{"id":"https://openalex.org/W2884499015","doi":"https://doi.org/10.1074/jbc.ra118.002321","title":"Regulation of monoamine oxidase A (MAO-A) expression, activity, and function in IL-13\u2013stimulated monocytes and A549 lung carcinoma cells","display_name":"Regulation of monoamine oxidase A (MAO-A) expression, activity, and function in IL-13\u2013stimulated monocytes and A549 lung carcinoma cells","publication_year":2018,"publication_date":"2018-07-18","ids":{"openalex":"https://openalex.org/W2884499015","doi":"https://doi.org/10.1074/jbc.ra118.002321","mag":"2884499015","pmid":"https://pubmed.ncbi.nlm.nih.gov/30021838","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6130935"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.ra118.002321","doi":"https://doi.org/10.1074/jbc.ra118.002321","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.ra118.002321","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1074/jbc.ra118.002321","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091749133","display_name":"Sukhamoy Dhabal","orcid":"https://orcid.org/0000-0003-0665-9992","observed_orcids":["https://orcid.org/0000-0003-0665-9992"]},"institutions":[{"id":"https://openalex.org/I155837530","display_name":"National Institute of Technology Durgapur","ror":"https://ror.org/04ds0jm32","country_code":"IN","type":"education","lineage":["https://openalex.org/I155837530"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sukhamoy Dhabal","raw_affiliation_strings":["From the Department of Biotechnology, National Institute of Technology-Durgapur, Mahatma Gandhi Avenue, Durgapur-713209, Burdwan, West Bengal, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Biotechnology, National Institute of Technology-Durgapur, Mahatma Gandhi Avenue, Durgapur-713209, Burdwan, West Bengal, India","institution_ids":["https://openalex.org/I155837530"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Pradip Das","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I155837530","display_name":"National Institute of Technology Durgapur","ror":"https://ror.org/04ds0jm32","country_code":"IN","type":"education","lineage":["https://openalex.org/I155837530"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pradip Das","raw_affiliation_strings":["From the Department of Biotechnology, National Institute of Technology-Durgapur, Mahatma Gandhi Avenue, Durgapur-713209, Burdwan, West Bengal, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Biotechnology, National Institute of Technology-Durgapur, Mahatma Gandhi Avenue, Durgapur-713209, Burdwan, West Bengal, India","institution_ids":["https://openalex.org/I155837530"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Pritam Biswas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I155837530","display_name":"National Institute of Technology Durgapur","ror":"https://ror.org/04ds0jm32","country_code":"IN","type":"education","lineage":["https://openalex.org/I155837530"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pritam Biswas","raw_affiliation_strings":["From the Department of Biotechnology, National Institute of Technology-Durgapur, Mahatma Gandhi Avenue, Durgapur-713209, Burdwan, West Bengal, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Biotechnology, National Institute of Technology-Durgapur, Mahatma Gandhi Avenue, Durgapur-713209, Burdwan, West Bengal, India","institution_ids":["https://openalex.org/I155837530"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101057566","display_name":"Priyanka Kumari","orcid":"https://orcid.org/0009-0005-6724-2551","observed_orcids":["https://orcid.org/0009-0005-6724-2551"]},"institutions":[{"id":"https://openalex.org/I155837530","display_name":"National Institute of Technology Durgapur","ror":"https://ror.org/04ds0jm32","country_code":"IN","type":"education","lineage":["https://openalex.org/I155837530"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Priyanka Kumari","raw_affiliation_strings":["From the Department of Biotechnology, National Institute of Technology-Durgapur, Mahatma Gandhi Avenue, Durgapur-713209, Burdwan, West Bengal, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Biotechnology, National Institute of Technology-Durgapur, Mahatma Gandhi Avenue, Durgapur-713209, Burdwan, West Bengal, India","institution_ids":["https://openalex.org/I155837530"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082188638","display_name":"Valentin P. Yakubenko","orcid":"https://orcid.org/0000-0002-0242-3061","observed_orcids":["https://orcid.org/0000-0002-0242-3061"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I36373038","display_name":"Cleveland Clinic Lerner College of Medicine","ror":"https://ror.org/02x4b0932","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750","https://openalex.org/I36373038"]},{"id":"https://openalex.org/I4405287411","display_name":"Cleveland Clinic Research","ror":"https://ror.org/053229s83","country_code":"US","type":"facility","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Valentin P. Yakubenko","raw_affiliation_strings":["the Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195, and","Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195, and","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I36373038","https://openalex.org/I4405287411","https://openalex.org/I58956616"]},{"raw_affiliation_string":"Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I36373038","https://openalex.org/I4405287411","https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025216603","display_name":"Suman Kundu","orcid":"https://orcid.org/0000-0002-8591-1166","observed_orcids":["https://orcid.org/0000-0002-8591-1166"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I36373038","display_name":"Cleveland Clinic Lerner College of Medicine","ror":"https://ror.org/02x4b0932","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750","https://openalex.org/I36373038"]},{"id":"https://openalex.org/I4405287411","display_name":"Cleveland Clinic Research","ror":"https://ror.org/053229s83","country_code":"US","type":"facility","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suman Kundu","raw_affiliation_strings":["the Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195, and","Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195, and","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I36373038","https://openalex.org/I4405287411","https://openalex.org/I58956616"]},{"raw_affiliation_string":"Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I36373038","https://openalex.org/I4405287411","https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108469977","display_name":"Martha K. Cathcart","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I36373038","display_name":"Cleveland Clinic Lerner College of Medicine","ror":"https://ror.org/02x4b0932","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750","https://openalex.org/I36373038"]},{"id":"https://openalex.org/I4405287411","display_name":"Cleveland Clinic Research","ror":"https://ror.org/053229s83","country_code":"US","type":"facility","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martha K. Cathcart","raw_affiliation_strings":["the Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195, and","Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195, and","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I36373038","https://openalex.org/I4405287411","https://openalex.org/I58956616"]},{"raw_affiliation_string":"Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio 44195","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I36373038","https://openalex.org/I4405287411","https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048923192","display_name":"Manjari Kundu","orcid":"https://orcid.org/0009-0004-8458-8303","observed_orcids":["https://orcid.org/0009-0004-8458-8303"]},"institutions":[{"id":"https://openalex.org/I152754861","display_name":"Bose Institute","ror":"https://ror.org/01a5mqy88","country_code":"IN","type":"facility","lineage":["https://openalex.org/I152754861"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Manjari Kundu","raw_affiliation_strings":["the Division of Molecular Medicine, Bose Institute, Kolkata 700054, West Bengal, India","Division of Molecular Medicine, Bose Institute, Kolkata 700054, West Bengal, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Division of Molecular Medicine, Bose Institute, Kolkata 700054, West Bengal, India","institution_ids":["https://openalex.org/I152754861"]},{"raw_affiliation_string":"Division of Molecular Medicine, Bose Institute, Kolkata 700054, West Bengal, India","institution_ids":["https://openalex.org/I152754861"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015756618","display_name":"Kaushik Biswas","orcid":"https://orcid.org/0000-0003-2502-9515","observed_orcids":["https://orcid.org/0000-0003-2502-9515"]},"institutions":[{"id":"https://openalex.org/I152754861","display_name":"Bose Institute","ror":"https://ror.org/01a5mqy88","country_code":"IN","type":"facility","lineage":["https://openalex.org/I152754861"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Kaushik Biswas","raw_affiliation_strings":["the Division of Molecular Medicine, Bose Institute, Kolkata 700054, West Bengal, India","Division of Molecular Medicine, Bose Institute, Kolkata 700054, West Bengal, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Division of Molecular Medicine, Bose Institute, Kolkata 700054, West Bengal, India","institution_ids":["https://openalex.org/I152754861"]},{"raw_affiliation_string":"Division of Molecular Medicine, Bose Institute, Kolkata 700054, West Bengal, India","institution_ids":["https://openalex.org/I152754861"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101492728","display_name":"Ashish Bhattacharjee","orcid":"https://orcid.org/0000-0001-8074-6635","observed_orcids":["https://orcid.org/0000-0001-8074-6635"]},"institutions":[{"id":"https://openalex.org/I155837530","display_name":"National Institute of Technology Durgapur","ror":"https://ror.org/04ds0jm32","country_code":"IN","type":"education","lineage":["https://openalex.org/I155837530"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Ashish Bhattacharjee","raw_affiliation_strings":["From the Department of Biotechnology, National Institute of Technology-Durgapur, Mahatma Gandhi Avenue, Durgapur-713209, Burdwan, West Bengal, India, ashish15lo@yahoo.com","From the Department of Biotechnology, National Institute of Technology-Durgapur, Mahatma Gandhi Avenue, Durgapur-713209, Burdwan, West Bengal, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Biotechnology, National Institute of Technology-Durgapur, Mahatma Gandhi Avenue, Durgapur-713209, Burdwan, West Bengal, India, ashish15lo@yahoo.com","institution_ids":["https://openalex.org/I155837530"]},{"raw_affiliation_string":"From the Department of Biotechnology, National Institute of Technology-Durgapur, Mahatma Gandhi Avenue, Durgapur-713209, Burdwan, West Bengal, India","institution_ids":["https://openalex.org/I155837530"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5101492728"],"corresponding_institution_ids":["https://openalex.org/I155837530"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":1.8679,"has_fulltext":false,"cited_by_count":50,"citation_normalized_percentile":{"value":0.84961551,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"293","issue":"36","first_page":"14040","last_page":"14064"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.7993000149726868,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.7993000149726868,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.033799998462200165,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.020400000736117363,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/monoamine-oxidase-a","display_name":"monoamine oxidase A","score":1.0},{"id":"https://openalex.org/keywords/il-13","display_name":"IL-13","score":0.8920000195503235},{"id":"https://openalex.org/keywords/15-lipoxygenase","display_name":"15-lipoxygenase","score":0.9679999947547913},{"id":"https://openalex.org/keywords/monocytes","display_name":"monocytes","score":0.8190000057220459},{"id":"https://openalex.org/keywords/a549-lung-carcinoma-cells","display_name":"A549 lung carcinoma cells","score":0.9399999976158142},{"id":"https://openalex.org/keywords/stat6","display_name":"STAT6","score":0.8939999938011169},{"id":"https://openalex.org/keywords/ppargamma","display_name":"PPAR\u03b3","score":0.9169999957084656},{"id":"https://openalex.org/keywords/stat1","display_name":"STAT1","score":0.8640000224113464},{"id":"https://openalex.org/keywords/stat3","display_name":"STAT3","score":0.9950000047683716},{"id":"https://openalex.org/keywords/egr1","display_name":"EGR1","score":0.9539999961853027},{"id":"https://openalex.org/keywords/creb","display_name":"CREB","score":0.9990000128746033},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.8939999938011169},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9229999780654907},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.9549999833106995},{"id":"https://openalex.org/keywords/resolution-of-inflammation","display_name":"inflammation resolution","score":0.7210000157356262},{"id":"https://openalex.org/keywords/lung-cancer-metastasis","display_name":"lung cancer metastasis","score":0.7699999809265137},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.5550000071525574}],"concepts":[{"id":"https://openalex.org/C145430368","wikidata":"https://www.wikidata.org/wiki/Q14914613","display_name":"STAT6","level":4,"score":0.7404137849807739},{"id":"https://openalex.org/C171958077","wikidata":"https://www.wikidata.org/wiki/Q419333","display_name":"STAT protein","level":4,"score":0.6585841178894043},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5905264616012573},{"id":"https://openalex.org/C81729549","wikidata":"https://www.wikidata.org/wiki/Q4649475","display_name":"A549 cell","level":3,"score":0.5665462613105774},{"id":"https://openalex.org/C2777003663","wikidata":"https://www.wikidata.org/wiki/Q14912030","display_name":"STAT1","level":3,"score":0.5118100047111511},{"id":"https://openalex.org/C2778923194","wikidata":"https://www.wikidata.org/wiki/Q14912019","display_name":"STAT3","level":3,"score":0.5072083473205566},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48250389099121094},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.4536553621292114},{"id":"https://openalex.org/C187345961","wikidata":"https://www.wikidata.org/wiki/Q419629","display_name":"Peroxisome proliferator-activated receptor","level":3,"score":0.44323891401290894},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4299890995025635},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.42691975831985474},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.42437613010406494},{"id":"https://openalex.org/C2779723316","wikidata":"https://www.wikidata.org/wiki/Q6459234","display_name":"LNCaP","level":4,"score":0.41986513137817383},{"id":"https://openalex.org/C1629964","wikidata":"https://www.wikidata.org/wiki/Q106950729","display_name":"CREB","level":4,"score":0.41937926411628723},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.39358964562416077},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3364541232585907},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.29209399223327637},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2607156038284302},{"id":"https://openalex.org/C191732599","wikidata":"https://www.wikidata.org/wiki/Q14865947","display_name":"Interleukin 4","level":3,"score":0.2247479259967804},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.22398003935813904},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20413047075271606},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.1256517469882965},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.10874885320663452},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07655060291290283},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000072283","descriptor_name":"A549 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001093","descriptor_name":"Arachidonate 15-Lipoxygenase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008995","descriptor_name":"Monoamine Oxidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008995","descriptor_name":"Monoamine Oxidase","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018793","descriptor_name":"Interleukin-13","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D020298","descriptor_name":"U937 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D047495","descriptor_name":"PPAR gamma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050800","descriptor_name":"STAT6 Transcription Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1074/jbc.ra118.002321","doi":"https://doi.org/10.1074/jbc.ra118.002321","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.ra118.002321","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5685861","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6130935","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:30021838","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30021838","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6130935","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6130935/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Biol Chem","raw_type":"Text"},{"id":"pmh:oai:dc.etsu.edu:etsu-works-11485","doi":null,"is_oa":true,"landing_page_url":"https://dc.etsu.edu/etsu-works/10219","pdf_url":null,"source":{"id":"https://openalex.org/S4377196424","display_name":"Digital Commons - East Tennessee State University (East Tennessee State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I119443389","host_organization_name":"East Tennessee State University","host_organization_lineage":["https://openalex.org/I119443389"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ETSU Faculty Works","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1074/jbc.ra118.002321","doi":"https://doi.org/10.1074/jbc.ra118.002321","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.ra118.002321","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7231347632","display_name":null,"funder_award_id":"SERB/SR/SO/HS-093/2013","funder_id":"https://openalex.org/F4320334771","funder_display_name":"Science and Engineering Research Board"}],"funders":[{"id":"https://openalex.org/F4320320717","display_name":"Department of Biotechnology, Ministry of Science and Technology, India","ror":"https://ror.org/03tjsyq23"},{"id":"https://openalex.org/F4320334771","display_name":"Science and Engineering Research Board","ror":"https://ror.org/03ffdsr55"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":74,"referenced_works":["https://openalex.org/W156099876","https://openalex.org/W208882655","https://openalex.org/W1486057264","https://openalex.org/W1504779009","https://openalex.org/W1512525754","https://openalex.org/W1521799099","https://openalex.org/W1557523315","https://openalex.org/W1570028076","https://openalex.org/W1755295540","https://openalex.org/W1882267901","https://openalex.org/W1923917571","https://openalex.org/W1934005176","https://openalex.org/W1979859269","https://openalex.org/W1979914846","https://openalex.org/W1989123782","https://openalex.org/W1998360317","https://openalex.org/W2000158828","https://openalex.org/W2006185943","https://openalex.org/W2008057379","https://openalex.org/W2008479676","https://openalex.org/W2009170266","https://openalex.org/W2012047843","https://openalex.org/W2016868307","https://openalex.org/W2030454108","https://openalex.org/W2034108574","https://openalex.org/W2038689279","https://openalex.org/W2043956489","https://openalex.org/W2049853470","https://openalex.org/W2054472394","https://openalex.org/W2065210647","https://openalex.org/W2065357753","https://openalex.org/W2066699861","https://openalex.org/W2067674980","https://openalex.org/W2069885091","https://openalex.org/W2087647782","https://openalex.org/W2087852280","https://openalex.org/W2093705034","https://openalex.org/W2093756365","https://openalex.org/W2097906078","https://openalex.org/W2101951807","https://openalex.org/W2103010344","https://openalex.org/W2103685679","https://openalex.org/W2104378716","https://openalex.org/W2107760385","https://openalex.org/W2113125109","https://openalex.org/W2113426791","https://openalex.org/W2118382770","https://openalex.org/W2123227507","https://openalex.org/W2127641390","https://openalex.org/W2128518753","https://openalex.org/W2128964111","https://openalex.org/W2129217778","https://openalex.org/W2132306888","https://openalex.org/W2138238091","https://openalex.org/W2138567940","https://openalex.org/W2139002144","https://openalex.org/W2142606139","https://openalex.org/W2145624846","https://openalex.org/W2152309980","https://openalex.org/W2154478876","https://openalex.org/W2156933633","https://openalex.org/W2157677688","https://openalex.org/W2162327400","https://openalex.org/W2162352961","https://openalex.org/W2167485774","https://openalex.org/W2215652008","https://openalex.org/W2226281711","https://openalex.org/W2401552117","https://openalex.org/W2511728014","https://openalex.org/W2595857857","https://openalex.org/W2607224988","https://openalex.org/W2951679156","https://openalex.org/W6608439663","https://openalex.org/W6688634046"],"related_works":["https://openalex.org/W2215652008","https://openalex.org/W1557523315","https://openalex.org/W1521799099","https://openalex.org/W2008479676","https://openalex.org/W2132306888","https://openalex.org/W2270424427","https://openalex.org/W2142606139","https://openalex.org/W1820035495","https://openalex.org/W2008057379","https://openalex.org/W2129217778"],"abstract_inverted_index":{"Monoamine":[0],"oxidase":[1],"A":[2],"(MAO-A)":[3],"is":[4,58,180,216],"a":[5,28,199],"mitochondrial":[6],"flavoenzyme":[7],"implicated":[8],"in":[9,18,32,43,63,126,131,155,169,174,177,202,250],"the":[10,36,113,163,204,213,238],"pathogenesis":[11],"of":[12,93,151,167,194,207,240],"atherosclerosis":[13],"and":[14,16,70,84,91,97,101,108,130,138,149,176,188,192,222,226,242],"inflammation":[15,241],"also":[17,23],"many":[19],"neurological":[20],"disorders.":[21],"MAO-A":[22,41,56,81,135,152,168,219,245],"has":[24],"been":[25],"reported":[26],"as":[27],"potential":[29,249],"therapeutic":[30],"target":[31],"prostate":[33],"cancer.":[34],"However,":[35],"regulatory":[37],"mechanisms":[38],"controlling":[39],"cytokine-induced":[40],"expression":[42,57,83,148],"immune":[44],"or":[45],"cancer":[46,252],"cells":[47,179],"remain":[48],"to":[49,171],"be":[50],"identified.":[51],"Here,":[52],"we":[53,160],"show":[54],"that":[55,80,117,125,162,189,212,244],"co-induced":[59],"with":[60],"15-lipoxygenase":[61],"(15-LO)":[62],"interleukin":[64],"13":[65],"(IL-13)-activated":[66],"primary":[67,128],"human":[68],"monocytes":[69,129,175],"A549":[71,132,178],"non-small":[72],"cell":[73],"lung":[74,251],"carcinoma":[75],"cells.":[76,158,253],"We":[77,122,209],"present":[78],"evidence":[79],"gene":[82],"activity":[85,150,206],"are":[86,140],"regulated":[87],"by":[88,143,182],"signal":[89,190],"transducer":[90,191],"activator":[92,193],"transcription":[94,115,195],"1,":[95],"3,":[96],"6":[98,196],"(STAT1,":[99],"STAT3,":[100],"STAT6),":[102],"early":[103],"growth":[104],"response":[105,170],"1":[106],"(EGR1),":[107],"cAMP-responsive":[109],"element\u2013binding":[110],"protein":[111],"(CREB),":[112],"same":[114],"factors":[116],"control":[118],"IL-13\u2013dependent":[119],"15-LO":[120],"expression.":[121],"further":[123,210],"established":[124],"both":[127],"cells,":[133],"IL-13\u2013stimulated":[134],"expression,":[136,220],"activity,":[137,221],"function":[139],"directly":[141],"governed":[142],"15-LO.":[144],"In":[145],"contrast,":[146],"IL-13\u2013driven":[147],"was":[153],"15-LO\u2013independent":[154],"U937":[156],"promonocytic":[157],"Furthermore,":[159],"demonstrate":[161],"15-LO\u2013dependent":[164],"transcriptional":[165,205],"regulation":[166],"IL-13":[172],"stimulation":[173],"mediated":[181],"peroxisome":[183],"proliferator\u2013activated":[184],"receptor":[185],"\u03b3":[186],"(PPAR\u03b3)":[187],"(STAT6)":[197],"plays":[198],"crucial":[200],"role":[201],"facilitating":[203],"PPAR\u03b3.":[208],"report":[211],"IL-13\u2013STAT6\u201315-LO\u2013PPAR\u03b3":[214],"axis":[215],"critical":[217],"for":[218,237],"function,":[223],"including":[224],"migration":[225],"reactive":[227],"oxygen":[228],"species":[229],"generation.":[230],"Altogether,":[231],"these":[232],"results":[233],"have":[234],"major":[235],"implications":[236],"resolution":[239],"indicate":[243],"may":[246],"promote":[247],"metastatic":[248]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":8}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-08-03T00:00:00"}
