{"id":"https://openalex.org/W284172196","doi":null,"title":"A temporal study of the lesions induced by MoMuSV-349.","display_name":"A temporal study of the lesions induced by MoMuSV-349.","publication_year":1993,"publication_date":"1993-12-01","ids":{"openalex":"https://openalex.org/W284172196","mag":"284172196","pmid":"https://pubmed.ncbi.nlm.nih.gov/8292554","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2002254"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:2284029","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2002254","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2002254","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066462648","display_name":"R J Hoffman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115475287","display_name":"Oklahoma State University","ror":"https://ror.org/01g9vbr38","country_code":"US","type":"education","lineage":["https://openalex.org/I115475287"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R J Hoffman","raw_affiliation_strings":["Department of Veterinary Pathology, Oklahoma State University, College of Veterinary Medicine, Stillwater"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Pathology, Oklahoma State University, College of Veterinary Medicine, Stillwater","institution_ids":["https://openalex.org/I115475287"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076613159","display_name":"George Stoica","orcid":"https://orcid.org/0000-0001-8071-4828","observed_orcids":["https://orcid.org/0000-0001-8071-4828"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Stoica","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"74","issue":"6","first_page":"561","last_page":"72"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.6669999957084656,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.6669999957084656,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.259799987077713,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13385","display_name":"Infectious Diseases and Mycology","score":0.021700000390410423,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retroviral-oncogenesis","display_name":"retroviral oncogenesis","score":0.5419999957084656},{"id":"https://openalex.org/keywords/angiosarcoma","display_name":"angiosarcoma","score":0.7269999980926514},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.8460000157356262},{"id":"https://openalex.org/keywords/neutrophilia","display_name":"neutrophilia","score":0.8579999804496765},{"id":"https://openalex.org/keywords/lymphopenia","display_name":"lymphopenia","score":0.9980000257492065},{"id":"https://openalex.org/keywords/anemia","display_name":"anemia","score":0.9559999704360962},{"id":"https://openalex.org/keywords/thymic-atrophy","display_name":"thymic atrophy","score":0.878000020980835},{"id":"https://openalex.org/keywords/pulmonary-hemorrhage","display_name":"pulmonary hemorrhage","score":0.9909999966621399},{"id":"https://openalex.org/keywords/rhabdomyosarcoma","display_name":"rhabdomyosarcoma","score":0.9639999866485596},{"id":"https://openalex.org/keywords/cachexia","display_name":"cachexia","score":0.9739999771118164},{"id":"https://openalex.org/keywords/balb-c-mice","display_name":"BALB/c mice","score":0.7160000205039978},{"id":"https://openalex.org/keywords/tumor-vascularity","display_name":"tumor vascularity","score":0.550000011920929}],"concepts":[{"id":"https://openalex.org/C2777802486","wikidata":"https://www.wikidata.org/wiki/Q491741","display_name":"Neutrophilia","level":2,"score":0.827919065952301},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.7595226764678955},{"id":"https://openalex.org/C2777704314","wikidata":"https://www.wikidata.org/wiki/Q6003455","display_name":"Cachexia","level":3,"score":0.6881037950515747},{"id":"https://openalex.org/C2781172350","wikidata":"https://www.wikidata.org/wiki/Q194520","display_name":"Atrophy","level":2,"score":0.5119715929031372},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.47042274475097656},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.4520943760871887},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.4362002909183502},{"id":"https://openalex.org/C2780635560","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Neoplasm","level":2,"score":0.42603451013565063},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36738818883895874},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.16995474696159363},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16629332304000854}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006394","descriptor_name":"Hemangiosarcoma","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006394","descriptor_name":"Hemangiosarcoma","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008980","descriptor_name":"Moloney murine sarcoma virus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012192","descriptor_name":"Retroviridae Infections","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012192","descriptor_name":"Retroviridae Infections","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012513","descriptor_name":"Sarcoma, Experimental","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012513","descriptor_name":"Sarcoma, Experimental","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013950","descriptor_name":"Thymus Gland","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014412","descriptor_name":"Tumor Virus Infections","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014412","descriptor_name":"Tumor Virus Infections","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:2284029","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2002254","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:8292554","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8292554","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of experimental pathology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2002254","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2002254/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Exp Pathol","raw_type":"Text"},{"id":"mag:284172196","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8292554","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2284029","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2002254","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W183020029","https://openalex.org/W261985658","https://openalex.org/W1550738411","https://openalex.org/W1871141908","https://openalex.org/W1997605512","https://openalex.org/W2012813456","https://openalex.org/W2013521378","https://openalex.org/W2017638565","https://openalex.org/W2057460752","https://openalex.org/W2062741382","https://openalex.org/W2079473945","https://openalex.org/W2095342718","https://openalex.org/W2124312551","https://openalex.org/W2143990736","https://openalex.org/W2400389642"],"related_works":["https://openalex.org/W2400389642","https://openalex.org/W261985658","https://openalex.org/W7039643706","https://openalex.org/W2004228634","https://openalex.org/W2129133543","https://openalex.org/W2143990736","https://openalex.org/W2132901691","https://openalex.org/W2337225880","https://openalex.org/W2345196253","https://openalex.org/W2117117015"],"abstract_inverted_index":{"We":[0],"used":[1],"time":[2],"point":[3],"studies":[4],"to":[5,87,169],"document":[6],"the":[7,72,78,82,138,180,185,191],"progression":[8],"of":[9,46,54,71,81,187],"neoplasms,":[10],"haematologic":[11,221],"abnormalities":[12],"and":[13,56,152,166,201,203,219,222],"associated":[14,63,103],"lesions":[15,33],"induced":[16,211],"by":[17,44,216],"Moloney":[18],"murine":[19],"sarcoma":[20],"virus-349":[21],"(MoMuSV-349).":[22],"BALB/c":[23],"mice":[24,94,124],"inoculated":[25,195],"intraperitoneally":[26],"with":[27,64,104,196],"MoMuSV-349":[28,65,197,210],"first":[29],"developed":[30,198],"histologically":[31,167],"discernible":[32],"at":[34,90,96,112,172],"14":[35,91],"days":[36],"post-inoculation":[37],"(d.p.i.).":[38],"The":[39,69],"initial":[40],"neoplasms":[41,73,110,139,213],"were":[42,67,156,163],"characterized":[43,215],"whorls":[45],"fusiform":[47],"or":[48],"spindle-shaped":[49],"cells":[50],"enmeshing":[51],"dense":[52],"infiltrates":[53],"neutrophils":[55],"macrophages.":[57],"By":[58,120],"21":[59],"d.p.i.,":[60,122],"clinical":[61,101,127],"signs":[62,102,128],"infection":[66],"evident.":[68],"distribution":[70],"was":[74,84,184],"more":[75],"widespread,":[76],"although":[77],"histologic":[79],"appearance":[80],"tumours":[83],"very":[85],"similar":[86,168],"that":[88,209],"found":[89,178],"d.p.i.":[92,98,114,162,174,182],"All":[93],"sacrificed":[95,160,171],"28":[97,113],"exhibited":[99,125],"characteristic":[100],"MoMuSV-349,":[105],"including":[106],"moderate":[107,204],"cachexia.":[108],"Histologically,":[109,136],"observed":[111],"contained":[115],"a":[116,141],"significant":[117],"vascular":[118,143],"component.":[119,144],"35":[121,173],"all":[123,137],"severe":[126,149,199,220],"(e.g.":[129],"cachexia,":[130],"dull":[131],"hair":[132],"coat,":[133],"uneven":[134],"gait).":[135],"had":[140],"predominant":[142],"Non-neoplastic":[145],"lesions,":[146],"such":[147],"as":[148],"thymic":[150],"atrophy":[151],"multifocal":[153],"pulmonary":[154],"haemorrhage,":[155],"commonly":[157],"present.":[158],"Mice":[159,194],"42":[161,181],"clinically,":[164],"grossly":[165],"those":[170],"However,":[175],"one":[176],"difference":[177],"in":[179],"group":[183],"presence":[186],"rare":[188],"rhabdomyosarcomas":[189],"infiltrating":[190],"skeletal":[192],"muscles.":[193],"neutrophilia":[200],"lymphopenia,":[202],"anaemia.":[205],"This":[206],"study":[207],"demonstrates":[208],"angiosarcomatous":[212],"are":[214],"stage":[217],"development":[218],"non-neoplastic":[223],"abnormalities.":[224]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}