{"id":"https://openalex.org/W282995849","doi":null,"title":"Stimulation of the Immune Response by Herbal Formulas for Taeeumin","display_name":"Stimulation of the Immune Response by Herbal Formulas for Taeeumin","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W282995849","mag":"282995849"},"language":"en","primary_location":{"id":"mag:282995849","doi":null,"is_oa":false,"landing_page_url":"http://www.koreascience.or.kr/article/ArticleFullRecord.jsp?cn=HSSSBH_2010_v22n3_141","pdf_url":null,"source":{"id":"https://openalex.org/S2913130013","display_name":"Journal of Sasang Constitutional Medicine","issn_l":"1226-4075","issn":["1226-4075","2287-786X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["kci-registered"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Sasang Constitutional Medicine","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065464212","display_name":"Da-Young Jung","orcid":"https://orcid.org/0000-0002-1203-3737","observed_orcids":["https://orcid.org/0000-0002-1203-3737"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Da-Young Jung","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1203-3737","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040834500","display_name":"Hyekyung Ha","orcid":"https://orcid.org/0000-0002-7326-6366","observed_orcids":["https://orcid.org/0000-0002-7326-6366"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hyekyung Ha","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7326-6366","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100413521","display_name":"Ho\u2010Young Lee","orcid":"https://orcid.org/0000-0001-7556-9312","observed_orcids":["https://orcid.org/0000-0001-7556-9312","https://orcid.org/0000-0002-5756-7169"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ho\u2010Young Lee","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7556-9312","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103152655","display_name":"Jin\u2010Ah Lee","orcid":"https://orcid.org/0000-0002-1178-1557","observed_orcids":["https://orcid.org/0000-0002-1178-1557","https://orcid.org/0009-0001-4434-8055"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jin\u2010Ah Lee","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1178-1557","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012074831","display_name":"Namhun Lee","orcid":"https://orcid.org/0000-0002-5039-2423","observed_orcids":["https://orcid.org/0000-0002-5039-2423"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Namhun Lee","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5039-2423","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068704502","display_name":"Jun\u2010Kyoung Lee","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jun\u2010Kyoung Lee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042646799","display_name":"Dae-Sun Huang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dae-Sun Huang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5072379969","display_name":"Hyeun\u2010Kyoo Shin","orcid":"https://orcid.org/0000-0003-2319-6678","observed_orcids":["https://orcid.org/0000-0003-2319-6678"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hyeun\u2010Kyoo Shin","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2319-6678","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"22","issue":"3","first_page":"141","last_page":"151"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.24879999458789825,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.24879999458789825,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13919","display_name":"Medicinal plant effects and applications","score":0.16439999639987946,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12298","display_name":"Phytochemicals and Medicinal Plants","score":0.08259999752044678,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/taeeumin","display_name":"Taeeumin","score":0.8389999866485596},{"id":"https://openalex.org/keywords/herbal-formula","display_name":"herbal formula","score":0.925000011920929},{"id":"https://openalex.org/keywords/immunostimulation","display_name":"immunostimulation","score":0.7070000171661377},{"id":"https://openalex.org/keywords/splenocyte-proliferation","display_name":"splenocyte proliferation","score":0.8629999756813049},{"id":"https://openalex.org/keywords/nitric-oxide-production","display_name":"nitric oxide production","score":0.8500000238418579},{"id":"https://openalex.org/keywords/raw-264-7-macrophages","display_name":"RAW 264.7 macrophages","score":0.9850000143051147},{"id":"https://openalex.org/keywords/sasang-constitutional-medicine","display_name":"Sasang constitutional medicine","score":0.8230000138282776},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.6539999842643738}],"concepts":[{"id":"https://openalex.org/C189976730","wikidata":"https://www.wikidata.org/wiki/Q3493700","display_name":"Splenocyte","level":3,"score":0.8316339254379272},{"id":"https://openalex.org/C2776946954","wikidata":"https://www.wikidata.org/wiki/Q420291","display_name":"Ovalbumin","level":3,"score":0.8123247027397156},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6682689189910889},{"id":"https://openalex.org/C2780924562","wikidata":"https://www.wikidata.org/wiki/Q190527","display_name":"Alum","level":2,"score":0.6431618928909302},{"id":"https://openalex.org/C19869320","wikidata":"https://www.wikidata.org/wiki/Q419277","display_name":"Concanavalin A","level":3,"score":0.6415706276893616},{"id":"https://openalex.org/C2778754761","wikidata":"https://www.wikidata.org/wiki/Q421804","display_name":"Lipopolysaccharide","level":2,"score":0.5753398537635803},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5160772204399109},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.5149303078651428},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45739707350730896},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.44695812463760376},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.41433730721473694},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.40505433082580566},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2791304290294647},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.23265933990478516},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1491972804069519},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:282995849","doi":null,"is_oa":false,"landing_page_url":"http://www.koreascience.or.kr/article/ArticleFullRecord.jsp?cn=HSSSBH_2010_v22n3_141","pdf_url":null,"source":{"id":"https://openalex.org/S2913130013","display_name":"Journal of Sasang Constitutional Medicine","issn_l":"1226-4075","issn":["1226-4075","2287-786X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["kci-registered"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Sasang Constitutional Medicine","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W230343487","https://openalex.org/W273231438","https://openalex.org/W778959059","https://openalex.org/W784587206","https://openalex.org/W794893393","https://openalex.org/W810651657","https://openalex.org/W835358975","https://openalex.org/W838677839","https://openalex.org/W1509091993","https://openalex.org/W1528112449","https://openalex.org/W1739247159","https://openalex.org/W1970318694","https://openalex.org/W2010310943","https://openalex.org/W2044145084","https://openalex.org/W2056537467","https://openalex.org/W2074222727","https://openalex.org/W2149764521","https://openalex.org/W2408061003"],"related_works":["https://openalex.org/W1501082941","https://openalex.org/W2157618738","https://openalex.org/W886659071","https://openalex.org/W2304422818","https://openalex.org/W3009629104","https://openalex.org/W773956975","https://openalex.org/W2994427443","https://openalex.org/W2035622423","https://openalex.org/W2610475572","https://openalex.org/W2041805756"],"abstract_inverted_index":{"Abstract":[0],"Stimulation":[1],"of":[2,37,151,227],"the":[3,57,152,210],"Immune":[4],"Response":[5],"by":[6,181],"Herbal":[7],"Formulas":[8],"for":[9,51,128,195,220],"Taeeu":[10],"min":[11],"Da":[12],"Young":[13],"Jung,":[14],"Hyekyung":[15],"Ha,":[16],"Ho-Young":[17],"Lee,":[18,20,22,25],"Jin-Ah":[19],"Nam-Hun":[21],"Jun":[23],"Kyoung":[24],"Dae":[26],"Sun":[27],"Huang,":[28],"Hyeun-Kyoo":[29],"ShinHerbal":[30],"Medicine":[31],"EBM":[32],"Research":[33],"Center,":[34],"Korea":[35,42],"Institute":[36],"Oriental":[38],"Medicine,":[39],"Daejeon,":[40],"305-811,":[41],"1.":[43,133],"ObjectivesThree":[44],"herbal":[45,101,121,175,193,218],"formulas":[46,122,176,194,219],"(Yuldahanso-tang,":[47],"Chungsimyonja-tang,":[48],"and":[49,74,92,118,140,147,155,165,183,204],"Taeeumjowi-tang)":[50],"Taeeumin":[52,196,221],"were":[53,105,123,161],"applied":[54],"to":[55,99,125],"investigate":[56],"immunological":[58],"activities":[59],"on":[60,114],"antigen":[61],"(Ag)-specific":[62],"or":[63],"Ag-non-specific":[64],"immune":[65,228],"responses":[66],"in":[67,83,88,95,159,170,186],"murine":[68],"macrophage":[69],"cell":[70],"line":[71],"(RAW":[72],"264.7)":[73],"ovalbumin":[75],"(OVA)-immunized":[76],"mice.2.":[77],"MethodsThis":[78],"study":[79],"was":[80],"carried":[81],"out":[82],"nitric":[84],"oxide":[85],"(NO)":[86],"synthesis":[87,169],"RAW":[89,171],"264.7":[90,172],"cells":[91],"cellular":[93,179],"proliferation":[94,146,180],"mouse":[96],"splenocytes":[97,187],"according":[98],"three":[100,217],"formulas.":[102],"C57BL/6":[103],"mice":[104,126,190],"immunized":[106],"intraperitonially":[107],"with":[108,209],"OVA/":[109],"aluminium":[110],"(100":[111],"\u338d/200":[112],"\u338d/mouse)":[113],"day":[115,132,135],"1,":[116],"8,":[117],"15.":[119],"Three":[120,174,192],"administrated":[124],"orally":[127],"3":[129],"weeks":[130],"from":[131,188],"On":[134],"22,":[136],"OVA-,":[137],"lipopolysaccharide":[138],"(LPS)-,":[139],"concanavalin":[141],"A":[142,185],"(Con":[143],"A)-stimulated":[144],"splenocyte":[145],"antibodies":[148,150],"(OVA-specific":[149],"IgG,":[153,202],"IgG1,":[154,203],"total":[156,205],"IgM":[157,206],"classes)":[158],"plasma":[160,200],"measured.":[162],"3.":[163],"ResultsYuldahanso-tang":[164],"Chungsimyonja-tang":[166],"increased":[167],"NO":[168],"cells.":[173],"significantly":[177,198],"enhanced":[178,199],"LPS":[182],"Con":[184],"OVA-immunized":[189],"(p<.001).":[191],"also":[197],"OVA-specific":[201],"levels":[207],"compared":[208],"OVA/Alum":[211],"group.4.":[212],"ConclusionThese":[213],"results":[214],"suggested":[215],"that":[216],"could":[222],"be":[223],"used":[224],"as":[225],"stimulator":[226],"response.Key":[229],"Words:":[230]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}