{"id":"https://openalex.org/W28299142","doi":"https://doi.org/10.4049/jimmunol.186.supp.147.27","title":"Characterization of mast cell-dendritic cell interactions (147.27)","display_name":"Characterization of mast cell-dendritic cell interactions (147.27)","publication_year":2011,"publication_date":"2011-04-01","ids":{"openalex":"https://openalex.org/W28299142","doi":"https://doi.org/10.4049/jimmunol.186.supp.147.27","mag":"28299142"},"language":"en","primary_location":{"id":"doi:10.4049/jimmunol.186.supp.147.27","doi":"https://doi.org/10.4049/jimmunol.186.supp.147.27","is_oa":false,"landing_page_url":"https://doi.org/10.4049/jimmunol.186.supp.147.27","pdf_url":null,"source":{"id":"https://openalex.org/S38008053","display_name":"The Journal of Immunology","issn_l":"0022-1767","issn":["0022-1767","1550-6606"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-2","ki-jl-2","medline","norway-2"],"host_organization":"https://openalex.org/P4320800377","host_organization_name":"American Association of Immunologists","host_organization_lineage":["https://openalex.org/P4320800377"],"host_organization_lineage_names":["American Association of Immunologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Immunology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077639805","display_name":"Amanda Carroll\u2010Portillo","orcid":"https://orcid.org/0000-0001-9089-2601","observed_orcids":["https://orcid.org/0000-0001-9089-2601"]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amanda Carroll-Portillo","raw_affiliation_strings":["University of New Mexico , Albuquerque, NM","1University of New Mexico, Albuquerque, NM"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of New Mexico , Albuquerque, NM","institution_ids":["https://openalex.org/I169521973"]},{"raw_affiliation_string":"1University of New Mexico, Albuquerque, NM","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050803031","display_name":"Yuko Kawakami","orcid":"https://orcid.org/0000-0002-4703-350X","observed_orcids":["https://orcid.org/0000-0002-4703-350X"]},"institutions":[{"id":"https://openalex.org/I1311191458","display_name":"La Jolla Institute for Immunology","ror":"https://ror.org/05vkpd318","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1311191458"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuko Kawakami","raw_affiliation_strings":["La Jolla Inst. for Allergy and Immunol. , San Diego, CA","2La Jolla Inst. for Allergy and Immunol., San Diego, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"La Jolla Inst. for Allergy and Immunol. , San Diego, CA","institution_ids":["https://openalex.org/I1311191458"]},{"raw_affiliation_string":"2La Jolla Inst. for Allergy and Immunol., San Diego, CA","institution_ids":["https://openalex.org/I1311191458"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024904153","display_name":"Toshi Kawakami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1311191458","display_name":"La Jolla Institute for Immunology","ror":"https://ror.org/05vkpd318","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1311191458"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Toshi Kawakami","raw_affiliation_strings":["La Jolla Inst. for Allergy and Immunol. , San Diego, CA","2La Jolla Inst. for Allergy and Immunol., San Diego, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"La Jolla Inst. for Allergy and Immunol. , San Diego, CA","institution_ids":["https://openalex.org/I1311191458"]},{"raw_affiliation_string":"2La Jolla Inst. for Allergy and Immunol., San Diego, CA","institution_ids":["https://openalex.org/I1311191458"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054940822","display_name":"Alessandra Cambi","orcid":"https://orcid.org/0000-0003-1597-1582","observed_orcids":["https://orcid.org/0000-0003-1597-1582"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alessandra Cambi","raw_affiliation_strings":["Nijmegen Center for Molecular Life Sciences , Nijmegen ,","3Nijmegen Center for Molecular Life Sciences, Nijmegen, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nijmegen Center for Molecular Life Sciences , Nijmegen ,","institution_ids":[]},{"raw_affiliation_string":"3Nijmegen Center for Molecular Life Sciences, Nijmegen, Netherlands","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045407180","display_name":"Diane S. Lidke","orcid":"https://orcid.org/0000-0001-8533-6029","observed_orcids":["https://orcid.org/0000-0001-8533-6029"]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diane Lidke","raw_affiliation_strings":["University of New Mexico , Albuquerque, NM","1University of New Mexico, Albuquerque, NM"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of New Mexico , Albuquerque, NM","institution_ids":["https://openalex.org/I169521973"]},{"raw_affiliation_string":"1University of New Mexico, Albuquerque, NM","institution_ids":["https://openalex.org/I169521973"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"186","issue":"1_Supplement","first_page":"147.27","last_page":"147.27"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mast-cells","display_name":"mast cells","score":0.8899999856948853},{"id":"https://openalex.org/keywords/dendritic-cells","display_name":"dendritic cells","score":0.9990000128746033},{"id":"https://openalex.org/keywords/antigen-presentation","display_name":"antigen presentation","score":0.7599999904632568},{"id":"https://openalex.org/keywords/multivalent-antigen","display_name":"multivalent antigen","score":0.847000002861023},{"id":"https://openalex.org/keywords/cell-cell-contact","display_name":"cell-cell contact","score":0.6819999814033508},{"id":"https://openalex.org/keywords/soluble-mediators","display_name":"soluble mediators","score":0.8040000200271606},{"id":"https://openalex.org/keywords/anti-inflammatory-cytokines","display_name":"anti-inflammatory cytokines","score":0.9259999990463257},{"id":"https://openalex.org/keywords/dc-maturation","display_name":"DC maturation","score":0.9049999713897705},{"id":"https://openalex.org/keywords/histamine","display_name":"histamine","score":0.5849999785423279},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.6290000081062317},{"id":"https://openalex.org/keywords/prostaglandins","display_name":"prostaglandins","score":0.8709999918937683},{"id":"https://openalex.org/keywords/allergy","display_name":"allergy","score":0.5479999780654907}],"concepts":[{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6544333100318909},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6385318040847778},{"id":"https://openalex.org/C2778170410","wikidata":"https://www.wikidata.org/wiki/Q506253","display_name":"Dendritic cell","level":3,"score":0.6249281167984009},{"id":"https://openalex.org/C2779726688","wikidata":"https://www.wikidata.org/wiki/Q191989","display_name":"Mast cell","level":2,"score":0.6087591648101807},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.5129827857017517},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5089409351348877},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4645962715148926},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4562056064605713},{"id":"https://openalex.org/C1122143","wikidata":"https://www.wikidata.org/wiki/Q61233","display_name":"Histamine","level":2,"score":0.43381890654563904},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.42409518361091614},{"id":"https://openalex.org/C67662055","wikidata":"https://www.wikidata.org/wiki/Q1047791","display_name":"Antigen-presenting cell","level":4,"score":0.41593408584594727},{"id":"https://openalex.org/C189014844","wikidata":"https://www.wikidata.org/wiki/Q189118","display_name":"Cell type","level":3,"score":0.415761262178421},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4150416851043701},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.4119090437889099},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3483718931674957},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.4049/jimmunol.186.supp.147.27","doi":"https://doi.org/10.4049/jimmunol.186.supp.147.27","is_oa":false,"landing_page_url":"https://doi.org/10.4049/jimmunol.186.supp.147.27","pdf_url":null,"source":{"id":"https://openalex.org/S38008053","display_name":"The Journal of Immunology","issn_l":"0022-1767","issn":["0022-1767","1550-6606"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-2","ki-jl-2","medline","norway-2"],"host_organization":"https://openalex.org/P4320800377","host_organization_name":"American Association of Immunologists","host_organization_lineage":["https://openalex.org/P4320800377"],"host_organization_lineage_names":["American Association of Immunologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Immunology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7246000170707703}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.47999998927116394}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2220102944","https://openalex.org/W2409441623","https://openalex.org/W4210976760","https://openalex.org/W2393037700","https://openalex.org/W1664924290","https://openalex.org/W2890187591","https://openalex.org/W2513980881","https://openalex.org/W2027588628","https://openalex.org/W2375999619","https://openalex.org/W2394744011"],"abstract_inverted_index":{"Abstract":[0],"Mast":[1],"cells":[2,58],"(MCs),":[3],"while":[4],"central":[5],"to":[6,20,34,41,55,74,115,175,201],"allergy,":[7],"are":[8,72],"recently":[9],"recognized":[10],"as":[11,96],"functioning":[12],"in":[13,50,53,100,113,152,170,191],"a":[14,67,131,203],"broader":[15],"immune":[16,57,117],"context.":[17],"In":[18],"addition":[19],"mediating":[21],"dendritic":[22],"cell":[23,140],"(DC)":[24],"responses":[25,118],"through":[26,119],"secreted":[27,73],"products,":[28],"MCs":[29,40,85,108,146,174],"also":[30],"present":[31,42],"antigen":[32,43,157],"directly":[33],"T-cells.":[35],"While":[36],"the":[37,92,153,182,192],"ability":[38],"of":[39,65,69,91,133,155,184,194],"under":[44,61],"certain":[45],"conditions":[46],"is":[47,59,105],"clear,":[48],"their":[49],"vivo":[51],"role":[52],"relation":[54],"other":[56],"still":[60],"investigation.":[62],"Upon":[63],"activation":[64],"MCs,":[66],"variety":[68],"soluble":[70,185],"factors":[71],"which":[75],"DCs":[76,87,110,148,176],"respond":[77],"including":[78],"TNF\u03b1,":[79],"prostaglandins,":[80],"and":[81,86,109,122,138,147,163,187],"histamine.":[82],"Additionally,":[83],"both":[84,120],"localize":[88],"within":[89],"many":[90],"same":[93],"tissues,":[94],"and,":[95],"we":[97,129],"demonstrate,":[98],"reside":[99],"close":[101],"proximity.":[102],"Thus,":[103],"it":[104],"possible":[106],"that":[107,145],"could":[111],"work":[112],"conjunction":[114],"mediate":[116],"indirect":[121],"direct":[123,167,198],"mechanisms.":[124],"To":[125],"characterize":[126],"MC-DC":[127],"interactions,":[128],"use":[130],"combination":[132],"ELISAs,":[134],"flow":[135],"cytometry,":[136],"immunohistochemistry,":[137],"live":[139],"confocal":[141],"microscopy.":[142],"We":[143],"show":[144],"form":[149],"prolonged":[150],"interactions":[151,168],"presence":[154],"multivalent":[156],"responsible":[158],"for":[159],"crosslinking":[160],"IgE-primed":[161],"Fc\u03f5RI":[162],"activating":[164],"MCs.":[165],"These":[166],"result":[169],"material":[171],"transfer":[172],"from":[173],"without":[177],"inducing":[178],"DC":[179],"maturation.":[180],"Both":[181],"exchange":[183],"mediators":[186],"cell-cell":[188],"contact":[189,199],"resulted":[190],"production":[193],"anti-inflammatory":[195],"cytokines.":[196],"Interestingly,":[197],"appears":[200],"induce":[202],"stronger":[204],"albeit":[205],"delayed":[206],"response.":[207]},"counts_by_year":[],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}