{"id":"https://openalex.org/W2811160288","doi":"https://doi.org/10.1093/biolre/ioy149","title":"Source and localization of ovulation-inducing factor/nerve growth factor in male reproductive tissues among mammalian species\u2020","display_name":"Source and localization of ovulation-inducing factor/nerve growth factor in male reproductive tissues among mammalian species\u2020","publication_year":2018,"publication_date":"2018-07-02","ids":{"openalex":"https://openalex.org/W2811160288","doi":"https://doi.org/10.1093/biolre/ioy149","mag":"2811160288","pmid":"https://pubmed.ncbi.nlm.nih.gov/29982342"},"language":"en","primary_location":{"id":"doi:10.1093/biolre/ioy149","doi":"https://doi.org/10.1093/biolre/ioy149","is_oa":false,"landing_page_url":"https://doi.org/10.1093/biolre/ioy149","pdf_url":null,"source":{"id":"https://openalex.org/S130598054","display_name":"Biology of Reproduction","issn_l":"0006-3363","issn":["0006-3363","1529-7268"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Reproduction","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109099427","display_name":"O. A. Bogle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32625721","display_name":"University of Saskatchewan","ror":"https://ror.org/010x8gc63","country_code":"CA","type":"education","lineage":["https://openalex.org/I32625721"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Orleigh A Bogle","raw_affiliation_strings":["Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada","institution_ids":["https://openalex.org/I32625721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048903903","display_name":"Rodrigo A. Carrasco","orcid":"https://orcid.org/0000-0002-4271-5544","observed_orcids":["https://orcid.org/0000-0002-4271-5544"]},"institutions":[{"id":"https://openalex.org/I32625721","display_name":"University of Saskatchewan","ror":"https://ror.org/010x8gc63","country_code":"CA","type":"education","lineage":["https://openalex.org/I32625721"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Rodrigo A Carrasco","raw_affiliation_strings":["Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"],"raw_orcid":"https://orcid.org/0000-0002-4271-5544","affiliations":[{"raw_affiliation_string":"Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada","institution_ids":["https://openalex.org/I32625721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077740211","display_name":"Marcelo H\u00e9ctor Ratto","orcid":"https://orcid.org/0000-0002-6072-7469","observed_orcids":["https://orcid.org/0000-0002-6072-7469"]},"institutions":[{"id":"https://openalex.org/I16465266","display_name":"Austral University of Chile","ror":"https://ror.org/029ycp228","country_code":"CL","type":"education","lineage":["https://openalex.org/I16465266"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Marcelo H Ratto","raw_affiliation_strings":["Department of Animal Science, Universidad Austral de Chile, Valdivia, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Science, Universidad Austral de Chile, Valdivia, Chile","institution_ids":["https://openalex.org/I16465266"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091177768","display_name":"Jaswant K. Singh","orcid":"https://orcid.org/0000-0002-6439-7831","observed_orcids":["https://orcid.org/0000-0002-6439-7831"]},"institutions":[{"id":"https://openalex.org/I32625721","display_name":"University of Saskatchewan","ror":"https://ror.org/010x8gc63","country_code":"CA","type":"education","lineage":["https://openalex.org/I32625721"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jaswant Singh","raw_affiliation_strings":["Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada","institution_ids":["https://openalex.org/I32625721"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050269562","display_name":"Gregory Paul Adams","orcid":"https://orcid.org/0000-0003-4207-2881","observed_orcids":["https://orcid.org/0000-0003-4207-2881"]},"institutions":[{"id":"https://openalex.org/I32625721","display_name":"University of Saskatchewan","ror":"https://ror.org/010x8gc63","country_code":"CA","type":"education","lineage":["https://openalex.org/I32625721"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Gregg P Adams","raw_affiliation_strings":["Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"],"raw_orcid":"https://orcid.org/0000-0003-4207-2881","affiliations":[{"raw_affiliation_string":"Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada","institution_ids":["https://openalex.org/I32625721"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5050269562"],"corresponding_institution_ids":["https://openalex.org/I32625721"],"apc_list":{"value":4605,"currency":"USD","value_usd":4605},"apc_paid":null,"fwci":3.3741,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.92330523,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"99","issue":"6","first_page":"1194","last_page":"1204"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.8920999765396118,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.8920999765396118,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10584","display_name":"Reproductive Physiology in Livestock","score":0.10050000250339508,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ovulation-inducing-factor","display_name":"ovulation-inducing factor","score":0.9679999947547913},{"id":"https://openalex.org/keywords/nerve-growth-factor","display_name":"nerve growth factor","score":0.9990000128746033},{"id":"https://openalex.org/keywords/male-reproductive-tissues","display_name":"male reproductive tissues","score":0.6000000238418579},{"id":"https://openalex.org/keywords/seminal-plasma","display_name":"seminal plasma","score":0.9539999961853027},{"id":"https://openalex.org/keywords/male-accessory-glands","display_name":"male accessory glands","score":0.7570000290870667},{"id":"https://openalex.org/keywords/prostate","display_name":"prostate","score":0.8820000290870667},{"id":"https://openalex.org/keywords/seminal-vesicle","display_name":"seminal vesicle","score":0.7639999985694885},{"id":"https://openalex.org/keywords/ampullae","display_name":"ampullae","score":0.9039999842643738},{"id":"https://openalex.org/keywords/ejaculate","display_name":"ejaculate","score":0.44699999690055847},{"id":"https://openalex.org/keywords/ovulation-induction","display_name":"ovulation induction","score":0.6859999895095825},{"id":"https://openalex.org/keywords/spontaneous-ovulation","display_name":"spontaneous ovulation","score":0.996999979019165},{"id":"https://openalex.org/keywords/camelids","display_name":"camelids","score":0.6809999942779541},{"id":"https://openalex.org/keywords/llama","display_name":"llamas","score":0.8019999861717224},{"id":"https://openalex.org/keywords/alpaca","display_name":"alpaca","score":0.8999999761581421},{"id":"https://openalex.org/keywords/bovidae","display_name":"Bovidae","score":0.8799999952316284},{"id":"https://openalex.org/keywords/deer","display_name":"deer","score":0.9900000095367432},{"id":"https://openalex.org/keywords/immunohistochemistry","display_name":"immunohistochemistry","score":0.5920000076293945}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8887015581130981},{"id":"https://openalex.org/C2778423431","wikidata":"https://www.wikidata.org/wiki/Q417782","display_name":"Nerve growth factor","level":3,"score":0.6571240425109863},{"id":"https://openalex.org/C176685330","wikidata":"https://www.wikidata.org/wiki/Q857638","display_name":"Radioimmunoassay","level":2,"score":0.6287153363227844},{"id":"https://openalex.org/C2778093475","wikidata":"https://www.wikidata.org/wiki/Q9715","display_name":"Semen","level":2,"score":0.567351222038269},{"id":"https://openalex.org/C2777702977","wikidata":"https://www.wikidata.org/wiki/Q187082","display_name":"Ovulation","level":3,"score":0.5525364279747009},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.4784424602985382},{"id":"https://openalex.org/C123765429","wikidata":"https://www.wikidata.org/wiki/Q36961","display_name":"Spermatogenesis","level":2,"score":0.4462057948112488},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.408937931060791},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39272570610046387},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3165283501148224},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.14738669991493225},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000906","descriptor_name":"Antibodies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005837","descriptor_name":"Genitalia, Male","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008322","descriptor_name":"Mammals","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012661","descriptor_name":"Semen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012661","descriptor_name":"Semen","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020932","descriptor_name":"Nerve Growth Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/biolre/ioy149","doi":"https://doi.org/10.1093/biolre/ioy149","is_oa":false,"landing_page_url":"https://doi.org/10.1093/biolre/ioy149","pdf_url":null,"source":{"id":"https://openalex.org/S130598054","display_name":"Biology of Reproduction","issn_l":"0006-3363","issn":["0006-3363","1529-7268"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Reproduction","raw_type":"journal-article"},{"id":"pmid:29982342","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29982342","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of reproduction","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320331517","display_name":"Nationale Genossenschaft f\u00fcr die Lagerung radioaktiver Abf\u00e4lle","ror":"https://ror.org/04gaaqn72"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W105117653","https://openalex.org/W627514673","https://openalex.org/W1514042206","https://openalex.org/W1965381491","https://openalex.org/W1970587959","https://openalex.org/W1974215491","https://openalex.org/W1984087305","https://openalex.org/W1985939288","https://openalex.org/W1990942696","https://openalex.org/W1992628413","https://openalex.org/W1994718549","https://openalex.org/W1995946464","https://openalex.org/W1996373676","https://openalex.org/W2006031962","https://openalex.org/W2006923280","https://openalex.org/W2009918823","https://openalex.org/W2014036333","https://openalex.org/W2019523470","https://openalex.org/W2020271609","https://openalex.org/W2020519503","https://openalex.org/W2021357124","https://openalex.org/W2029289040","https://openalex.org/W2041210562","https://openalex.org/W2042727575","https://openalex.org/W2052114697","https://openalex.org/W2054885425","https://openalex.org/W2068430071","https://openalex.org/W2072621978","https://openalex.org/W2079518963","https://openalex.org/W2079641290","https://openalex.org/W2081889560","https://openalex.org/W2085337096","https://openalex.org/W2089409361","https://openalex.org/W2089942034","https://openalex.org/W2091948183","https://openalex.org/W2095094748","https://openalex.org/W2099436722","https://openalex.org/W2103276585","https://openalex.org/W2113232007","https://openalex.org/W2115070926","https://openalex.org/W2118555287","https://openalex.org/W2134338516","https://openalex.org/W2139835720","https://openalex.org/W2143535428","https://openalex.org/W2149185574","https://openalex.org/W2149900710","https://openalex.org/W2151483038","https://openalex.org/W2156698011","https://openalex.org/W2161372295","https://openalex.org/W2162520402","https://openalex.org/W2244276231","https://openalex.org/W2532083518","https://openalex.org/W3105898142","https://openalex.org/W3141746762","https://openalex.org/W4240350114","https://openalex.org/W6808767617"],"related_works":["https://openalex.org/W2532083518","https://openalex.org/W2095094748","https://openalex.org/W1976840393","https://openalex.org/W3003600703","https://openalex.org/W2588231561","https://openalex.org/W7028856917","https://openalex.org/W2232940238","https://openalex.org/W2326945428","https://openalex.org/W2606621937","https://openalex.org/W2081889560"],"abstract_inverted_index":{"The":[0,181],"objectives":[1],"of":[2,12,29,32,48,69,85,91,131,183,253],"the":[3,8,25,41,65,83,88,118,124,128,136,147,166,232,251],"study":[4],"were":[5,109],"to":[6],"compare":[7],"presence":[9],"and":[10,23,35,75,82,94,98,105,121,139,144,146,149,154,158,221,238,244,258],"localization":[11],"ovulation-inducing":[13],"factor":[14,17],"(OIF)/nerve":[15],"growth":[16,164],"(NGF)":[18],"in":[19,27,56,87,116,134,141,151,165,189,209,241,250,255],"male":[20,66,233],"reproductive":[21,67],"organs":[22],"determine":[24],"abundance":[26,84,240],"ejaculates":[28,213],"species":[30],"representative":[31],"both":[33,117,256],"spontaneous":[34,259],"induced":[36,162,257],"ovulators.":[37,260],"We":[38],"hypothesized":[39],"that":[40,225],"protein":[42,230],"is":[43,53,227],"a":[44,228],"widely":[45],"conserved":[46],"component":[47],"semen":[49],"among":[50,236],"mammals,":[51],"but":[52,170],"most":[54],"abundant":[55],"camelids.":[57],"Immunohistochemical":[58],"analysis":[59],"was":[60,127,173,185,206],"performed":[61],"on":[62,114,217],"tissues":[63],"from":[64],"system":[68],"llamas,":[70,135],"rats,":[71],"cattle,":[72,96],"bison,":[73],"elk,":[74],"white-tailed":[76,155],"deer":[77],"(n":[78,100],"=":[79,101],"2":[80],"males/species),":[81],"OIF/NGF":[86,133,184,205,226],"seminal":[89,132,160,179,193],"plasma":[90,161,194],"camelids":[92],"(llamas":[93],"alpacas),":[95],"horses,":[97],"pigs":[99],"69,":[102],"53,":[103],"24,":[104],"16":[106],"ejaculates,":[107],"respectively)":[108],"quantified":[110],"by":[111,214],"radioimmunoassay.":[112,215],"Based":[113,216],"immunoreactivity":[115],"glandular":[119,122],"epithelium":[120],"lumen,":[123],"prostate":[125,150],"gland":[126,138],"main":[129],"source":[130],"vesicular":[137],"ampullae":[140,148],"bovids":[142],"(cattle":[143],"bison),":[145],"cervids":[152,245],"(elk":[153],"deer).":[156],"Camelid":[157],"bovine":[159,192],"dendritic":[163],"PC12":[167],"differentiation":[168],"bioassay,":[169],"no":[171],"effect":[172],"observed":[174],"with":[175],"equine":[176,210],"or":[177,211],"porcine":[178,212],"plasma.":[180],"concentration":[182],"10":[186],"times":[187],"higher":[188],"camelid":[190],"than":[191],"(1.2":[195],"\u00b1":[196,200],"0.21":[197],"vs.":[198],"0.10":[199],"0.03;":[201],"P":[202],"<":[203],"0.05);":[204],"not":[207],"detected":[208],"tissue":[218],"localization,":[219],"abundance,":[220],"bioactivity,":[222],"we":[223],"conclude":[224],"common":[229],"within":[231],"accessory":[234],"glands":[235],"species,":[237],"its":[239],"camelids,":[242],"bovids,":[243],"suggests":[246],"an":[247],"important":[248],"role":[249],"mechanisms":[252],"ovulation":[254]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-07-10T00:00:00"}