{"id":"https://openalex.org/W2883985253","doi":"https://doi.org/10.1093/jac/dky270","title":"Trends in antifungal use in US hospitals, 2006\u201312","display_name":"Trends in antifungal use in US hospitals, 2006\u201312","publication_year":2018,"publication_date":"2018-06-25","ids":{"openalex":"https://openalex.org/W2883985253","doi":"https://doi.org/10.1093/jac/dky270","mag":"2883985253","pmid":"https://pubmed.ncbi.nlm.nih.gov/30295769"},"language":"en","primary_location":{"id":"doi:10.1093/jac/dky270","doi":"https://doi.org/10.1093/jac/dky270","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jac/dky270","pdf_url":"https://academic.oup.com/jac/article-pdf/73/10/2867/25770492/dky270.pdf","source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/jac/article-pdf/73/10/2867/25770492/dky270.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072347654","display_name":"Snigdha Vallabhaneni","orcid":"https://orcid.org/0000-0003-4149-9840","observed_orcids":["https://orcid.org/0000-0003-4149-9840"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Snigdha Vallabhaneni","raw_affiliation_strings":["Mycotic Diseases Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, USA","institution_ids":["https://openalex.org/I1289490764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017654848","display_name":"James M. Baggs","orcid":"https://orcid.org/0000-0003-0757-4683","observed_orcids":["https://orcid.org/0000-0003-0757-4683"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Baggs","raw_affiliation_strings":["Division of Healthcare Quality and Promotion, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Healthcare Quality and Promotion, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, USA","institution_ids":["https://openalex.org/I1289490764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060997779","display_name":"Sharon V. Tsay","orcid":"https://orcid.org/0000-0001-9756-0896","observed_orcids":["https://orcid.org/0000-0001-9756-0896"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]},{"id":"https://openalex.org/I4210130616","display_name":"Epidemic Intelligence Service","ror":"https://ror.org/03v64vs34","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934","https://openalex.org/I4210130616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sharon Tsay","raw_affiliation_strings":["Epidemic Intelligence Service, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, USA","Mycotic Diseases Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemic Intelligence Service, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, USA","institution_ids":["https://openalex.org/I1289490764","https://openalex.org/I4210130616"]},{"raw_affiliation_string":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, USA","institution_ids":["https://openalex.org/I1289490764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103061228","display_name":"Arjun Srinivasan","orcid":"https://orcid.org/0000-0002-9529-5344","observed_orcids":["https://orcid.org/0000-0002-9529-5344"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arjun R Srinivasan","raw_affiliation_strings":["Division of Healthcare Quality and Promotion, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Healthcare Quality and Promotion, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, USA","institution_ids":["https://openalex.org/I1289490764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036433591","display_name":"John A. Jernigan","orcid":"https://orcid.org/0000-0001-8163-925X","observed_orcids":["https://orcid.org/0000-0001-8163-925X"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John A Jernigan","raw_affiliation_strings":["Division of Healthcare Quality and Promotion, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Healthcare Quality and Promotion, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, USA","institution_ids":["https://openalex.org/I1289490764"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010760444","display_name":"Brendan R. Jackson","orcid":"https://orcid.org/0000-0002-3369-2408","observed_orcids":["https://orcid.org/0000-0002-3369-2408"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brendan R Jackson","raw_affiliation_strings":["Mycotic Diseases Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA, USA","institution_ids":["https://openalex.org/I1289490764"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5072347654"],"corresponding_institution_ids":["https://openalex.org/I1289490764"],"apc_list":{"value":2869,"currency":"GBP","value_usd":3784},"apc_paid":{"value":2869,"currency":"GBP","value_usd":3784},"fwci":4.7716,"has_fulltext":true,"cited_by_count":46,"citation_normalized_percentile":{"value":0.95973086,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"73","issue":"10","first_page":"2867","last_page":"2875"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.013500000350177288,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antifungal-stewardship","display_name":"antifungal stewardship","score":0.7749999761581421},{"id":"https://openalex.org/keywords/days-of-therapy","display_name":"days of therapy","score":0.7360000014305115},{"id":"https://openalex.org/keywords/azoles","display_name":"azoles","score":0.6269999742507935},{"id":"https://openalex.org/keywords/echinocandins","display_name":"echinocandins","score":0.9409999847412109},{"id":"https://openalex.org/keywords/polyenes","display_name":"polyenes","score":0.9409999847412109},{"id":"https://openalex.org/keywords/fluconazole","display_name":"fluconazole","score":0.9229999780654907},{"id":"https://openalex.org/keywords/intensive-care-unit","display_name":"intensive care unit","score":0.8560000061988831},{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.6880000233650208},{"id":"https://openalex.org/keywords/hiv","display_name":"HIV","score":0.9369999766349792},{"id":"https://openalex.org/keywords/antineoplastic-therapy","display_name":"antineoplastic therapy","score":0.9559999704360962},{"id":"https://openalex.org/keywords/antimicrobial-resistance","display_name":"antimicrobial resistance","score":0.7160000205039978},{"id":"https://openalex.org/keywords/prescribing-trends","display_name":"prescribing trends","score":0.44200000166893005}],"concepts":[{"id":"https://openalex.org/C2910751997","wikidata":"https://www.wikidata.org/wiki/Q3718510","display_name":"Echinocandins","level":5,"score":0.8394761085510254},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.693989634513855},{"id":"https://openalex.org/C2780651595","wikidata":"https://www.wikidata.org/wiki/Q411478","display_name":"Fluconazole","level":3,"score":0.6505162715911865},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.6397261619567871},{"id":"https://openalex.org/C2779320740","wikidata":"https://www.wikidata.org/wiki/Q3718510","display_name":"Echinocandin","level":4,"score":0.519564151763916},{"id":"https://openalex.org/C2991737395","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal drug","level":3,"score":0.5070407390594482},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.49368390440940857},{"id":"https://openalex.org/C2776534028","wikidata":"https://www.wikidata.org/wiki/Q1141363","display_name":"Medicaid","level":3,"score":0.4868830740451813},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39901256561279297},{"id":"https://openalex.org/C2780402444","wikidata":"https://www.wikidata.org/wiki/Q420875","display_name":"Caspofungin","level":4,"score":0.22277477383613586},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.16967695951461792},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.0},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001393","descriptor_name":"Azoles","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D004363","descriptor_name":"Drug Utilization","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D006761","descriptor_name":"Hospitals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007297","descriptor_name":"Inpatients","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011090","descriptor_name":"Polyenes","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054714","descriptor_name":"Echinocandins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/jac/dky270","doi":"https://doi.org/10.1093/jac/dky270","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jac/dky270","pdf_url":"https://academic.oup.com/jac/article-pdf/73/10/2867/25770492/dky270.pdf","source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},{"id":"pmid:30295769","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30295769","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of antimicrobial chemotherapy","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1093/jac/dky270","doi":"https://doi.org/10.1093/jac/dky270","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jac/dky270","pdf_url":"https://academic.oup.com/jac/article-pdf/73/10/2867/25770492/dky270.pdf","source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9789000153541565,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2883985253.pdf","grobid_xml":"https://content.openalex.org/works/W2883985253.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W5362396","https://openalex.org/W1594888675","https://openalex.org/W1796131488","https://openalex.org/W1879723880","https://openalex.org/W1975135469","https://openalex.org/W1981422213","https://openalex.org/W1989319949","https://openalex.org/W2022509003","https://openalex.org/W2044502735","https://openalex.org/W2058502661","https://openalex.org/W2087018232","https://openalex.org/W2090465492","https://openalex.org/W2098462635","https://openalex.org/W2110486614","https://openalex.org/W2114954734","https://openalex.org/W2115835722","https://openalex.org/W2119441966","https://openalex.org/W2122173144","https://openalex.org/W2123134253","https://openalex.org/W2124994452","https://openalex.org/W2130219862","https://openalex.org/W2132117678","https://openalex.org/W2137575148","https://openalex.org/W2145771625","https://openalex.org/W2147069968","https://openalex.org/W2150428940","https://openalex.org/W2151868700","https://openalex.org/W2164990391","https://openalex.org/W2170063898","https://openalex.org/W2198459591","https://openalex.org/W2216117396","https://openalex.org/W2276873560","https://openalex.org/W2285437942","https://openalex.org/W2286158356","https://openalex.org/W2330223144","https://openalex.org/W2523533059","https://openalex.org/W2577939788","https://openalex.org/W2625201664","https://openalex.org/W2766020969"],"related_works":["https://openalex.org/W2561701307","https://openalex.org/W4200326899","https://openalex.org/W4413112946","https://openalex.org/W2333674004","https://openalex.org/W2288422827","https://openalex.org/W2982750020","https://openalex.org/W2922595912","https://openalex.org/W2886832919","https://openalex.org/W4407854313","https://openalex.org/W4396625751"],"abstract_inverted_index":{"Background:":[0],"Although":[1],"trends":[2,38,107],"in":[3,39,43,120,207,232],"antibiotic":[4],"use":[5,18,42,148],"have":[6,226],"been":[7],"characterized,":[8],"less":[9],"is":[10],"known":[11],"about":[12],"antifungal":[13,17,28,32,41,82,130,147,220,246],"use.":[14,221],"Data":[15],"on":[16,243],"are":[19],"important":[20],"for":[21,50,99,128,133,138,143,162,196,213,248],"understanding":[22],"practice":[23],"patterns,":[24],"assessing":[25],"emergence":[26],"of":[27,66,75,113,118,145,219],"resistance":[29],"and":[30,73,87,101,105,116,136,165,171,179,186,210,240,242],"developing":[31],"stewardship":[33,223],"programmes.":[34],"We":[35,90],"estimated":[36,63,125],"national":[37,92],"inpatient":[40],"the":[44,53,64,191,227],"USA.":[45],"Methods:":[46],"Using":[47],"billing":[48],"data":[49,104],"antifungals":[51,70],"from":[52,97],"Truven":[54],"Health":[55],"MarketScan\u00ae":[56],"Hospital":[57],"Drug":[58],"Database":[59],"during":[60,177],"2006-12,":[61],"we":[62],"proportion":[65,218],"discharges":[67],"at":[68],"which":[69],"were":[71,189,203],"given":[72],"days":[74,79],"therapy":[76,188,247],"(DOT)/1000":[77],"patient":[78,86,236],"(PDs)":[80],"by":[81,152],"drug":[83],"type,":[84],"year,":[85],"facility":[88],"characteristics.":[89],"created":[91],"estimates":[93],"using":[94],"weights":[95],"generated":[96],"Centers":[98],"Medicare":[100],"Medicaid":[102],"Services":[103],"assessed":[106],"over":[108],"time.":[109],"Results:":[110],"Overall,":[111],"2.7%":[112],"all":[114,134,146],"inpatients":[115,135],"7.7%":[117],"those":[119],"ICUs":[121],"received":[122,199],"antifungals.":[123,200],"The":[124],"DOT/1000":[126,160],"PDs":[127,161],"any":[129],"was":[131],"35.0":[132],"73.7":[137],"ICU":[139,208],"patients.":[140],"Azoles":[141],"accounted":[142,212],"80%":[144],"(28.5/1000":[149],"PDs),":[150],"followed":[151],"echinocandins":[153,174],"(5.0/1000":[154],"PDs).":[155],"By":[156],"multivariable":[157],"trend":[158],"analysis,":[159],"azoles":[163],"(-21%)":[164],"polyenes":[166],"(-47%)":[167],"decreased":[168],"between":[169],"2006":[170],"2012,":[172],"whereas":[173],"increased":[175],"11%":[176],"2006-10":[178],"declined":[180],"after":[181],"2011.":[182],"Unspecified":[183],"septicaemia,":[184],"HIV":[185,239],"antineoplastic":[187],"among":[190,234],"top":[192],"primary":[193],"diagnosis":[194],"codes":[195],"patients":[197],"who":[198],"Conclusions:":[201],"Antifungals":[202],"most":[204,228],"frequently":[205],"used":[206],"settings":[209],"fluconazole":[211],"a":[214],"large,":[215],"but":[216],"declining,":[217],"Antifungal":[222],"efforts":[224],"may":[225],"impact":[229],"if":[230],"focused":[231],"ICUs,":[233],"certain":[235],"groups":[237],"(e.g.":[238],"malignancy)":[241],"stopping":[244],"empirical":[245],"unspecified":[249],"sepsis":[250],"when":[251],"not":[252],"indicated.":[253]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-08-03T00:00:00"}