{"id":"https://openalex.org/W28713804","doi":"https://doi.org/10.1089/jmf.2013.0151","title":"Pharmacological Evidence of \u03b1 2 -Adrenergic Receptors in the Hypotensive Effect of Platonia insignis Mart.","display_name":"Pharmacological Evidence of \u03b1 2 -Adrenergic Receptors in the Hypotensive Effect of Platonia insignis Mart.","publication_year":2014,"publication_date":"2014-07-23","ids":{"openalex":"https://openalex.org/W28713804","doi":"https://doi.org/10.1089/jmf.2013.0151","mag":"28713804","pmid":"https://pubmed.ncbi.nlm.nih.gov/25055183","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4186803"},"language":"en","primary_location":{"id":"doi:10.1089/jmf.2013.0151","doi":"https://doi.org/10.1089/jmf.2013.0151","is_oa":false,"landing_page_url":"https://doi.org/10.1089/jmf.2013.0151","pdf_url":null,"source":{"id":"https://openalex.org/S78718175","display_name":"Journal of Medicinal Food","issn_l":"1096-620X","issn":["1096-620X","1557-7600"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","kci-registered","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medicinal Food","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4186803/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057625752","display_name":"Marcelo Bezerra Mendes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marcelo Bezerra Mendes","raw_affiliation_strings":["Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002591772","display_name":"Jos\u00e9 Couras da Silva\u2010Filho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Couras da Silva-Filho","raw_affiliation_strings":["Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066061487","display_name":"Carla Kelly Barroso Sabino","orcid":"https://orcid.org/0000-0003-1532-0990","observed_orcids":["https://orcid.org/0000-0003-1532-0990"]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Carla Kelly Barroso Sabino","raw_affiliation_strings":["Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020071575","display_name":"Daniel Dias Rufino Arcanjo","orcid":"https://orcid.org/0000-0001-7021-2744","observed_orcids":["https://orcid.org/0000-0001-7021-2744"]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Daniel Dias Rufino Arcanjo","raw_affiliation_strings":["Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109271270","display_name":"Cleyton Marcos Melo Sousa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Cleyton Marcos Melo Sousa","raw_affiliation_strings":["Department of Chemistry, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012757336","display_name":"Isabella Cristhina Gon\u00e7alves Costa","orcid":"https://orcid.org/0000-0002-2948-4892","observed_orcids":["https://orcid.org/0000-0002-2948-4892"]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Isabella Cristhina Gon\u00e7alves Costa","raw_affiliation_strings":["Department of Chemistry, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001253459","display_name":"Mariana Helena Chaves","orcid":"https://orcid.org/0000-0003-1541-6757","observed_orcids":["https://orcid.org/0000-0003-1541-6757"]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Mariana Helena Chaves","raw_affiliation_strings":["Department of Chemistry, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101774863","display_name":"Rita de C\u00e1ssia Meneses Oliveira","orcid":"https://orcid.org/0000-0003-1669-4628","observed_orcids":["https://orcid.org/0000-0003-1669-4628"]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Rita de C\u00e1ssia Meneses Oliveira","raw_affiliation_strings":["Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062790000","display_name":"Alde\u00eddia Pereira de Oliveira","orcid":"https://orcid.org/0000-0003-3286-4295","observed_orcids":["https://orcid.org/0000-0003-3286-4295"]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Alde\u00eddia P. Oliveira","raw_affiliation_strings":["Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Federal University of Piau\u00ed, Teresina, Brazil","institution_ids":["https://openalex.org/I3121799822"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5062790000"],"corresponding_institution_ids":["https://openalex.org/I3121799822"],"apc_list":null,"apc_paid":null,"fwci":0.3583,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.62041482,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"17","issue":"10","first_page":"1079","last_page":"1085"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12497","display_name":"Traditional and Medicinal Uses of Annonaceae","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/platonia-insignis","display_name":"Platonia insignis","score":1.0},{"id":"https://openalex.org/keywords/clusiaceae","display_name":"Clusiaceae","score":0.824999988079071},{"id":"https://openalex.org/keywords/alpha2-adrenergic-receptors","display_name":"alpha2-adrenoceptors","score":0.8700000047683716},{"id":"https://openalex.org/keywords/antihypertensive-effect","display_name":"antihypertensive effect","score":0.9520000219345093},{"id":"https://openalex.org/keywords/bradycardia","display_name":"bradycardia","score":0.8489999771118164},{"id":"https://openalex.org/keywords/tachycardia","display_name":"tachycardia","score":0.9399999976158142},{"id":"https://openalex.org/keywords/yohimbine","display_name":"yohimbine","score":0.8429999947547913},{"id":"https://openalex.org/keywords/cardiovascular-effects","display_name":"cardiovascular effects","score":0.546999990940094},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.6389999985694885},{"id":"https://openalex.org/keywords/l-name","display_name":"L-NAME","score":0.5839999914169312},{"id":"https://openalex.org/keywords/verapamil","display_name":"verapamil","score":0.8220000267028809},{"id":"https://openalex.org/keywords/propranolol","display_name":"propranolol","score":0.9890000224113464},{"id":"https://openalex.org/keywords/hexamethonium","display_name":"hexamethonium","score":0.9990000128746033}],"concepts":[{"id":"https://openalex.org/C40465926","wikidata":"https://www.wikidata.org/wiki/Q410568","display_name":"Adrenergic receptor","level":3,"score":0.6591774225234985},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.6346480846405029},{"id":"https://openalex.org/C158453852","wikidata":"https://www.wikidata.org/wiki/Q4684738","display_name":"Adrenergic","level":3,"score":0.6130392551422119},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.529809832572937},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.42641162872314453},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35196053981781006},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34715014696121216},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32944902777671814},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.32834747433662415}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018341","descriptor_name":"Receptors, Adrenergic, alpha-2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018341","descriptor_name":"Receptors, Adrenergic, alpha-2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D028084","descriptor_name":"Clusiaceae","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058647","descriptor_name":"Adrenergic alpha-2 Receptor Agonists","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1089/jmf.2013.0151","doi":"https://doi.org/10.1089/jmf.2013.0151","is_oa":false,"landing_page_url":"https://doi.org/10.1089/jmf.2013.0151","pdf_url":null,"source":{"id":"https://openalex.org/S78718175","display_name":"Journal of Medicinal Food","issn_l":"1096-620X","issn":["1096-620X","1557-7600"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","kci-registered","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medicinal Food","raw_type":"journal-article"},{"id":"pmid:25055183","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25055183","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of medicinal food","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4186803","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4186803/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Med Food","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4186803","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4186803/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Med Food","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"},{"id":"https://openalex.org/F4320322989","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Piau\u00ed","ror":"https://ror.org/026zht694"},{"id":"https://openalex.org/F4320323198","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1745781907","https://openalex.org/W1948973457","https://openalex.org/W1971774778","https://openalex.org/W1973660985","https://openalex.org/W1985802417","https://openalex.org/W1987405059","https://openalex.org/W1995364836","https://openalex.org/W2005634620","https://openalex.org/W2013826583","https://openalex.org/W2023717009","https://openalex.org/W2048354268","https://openalex.org/W2055910164","https://openalex.org/W2070169736","https://openalex.org/W2076961531","https://openalex.org/W2079077913","https://openalex.org/W2079204782","https://openalex.org/W2080549024","https://openalex.org/W2091525143","https://openalex.org/W2091652119","https://openalex.org/W2097913275","https://openalex.org/W2141659719","https://openalex.org/W2164892676","https://openalex.org/W2171757733","https://openalex.org/W4285719527","https://openalex.org/W4406054923"],"related_works":["https://openalex.org/W7203549642","https://openalex.org/W2187647836","https://openalex.org/W1963813223","https://openalex.org/W2403167877","https://openalex.org/W1836168874","https://openalex.org/W1979139749","https://openalex.org/W2045527398","https://openalex.org/W2062013292","https://openalex.org/W2086482368","https://openalex.org/W2320581569"],"abstract_inverted_index":{"Platonia":[0],"insignis":[1,33],"Mart.":[2],"(Clusiaceae)":[3],"is":[4],"a":[5,119],"medicinal":[6],"plant":[7],"from":[8,129],"the":[9,17,21,31,37,59,64,92,107,137,149,164,171],"Brazilian":[10],"Amazon":[11],"region.":[12],"The":[13,69,126],"present":[14],"study":[15],"evaluated":[16],"biological":[18],"potential":[19],"of":[20,30,40,121],"ethanol":[22],"extract":[23],"(Pi-EtOH)":[24],"and":[25,47,58,63,75,86,89,110,116,143],"ethyl":[26],"acetate":[27],"fraction":[28],"(Pi-EtOAc)":[29],"P.":[32],"fruit":[34],"shells":[35],"on":[36],"cardiovascular":[38],"system":[39],"rats.":[41],"Pi-EtOH":[42,70],"or":[43],"Pi-EtOAc":[44,130,165],"(12.5,":[45],"25,":[46],"50":[48,122],"mg/kg)":[49],"was":[50,131,152],"administered":[51],"intravenously":[52],"in":[53,81,136,174],"normotensive":[54],"rats":[55],"(260-300":[56],"g),":[57],"mean":[60],"arterial":[61],"pressure":[62],"heart":[65],"rate":[66],"were":[67],"monitored.":[68],"induced":[71,95],"hypotension":[72,96],"(-11.56\u00b10.89,":[73],"-7.43\u00b10.85,":[74],"-17.56\u00b11.97":[76],"mmHg)":[77,100],"followed":[78,103],"by":[79,104],"bradycardia":[80,117],"two":[82],"highest":[83],"doses":[84],"(-8.89\u00b13.62":[85],"-15.79\u00b11.83":[87],"beats/min)":[88,115],"Pi-EtOAc,":[90],"at":[91,106,118],"same":[93],"doses,":[94],"(-11.2\u00b11.03,":[97],"-14.48\u00b11.13,":[98],"-29.89\u00b12.67":[99],"more":[101],"intensively,":[102],"tachycardia":[105],"dose":[108,120],"12.5":[109],"25":[111],"mg/kg":[112,123],"(15.64\u00b12.06,":[113],"19.31\u00b11.92":[114],"(-9.98\u00b17.33":[124],"beats/min).":[125],"hypotensive":[127,150,176],"response":[128],"not":[132],"attenuated":[133],"when":[134,146],"used":[135],"pretreatment":[138],"with":[139],"L-NAME,":[140],"verapamil,":[141],"propranolol,":[142],"hexamethonium.":[144],"However,":[145],"using":[147],"yohimbine,":[148],"effect":[151],"inhibited":[153],"(-4.42\u00b11.28":[154],"(P<.05),":[155,157],"-3.29\u00b10.99":[156],"2.06\u00b11.18":[158],"mmHg":[159],"(P<.05);":[160],"Student's":[161],"t-test).":[162],"Hence,":[163],"seems":[166],"to":[167,170],"act":[168],"similarly":[169],"\u03b12-adrenergic":[172],"agonist":[173],"this":[175],"effect.":[177]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}