{"id":"https://openalex.org/W2829129757","doi":"https://doi.org/10.3390/md16070232","title":"Asperindoles A\u2013D and a p-Terphenyl Derivative from the Ascidian-Derived Fungus Aspergillus sp. KMM 4676","display_name":"Asperindoles A\u2013D and a p-Terphenyl Derivative from the Ascidian-Derived Fungus Aspergillus sp. KMM 4676","publication_year":2018,"publication_date":"2018-07-09","ids":{"openalex":"https://openalex.org/W2829129757","doi":"https://doi.org/10.3390/md16070232","mag":"2829129757","pmid":"https://pubmed.ncbi.nlm.nih.gov/29987238","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6070833"},"language":"en","primary_location":{"id":"doi:10.3390/md16070232","doi":"https://doi.org/10.3390/md16070232","is_oa":true,"landing_page_url":"https://doi.org/10.3390/md16070232","pdf_url":"https://www.mdpi.com/1660-3397/16/7/232/pdf?version=1531136097","source":{"id":"https://openalex.org/S146563757","display_name":"Marine Drugs","issn_l":"1660-3397","issn":["1660-3397"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Marine Drugs","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1660-3397/16/7/232/pdf?version=1531136097","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112187406","display_name":"Elena V. Ivanets","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210120806","display_name":"Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/02x9fc857","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210120806","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I4210148470","display_name":"Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/05t43vz03","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210148470"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Elena V. Ivanets","raw_affiliation_strings":["G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia","institution_ids":["https://openalex.org/I4210120806","https://openalex.org/I4210148470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062806775","display_name":"Anton Nikolaevich Yurchenko","orcid":"https://orcid.org/0000-0001-6816-3605","observed_orcids":["https://orcid.org/0000-0001-6816-3605"]},"institutions":[{"id":"https://openalex.org/I4210120806","display_name":"Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/02x9fc857","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210120806","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I4210148470","display_name":"Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/05t43vz03","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210148470"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"Anton N. Yurchenko","raw_affiliation_strings":["G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia"],"raw_orcid":"https://orcid.org/0000-0001-6816-3605","affiliations":[{"raw_affiliation_string":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia","institution_ids":["https://openalex.org/I4210120806","https://openalex.org/I4210148470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113752194","display_name":"O. F. Smetanina","orcid":"https://orcid.org/0009-0003-7246-8876","observed_orcids":["https://orcid.org/0009-0003-7246-8876"]},"institutions":[{"id":"https://openalex.org/I4210120806","display_name":"Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/02x9fc857","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210120806","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I4210148470","display_name":"Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/05t43vz03","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210148470"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Olga F. Smetanina","raw_affiliation_strings":["G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia","institution_ids":["https://openalex.org/I4210120806","https://openalex.org/I4210148470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049871207","display_name":"Anton B. Rasin","orcid":"https://orcid.org/0000-0003-4991-3890","observed_orcids":["https://orcid.org/0000-0003-4991-3890"]},"institutions":[{"id":"https://openalex.org/I4210120806","display_name":"Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/02x9fc857","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210120806","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I4210148470","display_name":"Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/05t43vz03","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210148470"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Anton B. Rasin","raw_affiliation_strings":["G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia","institution_ids":["https://openalex.org/I4210120806","https://openalex.org/I4210148470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010997196","display_name":"Olesya I. Zhuravleva","orcid":"https://orcid.org/0000-0002-9844-240X","observed_orcids":["https://orcid.org/0000-0002-9844-240X"]},"institutions":[{"id":"https://openalex.org/I204947315","display_name":"Far Eastern Federal University","ror":"https://ror.org/0412y9z21","country_code":"RU","type":"education","lineage":["https://openalex.org/I204947315"]},{"id":"https://openalex.org/I4210120806","display_name":"Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/02x9fc857","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210120806","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I4210148470","display_name":"Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/05t43vz03","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210148470"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Olesya I. Zhuravleva","raw_affiliation_strings":["G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia","School of Natural Science, Far Eastern Federal University, Sukhanova St., 8, Vladivostok 690000, Russia","G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia; School of Natural Science, Far Eastern Federal University, Sukhanova St., 8, Vladivostok 690000, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia","institution_ids":["https://openalex.org/I4210120806","https://openalex.org/I4210148470"]},{"raw_affiliation_string":"School of Natural Science, Far Eastern Federal University, Sukhanova St., 8, Vladivostok 690000, Russia","institution_ids":["https://openalex.org/I204947315"]},{"raw_affiliation_string":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia; School of Natural Science, Far Eastern Federal University, Sukhanova St., 8, Vladivostok 690000, Russia","institution_ids":["https://openalex.org/I204947315","https://openalex.org/I4210120806","https://openalex.org/I4210148470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109476779","display_name":"\u041f\u0438\u0432\u043a\u0438\u043d \u041c\u0438\u0445\u0430\u0438\u043b \u0412\u0438\u043a\u0442\u043e\u0440\u043e\u0432\u0438\u0447","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210120806","display_name":"Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/02x9fc857","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210120806","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I4210148470","display_name":"Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/05t43vz03","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210148470"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Mikhail V. Pivkin","raw_affiliation_strings":["G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia","institution_ids":["https://openalex.org/I4210120806","https://openalex.org/I4210148470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047305755","display_name":"Roman Sergeevich Popov","orcid":"https://orcid.org/0000-0002-1727-6164","observed_orcids":["https://orcid.org/0000-0002-1727-6164"]},"institutions":[{"id":"https://openalex.org/I4210120806","display_name":"Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/02x9fc857","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210120806","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I4210148470","display_name":"Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/05t43vz03","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210148470"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Roman S. Popov","raw_affiliation_strings":["G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia","institution_ids":["https://openalex.org/I4210120806","https://openalex.org/I4210148470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038268175","display_name":"Gunhild v. Amsberg","orcid":"https://orcid.org/0000-0002-5176-0507","observed_orcids":["https://orcid.org/0000-0002-5176-0507"]},"institutions":[{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"id":"https://openalex.org/I4210125929","display_name":"University Cancer Center Hamburg","ror":"https://ror.org/02b48z609","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711","https://openalex.org/I4210125929"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Gunhild Von Amsberg","raw_affiliation_strings":["Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711","https://openalex.org/I4210125929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091068907","display_name":"Shamil Sh. Afiyatullov","orcid":"https://orcid.org/0000-0002-5223-2132","observed_orcids":["https://orcid.org/0000-0002-5223-2132"]},"institutions":[{"id":"https://openalex.org/I4210120806","display_name":"Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/02x9fc857","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210120806","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I4210148470","display_name":"Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/05t43vz03","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210148470"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Shamil Sh. Afiyatullov","raw_affiliation_strings":["G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia","institution_ids":["https://openalex.org/I4210120806","https://openalex.org/I4210148470"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079440013","display_name":"Sergey A. Dyshlovoy","orcid":"https://orcid.org/0000-0002-7155-9245","observed_orcids":["https://orcid.org/0000-0002-7155-9245"]},"institutions":[{"id":"https://openalex.org/I204947315","display_name":"Far Eastern Federal University","ror":"https://ror.org/0412y9z21","country_code":"RU","type":"education","lineage":["https://openalex.org/I204947315"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"id":"https://openalex.org/I4210120806","display_name":"Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/02x9fc857","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210120806","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I4210125929","display_name":"University Cancer Center Hamburg","ror":"https://ror.org/02b48z609","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711","https://openalex.org/I4210125929"]},{"id":"https://openalex.org/I4210148470","display_name":"Far Eastern Branch of the Russian Academy of Sciences","ror":"https://ror.org/05t43vz03","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210148470"]}],"countries":["DE","RU"],"is_corresponding":false,"raw_author_name":"Sergey A. Dyshlovoy","raw_affiliation_strings":["G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia","Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany","School of Natural Science, Far Eastern Federal University, Sukhanova St., 8, Vladivostok 690000, Russia","G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia; Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; School of Natural Science, Far Eastern Federal University, Sukhanova St., 8, Vladivostok 690000, Russia"],"raw_orcid":"https://orcid.org/0000-0002-7155-9245","affiliations":[{"raw_affiliation_string":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia","institution_ids":["https://openalex.org/I4210120806","https://openalex.org/I4210148470"]},{"raw_affiliation_string":"Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711","https://openalex.org/I4210125929"]},{"raw_affiliation_string":"School of Natural Science, Far Eastern Federal University, Sukhanova St., 8, Vladivostok 690000, Russia","institution_ids":["https://openalex.org/I204947315"]},{"raw_affiliation_string":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia; Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; School of Natural Science, Far Eastern Federal University, Sukhanova St., 8, Vladivostok 690000, Russia","institution_ids":["https://openalex.org/I204947315","https://openalex.org/I4210108711","https://openalex.org/I4210120806","https://openalex.org/I4210148470"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5062806775"],"corresponding_institution_ids":["https://openalex.org/I4210120806","https://openalex.org/I4210148470"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3499},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3499},"fwci":3.8015,"has_fulltext":true,"cited_by_count":54,"citation_normalized_percentile":{"value":0.95865633,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"16","issue":"7","first_page":"232","last_page":"232"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.9009000062942505,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.9009000062942505,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11340","display_name":"Marine Sponges and Natural Products","score":0.07800000160932541,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13971","display_name":"Isoquinoline Alkaloid Synthesis","score":0.008200000040233135,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/marine-fungi","display_name":"marine fungi","score":0.6890000104904175},{"id":"https://openalex.org/keywords/2-hydroxyisobutyric-acid","display_name":"2-hydroxyisobutyric acid","score":0.9150000214576721},{"id":"https://openalex.org/keywords/absolute-configuration","display_name":"absolute configuration","score":0.9549999833106995},{"id":"https://openalex.org/keywords/structure-elucidation","display_name":"structure elucidation","score":0.796999990940094},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.8669999837875366},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.8489999771118164},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.8529999852180481}],"concepts":[{"id":"https://openalex.org/C2779394022","wikidata":"https://www.wikidata.org/wiki/Q411489","display_name":"Terphenyl","level":2,"score":0.7806116938591003},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.7508460283279419},{"id":"https://openalex.org/C111771559","wikidata":"https://www.wikidata.org/wiki/Q66295","display_name":"Derivative (finance)","level":2,"score":0.5206174850463867},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.47393709421157837},{"id":"https://openalex.org/C2781338088","wikidata":"https://www.wikidata.org/wiki/Q903495","display_name":"Residue (chemistry)","level":2,"score":0.4724422097206116},{"id":"https://openalex.org/C192527728","wikidata":"https://www.wikidata.org/wiki/Q1465700","display_name":"Indole test","level":2,"score":0.4604094922542572},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.4602050185203552},{"id":"https://openalex.org/C2779678110","wikidata":"https://www.wikidata.org/wiki/Q764","display_name":"Fungus","level":2,"score":0.45958155393600464},{"id":"https://openalex.org/C134195300","wikidata":"https://www.wikidata.org/wiki/Q902071","display_name":"Stereocenter","level":4,"score":0.4529581665992737},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.4321359395980835},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3642295002937317},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3047369122505188},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.15823456645011902},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.12363827228546143},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.08611947298049927},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C106159729","wikidata":"https://www.wikidata.org/wiki/Q2294553","display_name":"Financial economics","level":1,"score":0.0},{"id":"https://openalex.org/C146686406","wikidata":"https://www.wikidata.org/wiki/Q898628","display_name":"Enantioselective synthesis","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000077143","descriptor_name":"Docetaxel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001230","descriptor_name":"Aspergillus","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D004224","descriptor_name":"Diterpenes","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D004224","descriptor_name":"Diterpenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004224","descriptor_name":"Diterpenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004354","descriptor_name":"Drug Screening Assays, Antitumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013237","descriptor_name":"Stereoisomerism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014561","descriptor_name":"Urochordata","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D026121","descriptor_name":"Indole Alkaloids","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D026121","descriptor_name":"Indole Alkaloids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D026121","descriptor_name":"Indole Alkaloids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D043823","descriptor_name":"Taxoids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059001","descriptor_name":"Aquatic Organisms","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.3390/md16070232","doi":"https://doi.org/10.3390/md16070232","is_oa":true,"landing_page_url":"https://doi.org/10.3390/md16070232","pdf_url":"https://www.mdpi.com/1660-3397/16/7/232/pdf?version=1531136097","source":{"id":"https://openalex.org/S146563757","display_name":"Marine Drugs","issn_l":"1660-3397","issn":["1660-3397"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Marine Drugs","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5031830","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6070833","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6070833","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6070833","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mar Drugs","raw_type":"Text"},{"id":"pmid:29987238","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29987238","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Marine drugs","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:845db7e8b0a44cf490fc8609f606feb6","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/845db7e8b0a44cf490fc8609f606feb6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Marine Drugs, Vol 16, Iss 7, p 232 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/md16070232","doi":"https://doi.org/10.3390/md16070232","is_oa":true,"landing_page_url":"https://doi.org/10.3390/md16070232","pdf_url":"https://www.mdpi.com/1660-3397/16/7/232/pdf?version=1531136097","source":{"id":"https://openalex.org/S146563757","display_name":"Marine Drugs","issn_l":"1660-3397","issn":["1660-3397"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Marine Drugs","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6000000238418579,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320327851","display_name":"Federal Agency for Scientific Organizations","ror":"https://ror.org/05bvxn785"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2829129757.pdf","grobid_xml":"https://content.openalex.org/works/W2829129757.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W97106607","https://openalex.org/W159851526","https://openalex.org/W1524592071","https://openalex.org/W1626494010","https://openalex.org/W1627971854","https://openalex.org/W1967041926","https://openalex.org/W1973066355","https://openalex.org/W1974954984","https://openalex.org/W1978437029","https://openalex.org/W1988112668","https://openalex.org/W1997216492","https://openalex.org/W2013079392","https://openalex.org/W2015417168","https://openalex.org/W2026684452","https://openalex.org/W2030030050","https://openalex.org/W2031846785","https://openalex.org/W2036421174","https://openalex.org/W2039661716","https://openalex.org/W2043054620","https://openalex.org/W2049336932","https://openalex.org/W2049746223","https://openalex.org/W2067135467","https://openalex.org/W2077529540","https://openalex.org/W2124405908","https://openalex.org/W2136929423","https://openalex.org/W2208134820","https://openalex.org/W2317430721","https://openalex.org/W2323188205","https://openalex.org/W2413465047","https://openalex.org/W2514661881","https://openalex.org/W2738116863","https://openalex.org/W2795628118"],"related_works":["https://openalex.org/W4390176136","https://openalex.org/W2949161822","https://openalex.org/W4417115114","https://openalex.org/W2411294762","https://openalex.org/W1982946733","https://openalex.org/W2952520500","https://openalex.org/W2043613856","https://openalex.org/W7098576006","https://openalex.org/W2986278985","https://openalex.org/W2281740591"],"abstract_inverted_index":{"Four":[0],"new":[1],"indole-diterpene":[2],"alkaloids":[3],"asperindoles":[4],"A\u2013D":[5],"(1\u20134)":[6],"and":[7,40,62,67,89,100],"the":[8,17,21,54],"known":[9],"p-terphenyl":[10],"derivative":[11],"3\u2033-hydroxyterphenyllin":[12],"(5)":[13],"were":[14,35,51],"isolated":[15],"from":[16],"marine-derived":[18],"strain":[19],"of":[20,33,46,49,56],"fungus":[22],"Aspergillus":[23],"sp.,":[24],"associated":[25],"with":[26],"an":[27],"unidentified":[28],"colonial":[29],"ascidian.":[30],"The":[31,43],"structures":[32],"1\u20135":[34],"established":[36],"by":[37,53],"2D":[38],"NMR":[39],"HRESIMS":[41],"data.":[42],"absolute":[44],"configurations":[45],"all":[47],"stereocenters":[48],"1\u20134":[50],"determined":[52],"combination":[55],"ROESY":[57],"data,":[58],"coupling":[59],"constants":[60],"analysis,":[61],"biogenetic":[63],"considerations.":[64],"Asperindoles":[65],"C":[66],"D":[68],"contain":[69],"a":[70],"2-hydroxyisobutyric":[71],"acid":[72],"(2-HIBA)":[73],"residue,":[74],"rarely":[75],"found":[76],"in":[77,103],"natural":[78],"compounds.":[79],"Asperindole":[80],"A":[81],"exhibits":[82],"cytotoxic":[83],"activity":[84],"against":[85],"hormone":[86,94],"therapy-resistant":[87],"PC-3":[88],"22Rv1,":[90],"as":[91,93],"well":[92],"therapy-sensitive":[95],"human":[96],"prostate":[97],"cancer":[98],"cells,":[99],"induces":[101],"apoptosis":[102],"these":[104],"cells":[105],"at":[106],"low-micromolar":[107],"concentrations.":[108]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-07-19T00:00:00"}