{"id":"https://openalex.org/W2883000582","doi":null,"title":"Efekti kvercetina i epikatehina na oksidativno-antioksidativni status pacova tretiranih bakar(II)-jonom","display_name":"Efekti kvercetina i epikatehina na oksidativno-antioksidativni status pacova tretiranih bakar(II)-jonom","publication_year":2015,"publication_date":"2015-02-12","ids":{"openalex":"https://openalex.org/W2883000582","mag":"2883000582"},"language":"sr","primary_location":{"id":"pmh:oai:nardus.mpn.gov.rs:123456789/3616","doi":null,"is_oa":true,"landing_page_url":"https://nardus.mpn.gov.rs/handle/123456789/3616","pdf_url":null,"source":{"id":"https://openalex.org/S4377196110","display_name":"National Repository of Dissertations in Serbia","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u0423\u043d\u0438\u0432\u0435\u0440\u0437\u0438\u0442\u0435\u0442 \u0443 \u041a\u0440\u0430\u0433\u0443\u0458\u0435\u0432\u0446\u0443","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://nardus.mpn.gov.rs/handle/123456789/3616","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101986732","display_name":"Jelena M. Mladenovi\u0107","orcid":"https://orcid.org/0000-0002-0597-116X","observed_orcids":["https://orcid.org/0000-0002-0597-116X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jelena Mladenovi\u0107","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5101986732"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.43309998512268066,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.43309998512268066,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10915","display_name":"Trace Elements in Health","score":0.20900000631809235,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.15950000286102295,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/copper-toxicity","display_name":"copper toxicity","score":0.5389999747276306},{"id":"https://openalex.org/keywords/quercetin","display_name":"quercetin","score":0.9139999747276306},{"id":"https://openalex.org/keywords/epicatechin","display_name":"epicatechin","score":0.9779999852180481},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.9929999709129333},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8429999947547913},{"id":"https://openalex.org/keywords/antioxidant-status","display_name":"antioxidant status","score":0.8820000290870667},{"id":"https://openalex.org/keywords/liver","display_name":"liver","score":0.7129999995231628},{"id":"https://openalex.org/keywords/wilson-s-disease","display_name":"Wilson's disease","score":0.6449999809265137},{"id":"https://openalex.org/keywords/penicillamine","display_name":"D-penicillamine","score":0.7799999713897705},{"id":"https://openalex.org/keywords/thiols","display_name":"thiols","score":0.4740000069141388},{"id":"https://openalex.org/keywords/synergistic-effect","display_name":"synergistic effect","score":0.44999998807907104},{"id":"https://openalex.org/keywords/hepatoprotective-effect","display_name":"hepatoprotection","score":0.5429999828338623},{"id":"https://openalex.org/keywords/oxidative-dna-damage","display_name":"oxidative DNA damage","score":0.3919999897480011},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.8529999852180481},{"id":"https://openalex.org/keywords/lipid-hydroperoxides","display_name":"lipid hydroperoxides","score":0.39100000262260437}],"concepts":[{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.8648368716239929},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.44692230224609375},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08603730797767639}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:nardus.mpn.gov.rs:123456789/3616","doi":null,"is_oa":true,"landing_page_url":"https://nardus.mpn.gov.rs/handle/123456789/3616","pdf_url":null,"source":{"id":"https://openalex.org/S4377196110","display_name":"National Repository of Dissertations in Serbia","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u0423\u043d\u0438\u0432\u0435\u0440\u0437\u0438\u0442\u0435\u0442 \u0443 \u041a\u0440\u0430\u0433\u0443\u0458\u0435\u0432\u0446\u0443","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2883000582","doi":null,"is_oa":false,"landing_page_url":"https://nardus.mpn.gov.rs/handle/123456789/3616","pdf_url":null,"source":{"id":"https://openalex.org/S4306540431","display_name":"\u0423\u043d\u0438\u0432\u0435\u0440\u0437\u0438\u0442\u0435\u0442 \u0443 \u041a\u0440\u0430\u0433\u0443\u0458\u0435\u0432\u0446\u0443","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u0423\u043d\u0438\u0432\u0435\u0440\u0437\u0438\u0442\u0435\u0442 \u0443 \u041a\u0440\u0430\u0433\u0443\u0458\u0435\u0432\u0446\u0443","raw_type":null}],"best_oa_location":{"id":"pmh:oai:nardus.mpn.gov.rs:123456789/3616","doi":null,"is_oa":true,"landing_page_url":"https://nardus.mpn.gov.rs/handle/123456789/3616","pdf_url":null,"source":{"id":"https://openalex.org/S4377196110","display_name":"National Repository of Dissertations in Serbia","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u0423\u043d\u0438\u0432\u0435\u0440\u0437\u0438\u0442\u0435\u0442 \u0443 \u041a\u0440\u0430\u0433\u0443\u0458\u0435\u0432\u0446\u0443","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2616984745","https://openalex.org/W3092588978","https://openalex.org/W7064422109","https://openalex.org/W6999008108","https://openalex.org/W3036738469","https://openalex.org/W2905123336","https://openalex.org/W2473317302","https://openalex.org/W2285868602","https://openalex.org/W2767309162","https://openalex.org/W2506022059"],"abstract_inverted_index":{"Bakar":[0],"kao":[1,131,635,700,733],"esencijalni":[2],"mikroelement":[3],"ima":[4],"va\u017enu":[5],"ulogu":[6],"u":[7,40,44,48,70,83,103,112,134,163,184,201,210,227,266,452,463,484,493,526,552,599,603,617,664,667,674,730,735],"biolo\u0161kim":[8],"sistemima":[9],"me\u0111utim,":[10],"pove\u0107ane":[11],"koncentracije":[12,319,326,364,368,386,610],"mogu":[13,65],"da":[14,23,66,461,646,658],"izazovu":[15],"toksi\u010dne":[16,479],"efekte.":[17],"Kao":[18],"prelazni":[19],"metal,":[20],"bakar":[21,462],"mo\u017ee":[22,641],"stimuli\u0161e":[24],"produkciju":[25],"reaktivnih":[26,369],"vrsta":[27,370],"kiseonika":[28,371],"preko":[29,206],"Fenton-ove":[30],"i":[31,34,108,118,122,128,140,144,222,255,287,316,331,348,372,382,389,393,428,431,444,448,454,472,476,495,501,521,531,539,541,548,568,573,578,588,595,605,614,633,636,653,661,678,686,701,707,713,721,734,737],"Haber-Weiss-ove":[32],"reakcije":[33],"dovede":[35],"do":[36,490],"oksidativnih":[37],"o\u0161te\u0107enja":[38],"biomolekula":[39],"tkivima,":[41],"pre":[42],"svega":[43],"jetri":[45,113],"koja":[46,57],"u\u010destvuje":[47],"njegovom":[49],"metabolizmu.":[50],"\\nFlavonoidi":[51,571],"su":[52,139,297,360,451,514,659],"prirodna":[53],"biljna":[54],"polifenolna":[55],"jedinjenja":[56],"pokazuju":[58,460,575,657],"\u0161irok":[59],"spektar":[60],"biolo\u0161ke":[61],"aktivnosti.":[62],"\\nAntioksidativna":[63],"svojstva":[64],"ispolje":[67],"razli\u010ditim":[68],"mehanizmima,":[69],"direktnoj":[71],"reakciji":[72],"sa":[73,669],"reaktivnim":[74],"vrstama":[75],"ili":[76],"helacijom":[77],"jona":[78],"prelaznih":[79],"metala,":[80],"koji":[81],"bi":[82],"daljim":[84],"reakcijama":[85],"proizveli":[86],"reaktivne":[87],"vrste.":[88],"\\nCilj":[89],"istra\u017eivanja":[90,459],"ove":[91],"doktorske":[92],"disertacije":[93],"je":[94,117,158,168,418],"ispitivanje":[95,119],"efekata":[96],"subhroni\u010dne":[97,557],"intoksikacije":[98,511,558],"bakrom":[99,217,246,488,512,559],"na":[100,170,179,470,481,562,709],"hematolo\u0161ko-biohemijske":[101,482],"parametre":[102,109],"krvi,":[104],"oksidativni":[105,580],"metabolizam":[106],"eritrocita":[107,301,500,530,712],"oksidativnog":[110,136,362,564],"\\nstresa":[111],"pacova.":[114],"Tako\u0111e,":[115],"cilj":[116],"protektivnog":[120,703],"kapaciteta":[121,627],"sinergisti\u010dkog":[123],"delovanja":[124,704],"\\nflavonoida":[125],"kvercetina":[126,706],"(QE)":[127],"epikatehina":[129,708],"(EC),":[130],"\u010distih":[132],"supstanci,":[133],"uslovima":[135],"stresa.":[137],"\\nUpore\u0111ivani":[138],"efekti":[141],"primenjenih":[142],"flavonoida":[143,631,705,729],"komercijalnog":[145],"leka":[146],"D-penicilamina":[147],"(DPA),":[148],"tiolnog":[149],"\\njedinjenja":[150],"koje":[151],"se":[152,642],"koristi":[153],"za":[154,208],"tretman":[155],"oboljenja":[156],"\u010diji":[157],"uzrok":[159],"pove\u0107ano":[160],"akumuliranje":[161],"bakra":[162,447],"tkivima":[164],"(Vilsonova":[165],"\\nbolest).":[166],"\\nStudija":[167],"izvedena":[169],"mu\u017ejacima":[171],"pacova":[172,475],"soja":[173],"Wistar":[174],"albino,":[175],"8":[176],"nedelja":[177],"starosti":[178],"po\u010detku":[180],"eksperimenta,":[181],"\\nnasumi\u010dno":[182],"podeljenih":[183],"5":[185,213,242],"grupa":[186],"po":[187],"7":[188,281],"\u017eivotinja:":[189],"(1)":[190],"kontrolna":[191],"(0.3":[192],"ml":[193,229,268],"fiziolo\u0161kog":[194],"rastvora,":[195],"i.p.);":[196],"(2)":[197],"tretirana":[198,216,245,284],"\\nbakrom":[199],"(CuCl2\u00b72H2O":[200],"koncentraciji":[202],"od":[203,212],"560":[204],"mg/L)":[205],"vode":[207],"pi\u0107e":[209],"trajanju":[211],"nedelja;":[214],"(3)":[215],"\\n(na":[218],"na\u010din":[219,248,290],"opisan":[220,249],"prethodno)":[221],"DPA":[223],"(50":[224],"mg/kg":[225],"TT,":[226,265],"0.3":[228,267],"redestilovane":[230,269],"vode,":[231,270],"i.p.)":[232,271],"svakog":[233,272],"drugog":[234],"dana":[235,274],"tokom":[236],"\\nposlednje":[237],"2":[238],"nedelje":[239,278],"eksperimenta":[240,279],"(ukupno":[241,280],"injekcija);":[243,282],"(4)":[244],"(na":[247,289],"prethodno),":[250],"a":[251],"zatim":[252],"\\nflavonoidima":[253],"QE":[254,286,572,587,632,660],"EC":[256,288,574,589,662],"(40":[257],"mg":[258,263],"QE/kg":[259],"TT":[260],"+":[261],"40":[262],"EC/kg":[264],"tre\u0107eg":[273],"\\ntokom":[275],"poslednje":[276],"3":[277],"(5)":[283],"flavonoidima":[285],"\\nopisan":[291],"prethodno).":[292],"U":[293,352,407],"punoj":[294],"krvi":[295],"odre\u0111ivani":[296,359],"hematolo\u0161ki":[298,314],"parametri:":[299,318],"broj":[300,308,311],"(RBC),":[302],"koncentracija":[303],"\\nhemoglobina":[304],"(Hb),":[305],"hematokrit":[306],"(Hct),":[307],"leukocita":[309],"(WBC),":[310],"trombocita":[312],"(Plt),":[313],"indeksi,":[315],"\\nbiohemijski":[317],"elektrolita":[320],"(K,":[321],"Na,":[322],"Ca,":[323],"Fe,":[324],"fosfata),":[325],"ukupnih":[327],"proteina,":[328],"\\nalbumina,":[329],"glukoze":[330],"ukupnog":[332,504],"holesterola,":[333,505],"aktivnosti":[334,394,432,515],"enzima":[335,395,433,516,554,621],"aspartat":[336],"aminotransferaze":[337],"(AST),":[338],"alanin":[339],"\\naminotransferaze":[340],"(ALT),":[341],"alkalne":[342],"fosfataze":[343],"(ALP),":[344],"gama-glutamil":[345],"transpeptidaze":[346],"(GGT)":[347],"laktat":[349],"dehidrogenaze":[350],"\\n(LDH).":[351],"lizatu":[353],"eritrocita,":[354],"primenom":[355,413],"standardnih":[356,414],"analiti\u010dkih":[357,415],"metoda,":[358],"markeri":[361],"\\nstresa:":[363],"lipidnih":[365],"peroksida":[366,380],"(LPO),":[367],"azota":[373],"(superoksid":[374],"\\nanjon":[375],"radikala":[376],"(O2":[377],"\\n\u2022-),":[378],"vodonik":[379],"(H2O2)":[381],"nitrita":[383],"(NO2":[384],"\\n-)),":[385],"redukovanog":[387],"(GSH)":[388],"\\noksidovanog":[390],"glutationa":[391],"(GSSG)":[392],"superoksid-dismuze":[396],"(SOD),":[397],"katalaze":[398],"(CAT),":[399],"glutation-":[400],"\\nperoksidaze":[401],"(GSH-Px),":[402],"glutation-reduktaze":[403],"(GR),":[404],"glutation-S-transferaze":[405],"(GST).":[406],"izolovanom":[408],"tkivu":[409,496,569,606,687],"jetre,":[410,497],"\\nnakon":[411],"homogenizacije,":[412],"metoda":[416],"tako\u0111e":[417,560,656],"odre\u0111en":[419],"redoks":[420],"status":[421],"\\n(koncentracije":[422],"LPO,":[423],"neenzimskih":[424,543],"antioksidanata":[425,612],"GSH,":[426],"GSSG":[427],"Vit":[429,549,615],"C,":[430],"AOS:":[434],"ukupne":[435],"SOD,":[436,438,440],"\\nCuZn":[437],"Mn":[439],"CAT,":[441],"GSH-Px,":[442],"GR":[443],"GST).":[445],"Koncentracije":[446],"ceruloplazmina":[449],"odre\u0111ene":[450],"plazmi":[453],"\\nsupernatantu":[455],"tkiva":[456,532,715],"jetre.":[457,570,607,688,716],"\\nRezultati":[458,655],"subhroni\u010dnom":[464],"tretmanu":[465],"ispoljava":[466,677],"direktan":[467],"prooksidativni":[468],"\\nefekat":[469],"eritrocite":[471],"tkivo":[473],"jetre":[474,525,533],"pokazuje":[477],"zna\u010dajne":[478],"efekte":[480,680],"\\nprocese":[483],"krvi.":[485],"Subhroni\u010dna":[486],"intoksikacija":[487],"dovodi":[489],"pove\u0107anja":[491],"LPO":[492],"eritrocitima":[494,567,604,685],"\\nuzrokuje":[498],"hemolizu":[499],"anemiju,":[502],"porast":[503],"poreme\u0107aj":[506],"homeostaze":[507],"elektrolita.":[508],"Nakon":[509],"\\nsubhroni\u010dne":[510],"povi\u0161ene":[513],"AST,":[517],"ALT,":[518],"ALP,":[519],"GGT":[520],"LDH,":[522],"markera":[523],"\\ncitotoksi\u010dnosti":[524],"serumu.":[527],"Oksidativnim":[528],"o\u0161te\u0107enjima":[529],"doprinosi":[534],"pove\u0107ana":[535],"\\nprodukcija":[536],"O2":[537,651],"\\n\u2022-":[538,652],"H2O2":[540],"smanjenje":[542],"antioksidanata,":[544],"\u0107elijskog":[545],"pula":[546],"GSH":[547,613],"C.":[550],"Promene":[551],"\\naktivnostima":[553],"AOS":[555],"posle":[556],"ukazuju":[561],"pojavu":[563],"stresa":[565],"\\nu":[566,684],"antioksidativnu":[576],"sposobnost":[577],"umanjuju":[579],"stres":[581],"nastao":[582],"nakon":[583],"\\nsubhroni\u010dnog":[584],"izlaganja":[585],"bakru.":[586],"stabilizuju":[590],"membrane,":[591],"blokiraju":[592],"lipidnu":[593],"peroksidaciju":[594],"time":[596],"igraju":[597],"\\nulogu":[598],"ubla\u017eavanju":[600],"manifestacija":[601],"toksi\u010dnosti":[602],"Zna\u010dajno":[608],"pove\u0107avaju":[609],"\\nneenzimskih":[611],"C":[616],"\u0107elijama,":[618],"indukuju":[619],"sintezu":[620],"AOS,":[622],"\u010dime":[623],"doprinose":[624],"pove\u0107anju":[625],"\\nantioksidativnog":[626],"\u0107elija.":[628],"Sinergisti\u010dko":[629],"delovanje":[630],"EC,":[634],"citoprotektivna":[637],"uloga":[638],"\\nkoju":[639],"pokazuju,":[640],"pripisati":[643],"njihovoj":[644],"sposobnosti":[645],"heliraju":[647],"metale":[648],"i/ili":[649],"uklanjaju":[650],"N2O2.":[654],"efektivniji":[663],"antioksidativnom":[665],"delovanju":[666],"pore\u0111enju":[668],"DPA,":[670],"\\nkoji":[671],"pored":[672],"efikasnosti":[673],"heliranju":[675],"metala":[676],"prooksidativne":[679],"pove\u0107anjem":[681],"lipidne":[682],"peroksidacije":[683],"\\nOvo":[689],"istra\u017eivanje":[690],"predstavlja":[691],"doprinos":[692],"kompletiranju":[693],"nau\u010dnih":[694],"saznanja":[695],"o":[696],"toksi\u010dnim":[697],"efektima":[698],"bakra,":[699],"\\nkompleksnosti":[702],"oksidativno-antioksidativni":[710],"\\nstatus":[711],"\u0107elija":[714],"Zbog":[717],"\u0161irokog":[718],"spektra":[719],"biohemijskih":[720],"farmakolo\u0161kih":[722],"dejstava,":[723],"posebno":[724],"\\ntreba":[725],"istaknuti":[726],"zna\u010daj":[727],"ispitivanih":[728],"zdravoj":[731],"ishrani,":[732],"prevenciji":[736],"terapiji":[738],"mnogih":[739],"\\noboljenja.":[740]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-08-03T00:00:00"}