{"id":"https://openalex.org/W285297413","doi":"https://doi.org/10.1016/j.fitote.2015.05.001","title":"Novel triterpenoid saponins from residual seed cake of Camellia oleifera Abel. show anti-proliferative activity against tumor cells","display_name":"Novel triterpenoid saponins from residual seed cake of Camellia oleifera Abel. show anti-proliferative activity against tumor cells","publication_year":2015,"publication_date":"2015-05-07","ids":{"openalex":"https://openalex.org/W285297413","doi":"https://doi.org/10.1016/j.fitote.2015.05.001","mag":"285297413","pmid":"https://pubmed.ncbi.nlm.nih.gov/25958771"},"language":"en","primary_location":{"id":"doi:10.1016/j.fitote.2015.05.001","doi":"https://doi.org/10.1016/j.fitote.2015.05.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.fitote.2015.05.001","pdf_url":null,"source":{"id":"https://openalex.org/S44811770","display_name":"Fitoterapia","issn_l":"0367-326X","issn":["0367-326X","1873-6971"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fitoterapia","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027268548","display_name":"Jian-Fa Zong","orcid":"https://orcid.org/0000-0002-3480-3720","observed_orcids":["https://orcid.org/0000-0002-3480-3720"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]},{"id":"https://openalex.org/I4405271931","display_name":"State Key Laboratory of Tea Plant Biology and Utilization","ror":"https://ror.org/0398jwk60","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271931"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianfa Zong","raw_affiliation_strings":["State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, PR China"],"raw_orcid":"https://orcid.org/0000-0002-3480-3720","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, PR China","institution_ids":["https://openalex.org/I140221134","https://openalex.org/I4405271931"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119847881","display_name":"Ruilong Wang","orcid":"https://orcid.org/0009-0002-9369-0284","observed_orcids":["https://orcid.org/0009-0002-9369-0284"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]},{"id":"https://openalex.org/I4405271931","display_name":"State Key Laboratory of Tea Plant Biology and Utilization","ror":"https://ror.org/0398jwk60","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271931"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruilong Wang","raw_affiliation_strings":["State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, PR China","institution_ids":["https://openalex.org/I140221134","https://openalex.org/I4405271931"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100759029","display_name":"Guan\u2010Hu Bao","orcid":"https://orcid.org/0000-0003-4336-5678","observed_orcids":["https://orcid.org/0000-0003-4336-5678"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]},{"id":"https://openalex.org/I4405271931","display_name":"State Key Laboratory of Tea Plant Biology and Utilization","ror":"https://ror.org/0398jwk60","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271931"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guanhu Bao","raw_affiliation_strings":["State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, PR China","institution_ids":["https://openalex.org/I140221134","https://openalex.org/I4405271931"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001043047","display_name":"Tie-Jun Ling","orcid":"https://orcid.org/0000-0001-7059-5861","observed_orcids":["https://orcid.org/0000-0001-7059-5861"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]},{"id":"https://openalex.org/I4405271931","display_name":"State Key Laboratory of Tea Plant Biology and Utilization","ror":"https://ror.org/0398jwk60","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271931"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tiejun Ling","raw_affiliation_strings":["State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, PR China","institution_ids":["https://openalex.org/I140221134","https://openalex.org/I4405271931"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100425187","display_name":"Liang Zhang","orcid":"https://orcid.org/0000-0002-2279-2657","observed_orcids":["https://orcid.org/0000-0002-2279-2657","https://orcid.org/0000-0001-7183-1192"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]},{"id":"https://openalex.org/I4405271931","display_name":"State Key Laboratory of Tea Plant Biology and Utilization","ror":"https://ror.org/0398jwk60","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271931"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liang Zhang","raw_affiliation_strings":["State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, PR China","institution_ids":["https://openalex.org/I140221134","https://openalex.org/I4405271931"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102764016","display_name":"Xinfu Zhang","orcid":"https://orcid.org/0000-0003-4813-9418","observed_orcids":["https://orcid.org/0000-0003-4813-9418"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]},{"id":"https://openalex.org/I4405271931","display_name":"State Key Laboratory of Tea Plant Biology and Utilization","ror":"https://ror.org/0398jwk60","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271931"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinfu Zhang","raw_affiliation_strings":["State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, PR China","institution_ids":["https://openalex.org/I140221134","https://openalex.org/I4405271931"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065735846","display_name":"Ruyan Hou","orcid":"https://orcid.org/0000-0003-4423-694X","observed_orcids":["https://orcid.org/0000-0003-4423-694X"]},"institutions":[{"id":"https://openalex.org/I140221134","display_name":"Anhui Agricultural University","ror":"https://ror.org/0327f3359","country_code":"CN","type":"education","lineage":["https://openalex.org/I140221134"]},{"id":"https://openalex.org/I4405271931","display_name":"State Key Laboratory of Tea Plant Biology and Utilization","ror":"https://ror.org/0398jwk60","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271931"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ruyan Hou","raw_affiliation_strings":["State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, PR China. Electronic address: hry@ahau.edu.cn","State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei, 230036, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei 230036, PR China. Electronic address: hry@ahau.edu.cn","institution_ids":["https://openalex.org/I140221134","https://openalex.org/I4405271931"]},{"raw_affiliation_string":"State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei, 230036, PR China","institution_ids":["https://openalex.org/I140221134","https://openalex.org/I4405271931"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5065735846"],"corresponding_institution_ids":["https://openalex.org/I140221134","https://openalex.org/I4405271931"],"apc_list":{"value":3950,"currency":"USD","value_usd":3950},"apc_paid":null,"fwci":3.8141,"has_fulltext":false,"cited_by_count":85,"citation_normalized_percentile":{"value":0.93854265,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"104","issue":null,"first_page":"7","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11385","display_name":"Natural product bioactivities and synthesis","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11385","display_name":"Natural product bioactivities and synthesis","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12215","display_name":"Phytochemical Studies and Bioactivities","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12685","display_name":"Phytochemical compounds biological activities","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/triterpenoid-saponins","display_name":"triterpenoid saponins","score":0.9390000104904175},{"id":"https://openalex.org/keywords/oleanane-type-saponins","display_name":"oleanane saponins","score":0.828000009059906},{"id":"https://openalex.org/keywords/camellia-oleifera","display_name":"Camellia oleifera","score":0.9919999837875366},{"id":"https://openalex.org/keywords/oil-cake","display_name":"oil cake","score":0.7649999856948853},{"id":"https://openalex.org/keywords/antiproliferative-activity","display_name":"antiproliferative activity","score":0.7929999828338623},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.9810000061988831},{"id":"https://openalex.org/keywords/human-cancer-cell-lines","display_name":"human cancer cell lines","score":0.8970000147819519},{"id":"https://openalex.org/keywords/structure-elucidation","display_name":"structure elucidation","score":0.7279999852180481}],"concepts":[{"id":"https://openalex.org/C107585567","wikidata":"https://www.wikidata.org/wiki/Q2915788","display_name":"Triterpenoid","level":2,"score":0.7895073890686035},{"id":"https://openalex.org/C2778153387","wikidata":"https://www.wikidata.org/wiki/Q2498293","display_name":"Camellia oleifera","level":2,"score":0.7653795480728149},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.6290394067764282},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6218046545982361},{"id":"https://openalex.org/C194671627","wikidata":"https://www.wikidata.org/wiki/Q192639","display_name":"Glycoside","level":2,"score":0.49780821800231934},{"id":"https://openalex.org/C2779230187","wikidata":"https://www.wikidata.org/wiki/Q1924527","display_name":"Oleanane","level":4,"score":0.4817200303077698},{"id":"https://openalex.org/C3020616263","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Tumor cells","level":2,"score":0.4303184747695923},{"id":"https://openalex.org/C2778564307","wikidata":"https://www.wikidata.org/wiki/Q207653","display_name":"Saponin","level":3,"score":0.4174802005290985},{"id":"https://openalex.org/C2780527577","wikidata":"https://www.wikidata.org/wiki/Q2915788","display_name":"Triterpene","level":3,"score":0.3443530201911926},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23663750290870667},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2311272919178009},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.05730882287025452},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000972","descriptor_name":"Antineoplastic Agents, Phytogenic","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D000972","descriptor_name":"Antineoplastic Agents, Phytogenic","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009828","descriptor_name":"Oleanolic Acid","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D009828","descriptor_name":"Oleanolic Acid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012503","descriptor_name":"Saponins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D012503","descriptor_name":"Saponins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012639","descriptor_name":"Seeds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D014315","descriptor_name":"Triterpenes","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D014315","descriptor_name":"Triterpenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D028244","descriptor_name":"Camellia","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.fitote.2015.05.001","doi":"https://doi.org/10.1016/j.fitote.2015.05.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.fitote.2015.05.001","pdf_url":null,"source":{"id":"https://openalex.org/S44811770","display_name":"Fitoterapia","issn_l":"0367-326X","issn":["0367-326X","1873-6971"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fitoterapia","raw_type":"journal-article"},{"id":"pmid:25958771","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25958771","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fitoterapia","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1528811583","https://openalex.org/W1969641220","https://openalex.org/W1982398135","https://openalex.org/W1997557556","https://openalex.org/W2010491625","https://openalex.org/W2022450300","https://openalex.org/W2032019731","https://openalex.org/W2039744784","https://openalex.org/W2042665179","https://openalex.org/W2044104519","https://openalex.org/W2052439775","https://openalex.org/W2056525414","https://openalex.org/W2073378630","https://openalex.org/W2081395694","https://openalex.org/W2081746815","https://openalex.org/W2088564894","https://openalex.org/W2095033878","https://openalex.org/W2114487979","https://openalex.org/W2158554606","https://openalex.org/W2161040986","https://openalex.org/W2320485968","https://openalex.org/W2325482171","https://openalex.org/W2338773981","https://openalex.org/W2390299019"],"related_works":["https://openalex.org/W2261555685","https://openalex.org/W1997557556","https://openalex.org/W2759163049","https://openalex.org/W6976681870","https://openalex.org/W2029744357","https://openalex.org/W1134621021","https://openalex.org/W6977284741","https://openalex.org/W2332642877","https://openalex.org/W2320485968","https://openalex.org/W4408361445"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":14},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}