{"id":"https://openalex.org/W2811223977","doi":"https://doi.org/10.1016/j.carbpol.2018.06.119","title":"Facile and green synthesis of pullulan derivative-stabilized Au nanoparticles as drug carriers for enhancing anticancer activity","display_name":"Facile and green synthesis of pullulan derivative-stabilized Au nanoparticles as drug carriers for enhancing anticancer activity","publication_year":2018,"publication_date":"2018-06-30","ids":{"openalex":"https://openalex.org/W2811223977","doi":"https://doi.org/10.1016/j.carbpol.2018.06.119","mag":"2811223977","pmid":"https://pubmed.ncbi.nlm.nih.gov/30093027"},"language":"en","primary_location":{"id":"doi:10.1016/j.carbpol.2018.06.119","doi":"https://doi.org/10.1016/j.carbpol.2018.06.119","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.carbpol.2018.06.119","pdf_url":null,"source":{"id":"https://openalex.org/S64311837","display_name":"Carbohydrate Polymers","issn_l":"0144-8617","issn":["0144-8617","1879-1344"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Carbohydrate Polymers","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033737023","display_name":"Sakchai Laksee","orcid":"https://orcid.org/0000-0002-2533-8820","observed_orcids":["https://orcid.org/0000-0002-2533-8820"]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Sakchai Laksee","raw_affiliation_strings":["Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017294339","display_name":"Songchan Puthong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Songchan Puthong","raw_affiliation_strings":["Antibody Production Research Unit, Institute of Biotechnology and Genetic Engineering, Chulalongkorn University, Bangkok 10330, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Antibody Production Research Unit, Institute of Biotechnology and Genetic Engineering, Chulalongkorn University, Bangkok 10330, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069963477","display_name":"Pornrat Kongkavitoon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Pornrat Kongkavitoon","raw_affiliation_strings":["Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060914553","display_name":"Tanapat Palaga","orcid":"https://orcid.org/0000-0001-8734-6626","observed_orcids":["https://orcid.org/0000-0001-8734-6626"]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Tanapat Palaga","raw_affiliation_strings":["Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036271066","display_name":"Nongnuj Muangsin","orcid":"https://orcid.org/0000-0001-7961-3114","observed_orcids":["https://orcid.org/0000-0001-7961-3114","https://orcid.org/0000-0001-6799-8838"]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":true,"raw_author_name":"Nongnuj Muangsin","raw_affiliation_strings":["Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: nongnuj.j@chula.ac.th","Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand"],"raw_orcid":"https://orcid.org/0000-0001-7961-3114","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: nongnuj.j@chula.ac.th","institution_ids":["https://openalex.org/I158708052"]},{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand","institution_ids":["https://openalex.org/I158708052"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5036271066"],"corresponding_institution_ids":["https://openalex.org/I158708052"],"apc_list":{"value":5340,"currency":"USD","value_usd":5340},"apc_paid":null,"fwci":2.147,"has_fulltext":false,"cited_by_count":62,"citation_normalized_percentile":{"value":0.87233466,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"198","issue":null,"first_page":"495","last_page":"508"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10131","display_name":"Gold and Silver Nanoparticles Synthesis and Applications","score":0.02319999970495701,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11686","display_name":"Dendrimers and Hyperbranched Polymers","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gold-nanoparticles","display_name":"gold nanoparticles","score":0.9589999914169312},{"id":"https://openalex.org/keywords/pullulan-derivatives","display_name":"pullulan derivatives","score":0.7670000195503235},{"id":"https://openalex.org/keywords/p-aminobenzoic-acid","display_name":"p-aminobenzoic acid","score":0.7889999747276306},{"id":"https://openalex.org/keywords/quaternary-ammonium-salts","display_name":"quaternary ammonium compounds","score":0.7490000128746033},{"id":"https://openalex.org/keywords/green-synthesis","display_name":"green synthesis","score":0.8489999771118164},{"id":"https://openalex.org/keywords/doxorubicin","display_name":"doxorubicin","score":0.8090000152587891},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"drug delivery","score":0.7400000095367432},{"id":"https://openalex.org/keywords/anticancer-nanocarriers","display_name":"anticancer nanocarriers","score":0.7350000143051147},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.8009999990463257},{"id":"https://openalex.org/keywords/cell-cycle-arrest","display_name":"cell cycle arrest","score":0.8169999718666077},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.949999988079071},{"id":"https://openalex.org/keywords/endocytosis","display_name":"endocytosis","score":0.8130000233650208},{"id":"https://openalex.org/keywords/intracellular-drug-uptake","display_name":"intracellular drug uptake","score":0.6240000128746033},{"id":"https://openalex.org/keywords/drug-loading","display_name":"drug loading","score":0.7870000004768372}],"concepts":[{"id":"https://openalex.org/C2779257994","wikidata":"https://www.wikidata.org/wiki/Q419779","display_name":"Pullulan","level":3,"score":0.9011696577072144},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.8803043365478516},{"id":"https://openalex.org/C18150654","wikidata":"https://www.wikidata.org/wiki/Q17153796","display_name":"Nanocarriers","level":3,"score":0.7795915603637695},{"id":"https://openalex.org/C86181022","wikidata":"https://www.wikidata.org/wiki/Q196823","display_name":"Zeta potential","level":3,"score":0.75534987449646},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5547319650650024},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.5248765349388123},{"id":"https://openalex.org/C2781303535","wikidata":"https://www.wikidata.org/wiki/Q18936","display_name":"Doxorubicin","level":3,"score":0.5222147703170776},{"id":"https://openalex.org/C28005876","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytosis","level":3,"score":0.5069194436073303},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.46280142664909363},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.44281625747680664},{"id":"https://openalex.org/C2777752497","wikidata":"https://www.wikidata.org/wiki/Q286779","display_name":"IC50","level":3,"score":0.4402419924736023},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.37720075249671936},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.35513317584991455},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.3314835727214813},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3208223581314087},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.2851262092590332},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2654576003551483},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2602890133857727},{"id":"https://openalex.org/C100817775","wikidata":"https://www.wikidata.org/wiki/Q134219","display_name":"Polysaccharide","level":2,"score":0.24184176325798035},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.17923420667648315},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.1285901963710785},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.07743042707443237},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06560888886451721},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000644","descriptor_name":"Quaternary Ammonium Compounds","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000644","descriptor_name":"Quaternary Ammonium Compounds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D002453","descriptor_name":"Cell Cycle","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004317","descriptor_name":"Doxorubicin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D004317","descriptor_name":"Doxorubicin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004337","descriptor_name":"Drug Carriers","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D004337","descriptor_name":"Drug Carriers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D004705","descriptor_name":"Endocytosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005936","descriptor_name":"Glucans","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D005936","descriptor_name":"Glucans","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010129","descriptor_name":"4-Aminobenzoic Acid","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010129","descriptor_name":"4-Aminobenzoic Acid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D055772","descriptor_name":"Green Chemistry Technology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.carbpol.2018.06.119","doi":"https://doi.org/10.1016/j.carbpol.2018.06.119","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.carbpol.2018.06.119","pdf_url":null,"source":{"id":"https://openalex.org/S64311837","display_name":"Carbohydrate Polymers","issn_l":"0144-8617","issn":["0144-8617","1879-1344"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Carbohydrate Polymers","raw_type":"journal-article"},{"id":"pmid:30093027","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30093027","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Carbohydrate polymers","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321557","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1901572159","https://openalex.org/W1966360238","https://openalex.org/W1972011250","https://openalex.org/W1980738179","https://openalex.org/W1980864016","https://openalex.org/W1981317034","https://openalex.org/W1984076071","https://openalex.org/W1991645801","https://openalex.org/W1997513136","https://openalex.org/W2005145064","https://openalex.org/W2008218598","https://openalex.org/W2010065712","https://openalex.org/W2025541974","https://openalex.org/W2025724838","https://openalex.org/W2027876233","https://openalex.org/W2030752355","https://openalex.org/W2041718188","https://openalex.org/W2042127712","https://openalex.org/W2054080602","https://openalex.org/W2058790494","https://openalex.org/W2063705045","https://openalex.org/W2065573007","https://openalex.org/W2073180766","https://openalex.org/W2075358805","https://openalex.org/W2075984213","https://openalex.org/W2084134413","https://openalex.org/W2087390451","https://openalex.org/W2087484001","https://openalex.org/W2087786743","https://openalex.org/W2128871544","https://openalex.org/W2132331298","https://openalex.org/W2137864764","https://openalex.org/W2319313545","https://openalex.org/W2346899756","https://openalex.org/W2414621672","https://openalex.org/W2544366261","https://openalex.org/W2581370604","https://openalex.org/W2620576835","https://openalex.org/W2756447448","https://openalex.org/W2771564791","https://openalex.org/W2794870136","https://openalex.org/W6639502355"],"related_works":["https://openalex.org/W4386748242","https://openalex.org/W2620576835","https://openalex.org/W3035375761","https://openalex.org/W1972798081","https://openalex.org/W2062193079","https://openalex.org/W2045872960","https://openalex.org/W3124078372","https://openalex.org/W2303248043","https://openalex.org/W2463771618","https://openalex.org/W3016559209"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-07-10T00:00:00"}