{"id":"https://openalex.org/W2884795428","doi":"https://doi.org/10.1371/journal.pone.0200685","title":"Genome-wide association studies of inflammatory bowel disease in German shepherd dogs","display_name":"Genome-wide association studies of inflammatory bowel disease in German shepherd dogs","publication_year":2018,"publication_date":"2018-07-20","ids":{"openalex":"https://openalex.org/W2884795428","doi":"https://doi.org/10.1371/journal.pone.0200685","mag":"2884795428","pmid":"https://pubmed.ncbi.nlm.nih.gov/30028859","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6054420"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0200685","doi":"https://doi.org/10.1371/journal.pone.0200685","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0200685","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0200685&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0200685&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084967794","display_name":"Atiyeh Peiravan","orcid":"https://orcid.org/0000-0002-7846-6690","observed_orcids":["https://orcid.org/0000-0002-7846-6690"]},"institutions":[{"id":"https://openalex.org/I124357947","display_name":"University of London","ror":"https://ror.org/04cw6st05","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947"]},{"id":"https://openalex.org/I133836048","display_name":"Royal Veterinary College","ror":"https://ror.org/01wka8n18","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I133836048"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Atiyeh Peiravan","raw_affiliation_strings":["Department of Pathology and Pathogen Biology, Royal Veterinary College, University of London, North Mymms, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-7846-6690","affiliations":[{"raw_affiliation_string":"Department of Pathology and Pathogen Biology, Royal Veterinary College, University of London, North Mymms, United Kingdom","institution_ids":["https://openalex.org/I124357947","https://openalex.org/I133836048"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072984614","display_name":"Francesca Bertolini","orcid":"https://orcid.org/0000-0003-4181-3895","observed_orcids":["https://orcid.org/0000-0003-4181-3895"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Francesca Bertolini","raw_affiliation_strings":["Department of Animal Science, Iowa State University, Ames, Iowa, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Science, Iowa State University, Ames, Iowa, United States of America","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106429555","display_name":"Max F. Rothschild","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Max F. Rothschild","raw_affiliation_strings":["Department of Animal Science, Iowa State University, Ames, Iowa, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Science, Iowa State University, Ames, Iowa, United States of America","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059162298","display_name":"Kenneth William Simpson","orcid":"https://orcid.org/0000-0002-9306-8420","observed_orcids":["https://orcid.org/0000-0002-9306-8420"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4210151139","display_name":"New York State College of Veterinary Medicine","ror":"https://ror.org/04r17kf39","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4210151139"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth W. Simpson","raw_affiliation_strings":["College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4210151139"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036496208","display_name":"Albert E. Jergens","orcid":"https://orcid.org/0000-0003-2375-8685","observed_orcids":["https://orcid.org/0000-0003-2375-8685"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Albert E. Jergens","raw_affiliation_strings":["College of Veterinary Medicine, Iowa State University, Ames, Iowa, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Iowa State University, Ames, Iowa, United States of America","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062945808","display_name":"Karin Allenspach","orcid":"https://orcid.org/0000-0002-2168-5809","observed_orcids":["https://orcid.org/0000-0002-2168-5809"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karin Allenspach","raw_affiliation_strings":["College of Veterinary Medicine, Iowa State University, Ames, Iowa, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Iowa State University, Ames, Iowa, United States of America","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061861242","display_name":"Dirk Werling","orcid":"https://orcid.org/0000-0001-5411-4044","observed_orcids":["https://orcid.org/0000-0001-5411-4044"]},"institutions":[{"id":"https://openalex.org/I124357947","display_name":"University of London","ror":"https://ror.org/04cw6st05","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947"]},{"id":"https://openalex.org/I133836048","display_name":"Royal Veterinary College","ror":"https://ror.org/01wka8n18","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I133836048"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Dirk Werling","raw_affiliation_strings":["Department of Pathology and Pathogen Biology, Royal Veterinary College, University of London, North Mymms, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Pathogen Biology, Royal Veterinary College, University of London, North Mymms, United Kingdom","institution_ids":["https://openalex.org/I124357947","https://openalex.org/I133836048"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5084967794"],"corresponding_institution_ids":["https://openalex.org/I124357947","https://openalex.org/I133836048"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":2.9125,"has_fulltext":true,"cited_by_count":41,"citation_normalized_percentile":{"value":0.915898,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"13","issue":"7","first_page":"e0200685","last_page":"e0200685"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.33570000529289246,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.33570000529289246,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.2070000022649765,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.13099999725818634,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/canine-inflammatory-bowel-disease","display_name":"canine inflammatory bowel disease","score":0.9829999804496765},{"id":"https://openalex.org/keywords/german-shepherd-dog","display_name":"German Shepherd","score":0.9470000267028809},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.8270000219345093},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9750000238418579},{"id":"https://openalex.org/keywords/candidate-genes","display_name":"candidate genes","score":0.7549999952316284},{"id":"https://openalex.org/keywords/pathway-analysis","display_name":"pathway analysis","score":0.5860000252723694},{"id":"https://openalex.org/keywords/canine-genomics","display_name":"canine genomics","score":0.6800000071525574},{"id":"https://openalex.org/keywords/intestinal-immunity","display_name":"intestinal immunity","score":0.5550000071525574},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.7409999966621399}],"concepts":[{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.8403348922729492},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.7913068532943726},{"id":"https://openalex.org/C139275648","wikidata":"https://www.wikidata.org/wiki/Q17134011","display_name":"SNP","level":5,"score":0.7433168888092041},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6547613143920898},{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.6493310928344727},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6299482583999634},{"id":"https://openalex.org/C2778260677","wikidata":"https://www.wikidata.org/wiki/Q917447","display_name":"Inflammatory bowel disease","level":3,"score":0.6194822788238525},{"id":"https://openalex.org/C122060243","wikidata":"https://www.wikidata.org/wiki/Q7391885","display_name":"SNP array","level":5,"score":0.6161462068557739},{"id":"https://openalex.org/C163691529","wikidata":"https://www.wikidata.org/wiki/Q7391886","display_name":"SNP genotyping","level":5,"score":0.5815017819404602},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.5550468564033508},{"id":"https://openalex.org/C69991583","wikidata":"https://www.wikidata.org/wiki/Q1423575","display_name":"Candidate gene","level":3,"score":0.5287739038467407},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.4024817943572998},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3545153737068176},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.27258145809173584},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.22321033477783203},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.114439457654953}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015212","descriptor_name":"Inflammatory Bowel Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015212","descriptor_name":"Inflammatory Bowel Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015212","descriptor_name":"Inflammatory Bowel Diseases","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060005","descriptor_name":"Genotyping Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":9,"locations":[{"id":"doi:10.1371/journal.pone.0200685","doi":"https://doi.org/10.1371/journal.pone.0200685","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0200685","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0200685&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5013648","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6054420","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6054420","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6054420","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmid:30028859","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30028859","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:researchonline.rvc.ac.uk:11610","doi":null,"is_oa":true,"landing_page_url":"https://researchonline.rvc.ac.uk/id/eprint/11610/1/11610.pdf","pdf_url":"https://researchonline.rvc.ac.uk/id/eprint/11610/1/11610.pdf","source":{"id":"https://openalex.org/S4306402069","display_name":"RVC Research Online (Royal Veterinary College)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I133836048","host_organization_name":"Royal Veterinary College","host_organization_lineage":["https://openalex.org/I133836048"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:lib.dr.iastate.edu:ans_pubs-1450","doi":null,"is_oa":true,"landing_page_url":"https://lib.dr.iastate.edu/ans_pubs/456","pdf_url":null,"source":{"id":"https://openalex.org/S4377196104","display_name":"Iowa State University Digital Repository (Iowa State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I173911158","host_organization_name":"Iowa State University","host_organization_lineage":["https://openalex.org/I173911158"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Animal Science Publications","raw_type":"text"},{"id":"pmh:oai:cris.unibo.it:11585/903563","doi":null,"is_oa":true,"landing_page_url":"https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0200685","pdf_url":null,"source":{"id":"https://openalex.org/S4306402579","display_name":"Archivio istituzionale della ricerca (Alma Mater Studiorum Universit\u00e0 di Bologna)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210117483","host_organization_name":"Istituto di Ematologia di Bologna","host_organization_lineage":["https://openalex.org/I4210117483"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:c1fa3035a35a4e868a65bb0a5666f0d1","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c1fa3035a35a4e868a65bb0a5666f0d1","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 13, Iss 7, p e0200685 (2018)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/6846122","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Genome-wide_association_studies_of_inflammatory_bowel_disease_in_German_shepherd_dogs/6846122","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0200685","doi":"https://doi.org/10.1371/journal.pone.0200685","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0200685","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0200685&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8560000061988831,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7484754211","display_name":null,"funder_award_id":"1532250","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G8323984858","display_name":"Correlation of genotype with phenotype: Moving towards individualized pharmacogenomic treatment for canine inflammatory bowel disease (IBD)","funder_award_id":"BB/J01236X/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2884795428.pdf","grobid_xml":"https://content.openalex.org/works/W2884795428.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W200570263","https://openalex.org/W1481475489","https://openalex.org/W1485171755","https://openalex.org/W1546448788","https://openalex.org/W1553269519","https://openalex.org/W1592771441","https://openalex.org/W1603555904","https://openalex.org/W1901931884","https://openalex.org/W1946093640","https://openalex.org/W1984290997","https://openalex.org/W1986661099","https://openalex.org/W1989210966","https://openalex.org/W2013333236","https://openalex.org/W2017219759","https://openalex.org/W2024270260","https://openalex.org/W2027590052","https://openalex.org/W2031444238","https://openalex.org/W2041104984","https://openalex.org/W2058261716","https://openalex.org/W2059931557","https://openalex.org/W2062811432","https://openalex.org/W2066286673","https://openalex.org/W2075359127","https://openalex.org/W2077131078","https://openalex.org/W2077417036","https://openalex.org/W2078621117","https://openalex.org/W2080627540","https://openalex.org/W2084450567","https://openalex.org/W2084571346","https://openalex.org/W2085024301","https://openalex.org/W2100726669","https://openalex.org/W2104201959","https://openalex.org/W2105566590","https://openalex.org/W2109558235","https://openalex.org/W2119444539","https://openalex.org/W2120029762","https://openalex.org/W2125626931","https://openalex.org/W2130865756","https://openalex.org/W2137108495","https://openalex.org/W2143625465","https://openalex.org/W2147250941","https://openalex.org/W2147421609","https://openalex.org/W2151088711","https://openalex.org/W2161245845","https://openalex.org/W2161633633","https://openalex.org/W2166493810","https://openalex.org/W2169503950","https://openalex.org/W2180023734","https://openalex.org/W2319712731","https://openalex.org/W2413897106","https://openalex.org/W2535232573","https://openalex.org/W4206454098","https://openalex.org/W4238416248","https://openalex.org/W4244329277","https://openalex.org/W4245277907","https://openalex.org/W4252448776","https://openalex.org/W4253323169","https://openalex.org/W4254876936","https://openalex.org/W4391200511"],"related_works":["https://openalex.org/W4413020856","https://openalex.org/W2535232573","https://openalex.org/W7095859811","https://openalex.org/W2041104984","https://openalex.org/W2109558235","https://openalex.org/W2080627540","https://openalex.org/W2077131078","https://openalex.org/W3094770586","https://openalex.org/W2070327151","https://openalex.org/W2020188906"],"abstract_inverted_index":{"Canine":[0,106],"Inflammatory":[1],"Bowel":[2],"Disease":[3],"(IBD)":[4],"is":[5],"considered":[6],"a":[7,76,186,192],"multifactorial":[8],"disease":[9],"caused":[10],"by":[11,155,177],"complex":[12],"interactions":[13],"between":[14],"the":[15,39,47,53,56,105,149,166,169,173],"intestinal":[16,19],"immune":[17],"system,":[18],"microbiota":[20],"and":[21,94,100,111,120,125,139,164,168,191],"environmental":[22],"factors":[23],"in":[24,38,203,215],"genetically":[25],"susceptible":[26],"individuals.":[27],"Although":[28],"IBD":[29,74,133,214],"can":[30],"affect":[31],"any":[32],"breed,":[33],"German":[34],"shepherd":[35],"dogs":[36],"(GSD)":[37],"UK":[40],"are":[41],"at":[42],"increased":[43],"risk":[44],"of":[45,55,91,98,148,172,188,194],"developing":[46],"disease.":[48],"Based":[49],"on":[50,104,122],"previous":[51],"evidence,":[52],"aim":[54],"present":[57],"study":[58,79],"was":[59,83,102,114],"to":[60,73,129,200],"identify":[61],"single":[62,156],"nucleotide":[63],"polymorphisms":[64],"(SNPs),":[65],"which":[66],"may":[67],"confer":[68],"genetic":[69],"susceptibility":[70],"or":[71,88],"resistance":[72],"using":[75,116,134],"genome-wide":[77],"association":[78,137],"(GWAS).":[80],"Genomic":[81],"DNA":[82],"extracted":[84],"from":[85],"EDTA":[86],"blood":[87],"saliva":[89],"samples":[90],"96":[92],"cases":[93,99],"98":[95],"controls.":[96],"Genotyping":[97],"controls":[101],"performed":[103],"Illumina":[107],"HD":[108],"SNP":[109,157],"array":[110],"data":[112],"generated":[113],"analyzed":[115],"PLINK.":[117],"Several":[118],"SNPs":[119],"regions":[121,175],"chromosomes":[123],"7,9,11":[124],"13":[126],"were":[127],"detected":[128],"be":[130,201],"associated":[131,174,212],"with":[132,213],"different":[135],"SNP-by-SNP":[136],"methods":[138],"FST":[140,178],"windows":[141,179],"approach.":[142],"Searching":[143],"one":[144],"Mb":[145],"up-and":[146],"down-stream":[147],"most":[150],"significant":[151],"SNPs,":[152],"as":[153,159,161],"identified":[154,176,182,207],"analysis":[158,190],"well":[160],"200Kb":[162],"before":[163],"after":[165],"start":[167],"end":[170],"position":[171],"approach,":[180],"we":[181,206],"63":[183],"genes.":[184],"Using":[185],"combination":[187],"pathways":[189],"list":[193],"genes":[195,210],"that":[196],"have":[197],"been":[198],"reported":[199],"involved":[202],"human":[204],"IBD,":[205],"16":[208],"candidate":[209],"potentially":[211],"GSD.":[216]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-08-03T00:00:00"}