{"id":"https://openalex.org/W2833715563","doi":null,"title":"Pentraxin 3 and biopsy status in celiac patients.","display_name":"Pentraxin 3 and biopsy status in celiac patients.","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2833715563","mag":"2833715563","pmid":"https://pubmed.ncbi.nlm.nih.gov/30013746","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6040031"},"language":"en","primary_location":{"id":"pmh:oai:journals.sbmu.ac.ir/ghfbb:article/1186","doi":null,"is_oa":true,"landing_page_url":"https://journals.sbmu.ac.ir/ghfbb/index.php/ghfbb/article/view/1186","pdf_url":"https://journals.sbmu.ac.ir/ghfbb/index.php/ghfbb/article/download/1186/798","source":{"id":"https://openalex.org/S2764627315","display_name":"Gastroenterology and hepatology from bed to bench.","issn_l":"2008-2258","issn":["2008-2258","2008-4234"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319135","host_organization_name":"Shahid Beheshti University of Medical Sciences","host_organization_lineage":["https://openalex.org/P4310319135"],"host_organization_lineage_names":["Shahid Beheshti University of Medical Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008-2258","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://journals.sbmu.ac.ir/ghfbb/index.php/ghfbb/article/download/1186/798","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012181156","display_name":"Roberto Assandri","orcid":"https://orcid.org/0000-0002-2278-3902","observed_orcids":["https://orcid.org/0000-0002-2278-3902"]},"institutions":[{"id":"https://openalex.org/I4210144922","display_name":"Azienda Ospedaliera Ospedale Maggiore","ror":"https://ror.org/04svedz43","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210144922"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Roberto Assandri","raw_affiliation_strings":["Departement of Clinical Pathology, Clinical Chemistry Laboratory ASST Ospedale Maggiore di Crema, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departement of Clinical Pathology, Clinical Chemistry Laboratory ASST Ospedale Maggiore di Crema, Italy","institution_ids":["https://openalex.org/I4210144922"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039467116","display_name":"Alessandro Montanelli","orcid":"https://orcid.org/0000-0002-4426-6906","observed_orcids":["https://orcid.org/0000-0002-4426-6906"]},"institutions":[{"id":"https://openalex.org/I4210103289","display_name":"Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia","ror":"https://ror.org/015rhss58","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210103289"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessandro Montanelli","raw_affiliation_strings":["Clinical Chemistry Laboratory, Spedali Civili di Brescia, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Chemistry Laboratory, Spedali Civili di Brescia, Italy","institution_ids":["https://openalex.org/I4210103289"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1977,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.51961405,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"11","issue":"3","first_page":"225","last_page":"232"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11348","display_name":"Celiac Disease Research and Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11348","display_name":"Celiac Disease Research and Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14245","display_name":"Biomarkers in Disease Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pentraxin-3","display_name":"pentraxin 3","score":0.9940000176429749},{"id":"https://openalex.org/keywords/celiac-disease","display_name":"celiac disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anti-gliadin-antibodies","display_name":"anti-gliadin antibodies","score":0.8209999799728394},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.7879999876022339},{"id":"https://openalex.org/keywords/gluten-sensitivity","display_name":"gluten sensitivity","score":0.6570000052452087},{"id":"https://openalex.org/keywords/intestinal-injury","display_name":"intestinal injury","score":0.699999988079071},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.5580000281333923}],"concepts":[{"id":"https://openalex.org/C178498320","wikidata":"https://www.wikidata.org/wiki/Q14903608","display_name":"Tissue transglutaminase","level":3,"score":0.6889476776123047},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6424834728240967},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6104062795639038},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5960605144500732},{"id":"https://openalex.org/C2778426112","wikidata":"https://www.wikidata.org/wiki/Q3055380","display_name":"Enteropathy","level":3,"score":0.5590088963508606},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.4623168110847473},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4316595196723938},{"id":"https://openalex.org/C127901578","wikidata":"https://www.wikidata.org/wiki/Q21120502","display_name":"PTX3","level":3,"score":0.4137204885482788},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4054926633834839},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.39977550506591797},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.3785618543624878},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3675854802131653},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1376972496509552},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:journals.sbmu.ac.ir/ghfbb:article/1186","doi":null,"is_oa":true,"landing_page_url":"https://journals.sbmu.ac.ir/ghfbb/index.php/ghfbb/article/view/1186","pdf_url":"https://journals.sbmu.ac.ir/ghfbb/index.php/ghfbb/article/download/1186/798","source":{"id":"https://openalex.org/S2764627315","display_name":"Gastroenterology and hepatology from bed to bench.","issn_l":"2008-2258","issn":["2008-2258","2008-4234"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319135","host_organization_name":"Shahid Beheshti University of Medical Sciences","host_organization_lineage":["https://openalex.org/P4310319135"],"host_organization_lineage_names":["Shahid Beheshti University of Medical Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008-2258","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:europepmc.org:4999587","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6040031","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:30013746","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30013746","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology and hepatology from bed to bench","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6040031","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6040031/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterol Hepatol Bed Bench","raw_type":"Text"},{"id":"mag:2833715563","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30013746","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:journals.sbmu.ac.ir/ghfbb:article/1186","doi":null,"is_oa":true,"landing_page_url":"https://journals.sbmu.ac.ir/ghfbb/index.php/ghfbb/article/view/1186","pdf_url":"https://journals.sbmu.ac.ir/ghfbb/index.php/ghfbb/article/download/1186/798","source":{"id":"https://openalex.org/S2764627315","display_name":"Gastroenterology and hepatology from bed to bench.","issn_l":"2008-2258","issn":["2008-2258","2008-4234"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319135","host_organization_name":"Shahid Beheshti University of Medical Sciences","host_organization_lineage":["https://openalex.org/P4310319135"],"host_organization_lineage_names":["Shahid Beheshti University of Medical Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008-2258","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2833715563.pdf","grobid_xml":"https://content.openalex.org/works/W2833715563.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1541423869","https://openalex.org/W1559564651","https://openalex.org/W1902709718","https://openalex.org/W1923128715","https://openalex.org/W1968014632","https://openalex.org/W1968214100","https://openalex.org/W1969592211","https://openalex.org/W1984060274","https://openalex.org/W1994808474","https://openalex.org/W1998220340","https://openalex.org/W2030602908","https://openalex.org/W2034523392","https://openalex.org/W2048858087","https://openalex.org/W2052235824","https://openalex.org/W2066083984","https://openalex.org/W2075218891","https://openalex.org/W2078710292","https://openalex.org/W2079531926","https://openalex.org/W2079683856","https://openalex.org/W2090205875","https://openalex.org/W2110878879","https://openalex.org/W2121427646","https://openalex.org/W2134132651","https://openalex.org/W2135648252","https://openalex.org/W2141305069","https://openalex.org/W2149186741","https://openalex.org/W2160125610","https://openalex.org/W2165428460","https://openalex.org/W2183309348","https://openalex.org/W3134084687","https://openalex.org/W4252328505"],"related_works":["https://openalex.org/W2134132651","https://openalex.org/W3033295202","https://openalex.org/W2012871079","https://openalex.org/W2036802428","https://openalex.org/W7218223572","https://openalex.org/W2612059410","https://openalex.org/W7128478353","https://openalex.org/W2116494809","https://openalex.org/W2346951180","https://openalex.org/W1968062436"],"abstract_inverted_index":{"AIM:":[0],"In":[1],"our":[2],"study":[3],"we":[4],"explored":[5],"a":[6,19,32,120,145,205],"possible":[7],"relationship":[8],"between":[9,177],"PTX3":[10,157,178,195,203,220,245,255],"and":[11,35,54,63,75,134,181,267],"CD.":[12],"BACKGROUND:":[13],"Gluten":[14],"sensitivity":[15],"is":[16,55,204,256],"known":[17,121,146],"as":[18,48,50,155],"hallmark":[20],"of":[21,27,31,60,77,123,148,207,211,232],"celiac":[22],"disease":[23,227],"(CD).":[24],"The":[25,41,80],"diagnosis":[26],"CD":[28,42,98,124,149,266],"requires":[29],"demonstration":[30],"typical":[33],"enteropathy,":[34],"positive":[36],"serology":[37],"supports":[38],"the":[39,46,51,58,71,208,212,260,271],"diagnosis.":[40],"immune":[43,214,273],"response":[44,262],"involves":[45],"adaptive,":[47],"well":[49],"innate":[52,94,213,261],"immunity":[53],"characterized":[56],"by":[57,162],"presence":[59],"anti-gliadin":[61],"(AGA)":[62],"anti-transglutaminase":[64],"2":[65],"antibodies":[66],"(tTGA),":[67],"lymphocytic":[68],"infiltration":[69],"in":[70,93,111,225,265],"intestinal":[72],"epithelial":[73],"membrane":[74],"expression":[76],"multiple":[78],"cytokines.":[79],"long":[81],"pentraxin":[82],"3":[83],"(PTX3),":[84],"an":[85,90,166],"acute-phase":[86],"inflammatory":[87],"molecule,":[88],"plays":[89],"important":[91],"role":[92],"immunity.":[95],"METHODS:":[96],"108":[97],"patients":[99,118,228,238],"were":[100,160,175,223],"divided":[101],"according":[102],"to":[103,249,258,263],"Marsh":[104,108,116,135,139],"Histological":[105],"grade":[106],"following":[107],"criteria":[109],"classification":[110],"three":[112],"groups:":[113],"Group":[114,131,137],"1:":[115],"0,":[117],"with":[119,197,229,239],"history":[122,147],"under":[125],"gluten":[126],"free":[127],"diet,":[128],"complete":[129],"remission;":[130],"2:":[132],"Marsh1":[133],"2;":[136],"3:":[138],"3.":[140],"Healthy":[141],"age-matched":[142],"controls":[143],"without":[144],"or":[150],"gastrointestinal":[151,199],"symptoms":[152],"(n=30)":[153],"served":[154],"controls.":[156],"serum":[158,179,221,246],"levels":[159,180,183,222,231,243,247],"measured":[161],"sandwich":[163],"ELISA":[164],"on":[165],"automated":[167],"platform.":[168],"RESULTS:":[169],"<":[170],"0.005)":[171],"but":[172],"no":[173],"correlations":[174],"detected":[176],"tTGA":[182],"(group":[184],"2,":[185],"r=":[186],"0.04;":[187],"group":[188],"3,":[189],"r=0.24).":[190],"Serological":[191],"data":[192,217],"revealed":[193],"that":[194,219,237,254],"correlated":[196],"major":[198],"damage":[200],"patients.":[201],"CONCLUSION:":[202],"component":[206],"humoral":[209],"arm":[210],"system.":[215],"Our":[216],"showed":[218],"high":[224],"active":[226],"pathological":[230],"AGA.":[233],"We":[234,252],"also":[235],"demonstrated":[236],"normal":[240],"AGA":[241],"IgA":[242],"had":[244],"compared":[248],"healthy":[250],"control.":[251],"hypothesized":[253],"able":[257],"modulate":[259],"gliadin":[264],"it":[268],"could":[269],"regulate":[270],"adaptive":[272],"response.":[274]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-07-19T00:00:00"}