{"id":"https://openalex.org/W282133116","doi":null,"title":"[Validity of carbohydrate-deficient transferrine (CDT) in assessing chronic abuse of ethyl alcohol in urban public transport workers].","display_name":"[Validity of carbohydrate-deficient transferrine (CDT) in assessing chronic abuse of ethyl alcohol in urban public transport workers].","publication_year":2009,"publication_date":"2009-09-01","ids":{"openalex":"https://openalex.org/W282133116","mag":"282133116","pmid":"https://pubmed.ncbi.nlm.nih.gov/19960777"},"language":"it","primary_location":{"id":"pmid:19960777","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19960777","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"La Medicina del lavoro","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://air.unimi.it/handle/2434/163279","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015219470","display_name":"Silvia Fustinoni","orcid":"https://orcid.org/0000-0002-0287-7338","observed_orcids":["https://orcid.org/0000-0002-0287-7338"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I2803066834","display_name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico","ror":"https://ror.org/016zn0y21","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I189158943","https://openalex.org/I2803066834","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Silvia Fustinoni","raw_affiliation_strings":["Unit\u00e1 Operativa di Epidemiologia, Dipartimento di Medicina Preventiva, del Lavoro e dell'Ambiente \"Clinica del Lavoro L. Devoto\", Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena e Universit\u00e0 degli Studi di Milano, Milano, Italy. silvia.fustinoni@unimi.it"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit\u00e1 Operativa di Epidemiologia, Dipartimento di Medicina Preventiva, del Lavoro e dell'Ambiente \"Clinica del Lavoro L. Devoto\", Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena e Universit\u00e0 degli Studi di Milano, Milano, Italy. silvia.fustinoni@unimi.it","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I2803066834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029634755","display_name":"Maurizio Vecchi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M De Vecchi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078798886","display_name":"Lorenzo Bordini","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Bordini","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"A Todaro","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Todaro","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012657878","display_name":"Luciano Riboldi","orcid":"https://orcid.org/0000-0002-7482-1210","observed_orcids":["https://orcid.org/0000-0002-7482-1210"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Riboldi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5002376961","display_name":"Pier Alberto Bertazzi","orcid":"https://orcid.org/0000-0003-3475-2449","observed_orcids":["https://orcid.org/0000-0003-3475-2449"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P A Bertazzi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6172,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.71162791,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"100","issue":"5","first_page":"359","last_page":"69"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carbohydrate-deficient-transferrin","display_name":"carbohydrate-deficient transferrin","score":1.0},{"id":"https://openalex.org/keywords/chronic-alcohol-abuse","display_name":"chronic alcohol abuse","score":0.8859999775886536},{"id":"https://openalex.org/keywords/ethanol-intake","display_name":"ethanol consumption","score":0.5080000162124634},{"id":"https://openalex.org/keywords/tram-drivers","display_name":"tram drivers","score":0.8059999942779541},{"id":"https://openalex.org/keywords/occupational-health-surveillance","display_name":"occupational health surveillance","score":0.7390000224113464},{"id":"https://openalex.org/keywords/gamma-glutamyl-transferase","display_name":"gamma-glutamyl transferase","score":0.968999981880188},{"id":"https://openalex.org/keywords/mean-corpuscular-volume","display_name":"mean corpuscular volume","score":0.9909999966621399},{"id":"https://openalex.org/keywords/liver-enzymes","display_name":"liver enzymes","score":0.5849999785423279},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.7850000262260437},{"id":"https://openalex.org/keywords/workplace-alcohol-screening","display_name":"workplace alcohol screening","score":0.5270000100135803}],"concepts":[{"id":"https://openalex.org/C2781058662","wikidata":"https://www.wikidata.org/wiki/Q1358504","display_name":"Mean corpuscular volume","level":3,"score":0.6902235746383667},{"id":"https://openalex.org/C2780931562","wikidata":"https://www.wikidata.org/wiki/Q7331102","display_name":"Alcohol abuse","level":2,"score":0.6195452213287354},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5903507471084595},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5871238112449646},{"id":"https://openalex.org/C2778248655","wikidata":"https://www.wikidata.org/wiki/Q408992","display_name":"Carbohydrate deficient transferrin","level":4,"score":0.5411173701286316},{"id":"https://openalex.org/C2781278919","wikidata":"https://www.wikidata.org/wiki/Q285870","display_name":"Gamma-glutamyltransferase","level":3,"score":0.528112530708313},{"id":"https://openalex.org/C2781066024","wikidata":"https://www.wikidata.org/wiki/Q156","display_name":"Alcohol","level":2,"score":0.49916648864746094},{"id":"https://openalex.org/C3019719930","wikidata":"https://www.wikidata.org/wiki/Q3910099","display_name":"Predictive value","level":2,"score":0.4352220892906189},{"id":"https://openalex.org/C2780161600","wikidata":"https://www.wikidata.org/wiki/Q153","display_name":"Ethanol","level":2,"score":0.43076905608177185},{"id":"https://openalex.org/C2992872382","wikidata":"https://www.wikidata.org/wiki/Q305481","display_name":"Alanine aminotransferase","level":2,"score":0.4211446940898895},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.41725316643714905},{"id":"https://openalex.org/C3019635848","wikidata":"https://www.wikidata.org/wiki/Q154","display_name":"Alcohol consumption","level":3,"score":0.2378462255001068},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.20532873272895813},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.2009662687778473},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.14327725768089294},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10410383343696594},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.09037888050079346}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000437","descriptor_name":"Alcoholism","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D002947","descriptor_name":"Cities","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009784","descriptor_name":"Occupational Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009790","descriptor_name":"Occupations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D014168","descriptor_name":"Transferrin","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D014168","descriptor_name":"Transferrin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014186","descriptor_name":"Transportation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmid:19960777","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19960777","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"La Medicina del lavoro","raw_type":"Comparative Study"},{"id":"mag:2189026272","doi":null,"is_oa":true,"landing_page_url":"https://air.unimi.it/handle/2434/163279","pdf_url":null,"source":{"id":"https://openalex.org/S105770365","display_name":"La Medicina del Lavoro","issn_l":"0025-7818","issn":["0025-7818","2532-1080"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4322765259","host_organization_name":"Italian Society of Occupational Medicine","host_organization_lineage":["https://openalex.org/P4322765259"],"host_organization_lineage_names":["Italian Society of Occupational Medicine"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u0098La \u009cMedicina del lavoro","raw_type":null},{"id":"mag:282133116","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19960777","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"mag:2189026272","doi":null,"is_oa":true,"landing_page_url":"https://air.unimi.it/handle/2434/163279","pdf_url":null,"source":{"id":"https://openalex.org/S105770365","display_name":"La Medicina del Lavoro","issn_l":"0025-7818","issn":["0025-7818","2532-1080"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4322765259","host_organization_name":"Italian Society of Occupational Medicine","host_organization_lineage":["https://openalex.org/P4322765259"],"host_organization_lineage_names":["Italian Society of Occupational Medicine"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u0098La \u009cMedicina del lavoro","raw_type":null},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W101980984","https://openalex.org/W174994520","https://openalex.org/W1636736913","https://openalex.org/W1862058525","https://openalex.org/W1965233368","https://openalex.org/W1987988504","https://openalex.org/W1996001506","https://openalex.org/W2018900157","https://openalex.org/W2024494902","https://openalex.org/W2028736792","https://openalex.org/W2033923891","https://openalex.org/W2049739308","https://openalex.org/W2085059034","https://openalex.org/W2095018794","https://openalex.org/W2110628597","https://openalex.org/W2114013309","https://openalex.org/W2123613968","https://openalex.org/W2129584475","https://openalex.org/W2132741956"],"related_works":["https://openalex.org/W2189026272","https://openalex.org/W1980249810","https://openalex.org/W2160881977","https://openalex.org/W2022097214","https://openalex.org/W2267925587","https://openalex.org/W2240709238","https://openalex.org/W2403032105","https://openalex.org/W2602211196","https://openalex.org/W2130501479","https://openalex.org/W1999715951"],"abstract_inverted_index":{"OBJECTIVES:":[0],"The":[1,98,122,149,205,275],"aim":[2],"of":[3,11,26,31,55,88,109,125,146,151,158,207,253,256,265,273,277,298],"this":[4,266],"study":[5,74],"was":[6,58,161,177,196,203],"to":[7,68,106,143,214,289],"verify":[8],"the":[9,38,49,53,61,73,76,144,166,174,180,183,192,199,218,242,246,251,263],"ability":[10],"some":[12],"chemical-clinical":[13],"parameters,":[14],"with":[15,137,182,209,304],"particular":[16],"emphasis":[17],"on":[18,52,168,292],"carbohydrate-deficient":[19],"transferrin":[20],"(CDT),":[21],"in":[22,28,132,135,141,154,217,241,296],"assessing":[23],"chronic":[24,156,254],"abuse":[25,157,255],"ethanol":[27,147],"a":[29,286,301,305],"group":[30],"urban":[32],"public":[33,41],"transport":[34,42],"workers.":[35],"METHODS:":[36],"In":[37,72],"512":[39],"subjects,":[40],"tram":[43],"drivers,":[44],"all":[45],"males,":[46],"who":[47],"entered":[48],"study,":[50],"information":[51,291],"intake":[54,170],"alcoholic":[56],"beverages":[57],"collected":[59],"during":[60],"periodical":[62],"health":[63],"surveillance":[64],"controls":[65],"performed":[66],"according":[67,105],"Italian":[69],"legislation":[70],"(DM88/99).":[71],"subjects":[75,99],"following":[77],"clinical-chemical":[78],"parameters":[79],"were":[80,100,130],"measured:":[81],"CDT":[82,126,176,208,226,232,244,300],"gamma-glutamyltransferase":[83],"(GGT),":[84],"mean":[85],"corpuscular":[86],"volume":[87],"erythrocytes":[89],"(MCV),":[90],"aspartate":[91],"aminotransferase":[92,95],"(AST),":[93],"alanine":[94],"(ALT).":[96],"RESULTS:":[97],"divided":[101],"into":[102],"five":[103],"groups":[104],"different":[107],"levels":[108],"alcohol":[110,160,169,257,293],"intake:":[111],"non-drinkers,":[112,136],"occasional":[113],"drinkers,":[114,116],"moderate":[115],"habitual":[117],"drinkers":[118,133],"and":[119,128,186,189,227,229,233,295],"heavy":[120],"drinkers.":[121],"median":[123],"values":[124],"GGT":[127,210],"MCV":[129,212,228],"higher":[131],"than":[134],"an":[138],"increasing":[139],"trend":[140],"proportion":[142],"amount":[145],"ingested.":[148],"validity":[150],"each":[152],"parameter":[153,181,249],"determining":[155],"ethyl":[159],"calculated":[162],"taking":[163],"as":[164,179,271,285],"true":[165],"statement":[167],"made":[171],"spontaneously":[172],"by":[173],"subject.":[175],"confirmed":[178,238],"best":[184],"sensitivity":[185],"specificity:":[187],"90%":[188],"98%,":[190],"respectively,":[191],"negative":[193],"predictive":[194,201,220],"value":[195],"99%,":[197],"while":[198],"positive":[200,219,299],"power":[202],"45%.":[204],"combination":[206],"or":[211],"led":[213],"small":[215],"improvements":[216],"ability,":[221],"which":[222],"reached":[223],"50%":[224],"for":[225,231,250],"60%":[230],"GGT.":[234],"CONCLUSIONS:":[235],"Our":[236],"results":[237],"that,":[239],"also":[240,260],"workplace,":[243],"is":[245,281],"most":[247],"important":[248],"diagnosis":[252],"intake,":[258,294],"but":[259],"showed":[261],"that":[262],"positivity":[264],"marker":[267],"cannot":[268],"be":[269],"taken":[270],"certainty":[272],"abuse.":[274],"adoption":[276],"further":[278],"diagnostic":[279],"tools":[280],"therefore":[282],"proposed,":[283],"such":[284],"specific":[287],"questionnaire":[288],"collect":[290],"case":[297],"second-level":[302],"test":[303],"high":[306],"specificity.":[307]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}