijid.2018.04.3524","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijid.2018.04.3524","pdf_url":"http://www.ijidonline.com/article/S1201971218336087/pdf","source":{"id":"https://openalex.org/S35071406","display_name":"International Journal of Infectious Diseases","issn_l":"1201-9712","issn":["1201-9712","1878-3511"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Infectious Diseases","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.ijid.2018.04.3524","doi":"https://doi.org/10.1016/j.ijid.2018.04.3524","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijid.2018.04.3524","pdf_url":"http://www.ijidonline.com/article/S1201971218336087/pdf","source":{"id":"https://openalex.org/S35071406","display_name":"International Journal of Infectious Diseases","issn_l":"1201-9712","issn":["1201-9712","1878-3511"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Infectious Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9907000064849854,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.7599999904632568,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2884914701.pdf","grobid_xml":"https://content.openalex.org/works/W2884914701.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2545066464","https://openalex.org/W4323873941","https://openalex.org/W3043931834","https://openalex.org/W2334936298","https://openalex.org/W3092676015","https://openalex.org/W2883658995","https://openalex.org/W4399041998","https://openalex.org/W3092709358","https://openalex.org/W2056071037","https://openalex.org/W7162409645"],"abstract_inverted_index":{"Background:":[0],"Recent":[1],"studies":[2],"suggest":[3],"that":[4],"both":[5],"humoral":[6],"and":[7],"cellular":[8],"immunity":[9],"are":[10,29],"critical":[11],"for":[12],"recovery":[13],"from":[14],"Ebola":[15,43],"virus":[16,44],"(EBOV)":[17],"infection":[18],"in":[19],"humans.":[20],"However,":[21],"the":[22,36,50],"determinants":[23],"of":[24,38],"a":[25],"protective":[26],"immune":[27,39],"profile":[28],"still":[30],"not":[31],"fully":[32],"understood.":[33],"We":[34],"investigated":[35],"persistence":[37],"responses":[40],"among":[41],"Liberian":[42],"disease":[45],"(EVD)":[46],"survivors":[47],"infected":[48],"during":[49],"2014-2016":[51],"West":[52],"African":[53],"outbreak.":[54]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2018-08-03T00:00:00"}