{"id":"https://openalex.org/W287882831","doi":"https://doi.org/10.1023/a:1006889108673","title":"Effect of iron on fluconazole activity against Candida albicans in presence of human serum or monocyte-derived macrophages","display_name":"Effect of iron on fluconazole activity against Candida albicans in presence of human serum or monocyte-derived macrophages","publication_year":1997,"publication_date":"1997-04-01","ids":{"openalex":"https://openalex.org/W287882831","doi":"https://doi.org/10.1023/a:1006889108673","mag":"287882831","pmid":"https://pubmed.ncbi.nlm.nih.gov/9404022"},"language":"en","primary_location":{"id":"doi:10.1023/a:1006889108673","doi":"https://doi.org/10.1023/a:1006889108673","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1006889108673","pdf_url":null,"source":{"id":"https://openalex.org/S154926289","display_name":"Mycopathologia","issn_l":"0301-486X","issn":["0301-486X","0369-299X","1573-0832","2214-6989"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mycopathologia","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001000514","display_name":"A. Yuriko Minn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801022843","display_name":"Santa Clara Valley Medical Center","ror":"https://ror.org/02v7qv571","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801022843","https://openalex.org/I4210115301"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuriko Minn","raw_affiliation_strings":["Department of Medicine, Santa Clara Valley Medical Center, San Jose, CA, USA","Division of Infectious Diseases, Department of Medicine, Santa Clara Valley Medical Center, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Santa Clara Valley Medical Center, San Jose, CA, USA","institution_ids":["https://openalex.org/I2801022843"]},{"raw_affiliation_string":"Division of Infectious Diseases, Department of Medicine, Santa Clara Valley Medical Center, USA","institution_ids":["https://openalex.org/I2801022843"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009082087","display_name":"Elmer Brummer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801022843","display_name":"Santa Clara Valley Medical Center","ror":"https://ror.org/02v7qv571","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801022843","https://openalex.org/I4210115301"]},{"id":"https://openalex.org/I4210125992","display_name":"California Institute for Medical Research","ror":"https://ror.org/03cf9xg09","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210125992"]},{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elmer Brummer","raw_affiliation_strings":["California Institute for Medical Research, San Jose, USA","Division of Infectious Diseases and Geographic Medicine, Stanford University Medical School, Stanford, CA, USA","Division of Infectious Diseases, Department of Medicine, Santa Clara Valley Medical Center, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"California Institute for Medical Research, San Jose, USA","institution_ids":["https://openalex.org/I4210125992"]},{"raw_affiliation_string":"Division of Infectious Diseases and Geographic Medicine, Stanford University Medical School, Stanford, CA, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Division of Infectious Diseases, Department of Medicine, Santa Clara Valley Medical Center, USA","institution_ids":["https://openalex.org/I2801022843"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021143803","display_name":"David A. Stevens","orcid":"https://orcid.org/0000-0002-5861-5716","observed_orcids":["https://orcid.org/0000-0002-5861-5716"]},"institutions":[{"id":"https://openalex.org/I2801022843","display_name":"Santa Clara Valley Medical Center","ror":"https://ror.org/02v7qv571","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801022843","https://openalex.org/I4210115301"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David A. Stevens","raw_affiliation_strings":["Division of Infectious Diseases, Department of Medicine, Santa Clara Valley Medical Center, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases, Department of Medicine, Santa Clara Valley Medical Center, USA","institution_ids":["https://openalex.org/I2801022843"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":null,"fwci":1.393,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.80945052,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"138","issue":"1","first_page":"29","last_page":"35"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fluconazole","display_name":"fluconazole","score":0.9789999723434448},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":1.0},{"id":"https://openalex.org/keywords/iron-overload","display_name":"iron overload","score":0.8880000114440918},{"id":"https://openalex.org/keywords/iron-starvation","display_name":"iron starvation","score":0.6330000162124634},{"id":"https://openalex.org/keywords/human-serum","display_name":"human serum","score":0.8510000109672546},{"id":"https://openalex.org/keywords/monocyte-derived-macrophages","display_name":"monocyte-derived macrophages","score":0.9800000190734863},{"id":"https://openalex.org/keywords/candidiasis","display_name":"candidiasis","score":0.7099999785423279},{"id":"https://openalex.org/keywords/antifungal-synergy","display_name":"antifungal synergy","score":0.7730000019073486},{"id":"https://openalex.org/keywords/transferrin","display_name":"transferrin","score":0.7450000047683716},{"id":"https://openalex.org/keywords/apotransferrin","display_name":"apotransferrin","score":0.8820000290870667},{"id":"https://openalex.org/keywords/candidacidal-activity","display_name":"candidacidal activity","score":0.8220000267028809},{"id":"https://openalex.org/keywords/fungistatic-activity","display_name":"fungistatic activity","score":0.8019999861717224}],"concepts":[{"id":"https://openalex.org/C2780651595","wikidata":"https://www.wikidata.org/wiki/Q411478","display_name":"Fluconazole","level":3,"score":0.9424977898597717},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.849304735660553},{"id":"https://openalex.org/C22814914","wikidata":"https://www.wikidata.org/wiki/Q410473","display_name":"Transferrin","level":2,"score":0.7771850824356079},{"id":"https://openalex.org/C2781184567","wikidata":"https://www.wikidata.org/wiki/Q107244","display_name":"Monocyte","level":2,"score":0.6660075783729553},{"id":"https://openalex.org/C145081991","wikidata":"https://www.wikidata.org/wiki/Q2576388","display_name":"Corpus albicans","level":3,"score":0.6227024793624878},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5514949560165405},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5424808263778687},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5035561919212341},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.43518149852752686},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.42009395360946655},{"id":"https://openalex.org/C32264632","wikidata":"https://www.wikidata.org/wiki/Q1134983","display_name":"Transferrin receptor","level":3,"score":0.4163437485694885},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40174877643585205},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3634037375450134},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3592842221260071},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20182183384895325},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.15458974242210388},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001059","descriptor_name":"Apoproteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001769","descriptor_name":"Blood","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007501","descriptor_name":"Iron","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007501","descriptor_name":"Iron","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014168","descriptor_name":"Transferrin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015725","descriptor_name":"Fluconazole","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1023/a:1006889108673","doi":"https://doi.org/10.1023/a:1006889108673","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1006889108673","pdf_url":null,"source":{"id":"https://openalex.org/S154926289","display_name":"Mycopathologia","issn_l":"0301-486X","issn":["0301-486X","0369-299X","1573-0832","2214-6989"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mycopathologia","raw_type":"journal-article"},{"id":"pmid:9404022","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9404022","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mycopathologia","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1489466659","https://openalex.org/W1491972272","https://openalex.org/W1940720973","https://openalex.org/W1997948374","https://openalex.org/W1998227718","https://openalex.org/W2000628507","https://openalex.org/W2017189230","https://openalex.org/W2049726478","https://openalex.org/W2056683211","https://openalex.org/W2058354220","https://openalex.org/W2064083708","https://openalex.org/W2067266074","https://openalex.org/W2095979534","https://openalex.org/W2105653347","https://openalex.org/W2113719141","https://openalex.org/W2140389942"],"related_works":["https://openalex.org/W4407239752","https://openalex.org/W7000428640","https://openalex.org/W7099425361","https://openalex.org/W4293117574","https://openalex.org/W2005311773","https://openalex.org/W1998227718","https://openalex.org/W7015832677","https://openalex.org/W2158345992","https://openalex.org/W2017049578","https://openalex.org/W2005363381"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}