{"id":"https://openalex.org/W2860176197","doi":"https://doi.org/10.3892/etm.2018.6429","title":"H1N1 influenza virus epitopes classified by monoclonal antibodies","display_name":"H1N1 influenza virus epitopes classified by monoclonal antibodies","publication_year":2018,"publication_date":"2018-07-09","ids":{"openalex":"https://openalex.org/W2860176197","doi":"https://doi.org/10.3892/etm.2018.6429","mag":"2860176197","pmid":"https://pubmed.ncbi.nlm.nih.gov/30186431","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6122413"},"language":"en","primary_location":{"id":"doi:10.3892/etm.2018.6429","doi":"https://doi.org/10.3892/etm.2018.6429","is_oa":true,"landing_page_url":"https://doi.org/10.3892/etm.2018.6429","pdf_url":"http://www.spandidos-publications.com/10.3892/etm.2018.6429/download","source":{"id":"https://openalex.org/S151424340","display_name":"Experimental and Therapeutic Medicine","issn_l":"1792-0981","issn":["1792-0981","1792-1015"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and Therapeutic Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://www.spandidos-publications.com/10.3892/etm.2018.6429/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101728544","display_name":"Chunyan Guo","orcid":"https://orcid.org/0000-0001-7188-2256","observed_orcids":["https://orcid.org/0000-0001-7188-2256"]},"institutions":[{"id":"https://openalex.org/I4210090354","display_name":"Shaanxi Provincial People's Hospital","ror":"https://ror.org/009czp143","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunyan Guo","raw_affiliation_strings":["Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China","institution_ids":["https://openalex.org/I4210090354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076797290","display_name":"Haixiang Zhang","orcid":"https://orcid.org/0000-0003-1496-7098","observed_orcids":["https://orcid.org/0000-0003-1496-7098"]},"institutions":[{"id":"https://openalex.org/I4210090354","display_name":"Shaanxi Provincial People's Hospital","ror":"https://ror.org/009czp143","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haixiang Zhang","raw_affiliation_strings":["Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China","institution_ids":["https://openalex.org/I4210090354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101584148","display_name":"Xin Xie","orcid":"https://orcid.org/0000-0002-7132-5609","observed_orcids":["https://orcid.org/0000-0002-7132-5609"]},"institutions":[{"id":"https://openalex.org/I37802460","display_name":"Northwest University","ror":"https://ror.org/00z3td547","country_code":"CN","type":"education","lineage":["https://openalex.org/I37802460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xin Xie","raw_affiliation_strings":["Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an, Shaanxi 710069, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an, Shaanxi 710069, P.R. China","institution_ids":["https://openalex.org/I37802460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100611154","display_name":"Yang Liu","orcid":"https://orcid.org/0000-0002-5815-6740","observed_orcids":["https://orcid.org/0000-0002-5815-6740"]},"institutions":[{"id":"https://openalex.org/I4210090354","display_name":"Shaanxi Provincial People's Hospital","ror":"https://ror.org/009czp143","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Liu","raw_affiliation_strings":["Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China","institution_ids":["https://openalex.org/I4210090354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103865764","display_name":"Lijun Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210090354","display_name":"Shaanxi Provincial People's Hospital","ror":"https://ror.org/009czp143","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lijun Sun","raw_affiliation_strings":["Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China","institution_ids":["https://openalex.org/I4210090354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034470472","display_name":"Huijin Li","orcid":"https://orcid.org/0000-0002-5261-2450","observed_orcids":["https://orcid.org/0000-0002-5261-2450"]},"institutions":[{"id":"https://openalex.org/I4210107780","display_name":"Xi'an Medical University","ror":"https://ror.org/01fmc2233","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210107780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huijin Li","raw_affiliation_strings":["Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi'an Medical University, Xi'an, Shaanxi 710021, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi'an Medical University, Xi'an, Shaanxi 710021, P.R. China","institution_ids":["https://openalex.org/I4210107780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040709348","display_name":"Pengbo Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088591","display_name":"Xian Center for Disease Control and Prevention","ror":"https://ror.org/00983c961","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210088591"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pengbo Yu","raw_affiliation_strings":["Center of Shaanxi Provincial Disease Control and Prevention, Institute of Viral Diseases, Xi'an, Shaanxi 710052, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Shaanxi Provincial Disease Control and Prevention, Institute of Viral Diseases, Xi'an, Shaanxi 710052, P.R. China","institution_ids":["https://openalex.org/I4210088591"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hanyu Hu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210090354","display_name":"Shaanxi Provincial People's Hospital","ror":"https://ror.org/009czp143","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hanyu Hu","raw_affiliation_strings":["Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China","institution_ids":["https://openalex.org/I4210090354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073650932","display_name":"Jingying Sun","orcid":"https://orcid.org/0000-0002-4167-9414","observed_orcids":["https://orcid.org/0000-0002-4167-9414"]},"institutions":[{"id":"https://openalex.org/I4210090354","display_name":"Shaanxi Provincial People's Hospital","ror":"https://ror.org/009czp143","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingying Sun","raw_affiliation_strings":["Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China","institution_ids":["https://openalex.org/I4210090354"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yuan Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210090354","display_name":"Shaanxi Provincial People's Hospital","ror":"https://ror.org/009czp143","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuan Li","raw_affiliation_strings":["Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China","institution_ids":["https://openalex.org/I4210090354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100946660","display_name":"Qing Feng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210090354","display_name":"Shaanxi Provincial People's Hospital","ror":"https://ror.org/009czp143","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qing Feng","raw_affiliation_strings":["Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China","institution_ids":["https://openalex.org/I4210090354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103400111","display_name":"Xiangrong Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210090354","display_name":"Shaanxi Provincial People's Hospital","ror":"https://ror.org/009czp143","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiangrong Zhao","raw_affiliation_strings":["Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China","institution_ids":["https://openalex.org/I4210090354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110567393","display_name":"Daoyan Liang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210090354","display_name":"Shaanxi Provincial People's Hospital","ror":"https://ror.org/009czp143","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Daoyan Liang","raw_affiliation_strings":["Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China","institution_ids":["https://openalex.org/I4210090354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100422422","display_name":"Zhen Wang","orcid":"https://orcid.org/0000-0003-3173-6961","observed_orcids":["https://orcid.org/0000-0003-3173-6961"]},"institutions":[{"id":"https://openalex.org/I4210090354","display_name":"Shaanxi Provincial People's Hospital","ror":"https://ror.org/009czp143","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhen Wang","raw_affiliation_strings":["Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China","institution_ids":["https://openalex.org/I4210090354"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101598033","display_name":"Jun Hu","orcid":"https://orcid.org/0000-0001-5990-6796","observed_orcids":["https://orcid.org/0000-0001-5990-6796"]},"institutions":[{"id":"https://openalex.org/I4210090354","display_name":"Shaanxi Provincial People's Hospital","ror":"https://ror.org/009czp143","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210090354"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jun Hu","raw_affiliation_strings":["Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China","institution_ids":["https://openalex.org/I4210090354"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5101598033"],"corresponding_institution_ids":["https://openalex.org/I4210090354"],"apc_list":null,"apc_paid":null,"fwci":1.1253,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.751094,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"16","issue":"3","first_page":"2001","last_page":"2007"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10167","display_name":"Influenza Virus Research Studies","score":0.8773999810218811,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10167","display_name":"Influenza Virus Research Studies","score":0.8773999810218811,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.12210000306367874,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/h1n1-influenza-virus","display_name":"H1N1 influenza virus","score":0.9509999752044678},{"id":"https://openalex.org/keywords/hemagglutinin","display_name":"hemagglutinin","score":0.9459999799728394},{"id":"https://openalex.org/keywords/linear-epitopes","display_name":"linear epitopes","score":0.906000018119812},{"id":"https://openalex.org/keywords/monoclonal-antibodies","display_name":"monoclonal antibodies","score":0.9810000061988831},{"id":"https://openalex.org/keywords/epitope-prediction","display_name":"epitope prediction","score":0.8500000238418579},{"id":"https://openalex.org/keywords/multi-epitope-vaccine-design","display_name":"multi-epitope vaccine design","score":0.8309999704360962},{"id":"https://openalex.org/keywords/universal-influenza-vaccine","display_name":"universal influenza vaccine","score":0.8690000176429749},{"id":"https://openalex.org/keywords/2009-h1n1-pandemic","display_name":"2009 H1N1 pandemic","score":0.8050000071525574},{"id":"https://openalex.org/keywords/seasonal-influenza","display_name":"seasonal influenza","score":0.8479999899864197},{"id":"https://openalex.org/keywords/influenza-a-virus","display_name":"influenza A virus","score":0.5699999928474426},{"id":"https://openalex.org/keywords/antigen-antibody-specificity","display_name":"antigen-antibody specificity","score":0.718999981880188},{"id":"https://openalex.org/keywords/epitope-mapping","display_name":"epitope mapping","score":0.5649999976158142}],"concepts":[{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.9589378833770752},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.795494019985199},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.7437076568603516},{"id":"https://openalex.org/C2778692840","wikidata":"https://www.wikidata.org/wiki/Q9136673","display_name":"Hemagglutinin (influenza)","level":3,"score":0.673735499382019},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6628527045249939},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.652458131313324},{"id":"https://openalex.org/C7842527","wikidata":"https://www.wikidata.org/wiki/Q575258","display_name":"Antigenic drift","level":4,"score":0.6197502017021179},{"id":"https://openalex.org/C2777546802","wikidata":"https://www.wikidata.org/wiki/Q834390","display_name":"Influenza A virus","level":3,"score":0.5823525786399841},{"id":"https://openalex.org/C180915046","wikidata":"https://www.wikidata.org/wiki/Q575264","display_name":"Original antigenic sin","level":5,"score":0.5341711640357971},{"id":"https://openalex.org/C82988372","wikidata":"https://www.wikidata.org/wiki/Q5628866","display_name":"H5N1 genetic structure","level":5,"score":0.5097233653068542},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.47281375527381897},{"id":"https://openalex.org/C191942190","wikidata":"https://www.wikidata.org/wiki/Q4774739","display_name":"Antigenic variation","level":3,"score":0.47222900390625},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4322185516357422},{"id":"https://openalex.org/C86282344","wikidata":"https://www.wikidata.org/wiki/Q575314","display_name":"Antigenic shift","level":5,"score":0.423905611038208},{"id":"https://openalex.org/C79029880","wikidata":"https://www.wikidata.org/wiki/Q901755","display_name":"GenBank","level":3,"score":0.4232221841812134},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.19828814268112183},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.17560738325119019},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14549365639686584},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13548201322555542},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0844389796257019},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.08286288380622864},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3892/etm.2018.6429","doi":"https://doi.org/10.3892/etm.2018.6429","is_oa":true,"landing_page_url":"https://doi.org/10.3892/etm.2018.6429","pdf_url":"http://www.spandidos-publications.com/10.3892/etm.2018.6429/download","source":{"id":"https://openalex.org/S151424340","display_name":"Experimental and Therapeutic Medicine","issn_l":"1792-0981","issn":["1792-0981","1792-1015"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and Therapeutic Medicine","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5076623","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6122413","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:30186431","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30186431","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and therapeutic medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6122413","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6122413/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Exp Ther Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3892/etm.2018.6429","doi":"https://doi.org/10.3892/etm.2018.6429","is_oa":true,"landing_page_url":"https://doi.org/10.3892/etm.2018.6429","pdf_url":"http://www.spandidos-publications.com/10.3892/etm.2018.6429/download","source":{"id":"https://openalex.org/S151424340","display_name":"Experimental and Therapeutic Medicine","issn_l":"1792-0981","issn":["1792-0981","1792-1015"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and Therapeutic Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3497784791","display_name":null,"funder_award_id":"81202373","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5356002423","display_name":null,"funder_award_id":"2016YFD0500700","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320336567","display_name":"Natural Science Basic Research Program of Shaanxi Province","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2860176197.pdf","grobid_xml":"https://content.openalex.org/works/W2860176197.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1535117461","https://openalex.org/W1966107011","https://openalex.org/W1969894091","https://openalex.org/W1972467459","https://openalex.org/W1977068716","https://openalex.org/W1999138042","https://openalex.org/W2002109952","https://openalex.org/W2038046083","https://openalex.org/W2040299410","https://openalex.org/W2077233112","https://openalex.org/W2117475553","https://openalex.org/W2137378887","https://openalex.org/W2149654746","https://openalex.org/W2150537020","https://openalex.org/W2159988607","https://openalex.org/W2264339884","https://openalex.org/W2272557547","https://openalex.org/W2337909815","https://openalex.org/W2559934092","https://openalex.org/W2562295517","https://openalex.org/W2583351025","https://openalex.org/W2585451190","https://openalex.org/W2603969810","https://openalex.org/W2605497043","https://openalex.org/W2617713330","https://openalex.org/W2619798031","https://openalex.org/W2620785818","https://openalex.org/W2624582564","https://openalex.org/W2734195183","https://openalex.org/W2779167203"],"related_works":["https://openalex.org/W2390988738","https://openalex.org/W1966248592","https://openalex.org/W4294316526","https://openalex.org/W3030377952","https://openalex.org/W2077233112","https://openalex.org/W2067703377","https://openalex.org/W3026643042","https://openalex.org/W2086104594","https://openalex.org/W7172505564","https://openalex.org/W2051238234"],"abstract_inverted_index":{"infection.":[0],"It":[1],"may":[2,179],"be":[3],"useful":[4,182],"to":[5,54,110,193],"screen":[6],"universal":[7],"influenza":[8,45,135,143,172,201],"virus":[9,33,46,62,136,173,202],"vaccines,":[10],"analyzing":[11],"the":[12,18,65,70,84,94,97,114,165,171,190,195,212],"epitopes":[13,95,117,129,178,213],"of":[14,17,24,39,96,102,134,164,200,214],"multiple":[15,79],"subtypes":[16],"hemagglutinin":[19],"(HA)":[20],"protein.":[21,99],"A":[22],"total":[23],"40":[25,40],"monoclonal":[26],"antibodies":[27],"(mAbs)":[28],"previously":[29,50],"obtained":[30],"from":[31,142,146,154],"flu":[32,61],"HA":[34,98,127,174],"antigens":[35],"(development":[36],"and":[37,56,87,108,112,120,149,152,176,197,205],"characterization":[38],"mAbs":[41,58],"generated":[42],"using":[43,64],"H1N1":[44,148],"split":[47],"vaccines":[48],"were":[49,52,76,106,137],"published)":[51],"used":[53,109],"detect":[55],"classify":[57],"into":[59],"distinct":[60],"sub-categories":[63],"ELISA":[66],"method.":[67],"Following":[68],"this,":[69],"common":[71,104],"continuous":[72],"amino":[73],"acid":[74],"sequences":[75,105],"identified":[77],"by":[78],"sequence":[80],"alignment":[81],"analysis":[82],"with":[83],"GenBank":[85],"database":[86],"DNAMAN":[88],"software,":[89],"for":[90,184,210],"use":[91],"in":[92,170],"predicting":[93],"Synthesized":[100],"peptides":[101],"these":[103,124],"prepared,":[107],"verify":[111],"determine":[113],"predicted":[115],"linear":[116,128,177],"through":[118],"localization":[119],"distribution":[121],"analyses.":[122],"With":[123],"methods,":[125],"nine":[126],"distributed":[130],"among":[131],"different":[132],"strains":[133],"identified,":[138],"which":[139],"included":[140],"three":[141],"A,":[144],"four":[145],"2009":[147],"seasonal":[150],"influenza,":[151],"two":[153],"H1.":[155],"The":[156],"present":[157,180],"study":[158,191],"showed":[159],"that":[160],"considering":[161],"a":[162,181,207],"combination":[163],"antigen-antibody":[166],"reaction":[167],"specificity,":[168],"variation":[169],"protein":[175],"approach":[183],"designing":[185],"effective":[186],"multi-epitope":[187],"vaccines.":[188],"Furthermore,":[189],"aimed":[192],"clarify":[194],"cause":[196],"pathogenic":[198,216],"mechanism":[199],"HA-induced":[203],"flu,":[204],"presents":[206],"novel":[208],"idea":[209],"identifying":[211],"other":[215],"microorganisms.":[217]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2018-07-19T00:00:00"}