{"id":"https://openalex.org/W2883481272","doi":"https://doi.org/10.1016/j.talanta.2018.07.064","title":"A new selective fluorescence probe with a quinoxalinone structure (QP-1) for cysteine and its application in live-cell imaging","display_name":"A new selective fluorescence probe with a quinoxalinone structure (QP-1) for cysteine and its application in live-cell imaging","publication_year":2018,"publication_date":"2018-07-20","ids":{"openalex":"https://openalex.org/W2883481272","doi":"https://doi.org/10.1016/j.talanta.2018.07.064","mag":"2883481272","pmid":"https://pubmed.ncbi.nlm.nih.gov/30086969"},"language":"en","primary_location":{"id":"doi:10.1016/j.talanta.2018.07.064","doi":"https://doi.org/10.1016/j.talanta.2018.07.064","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.talanta.2018.07.064","pdf_url":null,"source":{"id":"https://openalex.org/S124795565","display_name":"Talanta","issn_l":"0039-9140","issn":["0039-9140","1873-3573"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Talanta","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101641935","display_name":"Bing Yang","orcid":"https://orcid.org/0000-0002-6342-3612","observed_orcids":["https://orcid.org/0000-0002-6342-3612"]},"institutions":[{"id":"https://openalex.org/I4391768045","display_name":"State Key Laboratory of Pharmaceutical Biotechnology","ror":"https://ror.org/043ea4m21","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bing Yang","raw_affiliation_strings":["State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067660330","display_name":"Jing Xu","orcid":"https://orcid.org/0000-0001-9946-4769","observed_orcids":["https://orcid.org/0000-0001-9946-4769"]},"institutions":[{"id":"https://openalex.org/I4391768045","display_name":"State Key Laboratory of Pharmaceutical Biotechnology","ror":"https://ror.org/043ea4m21","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Xu","raw_affiliation_strings":["State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025398732","display_name":"Zeng-Hui Yuan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4391768045","display_name":"State Key Laboratory of Pharmaceutical Biotechnology","ror":"https://ror.org/043ea4m21","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zeng-Hui Yuan","raw_affiliation_strings":["State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011332962","display_name":"Da-Jun Zheng","orcid":"https://orcid.org/0000-0003-3922-3933","observed_orcids":["https://orcid.org/0000-0003-3922-3933"]},"institutions":[{"id":"https://openalex.org/I4391768045","display_name":"State Key Laboratory of Pharmaceutical Biotechnology","ror":"https://ror.org/043ea4m21","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Da-Jun Zheng","raw_affiliation_strings":["State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090454892","display_name":"Zhenxiang He","orcid":"https://orcid.org/0009-0004-8441-9534","observed_orcids":["https://orcid.org/0009-0004-8441-9534","https://orcid.org/0009-0007-6458-6820"]},"institutions":[{"id":"https://openalex.org/I4391768045","display_name":"State Key Laboratory of Pharmaceutical Biotechnology","ror":"https://ror.org/043ea4m21","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhen-Xiang He","raw_affiliation_strings":["State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China. Electronic address: zxhe@nju.edu.cn","State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China. Electronic address: zxhe@nju.edu.cn","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"raw_affiliation_string":"State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103818197","display_name":"Qingcai Jiao","orcid":"https://orcid.org/0009-0008-3354-0667","observed_orcids":["https://orcid.org/0009-0008-3354-0667"]},"institutions":[{"id":"https://openalex.org/I4391768045","display_name":"State Key Laboratory of Pharmaceutical Biotechnology","ror":"https://ror.org/043ea4m21","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qing-Cai Jiao","raw_affiliation_strings":["State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China. Electronic address: jiaoqc@nju.edu.cn","State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China. Electronic address: jiaoqc@nju.edu.cn","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"raw_affiliation_string":"State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100376356","display_name":"Hai\u2010Liang Zhu","orcid":"https://orcid.org/0000-0003-4738-7655","observed_orcids":["https://orcid.org/0000-0003-4738-7655"]},"institutions":[{"id":"https://openalex.org/I4391768045","display_name":"State Key Laboratory of Pharmaceutical Biotechnology","ror":"https://ror.org/043ea4m21","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hai-Liang Zhu","raw_affiliation_strings":["State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China. Electronic address: zhuhl@nju.edu.cn","State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China. Electronic address: zhuhl@nju.edu.cn","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"raw_affiliation_string":"State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5090454892","https://openalex.org/A5100376356","https://openalex.org/A5103818197"],"corresponding_institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"],"apc_list":{"value":4610,"currency":"USD","value_usd":4610},"apc_paid":null,"fwci":1.1993,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.71652422,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"189","issue":null,"first_page":"629","last_page":"635"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11481","display_name":"Sulfur Compounds in Biology","score":0.9624000191688538,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11481","display_name":"Sulfur Compounds in Biology","score":0.9624000191688538,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10532","display_name":"Molecular Sensors and Ion Detection","score":0.03669999912381172,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cysteine-detection","display_name":"cysteine detection","score":0.8840000033378601},{"id":"https://openalex.org/keywords/fluorescent-probes","display_name":"fluorescent probes","score":0.8209999799728394},{"id":"https://openalex.org/keywords/quinoxalinones","display_name":"quinoxalinones","score":0.9890000224113464},{"id":"https://openalex.org/keywords/biothiols","display_name":"biothiols","score":0.7850000262260437},{"id":"https://openalex.org/keywords/live-cell-imaging","display_name":"live-cell imaging","score":0.7519999742507935},{"id":"https://openalex.org/keywords/probe-selectivity","display_name":"probe selectivity","score":0.7390000224113464}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9742535352706909},{"id":"https://openalex.org/C118792377","wikidata":"https://www.wikidata.org/wiki/Q108584245","display_name":"Selectivity","level":3,"score":0.7797456979751587},{"id":"https://openalex.org/C2779201268","wikidata":"https://www.wikidata.org/wiki/Q186474","display_name":"Cysteine","level":3,"score":0.7570481300354004},{"id":"https://openalex.org/C197336794","wikidata":"https://www.wikidata.org/wiki/Q5161150","display_name":"Conjugate","level":2,"score":0.7299085855484009},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.6264683604240417},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.5441064834594727},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.3871188461780548},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.21219965815544128},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18743851780891418},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.08543145656585693},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003545","descriptor_name":"Cysteine","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D003545","descriptor_name":"Cysteine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011810","descriptor_name":"Quinoxalines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061848","descriptor_name":"Optical Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.talanta.2018.07.064","doi":"https://doi.org/10.1016/j.talanta.2018.07.064","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.talanta.2018.07.064","pdf_url":null,"source":{"id":"https://openalex.org/S124795565","display_name":"Talanta","issn_l":"0039-9140","issn":["0039-9140","1873-3573"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Talanta","raw_type":"journal-article"},{"id":"pmid:30086969","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30086969","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Talanta","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3711877293","display_name":null,"funder_award_id":"1701127B","funder_id":"https://openalex.org/F4320335471","funder_display_name":"Jiangsu Planned Projects for Postdoctoral Research Funds"},{"id":"https://openalex.org/G698251625","display_name":null,"funder_award_id":"020814380061","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"}],"funders":[{"id":"https://openalex.org/F4320335471","display_name":"Jiangsu Planned Projects for Postdoctoral Research Funds","ror":null},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W1655177618","https://openalex.org/W1805161820","https://openalex.org/W1843436898","https://openalex.org/W1896510288","https://openalex.org/W1925461903","https://openalex.org/W1930283869","https://openalex.org/W1968095645","https://openalex.org/W1970893153","https://openalex.org/W1971289386","https://openalex.org/W1972054336","https://openalex.org/W1979599160","https://openalex.org/W1981731904","https://openalex.org/W1993301631","https://openalex.org/W1994830244","https://openalex.org/W2003659770","https://openalex.org/W2013070913","https://openalex.org/W2018339027","https://openalex.org/W2021224709","https://openalex.org/W2024422280","https://openalex.org/W2028786217","https://openalex.org/W2030015314","https://openalex.org/W2036278497","https://openalex.org/W2040349635","https://openalex.org/W2054831887","https://openalex.org/W2060992649","https://openalex.org/W2068192312","https://openalex.org/W2069143463","https://openalex.org/W2071113961","https://openalex.org/W2079709777","https://openalex.org/W2088496271","https://openalex.org/W2119817499","https://openalex.org/W2126266723","https://openalex.org/W2134369482","https://openalex.org/W2150031760","https://openalex.org/W2153733892","https://openalex.org/W2160759026","https://openalex.org/W2167534959","https://openalex.org/W2169225367","https://openalex.org/W2314762075","https://openalex.org/W2326385763","https://openalex.org/W2465959331","https://openalex.org/W2473971978","https://openalex.org/W2478478231","https://openalex.org/W2554776633","https://openalex.org/W2582212700","https://openalex.org/W2586923067","https://openalex.org/W2624773477","https://openalex.org/W2729719544","https://openalex.org/W2732337149","https://openalex.org/W2762198662","https://openalex.org/W2789901235","https://openalex.org/W2795292634"],"related_works":["https://openalex.org/W2802701373","https://openalex.org/W2908558759","https://openalex.org/W2794078867","https://openalex.org/W2946940953","https://openalex.org/W2803327888","https://openalex.org/W2925270429","https://openalex.org/W2966309900","https://openalex.org/W4387990021","https://openalex.org/W4389104350","https://openalex.org/W4408812985"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-08-03T00:00:00"}