{"id":"https://openalex.org/W2883598552","doi":"https://doi.org/10.1128/iai.00371-18","title":"PhoPR Contributes to Staphylococcus aureus Growth during Phosphate Starvation and Pathogenesis in an Environment-Specific Manner","display_name":"PhoPR Contributes to Staphylococcus aureus Growth during Phosphate Starvation and Pathogenesis in an Environment-Specific Manner","publication_year":2018,"publication_date":"2018-07-25","ids":{"openalex":"https://openalex.org/W2883598552","doi":"https://doi.org/10.1128/iai.00371-18","mag":"2883598552","pmid":"https://pubmed.ncbi.nlm.nih.gov/30061377","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6204748"},"language":"en","primary_location":{"id":"doi:10.1128/iai.00371-18","doi":"https://doi.org/10.1128/iai.00371-18","is_oa":true,"landing_page_url":"https://doi.org/10.1128/iai.00371-18","pdf_url":"https://iai.asm.org/content/iai/86/10/e00371-18.full.pdf","source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://iai.asm.org/content/iai/86/10/e00371-18.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000282172","display_name":"Jessica L. Kelliher","orcid":"https://orcid.org/0000-0001-7875-3158","observed_orcids":["https://orcid.org/0000-0001-7875-3158","https://orcid.org/0000-0001-7734-8337"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessica L. Kelliher","raw_affiliation_strings":["Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063776850","display_name":"Jana N. Radin","orcid":"https://orcid.org/0000-0003-1783-7336","observed_orcids":["https://orcid.org/0000-0003-1783-7336"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jana N. Radin","raw_affiliation_strings":["Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056626099","display_name":"Thomas E. Kehl\u2010Fie","orcid":"https://orcid.org/0000-0001-8234-1113","observed_orcids":["https://orcid.org/0000-0001-8234-1113"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I4405271866","display_name":"Carl R. Woese Institute for Genomic Biology","ror":"https://ror.org/036j6yj81","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405271866"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas E. Kehl-Fie","raw_affiliation_strings":["Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA","Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I4405271866"]},{"raw_affiliation_string":"Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA","institution_ids":["https://openalex.org/I157725225"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.5724,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.82915882,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"86","issue":"10","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.8769999742507935,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.8769999742507935,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.09700000286102295,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9990000128746033},{"id":"https://openalex.org/keywords/phosphate-starvation","display_name":"phosphate limitation","score":0.9940000176429749},{"id":"https://openalex.org/keywords/phosphate-acquisition","display_name":"phosphate acquisition","score":0.9710000157356262},{"id":"https://openalex.org/keywords/bacterial-growth","display_name":"bacterial growth","score":0.8579999804496765},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.7749999761581421},{"id":"https://openalex.org/keywords/environmental-adaptation","display_name":"environmental adaptation","score":0.699999988079071},{"id":"https://openalex.org/keywords/host-pathogen-interaction","display_name":"host-pathogen interaction","score":0.6790000200271606}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.811972975730896},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.7405318021774292},{"id":"https://openalex.org/C2777132085","wikidata":"https://www.wikidata.org/wiki/Q46220103","display_name":"Phosphate","level":2,"score":0.6741671562194824},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.657010555267334},{"id":"https://openalex.org/C2780606744","wikidata":"https://www.wikidata.org/wiki/Q853930","display_name":"Starvation","level":2,"score":0.6131612062454224},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6127157211303711},{"id":"https://openalex.org/C2777334864","wikidata":"https://www.wikidata.org/wiki/Q34879","display_name":"Staphylococcal infections","level":4,"score":0.5491138696670532},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.4915975034236908},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.24448788166046143},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1557084321975708},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.05729609727859497},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010710","descriptor_name":"Phosphates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013203","descriptor_name":"Staphylococcal Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D013211","descriptor_name":"Staphylococcus aureus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013211","descriptor_name":"Staphylococcus aureus","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D013211","descriptor_name":"Staphylococcus aureus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013211","descriptor_name":"Staphylococcus aureus","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015964","descriptor_name":"Gene Expression Regulation, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/iai.00371-18","doi":"https://doi.org/10.1128/iai.00371-18","is_oa":true,"landing_page_url":"https://doi.org/10.1128/iai.00371-18","pdf_url":"https://iai.asm.org/content/iai/86/10/e00371-18.full.pdf","source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5408180","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6204748","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6204748","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6204748","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infect Immun","raw_type":"Text"},{"id":"pmid:30061377","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30061377","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and immunity","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1128/iai.00371-18","doi":"https://doi.org/10.1128/iai.00371-18","is_oa":true,"landing_page_url":"https://doi.org/10.1128/iai.00371-18","pdf_url":"https://iai.asm.org/content/iai/86/10/e00371-18.full.pdf","source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3274248539","display_name":null,"funder_award_id":"5-FY15-30","funder_id":"https://openalex.org/F4320306182","funder_display_name":"March of Dimes Foundation"},{"id":"https://openalex.org/G7930144872","display_name":"Overcoming nutritional immunity: Staphylococcal adaptation to host-imposed manganese and zinc starvation","funder_award_id":"R01AI118880","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8979134418","display_name":"Adaptation of Staphylococcus aureus to Mn and Zn starvation imposed by the host","funder_award_id":"K22AI104805","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320306182","display_name":"March of Dimes Foundation","ror":"https://ror.org/04bd5p711"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2883598552.pdf"},"referenced_works_count":71,"referenced_works":["https://openalex.org/W77167132","https://openalex.org/W184263843","https://openalex.org/W1512810258","https://openalex.org/W1547119536","https://openalex.org/W1601371949","https://openalex.org/W1786268878","https://openalex.org/W1789315565","https://openalex.org/W1792186902","https://openalex.org/W1833844910","https://openalex.org/W1878404532","https://openalex.org/W1925784940","https://openalex.org/W1954099314","https://openalex.org/W1966669851","https://openalex.org/W1969780845","https://openalex.org/W1971023242","https://openalex.org/W1976381180","https://openalex.org/W1985259885","https://openalex.org/W1995388616","https://openalex.org/W1998673116","https://openalex.org/W2003014014","https://openalex.org/W2004986663","https://openalex.org/W2013319822","https://openalex.org/W2015081806","https://openalex.org/W2019371092","https://openalex.org/W2026116367","https://openalex.org/W2041192471","https://openalex.org/W2044666761","https://openalex.org/W2055224823","https://openalex.org/W2057427059","https://openalex.org/W2077225298","https://openalex.org/W2095875226","https://openalex.org/W2096786316","https://openalex.org/W2097578220","https://openalex.org/W2103475644","https://openalex.org/W2109817270","https://openalex.org/W2116356176","https://openalex.org/W2123180145","https://openalex.org/W2125682200","https://openalex.org/W2127113854","https://openalex.org/W2141306398","https://openalex.org/W2145568057","https://openalex.org/W2147251439","https://openalex.org/W2149540999","https://openalex.org/W2149603927","https://openalex.org/W2151150074","https://openalex.org/W2153352437","https://openalex.org/W2154133707","https://openalex.org/W2155397502","https://openalex.org/W2155505592","https://openalex.org/W2157572113","https://openalex.org/W2159177223","https://openalex.org/W2159882344","https://openalex.org/W2171498110","https://openalex.org/W2174258440","https://openalex.org/W2267880147","https://openalex.org/W2294741826","https://openalex.org/W2421070788","https://openalex.org/W2479959824","https://openalex.org/W2515445802","https://openalex.org/W2550830742","https://openalex.org/W2573968363","https://openalex.org/W2606423945","https://openalex.org/W2613567896","https://openalex.org/W2735773016","https://openalex.org/W2760399796","https://openalex.org/W2766949579","https://openalex.org/W2800733468","https://openalex.org/W3129911986","https://openalex.org/W4242318543","https://openalex.org/W4244022288","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2969572397","https://openalex.org/W7029662716","https://openalex.org/W7217458677","https://openalex.org/W2784931728","https://openalex.org/W3081994763","https://openalex.org/W7155217279","https://openalex.org/W4414164855","https://openalex.org/W4401686334","https://openalex.org/W2052580877","https://openalex.org/W4413111156"],"abstract_inverted_index":{"Microbial":[0],"pathogens":[1],"must":[2],"obtain":[3],"all":[4],"essential":[5],"nutrients,":[6],"including":[7],"phosphate,":[8],"from":[9],"the":[10,28],"host.":[11],"To":[12],"optimize":[13],"phosphate":[14],"acquisition":[15],"in":[16],"diverse":[17],"and":[18],"dynamic":[19],"environments,":[20],"such":[21],"as":[22],"mammalian":[23],"tissues,":[24],"many":[25],"bacteria":[26],"use":[27],"PhoPR":[29],"two-component":[30],"system.":[31]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-08-03T00:00:00"}