{"id":"https://openalex.org/W2811104241","doi":"https://doi.org/10.1016/j.jmbbm.2018.06.029","title":"An investigation on the correlation between the mechanical property change and the alterations in composition and microstructure of a porcine vascular tissue underwent trypsin-based decellularization treatment","display_name":"An investigation on the correlation between the mechanical property change and the alterations in composition and microstructure of a porcine vascular tissue underwent trypsin-based decellularization treatment","publication_year":2018,"publication_date":"2018-06-26","ids":{"openalex":"https://openalex.org/W2811104241","doi":"https://doi.org/10.1016/j.jmbbm.2018.06.029","mag":"2811104241","pmid":"https://pubmed.ncbi.nlm.nih.gov/29986294"},"language":"en","primary_location":{"id":"doi:10.1016/j.jmbbm.2018.06.029","doi":"https://doi.org/10.1016/j.jmbbm.2018.06.029","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jmbbm.2018.06.029","pdf_url":null,"source":{"id":"https://openalex.org/S100249163","display_name":"Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials","issn_l":"1751-6161","issn":["1751-6161","1878-0180"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Mechanical Behavior of Biomedical Materials","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100711335","display_name":"Chih\u2010Hsun Lin","orcid":"https://orcid.org/0000-0002-9771-5816","observed_orcids":["https://orcid.org/0000-0002-9771-5816"]},"institutions":[{"id":"https://openalex.org/I2803004286","display_name":"Taipei Veterans General Hospital","ror":"https://ror.org/03ymy8z76","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2803004286"]},{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chih-Hsun Lin","raw_affiliation_strings":["Division of Plastic Surgery, Department of Surgery, Taipei Veterans General Hospital, No. 201, Section 2, Shipai Rd., Beitou Dist., Taipei City 112, Taiwan, ROC; Department of Surgery, School of Medicine, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC","Department of Surgery, School of Medicine, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC","Division of Plastic Surgery, Department of Surgery, Taipei Veterans General Hospital, No. 201, Section 2, Shipai Rd., Beitou Dist., Taipei City 112, Taiwan, ROC"],"raw_orcid":"https://orcid.org/0000-0002-9771-5816","affiliations":[{"raw_affiliation_string":"Division of Plastic Surgery, Department of Surgery, Taipei Veterans General Hospital, No. 201, Section 2, Shipai Rd., Beitou Dist., Taipei City 112, Taiwan, ROC; Department of Surgery, School of Medicine, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC","institution_ids":["https://openalex.org/I2803004286","https://openalex.org/I4387156312"]},{"raw_affiliation_string":"Department of Surgery, School of Medicine, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC","institution_ids":["https://openalex.org/I4387156312"]},{"raw_affiliation_string":"Division of Plastic Surgery, Department of Surgery, Taipei Veterans General Hospital, No. 201, Section 2, Shipai Rd., Beitou Dist., Taipei City 112, Taiwan, ROC","institution_ids":["https://openalex.org/I2803004286"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027395511","display_name":"Yun-Chu Kao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yun-Chu Kao","raw_affiliation_strings":["Institute of Biomedical Engineering, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedical Engineering, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC","institution_ids":["https://openalex.org/I4387156312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112301806","display_name":"Hsu Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2803004286","display_name":"Taipei Veterans General Hospital","ror":"https://ror.org/03ymy8z76","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2803004286"]},{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Hsu Ma","raw_affiliation_strings":["Division of Plastic Surgery, Department of Surgery, Taipei Veterans General Hospital, No. 201, Section 2, Shipai Rd., Beitou Dist., Taipei City 112, Taiwan, ROC; Department of Surgery, School of Medicine, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC","Department of Surgery, School of Medicine, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC","Division of Plastic Surgery, Department of Surgery, Taipei Veterans General Hospital, No. 201, Section 2, Shipai Rd., Beitou Dist., Taipei City 112, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Plastic Surgery, Department of Surgery, Taipei Veterans General Hospital, No. 201, Section 2, Shipai Rd., Beitou Dist., Taipei City 112, Taiwan, ROC; Department of Surgery, School of Medicine, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC","institution_ids":["https://openalex.org/I2803004286","https://openalex.org/I4387156312"]},{"raw_affiliation_string":"Department of Surgery, School of Medicine, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC","institution_ids":["https://openalex.org/I4387156312"]},{"raw_affiliation_string":"Division of Plastic Surgery, Department of Surgery, Taipei Veterans General Hospital, No. 201, Section 2, Shipai Rd., Beitou Dist., Taipei City 112, Taiwan, ROC","institution_ids":["https://openalex.org/I2803004286"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110549963","display_name":"Ruey-Yug Tsay","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Ruey-Yug Tsay","raw_affiliation_strings":["Institute of Biomedical Engineering, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC; Center for Advanced Pharmaceutics and Drug Delivery Research, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC. Electronic address: tsay@ym.edu.tw","Center for Advanced Pharmaceutics and Drug Delivery Research, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC","Institute of Biomedical Engineering, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedical Engineering, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC; Center for Advanced Pharmaceutics and Drug Delivery Research, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC. Electronic address: tsay@ym.edu.tw","institution_ids":["https://openalex.org/I4387156312"]},{"raw_affiliation_string":"Center for Advanced Pharmaceutics and Drug Delivery Research, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC","institution_ids":["https://openalex.org/I4387156312"]},{"raw_affiliation_string":"Institute of Biomedical Engineering, National Yang-Ming University, No. 155, Section 2, Linong St., Beitou Dist., Taipei City 112, Taiwan, ROC","institution_ids":["https://openalex.org/I4387156312"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5110549963"],"corresponding_institution_ids":["https://openalex.org/I4387156312"],"apc_list":{"value":3690,"currency":"USD","value_usd":3690},"apc_paid":null,"fwci":3.6117,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.92888509,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"86","issue":null,"first_page":"199","last_page":"207"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11366","display_name":"Elasticity and Material Modeling","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/porcine-coronary-artery","display_name":"porcine coronary artery","score":0.9829999804496765},{"id":"https://openalex.org/keywords/vascular-grafts","display_name":"vascular grafts","score":0.718999981880188},{"id":"https://openalex.org/keywords/nonlinear-mechanical-properties","display_name":"nonlinear mechanical properties","score":0.43799999356269836},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.7289999723434448},{"id":"https://openalex.org/keywords/collagen-fibers","display_name":"collagen fibers","score":0.8180000185966492},{"id":"https://openalex.org/keywords/glycosaminoglycans","display_name":"glycosaminoglycans","score":0.9959999918937683},{"id":"https://openalex.org/keywords/stiffness-modulus","display_name":"stiffness modulus","score":0.675000011920929},{"id":"https://openalex.org/keywords/anisotropy","display_name":"anisotropy","score":0.6380000114440918},{"id":"https://openalex.org/keywords/tissue-microstructure","display_name":"tissue microstructure","score":0.5569999814033508}],"concepts":[{"id":"https://openalex.org/C190672674","wikidata":"https://www.wikidata.org/wiki/Q3866591","display_name":"Decellularization","level":3,"score":0.9924428462982178},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.6469073295593262},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.6095518469810486},{"id":"https://openalex.org/C87976508","wikidata":"https://www.wikidata.org/wiki/Q1498213","display_name":"Microstructure","level":2,"score":0.587907075881958},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5336573719978333},{"id":"https://openalex.org/C112950240","wikidata":"https://www.wikidata.org/wiki/Q76005","display_name":"Ultimate tensile strength","level":2,"score":0.5154060125350952},{"id":"https://openalex.org/C2780340462","wikidata":"https://www.wikidata.org/wiki/Q127450","display_name":"Trypsin","level":3,"score":0.47397416830062866},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.38124793767929077},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.33402764797210693},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.26606684923171997},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18010050058364868},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13222727179527283},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0969824492931366}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001696","descriptor_name":"Biomechanical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006025","descriptor_name":"Glycosaminoglycans","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014357","descriptor_name":"Trypsin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055595","descriptor_name":"Mechanical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jmbbm.2018.06.029","doi":"https://doi.org/10.1016/j.jmbbm.2018.06.029","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jmbbm.2018.06.029","pdf_url":null,"source":{"id":"https://openalex.org/S100249163","display_name":"Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials","issn_l":"1751-6161","issn":["1751-6161","1878-0180"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Mechanical Behavior of Biomedical Materials","raw_type":"journal-article"},{"id":"pmid:29986294","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29986294","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the mechanical behavior of biomedical materials","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4000000059604645,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323275","display_name":"National Yang-Ming University","ror":"https://ror.org/009h5ks85"},{"id":"https://openalex.org/F4320324696","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W178392116","https://openalex.org/W1532812722","https://openalex.org/W1966596110","https://openalex.org/W1987602789","https://openalex.org/W1994589849","https://openalex.org/W1996505814","https://openalex.org/W1997879864","https://openalex.org/W2004272412","https://openalex.org/W2008289317","https://openalex.org/W2010426476","https://openalex.org/W2017070241","https://openalex.org/W2024784597","https://openalex.org/W2025689238","https://openalex.org/W2032965689","https://openalex.org/W2036474604","https://openalex.org/W2042233722","https://openalex.org/W2045339683","https://openalex.org/W2056663971","https://openalex.org/W2058960248","https://openalex.org/W2061142495","https://openalex.org/W2068465081","https://openalex.org/W2073658538","https://openalex.org/W2081240810","https://openalex.org/W2083148170","https://openalex.org/W2085421725","https://openalex.org/W2087416032","https://openalex.org/W2089076087","https://openalex.org/W2093755261","https://openalex.org/W2093770019","https://openalex.org/W2100618331","https://openalex.org/W2112987844","https://openalex.org/W2116463491","https://openalex.org/W2118176349","https://openalex.org/W2119708685","https://openalex.org/W2129046072","https://openalex.org/W2131605870","https://openalex.org/W2147055134","https://openalex.org/W2154852947","https://openalex.org/W2268131265","https://openalex.org/W2482421968","https://openalex.org/W2521297810","https://openalex.org/W2912931721","https://openalex.org/W4230240787"],"related_works":["https://openalex.org/W2283304433","https://openalex.org/W2521297810","https://openalex.org/W2155537879","https://openalex.org/W2170498291","https://openalex.org/W2272631882","https://openalex.org/W2529117396","https://openalex.org/W2378464194","https://openalex.org/W2748915096","https://openalex.org/W7096548895","https://openalex.org/W2462124112"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":5}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-07-10T00:00:00"}