{"id":"https://openalex.org/W2883973528","doi":null,"title":"Real-World Efficacy and Tolerability of Heme Iron Polypeptide in Non-Pregnant and Pregnant Women with Iron Deficiency Anemia","display_name":"Real-World Efficacy and Tolerability of Heme Iron Polypeptide in Non-Pregnant and Pregnant Women with Iron Deficiency Anemia","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2883973528","mag":"2883973528"},"language":"en","primary_location":{"id":"mag:2883973528","doi":null,"is_oa":false,"landing_page_url":"https://www.ijmrhs.com/abstract/realworld-efficacy-and-tolerability-of-heme-iron-polypeptide-in-nonpregnant-and-pregnant-women-with-iron-deficiency-anem-15089.html","pdf_url":null,"source":{"id":"https://openalex.org/S2737401022","display_name":"International Journal of Medical Research & Health Sciences","issn_l":"2319-5886","issn":["2319-5886"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4310318747","host_organization_name":"Sumathi Publications","host_organization_lineage":["https://openalex.org/P4310318747"],"host_organization_lineage_names":["Sumathi Publications"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Medical Research & Health Sciences","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111875647","display_name":"Varsha Narayanan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Varsha Narayanan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"Amit Bhargava","orcid":"https://orcid.org/0000-0003-4586-8340","observed_orcids":["https://orcid.org/0000-0003-4586-8340"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amit Bhargava","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4586-8340","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1825,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.53593799,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"7","issue":"6","first_page":"50","last_page":"56"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/iron-deficiency-anemia","display_name":"iron deficiency anemia","score":0.9900000095367432},{"id":"https://openalex.org/keywords/oral-iron-supplementation","display_name":"oral iron supplementation","score":0.8759999871253967},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.7379999756813049},{"id":"https://openalex.org/keywords/nonpregnant-women","display_name":"non-pregnant women","score":0.8690000176429749},{"id":"https://openalex.org/keywords/hemoglobin-response","display_name":"hemoglobin response","score":0.8109999895095825},{"id":"https://openalex.org/keywords/ferritin","display_name":"ferritin","score":0.796999990940094},{"id":"https://openalex.org/keywords/gastrointestinal-tolerability","display_name":"gastrointestinal tolerance","score":0.878000020980835},{"id":"https://openalex.org/keywords/real-world-effectiveness","display_name":"real-world effectiveness","score":0.4359999895095825},{"id":"https://openalex.org/keywords/anemia-in-pregnancy","display_name":"anemia in pregnancy","score":0.5260000228881836}],"concepts":[{"id":"https://openalex.org/C2778375690","wikidata":"https://www.wikidata.org/wiki/Q7814214","display_name":"Tolerability","level":3,"score":0.9515699148178101},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8622202277183533},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.7388148307800293},{"id":"https://openalex.org/C2777417653","wikidata":"https://www.wikidata.org/wiki/Q1313081","display_name":"Iron deficiency","level":3,"score":0.6220602989196777},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.5940987467765808},{"id":"https://openalex.org/C2776732101","wikidata":"https://www.wikidata.org/wiki/Q954674","display_name":"Iron-deficiency anemia","level":3,"score":0.5139174461364746},{"id":"https://openalex.org/C2778319317","wikidata":"https://www.wikidata.org/wiki/Q22327449","display_name":"Ferritin","level":2,"score":0.5079987645149231},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.46928510069847107},{"id":"https://openalex.org/C2780959883","wikidata":"https://www.wikidata.org/wiki/Q111146","display_name":"Hematocrit","level":2,"score":0.42511314153671265},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4009873569011688},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3796851634979248},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.3669416904449463},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.17651334404945374},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2883973528","doi":null,"is_oa":false,"landing_page_url":"https://www.ijmrhs.com/abstract/realworld-efficacy-and-tolerability-of-heme-iron-polypeptide-in-nonpregnant-and-pregnant-women-with-iron-deficiency-anem-15089.html","pdf_url":null,"source":{"id":"https://openalex.org/S2737401022","display_name":"International Journal of Medical Research & Health Sciences","issn_l":"2319-5886","issn":["2319-5886"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4310318747","host_organization_name":"Sumathi Publications","host_organization_lineage":["https://openalex.org/P4310318747"],"host_organization_lineage_names":["Sumathi Publications"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Medical Research & Health Sciences","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"},{"display_name":"Zero hunger","score":0.5365999937057495,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1533110363","https://openalex.org/W1547731352","https://openalex.org/W1608839794","https://openalex.org/W1636938975","https://openalex.org/W1863616792","https://openalex.org/W1991448658","https://openalex.org/W2022159213","https://openalex.org/W2030229873","https://openalex.org/W2054656670","https://openalex.org/W2057284672","https://openalex.org/W2065498595","https://openalex.org/W2096053912","https://openalex.org/W2109211075","https://openalex.org/W2116113041","https://openalex.org/W2144001894","https://openalex.org/W2162858536","https://openalex.org/W2588503423"],"related_works":["https://openalex.org/W2906997050","https://openalex.org/W7130517334","https://openalex.org/W3016183543","https://openalex.org/W2606146620","https://openalex.org/W3120080432","https://openalex.org/W7208824542","https://openalex.org/W2156169191","https://openalex.org/W4407820256","https://openalex.org/W2892753101","https://openalex.org/W7160954980"],"abstract_inverted_index":{"Background:":[0],"Iron":[1],"deficiency":[2,120,305],"anemia":[3,121],"is":[4,100],"a":[5,63,240,273],"common":[6],"condition":[7],"affecting":[8],"the":[9,30,165,177,201,244],"quality":[10],"of":[11,36,76,118,127,141,150,246,268,280],"life,":[12],"as":[13,15,253,255],"well":[14,254],"maternal":[16],"and":[17,22,33,52,56,66,79,97,105,134,164,185,194,207,215,228,234,250,263,300,312],"fetal":[18],"outcomes":[19],"in":[20,95,180,188,198,210,220,225,243,256,298,314],"non-pregnant":[21,98,104,175,229,301],"pregnant":[23,96,106,199,227,299],"women":[24,107,230,302],"respectively.":[25],"Oral":[26,58],"iron":[27,40,60,72,119,143,304],"supplementation":[28,61],"represents":[29,62],"most":[31],"convenient":[32],"cost-effective":[34],"form":[35],"therapy.":[37,73],"Conventional":[38],"non-heme":[39],"oral":[41,71,289],"supplements":[42],"are":[43,81],"known":[44],"to":[45,168,307],"be":[46,293],"associated":[47],"with":[48,114,131,138,190,212,231,248,259,272,303],"poor":[49],"gastrointestinal":[50,310],"tolerability,":[51],"therefore":[53],"reduced":[54],"compliance":[55],"efficacy.":[57],"Heme":[59],"better":[64,309],"tolerated":[65],"more":[67],"bioavailable":[68],"option":[69,297],"for":[70,146],"Though":[74],"evidence":[75],"its":[77,92,308],"efficacy":[78,313],"tolerability":[80,167,267,311],"available":[82],"through":[83],"some":[84],"randomized":[85],"clinical":[86],"trials,":[87],"real":[88],"world":[89],"data":[90],"from":[91],"regular":[93],"use":[94],"patients":[99,247,258],"lacking.":[101],"Methodology:":[102],"378":[103],"visiting":[108],"56":[109],"gynecology":[110],"clinics":[111],"across":[112],"India":[113],"an":[115,147,294],"in-clinic":[116],"diagnosis":[117],"based":[122],"on":[123],"baseline":[124,157,191,213,232],"laboratory":[125],"evaluation":[126],"hemoglobin":[128],"(Hb),":[129],"along":[130],"ferritin,":[132,261],"MCV":[133,262],"hematocrit,":[135],"were":[136,158],"treated":[137],"daily":[139],"tablets":[140],"heme":[142],"polypeptide":[144],"(HIP)":[145],"average":[148,178,202],"duration":[149],"3":[151],"months.":[152],"Laboratory":[153],"parameters":[154],"assessed":[155],"at":[156,160],"repeated":[159],"final":[161],"follow":[162],"up":[163],"patients\u2019":[166],"therapy":[169,291],"was":[170,182,205,222,238,270],"also":[171,239],"recorded.":[172],"Results:":[173],"In":[174],"women,":[176,200],"rise":[179,204,219],"Hb":[181,203,221],"1.17,":[183],"2.06":[184],"3.28":[186],"(g/dl),":[187],"groups":[189,211],"mild,":[192],"moderate,":[193],"severe":[195,216,235,251],"anemia,":[196,252],"while":[197],"2.70":[206],"3.53":[208],"(g/dl)":[209],"moderate":[214,233,249],"anemia.":[217,236],"The":[218,266],"highly":[223],"significant":[224,241],"both":[226],"There":[237],"decline":[242],"number":[245],"percentage":[257],"low":[260],"hematocrit":[264],"values.":[265],"HIP":[269,290],"satisfactory":[271],"treatment":[274,296],"adverse":[275],"event":[276],"related":[277],"discontinuation":[278],"rate":[279],"less":[281],"than":[282],"0.8%.":[283],"Conclusion:":[284],"This":[285],"study":[286],"suggests":[287],"that":[288],"can":[292],"effective":[295],"due":[306],"improving":[315],"hematological":[316],"parameters.":[317]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-08-03T00:00:00"}