{"id":"https://openalex.org/W2884764098","doi":null,"title":"Abstract 20062: Endothelial Smad4 Contributes to Beiging of White Adipose Tissue by Regulating Angiogenesis and Adipogenic Precursor Proliferation","display_name":"Abstract 20062: Endothelial Smad4 Contributes to Beiging of White Adipose Tissue by Regulating Angiogenesis and Adipogenic Precursor Proliferation","publication_year":2017,"publication_date":"2017-11-14","ids":{"openalex":"https://openalex.org/W2884764098","mag":"2884764098"},"language":"en","primary_location":{"id":"mag:2884764098","doi":null,"is_oa":false,"landing_page_url":"https://www.ahajournals.org/doi/10.1161/circ.136.suppl_1.20062","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015080274","display_name":"Xiao Yu Tian","orcid":"https://orcid.org/0000-0003-3472-9898","observed_orcids":["https://orcid.org/0000-0003-3472-9898"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Xiao Yu Tian","raw_affiliation_strings":["School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, Hong Kong"],"raw_orcid":"https://orcid.org/0000-0003-3472-9898","affiliations":[{"raw_affiliation_string":"School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077013869","display_name":"Hongsong Zhang","orcid":"https://orcid.org/0000-0003-4251-7609","observed_orcids":["https://orcid.org/0000-0003-4251-7609"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Hongsong Zhang","raw_affiliation_strings":["School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, Hong Kong"],"raw_orcid":"https://orcid.org/0000-0003-4251-7609","affiliations":[{"raw_affiliation_string":"School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100329690","display_name":"Chenguang Wang","orcid":"https://orcid.org/0000-0002-4554-7152","observed_orcids":["https://orcid.org/0000-0002-4554-7152"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Chenguang Wang","raw_affiliation_strings":["School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, Hong Kong"],"raw_orcid":"https://orcid.org/0000-0002-4554-7152","affiliations":[{"raw_affiliation_string":"School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058970294","display_name":"Mingyu Huo","orcid":"https://orcid.org/0000-0002-2817-8391","observed_orcids":["https://orcid.org/0000-0002-2817-8391"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Mingyu Huo","raw_affiliation_strings":["School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, Hong Kong"],"raw_orcid":"https://orcid.org/0000-0002-2817-8391","affiliations":[{"raw_affiliation_string":"School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100447655","display_name":"Ronald C.W.","orcid":"https://orcid.org/0000-0002-1227-803X","observed_orcids":["https://orcid.org/0000-0002-1227-803X"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Ronald C.W.","raw_affiliation_strings":["Department of Medicine & Therapeutics, Chinese University of Hong Kong, Hong Kong, Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine & Therapeutics, Chinese University of Hong Kong, Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108067820","display_name":"Y\u00fc Huang","orcid":"https://orcid.org/0000-0002-1277-6784","observed_orcids":["https://orcid.org/0000-0002-1277-6784"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Y\u00fc Huang","raw_affiliation_strings":["School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, Hong Kong"],"raw_orcid":"https://orcid.org/0000-0002-1277-6784","affiliations":[{"raw_affiliation_string":"School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I177725633"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I177725633"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"136","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12979","display_name":"Cardiovascular Disease and Adiposity","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/smad4","display_name":"SMAD4","score":0.9409999847412109},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.9350000023841858},{"id":"https://openalex.org/keywords/white-adipose-tissue","display_name":"white adipose tissue","score":0.7860000133514404},{"id":"https://openalex.org/keywords/brown-adipose-tissue","display_name":"brown adipose tissue","score":0.7929999828338623},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.9480000138282776},{"id":"https://openalex.org/keywords/cold-stress","display_name":"cold stress","score":0.9010000228881836},{"id":"https://openalex.org/keywords/ucp1","display_name":"UCP1","score":0.8859999775886536},{"id":"https://openalex.org/keywords/thermogenesis","display_name":"thermogenesis","score":0.46000000834465027}],"concepts":[{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.8501461744308472},{"id":"https://openalex.org/C122927707","wikidata":"https://www.wikidata.org/wiki/Q2824461","display_name":"Adipogenesis","level":3,"score":0.7630834579467773},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7443979978561401},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.6827518343925476},{"id":"https://openalex.org/C151955695","wikidata":"https://www.wikidata.org/wiki/Q654528","display_name":"White adipose tissue","level":3,"score":0.6397050619125366},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4251159429550171},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.41993483901023865},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.38882219791412354},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13646158576011658}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2884764098","doi":null,"is_oa":false,"landing_page_url":"https://www.ahajournals.org/doi/10.1161/circ.136.suppl_1.20062","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4288472744","https://openalex.org/W4321769006","https://openalex.org/W3030178421","https://openalex.org/W3083856237","https://openalex.org/W2943889599","https://openalex.org/W3146463257","https://openalex.org/W2953047519","https://openalex.org/W2593905561","https://openalex.org/W2948034670","https://openalex.org/W1636028564"],"abstract_inverted_index":{"Introduction:":[0],"Cold":[1],"stress":[2],"increases":[3],"adrenergic":[4],"stimulation":[5],"of":[6],"white":[7],"adipose":[8,23],"tissue":[9,24],"(WAT)":[10],"by":[11],"upregulating":[12],"uncoupling":[13],"protein":[14],"1":[15],"(UCP1)":[16],"to":[17],"transform":[18],"WAT":[19],"into":[20],"a":[21],"brown":[22],"-like":[25],"phenotype,":[26],"or...":[27]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-08-03T00:00:00"}