{"id":"https://openalex.org/W2811274306","doi":"https://doi.org/10.2217/epi-2017-0147","title":"Time- and Sex-Dependent Associations Between Prenatal Alcohol Exposure and Placental Global DNA Methylation","display_name":"Time- and Sex-Dependent Associations Between Prenatal Alcohol Exposure and Placental Global DNA Methylation","publication_year":2018,"publication_date":"2018-06-29","ids":{"openalex":"https://openalex.org/W2811274306","doi":"https://doi.org/10.2217/epi-2017-0147","mag":"2811274306","pmid":"https://pubmed.ncbi.nlm.nih.gov/29956547"},"language":"en","primary_location":{"id":"doi:10.2217/epi-2017-0147","doi":"https://doi.org/10.2217/epi-2017-0147","is_oa":false,"landing_page_url":"https://doi.org/10.2217/epi-2017-0147","pdf_url":null,"source":{"id":"https://openalex.org/S42283280","display_name":"Epigenomics","issn_l":"1750-1911","issn":["1750-1911","1750-192X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epigenomics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/journal_contribution/Time-_and_sex-dependent_associations_between_prenatal_alcohol_exposure_and_placental_global_DNA_methylation/20799703","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052564316","display_name":"Yuk Jing Loke","orcid":"https://orcid.org/0000-0001-7966-8916","observed_orcids":["https://orcid.org/0000-0001-7966-8916"]},"institutions":[{"id":"https://openalex.org/I1321649718","display_name":"Royal Children's Hospital","ror":"https://ror.org/02rktxt32","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1321649718"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Yuk Jing Loke","raw_affiliation_strings":["Environmental & Genetic Epidemiology Research, Murdoch Children\u2019s Research Institute, the Royal Children\u2019s Hospital, Flemington Road, Parkville, Victoria 3052, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Environmental & Genetic Epidemiology Research, Murdoch Children\u2019s Research Institute, the Royal Children\u2019s Hospital, Flemington Road, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I1321649718","https://openalex.org/I4210150290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089961621","display_name":"Evelyne Muggli","orcid":"https://orcid.org/0000-0002-8102-9811","observed_orcids":["https://orcid.org/0000-0002-8102-9811"]},"institutions":[{"id":"https://openalex.org/I1321649718","display_name":"Royal Children's Hospital","ror":"https://ror.org/02rktxt32","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1321649718"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Evelyne Muggli","raw_affiliation_strings":["Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia","Public Health Genetics, Murdoch Children\u2019s Research Institute, the Royal Children\u2019s Hospital, Flemington Road, Parkville, Victoria 3052, Australia","Public Health Genetics, Murdoch Children's Research Institute, the Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Public Health Genetics, Murdoch Children\u2019s Research Institute, the Royal Children\u2019s Hospital, Flemington Road, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I1321649718","https://openalex.org/I4210150290"]},{"raw_affiliation_string":"Public Health Genetics, Murdoch Children's Research Institute, the Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I1321649718","https://openalex.org/I165779595","https://openalex.org/I4210150290"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Linh Nguyen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1321649718","display_name":"Royal Children's Hospital","ror":"https://ror.org/02rktxt32","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1321649718"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Linh Nguyen","raw_affiliation_strings":["Environmental & Genetic Epidemiology Research, Murdoch Children\u2019s Research Institute, the Royal Children\u2019s Hospital, Flemington Road, Parkville, Victoria 3052, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Environmental & Genetic Epidemiology Research, Murdoch Children\u2019s Research Institute, the Royal Children\u2019s Hospital, Flemington Road, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I1321649718","https://openalex.org/I4210150290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081383005","display_name":"Joanne L. Ryan","orcid":"https://orcid.org/0000-0002-7039-6325","observed_orcids":["https://orcid.org/0000-0002-7039-6325"]},"institutions":[{"id":"https://openalex.org/I1321649718","display_name":"Royal Children's Hospital","ror":"https://ror.org/02rktxt32","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1321649718"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]},{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Joanne Ryan","raw_affiliation_strings":["Cancer & Disease Epigenetics, Murdoch Children\u2019s Research Institute, the Royal Children\u2019s Hospital, Flemington Road, Parkville, Victoria 3052, Australia","Department of Epidemiology & Preventive Medicine, Monash University, Melbourne, Victoria 3004, Australia","Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia","Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia Department of Epidemiology & Preventive Medicine, Monash University, Melbourne, Victoria 3004, Australia Cancer & Disease Epigenetics, Murdoch Children's Research Institute, the Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer & Disease Epigenetics, Murdoch Children\u2019s Research Institute, the Royal Children\u2019s Hospital, Flemington Road, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I1321649718","https://openalex.org/I4210150290"]},{"raw_affiliation_string":"Department of Epidemiology & Preventive Medicine, Monash University, Melbourne, Victoria 3004, Australia","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia Department of Epidemiology & Preventive Medicine, Monash University, Melbourne, Victoria 3004, Australia Cancer & Disease Epigenetics, Murdoch Children's Research Institute, the Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I1321649718","https://openalex.org/I165779595","https://openalex.org/I4210150290","https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082673477","display_name":"Richard Saffery","orcid":"https://orcid.org/0000-0002-9510-4181","observed_orcids":["https://orcid.org/0000-0002-9510-4181","https://orcid.org/0000-0002-5623-9008"]},"institutions":[{"id":"https://openalex.org/I1321649718","display_name":"Royal Children's Hospital","ror":"https://ror.org/02rktxt32","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1321649718"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Richard Saffery","raw_affiliation_strings":["Cancer & Disease Epigenetics, Murdoch Children\u2019s Research Institute, the Royal Children\u2019s Hospital, Flemington Road, Parkville, Victoria 3052, Australia","Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia","Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia Cancer & Disease Epigenetics, Murdoch Children's Research Institute, the Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer & Disease Epigenetics, Murdoch Children\u2019s Research Institute, the Royal Children\u2019s Hospital, Flemington Road, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I1321649718","https://openalex.org/I4210150290"]},{"raw_affiliation_string":"Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia Cancer & Disease Epigenetics, Murdoch Children's Research Institute, the Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I1321649718","https://openalex.org/I165779595","https://openalex.org/I4210150290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056510036","display_name":"Elizabeth Jane Elliott","orcid":"https://orcid.org/0000-0002-6501-5487","observed_orcids":["https://orcid.org/0000-0002-6501-5487"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I2802384191","display_name":"Children's Hospital at Westmead","ror":"https://ror.org/05k0s5494","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2802384191"]},{"id":"https://openalex.org/I4210149013","display_name":"Sydney Children\u2019s Hospitals Network","ror":"https://ror.org/04d87y574","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210149013"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Elizabeth J Elliott","raw_affiliation_strings":["Australian Paediatric Surveillance Unit, Sydney Childrens Hospitals Network, Westmead, Sydney, New South Wales, Australia","Discipline of Child & Adolescent Health, School of Medicine and Health, University of Sydney, Sydney 2006, New South Wales, Australia","Discipline of Child & Adolescent Health, School of Medicine and Health, University of Sydney, Sydney 2006, New South Wales, Australia Australian Paediatric Surveillance Unit, Sydney Childrens Hospitals Network, Westmead, Sydney, New South Wales, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Australian Paediatric Surveillance Unit, Sydney Childrens Hospitals Network, Westmead, Sydney, New South Wales, Australia","institution_ids":["https://openalex.org/I2802384191","https://openalex.org/I4210149013"]},{"raw_affiliation_string":"Discipline of Child & Adolescent Health, School of Medicine and Health, University of Sydney, Sydney 2006, New South Wales, Australia","institution_ids":["https://openalex.org/I129604602"]},{"raw_affiliation_string":"Discipline of Child & Adolescent Health, School of Medicine and Health, University of Sydney, Sydney 2006, New South Wales, Australia Australian Paediatric Surveillance Unit, Sydney Childrens Hospitals Network, Westmead, Sydney, New South Wales, Australia","institution_ids":["https://openalex.org/I129604602","https://openalex.org/I4210149013"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086543668","display_name":"Jane L. Halliday","orcid":"https://orcid.org/0000-0001-6206-3857","observed_orcids":["https://orcid.org/0000-0001-6206-3857"]},"institutions":[{"id":"https://openalex.org/I1321649718","display_name":"Royal Children's Hospital","ror":"https://ror.org/02rktxt32","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1321649718"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jane Halliday","raw_affiliation_strings":["Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia","Public Health Genetics, Murdoch Children\u2019s Research Institute, the Royal Children\u2019s Hospital, Flemington Road, Parkville, Victoria 3052, Australia","Public Health Genetics, Murdoch Children's Research Institute, the Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Public Health Genetics, Murdoch Children\u2019s Research Institute, the Royal Children\u2019s Hospital, Flemington Road, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I1321649718","https://openalex.org/I4210150290"]},{"raw_affiliation_string":"Public Health Genetics, Murdoch Children's Research Institute, the Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I1321649718","https://openalex.org/I165779595","https://openalex.org/I4210150290"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082453156","display_name":"Jeffrey Mark Craig","orcid":"https://orcid.org/0000-0003-3979-7849","observed_orcids":["https://orcid.org/0000-0003-3979-7849","https://orcid.org/0000-0003-1295-3258"]},"institutions":[{"id":"https://openalex.org/I1321649718","display_name":"Royal Children's Hospital","ror":"https://ror.org/02rktxt32","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1321649718"]},{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jeffrey M Craig","raw_affiliation_strings":["Centre for Molecular and Medical Research, Deakin University, Geelong Waurn Ponds Campus, Locked Bag 20000, Geelong, Victoria 3220, Australia","Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia","Environmental & Genetic Epidemiology Research, Murdoch Children\u2019s Research Institute, the Royal Children\u2019s Hospital, Flemington Road, Parkville, Victoria 3052, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Molecular and Medical Research, Deakin University, Geelong Waurn Ponds Campus, Locked Bag 20000, Geelong, Victoria 3220, Australia","institution_ids":["https://openalex.org/I149704539"]},{"raw_affiliation_string":"Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Environmental & Genetic Epidemiology Research, Murdoch Children\u2019s Research Institute, the Royal Children\u2019s Hospital, Flemington Road, Parkville, Victoria 3052, Australia","institution_ids":["https://openalex.org/I1321649718","https://openalex.org/I4210150290"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.6592,"has_fulltext":false,"cited_by_count":47,"citation_normalized_percentile":{"value":0.84385166,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"10","issue":"7","first_page":"981","last_page":"991"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.48730000853538513,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.48730000853538513,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.47360000014305115,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.03400000184774399,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prenatal-alcohol-exposure","display_name":"prenatal alcohol exposure","score":1.0},{"id":"https://openalex.org/keywords/placental-dna-methylation","display_name":"placental DNA methylation","score":0.8379999995231628},{"id":"https://openalex.org/keywords/global-dna-methylation","display_name":"global DNA methylation","score":0.9549999833106995},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6930000185966492},{"id":"https://openalex.org/keywords/fetal-alcohol-spectrum-disorders","display_name":"fetal alcohol spectrum disorders","score":0.7310000061988831},{"id":"https://openalex.org/keywords/epigenetics","display_name":"epigenetics","score":0.7480000257492065},{"id":"https://openalex.org/keywords/alu-elements","display_name":"Alu elements","score":0.7129999995231628},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.36800000071525574}],"concepts":[{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.883971095085144},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8071571588516235},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.6948248147964478},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.6881570219993591},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.5601419806480408},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.5238059759140015},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.44243818521499634},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.3836178779602051},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3412788510322571},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.32129114866256714},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.31072503328323364},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.19057244062423706},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11219191551208496},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.08994844555854797}],"mesh":[{"descriptor_ui":"D000428","descriptor_name":"Alcohol Drinking","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010920","descriptor_name":"Placenta","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011297","descriptor_name":"Prenatal Exposure Delayed Effects","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018811","descriptor_name":"Maternal Exposure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.2217/epi-2017-0147","doi":"https://doi.org/10.2217/epi-2017-0147","is_oa":false,"landing_page_url":"https://doi.org/10.2217/epi-2017-0147","pdf_url":null,"source":{"id":"https://openalex.org/S42283280","display_name":"Epigenomics","issn_l":"1750-1911","issn":["1750-1911","1750-192X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epigenomics","raw_type":"journal-article"},{"id":"pmid:29956547","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29956547","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epigenomics","raw_type":"Journal Article"},{"id":"pmh:oai:figshare.com:article/20799703","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Time-_and_sex-dependent_associations_between_prenatal_alcohol_exposure_and_placental_global_DNA_methylation/20799703","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"mag:3014448223","doi":null,"is_oa":false,"landing_page_url":"https://findanexpert.unimelb.edu.au/scholarlywork/1341867-time--and-sex-dependent-associations-between-prenatal-alcohol-exposure","pdf_url":null,"source":{"id":"https://openalex.org/S42283280","display_name":"Epigenomics","issn_l":"1750-1911","issn":["1750-1911","1750-192X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Epigenomics","raw_type":null}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/20799703","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Time-_and_sex-dependent_associations_between_prenatal_alcohol_exposure_and_placental_global_DNA_methylation/20799703","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322858","display_name":"State Government of Victoria","ror":"https://ror.org/02xvc5r05"},{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","ror":"https://ror.org/011kf5r70"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W79056978","https://openalex.org/W576587577","https://openalex.org/W1508295517","https://openalex.org/W1558222595","https://openalex.org/W1597686096","https://openalex.org/W1787312299","https://openalex.org/W1857735207","https://openalex.org/W1963990067","https://openalex.org/W1967260099","https://openalex.org/W1967677629","https://openalex.org/W1979824342","https://openalex.org/W1986684176","https://openalex.org/W1989989220","https://openalex.org/W1999194325","https://openalex.org/W2013844122","https://openalex.org/W2029269100","https://openalex.org/W2043057028","https://openalex.org/W2049422251","https://openalex.org/W2063094219","https://openalex.org/W2080572891","https://openalex.org/W2098362718","https://openalex.org/W2099281541","https://openalex.org/W2107493561","https://openalex.org/W2114102588","https://openalex.org/W2120501286","https://openalex.org/W2135670457","https://openalex.org/W2138541585","https://openalex.org/W2139075355","https://openalex.org/W2150272037","https://openalex.org/W2150310487","https://openalex.org/W2152389958","https://openalex.org/W2166851046","https://openalex.org/W2170852825","https://openalex.org/W2400490172","https://openalex.org/W2412495588","https://openalex.org/W2421217190","https://openalex.org/W2473552052","https://openalex.org/W2504586376","https://openalex.org/W2556381214","https://openalex.org/W2557261829","https://openalex.org/W2564291134","https://openalex.org/W2572270804","https://openalex.org/W2575074732","https://openalex.org/W2581053432","https://openalex.org/W2587150222","https://openalex.org/W2587245487","https://openalex.org/W2588013675","https://openalex.org/W2588065226","https://openalex.org/W2605358691","https://openalex.org/W2622695354","https://openalex.org/W2755854229","https://openalex.org/W4234055745"],"related_works":["https://openalex.org/W3014448223","https://openalex.org/W4407349150","https://openalex.org/W3215972889","https://openalex.org/W7222562509","https://openalex.org/W7042408174","https://openalex.org/W7219557758","https://openalex.org/W6902542045","https://openalex.org/W2739729724","https://openalex.org/W4402667819","https://openalex.org/W4389453603"],"abstract_inverted_index":{"AIM:":[0],"Epigenetic":[1],"changes,":[2],"in":[3,5],"particular":[4],"the":[6,10,22,44,59],"placenta,":[7],"may":[8,112],"mediate":[9],"effects":[11,115],"of":[12,62,75,107],"prenatal":[13],"alcohol":[14,122],"exposure":[15],"(PAE)":[16],"on":[17,28,116],"children's":[18],"health.":[19],"We":[20],"examined":[21,43],"relationship":[23],"between":[24,46,78],"PAE":[25,48,79,92,111],"patterns,":[26],"based":[27],"dose":[29],"and":[30,32,50,80],"timing,":[31],"placental":[33,51,81,99,117],"global":[34,52,82,100,118],"DNA":[35,53,83,101,119],"methylation.":[36],"METHODS:":[37],"Using":[38],"linear":[39],"regression":[40],"analysis,":[41],"we":[42,71],"association":[45,77],"different":[47],"categories":[49],"methylation":[54,84,102,120],"(n":[55],"=":[56,105],"187),":[57],"using":[58],"proxy":[60],"measure":[61],"Alu-interspersed":[63],"repeats.":[64],"RESULTS:":[65],"Following":[66],"adjustment":[67],"for":[68],"important":[69],"covariates,":[70],"found":[72],"no":[73],"evidence":[74],"an":[76],"overall.":[85],"However,":[86],"when":[87],"stratifying":[88],"by":[89],"newborn":[90],"sex,":[91],"throughout":[93,125],"pregnancy":[94],"was":[95],"associated":[96],"with":[97],"higher":[98],"(1.5%;":[103],"p":[104],"0.01)":[106],"male":[108],"newborns.":[109],"CONCLUSION:":[110],"have":[113],"sex-specific":[114],"if":[121],"is":[123],"consumed":[124],"pregnancy.":[126]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":15},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2018-07-10T00:00:00"}