{"id":"https://openalex.org/W2884736975","doi":null,"title":"Epidermal mucus, a major determinant in fish health: a review.","display_name":"Epidermal mucus, a major determinant in fish health: a review.","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2884736975","mag":"2884736975","pmid":"https://pubmed.ncbi.nlm.nih.gov/30046316","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6056142"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:5011741","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6056142","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6056142","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018100036","display_name":"Supriya Dash","orcid":"https://orcid.org/0000-0001-6061-335X","observed_orcids":["https://orcid.org/0000-0001-6061-335X"]},"institutions":[{"id":"https://openalex.org/I4028839","display_name":"Biju Patnaik University of Technology","ror":"https://ror.org/03vqjtg68","country_code":"IN","type":"education","lineage":["https://openalex.org/I4028839"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"S Dash","raw_affiliation_strings":["Department of Biotechnology, College of Engineering and Technology, Biju Patnaik University of Technology, Bhubaneswar, Odisha-751003, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, College of Engineering and Technology, Biju Patnaik University of Technology, Bhubaneswar, Odisha-751003, India","institution_ids":["https://openalex.org/I4028839"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083358477","display_name":"Swagat Kumar Das","orcid":"https://orcid.org/0000-0002-9744-9992","observed_orcids":["https://orcid.org/0000-0002-9744-9992"]},"institutions":[{"id":"https://openalex.org/I4028839","display_name":"Biju Patnaik University of Technology","ror":"https://ror.org/03vqjtg68","country_code":"IN","type":"education","lineage":["https://openalex.org/I4028839"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"S K Das","raw_affiliation_strings":["Department of Biotechnology, College of Engineering and Technology, Biju Patnaik University of Technology, Bhubaneswar, Odisha-751003, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, College of Engineering and Technology, Biju Patnaik University of Technology, Bhubaneswar, Odisha-751003, India","institution_ids":["https://openalex.org/I4028839"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008447219","display_name":"Juhi Samal","orcid":"https://orcid.org/0000-0002-1030-9066","observed_orcids":["https://orcid.org/0000-0002-1030-9066"]},"institutions":[{"id":"https://openalex.org/I188760350","display_name":"Ollscoil na Gaillimhe \u2013 University of Galway","ror":"https://ror.org/03bea9k73","country_code":"IE","type":"education","lineage":["https://openalex.org/I188760350"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"J Samal","raw_affiliation_strings":["Ph.D. Student, Network of Excellence for Functional Biomaterials, National University of Ireland, Galway, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ph.D. Student, Network of Excellence for Functional Biomaterials, National University of Ireland, Galway, Ireland","institution_ids":["https://openalex.org/I188760350"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061398571","display_name":"Hrudayanath Thatoi","orcid":"https://orcid.org/0000-0002-3368-1266","observed_orcids":["https://orcid.org/0000-0002-3368-1266","https://orcid.org/0000-0003-1345-9542"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H N Thatoi","raw_affiliation_strings":["Department of Biotechnology, North Orissa University, Baripada, Odisha-757003, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, North Orissa University, Baripada, Odisha-757003, India","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":7.9906,"has_fulltext":false,"cited_by_count":221,"citation_normalized_percentile":{"value":0.98505179,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"19","issue":"2","first_page":"72","last_page":"81"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11403","display_name":"Invertebrate Immune Response Mechanisms","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.8379999995231628},{"id":"https://openalex.org/keywords/goblet-cells","display_name":"goblet cells","score":0.8169999718666077},{"id":"https://openalex.org/keywords/antimicrobial-peptides","display_name":"antimicrobial peptides","score":0.9900000095367432},{"id":"https://openalex.org/keywords/lysozyme","display_name":"lysozyme","score":0.859000027179718},{"id":"https://openalex.org/keywords/protease","display_name":"proteolytic enzymes","score":0.7630000114440918},{"id":"https://openalex.org/keywords/lectins","display_name":"lectins","score":0.9890000224113464},{"id":"https://openalex.org/keywords/fish-disease","display_name":"fish disease","score":0.38199999928474426},{"id":"https://openalex.org/keywords/mucosal-protection","display_name":"mucosal protection","score":0.46399998664855957}],"concepts":[{"id":"https://openalex.org/C2777312293","wikidata":"https://www.wikidata.org/wiki/Q3649349","display_name":"Mucus","level":2,"score":0.922156572341919},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.8601343631744385},{"id":"https://openalex.org/C182220744","wikidata":"https://www.wikidata.org/wiki/Q7251226","display_name":"Proteases","level":3,"score":0.8107872009277344},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7018138766288757},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6365867853164673},{"id":"https://openalex.org/C540938839","wikidata":"https://www.wikidata.org/wiki/Q1201508","display_name":"Antimicrobial peptides","level":3,"score":0.5950564742088318},{"id":"https://openalex.org/C2777379352","wikidata":"https://www.wikidata.org/wiki/Q24739493","display_name":"Cathelicidin","level":4,"score":0.415755033493042},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.38858792185783386},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.38365641236305237},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.24257725477218628},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.1281442642211914},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11875876784324646},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:5011741","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6056142","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6056142","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6056142","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Iran J Vet Res","raw_type":"Text"},{"id":"pmid:30046316","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30046316","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Iranian journal of veterinary research","raw_type":"Journal Article"},{"id":"mag:2884736975","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30046316","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5011741","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6056142","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":87,"referenced_works":["https://openalex.org/W756437733","https://openalex.org/W793726672","https://openalex.org/W1515090721","https://openalex.org/W1524238603","https://openalex.org/W1564772866","https://openalex.org/W1627878190","https://openalex.org/W1818830552","https://openalex.org/W1820519791","https://openalex.org/W1964991450","https://openalex.org/W1965148589","https://openalex.org/W1965648478","https://openalex.org/W1965971767","https://openalex.org/W1966234387","https://openalex.org/W1968244390","https://openalex.org/W1974073103","https://openalex.org/W1975817646","https://openalex.org/W1977358487","https://openalex.org/W1982514550","https://openalex.org/W1984521113","https://openalex.org/W1984680821","https://openalex.org/W1985448984","https://openalex.org/W1988044861","https://openalex.org/W1988398601","https://openalex.org/W1990145134","https://openalex.org/W1993187430","https://openalex.org/W1994858966","https://openalex.org/W1997134717","https://openalex.org/W1997217173","https://openalex.org/W2000228858","https://openalex.org/W2000965673","https://openalex.org/W2004373761","https://openalex.org/W2005757610","https://openalex.org/W2008164830","https://openalex.org/W2010284183","https://openalex.org/W2010407091","https://openalex.org/W2013633252","https://openalex.org/W2013833224","https://openalex.org/W2014643461","https://openalex.org/W2019464849","https://openalex.org/W2021584723","https://openalex.org/W2022020355","https://openalex.org/W2025063713","https://openalex.org/W2026664617","https://openalex.org/W2029862562","https://openalex.org/W2031049621","https://openalex.org/W2033933930","https://openalex.org/W2039706099","https://openalex.org/W2040153411","https://openalex.org/W2043960204","https://openalex.org/W2045030680","https://openalex.org/W2046358537","https://openalex.org/W2048418045","https://openalex.org/W2048780836","https://openalex.org/W2049483788","https://openalex.org/W2052439409","https://openalex.org/W2053706055","https://openalex.org/W2053916736","https://openalex.org/W2054412506","https://openalex.org/W2057686596","https://openalex.org/W2062954479","https://openalex.org/W2066785761","https://openalex.org/W2068379376","https://openalex.org/W2070062955","https://openalex.org/W2070550105","https://openalex.org/W2074078315","https://openalex.org/W2078664576","https://openalex.org/W2079809606","https://openalex.org/W2080267300","https://openalex.org/W2080304425","https://openalex.org/W2085136523","https://openalex.org/W2091366683","https://openalex.org/W2091555639","https://openalex.org/W2093850976","https://openalex.org/W2095260089","https://openalex.org/W2096542971","https://openalex.org/W2103034068","https://openalex.org/W2103302348","https://openalex.org/W2118076841","https://openalex.org/W2121906599","https://openalex.org/W2144225366","https://openalex.org/W2149401354","https://openalex.org/W2151405634","https://openalex.org/W2158637505","https://openalex.org/W2173882015","https://openalex.org/W2327229862","https://openalex.org/W4238980148","https://openalex.org/W4255507877"],"related_works":["https://openalex.org/W7034611426","https://openalex.org/W2588473628","https://openalex.org/W4381609934","https://openalex.org/W7065024572","https://openalex.org/W2343215646","https://openalex.org/W4294097356","https://openalex.org/W2033933930","https://openalex.org/W2047217315","https://openalex.org/W7172199442","https://openalex.org/W3041226444"],"abstract_inverted_index":{"Fish":[0],"epidermal":[1,65,167],"mucus":[2,35,43,66,92,128,168],"contains":[3,45],"innate":[4,59,119,134],"immune":[5],"components,":[6],"secreted":[7,63],"by":[8,64,99,104],"globlet":[9],"cells":[10,67],"that":[11,57,113],"provide":[12,58,158],"the":[13,97,153,163],"primary":[14],"defence":[15],"against":[16,71],"different":[17,87,164],"pathogenic":[18],"microbes":[19],"and":[20,27,38,135,142],"act":[21],"as":[22,49,173,175],"a":[23,72,115,159],"barrier":[24],"between":[25],"fish":[26,94,130],"its":[28,101],"immediate":[29],"niche.":[30],"The":[31,42,61,150],"major":[32],"function":[33],"of":[34,40,74,93,124,152,162,166,178],"includes":[36],"entrapment":[37],"sloughing":[39],"microbes.":[41],"also":[44,110],"many":[46],"factors":[47],"such":[48],"antimicrobial":[50,69],"peptides":[51],"(AMPs),":[52],"lysozymes,":[53],"lectins,":[54],"proteases,":[55,171],"etc":[56],"immunity.":[60],"AMPs":[62],"displayed":[68],"activity":[70],"variety":[73],"pathogens.":[75,181],"Besides,":[76],"mucosal":[77,111],"lysozyme":[78],"was":[79],"found":[80,89,144],"to":[81,145,157],"produce":[82],"significant":[83],"bacteriolytic":[84],"action":[85,179],"whereas":[86],"proteases":[88],"in":[90,118,129],"skin":[91],"can":[95],"kill":[96],"pathogens":[98],"cleaving":[100],"protein":[102],"or":[103],"activating":[105],"immunological":[106],"mechanisms.":[107],"Lectins":[108],"are":[109],"agglutinins":[112],"play":[114],"diverse":[116],"role":[117],"immunity":[120],"like":[121],"opsonization,":[122],"activation":[123],"complement,":[125],"etc.":[126],"Epidermal":[127],"thus":[131],"provides":[132],"an":[133],"fast":[136],"acting":[137],"protection":[138],"which":[139],"is":[140,143,156],"non-specific":[141],"be":[146],"relatively":[147],"temperature":[148],"independent.":[149],"aim":[151],"present":[154],"review":[155],"broad":[160],"overview":[161],"components":[165],"including":[169],"AMPs,":[170],"lysozymes":[172],"well":[174],"their":[176],"mode":[177],"on":[180]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":21},{"year":2024,"cited_by_count":42},{"year":2023,"cited_by_count":49},{"year":2022,"cited_by_count":25},{"year":2021,"cited_by_count":35},{"year":2020,"cited_by_count":28},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-08-03T00:00:00"}