{"id":"https://openalex.org/W2810719013","doi":"https://doi.org/10.1093/europace/euy148","title":"Uninterrupted vs. interrupted periprocedural direct oral anticoagulants for catheter ablation of atrial fibrillation: a prospective randomized single-centre study on post-ablation thrombo-embolic and haemorrhagic events","display_name":"Uninterrupted vs. interrupted periprocedural direct oral anticoagulants for catheter ablation of atrial fibrillation: a prospective randomized single-centre study on post-ablation thrombo-embolic and haemorrhagic events","publication_year":2018,"publication_date":"2018-06-29","ids":{"openalex":"https://openalex.org/W2810719013","doi":"https://doi.org/10.1093/europace/euy148","mag":"2810719013","pmid":"https://pubmed.ncbi.nlm.nih.gov/29982562"},"language":"en","primary_location":{"id":"doi:10.1093/europace/euy148","doi":"https://doi.org/10.1093/europace/euy148","is_oa":false,"landing_page_url":"https://doi.org/10.1093/europace/euy148","pdf_url":null,"source":{"id":"https://openalex.org/S46732370","display_name":"EP Europace","issn_l":"1099-5129","issn":["1099-5129","1532-2092"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EP Europace","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052933365","display_name":"Kohki Nakamura","orcid":"https://orcid.org/0000-0002-9777-4592","observed_orcids":["https://orcid.org/0000-0002-9777-4592"]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kohki Nakamura","raw_affiliation_strings":["Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084857058","display_name":"Shigeto Naito","orcid":"https://orcid.org/0009-0006-7092-0445","observed_orcids":["https://orcid.org/0009-0006-7092-0445"]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigeto Naito","raw_affiliation_strings":["Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019098055","display_name":"Takehito Sasaki","orcid":"https://orcid.org/0000-0001-9139-2318","observed_orcids":["https://orcid.org/0000-0001-9139-2318"]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takehito Sasaki","raw_affiliation_strings":["Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020905581","display_name":"Yutaka Take","orcid":"https://orcid.org/0000-0001-5993-130X","observed_orcids":["https://orcid.org/0000-0001-5993-130X"]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yutaka Take","raw_affiliation_strings":["Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078910889","display_name":"Kentaro Minami","orcid":"https://orcid.org/0000-0002-0071-0673","observed_orcids":["https://orcid.org/0000-0002-0071-0673"]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kentaro Minami","raw_affiliation_strings":["Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104345245","display_name":"Yoshiyuki Kitagawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshiyuki Kitagawa","raw_affiliation_strings":["Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036672712","display_name":"Hiroyuki Motoda","orcid":"https://orcid.org/0000-0002-0044-1653","observed_orcids":["https://orcid.org/0000-0002-0044-1653"]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroyuki Motoda","raw_affiliation_strings":["Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056741248","display_name":"Mitsuho Inoue","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mitsuho Inoue","raw_affiliation_strings":["Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103811841","display_name":"Yoshimitsu Otsuka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshimitsu Otsuka","raw_affiliation_strings":["Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042239218","display_name":"Katsura Niijima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsura Niijima","raw_affiliation_strings":["Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052778471","display_name":"Eiji Yamashita","orcid":"https://orcid.org/0000-0002-7302-3866","observed_orcids":["https://orcid.org/0000-0002-7302-3866"]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Eiji Yamashita","raw_affiliation_strings":["Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061285728","display_name":"Yoshinao Sugai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshinao Sugai","raw_affiliation_strings":["Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004090521","display_name":"Koji Kumagai","orcid":"https://orcid.org/0000-0003-1880-1175","observed_orcids":["https://orcid.org/0000-0003-1880-1175"]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Koji Kumagai","raw_affiliation_strings":["Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111376862","display_name":"Keiko Koyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Keiko Koyama","raw_affiliation_strings":["Division of Radiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Radiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049670987","display_name":"Nobusada Funabashi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobusada Funabashi","raw_affiliation_strings":["Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba City, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba City, Chiba, Japan","institution_ids":["https://openalex.org/I159385669"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064010379","display_name":"Shigeru Oshima","orcid":"https://orcid.org/0000-0003-1186-9177","observed_orcids":["https://orcid.org/0000-0003-1186-9177","https://orcid.org/0000-0001-9929-5336"]},"institutions":[{"id":"https://openalex.org/I4210129341","display_name":"Gunma Prefectural Cardiovascular Center","ror":"https://ror.org/037403209","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129341"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigeru Oshima","raw_affiliation_strings":["Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi City, Gunma, Japan","institution_ids":["https://openalex.org/I4210129341"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5052933365"],"corresponding_institution_ids":["https://openalex.org/I4210129341"],"apc_list":{"value":4344,"currency":"EUR","value_usd":4909},"apc_paid":null,"fwci":6.6146,"has_fulltext":false,"cited_by_count":67,"citation_normalized_percentile":{"value":0.97687248,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"21","issue":"2","first_page":"259","last_page":"267"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11217","display_name":"Cardiac Arrhythmias and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/direct-oral-anticoagulants","display_name":"direct oral anticoagulants","score":0.9490000009536743},{"id":"https://openalex.org/keywords/periprocedural-anticoagulation","display_name":"periprocedural anticoagulation","score":0.9580000042915344},{"id":"https://openalex.org/keywords/catheter-ablation","display_name":"catheter ablation","score":0.8090000152587891},{"id":"https://openalex.org/keywords/non-valvular-atrial-fibrillation","display_name":"non-valvular atrial fibrillation","score":0.9940000176429749},{"id":"https://openalex.org/keywords/thromboembolism","display_name":"thromboembolism","score":0.859000027179718},{"id":"https://openalex.org/keywords/major-bleeding","display_name":"major bleeding","score":0.9589999914169312},{"id":"https://openalex.org/keywords/transient-ischemic-attack","display_name":"transient ischemic attack","score":0.9190000295639038}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9812842607498169},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.7455755472183228},{"id":"https://openalex.org/C2778902805","wikidata":"https://www.wikidata.org/wiki/Q322177","display_name":"Ablation","level":2,"score":0.6771805286407471},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.6725398302078247},{"id":"https://openalex.org/C2776131983","wikidata":"https://www.wikidata.org/wiki/Q436572","display_name":"Catheter ablation","level":3,"score":0.6301652193069458},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6119795441627502},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5815001130104065},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.5276654362678528},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5198774337768555},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.4691818058490753},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.44615039229393005},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4128724932670593},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000991","descriptor_name":"Antithrombins","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000991","descriptor_name":"Antithrombins","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D002546","descriptor_name":"Ischemic Attack, Transient","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D002546","descriptor_name":"Ischemic Attack, Transient","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D002546","descriptor_name":"Ischemic Attack, Transient","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D004334","descriptor_name":"Drug Administration Schedule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013923","descriptor_name":"Thromboembolism","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D013923","descriptor_name":"Thromboembolism","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D013923","descriptor_name":"Thromboembolism","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017115","descriptor_name":"Catheter Ablation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D065427","descriptor_name":"Factor Xa Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/europace/euy148","doi":"https://doi.org/10.1093/europace/euy148","is_oa":false,"landing_page_url":"https://doi.org/10.1093/europace/euy148","pdf_url":null,"source":{"id":"https://openalex.org/S46732370","display_name":"EP Europace","issn_l":"1099-5129","issn":["1099-5129","1532-2092"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EP Europace","raw_type":"journal-article"},{"id":"pmid:29982562","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29982562","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1514897206","https://openalex.org/W1595057647","https://openalex.org/W1967591080","https://openalex.org/W1968678408","https://openalex.org/W1980921198","https://openalex.org/W1994028806","https://openalex.org/W2022219945","https://openalex.org/W2031570748","https://openalex.org/W2074982436","https://openalex.org/W2120775803","https://openalex.org/W2121902831","https://openalex.org/W2131568644","https://openalex.org/W2167850919","https://openalex.org/W2195469064","https://openalex.org/W2276809808","https://openalex.org/W2282937275","https://openalex.org/W2323432212","https://openalex.org/W2331433835","https://openalex.org/W2546819700","https://openalex.org/W2560335030","https://openalex.org/W2595627091","https://openalex.org/W2617377817","https://openalex.org/W3023357416","https://openalex.org/W4241261201","https://openalex.org/W6737518082"],"related_works":["https://openalex.org/W3156136400","https://openalex.org/W4387653474","https://openalex.org/W2885010159","https://openalex.org/W2981364916","https://openalex.org/W6901745389","https://openalex.org/W2811266010","https://openalex.org/W3098864754","https://openalex.org/W2803973634","https://openalex.org/W3006597859","https://openalex.org/W2977826779"],"abstract_inverted_index":{"AIMS:":[0],"This":[1],"prospective,":[2],"randomized,":[3],"single-centre":[4],"study":[5],"aimed":[6],"to":[7,48,50],"directly":[8],"compare":[9],"the":[10,61,64,67,86,108,125,149,175,220],"safety":[11],"and":[12,16,78,92,95,97,117,122,131,143,186,202,222,233,237,242,246],"efficacy":[13],"of":[14,31,60,66,75,107,124,141,174,194,204,230,240],"uninterrupted":[15,109,185,221],"interrupted":[17,126,187,223],"periprocedural":[18,251],"anticoagulation":[19,252],"protocols":[20,225],"with":[21,206],"direct":[22],"oral":[23],"anticoagulants":[24],"(DOACs)":[25],"in":[26,105,171,253],"patients":[27,44,177,255],"undergoing":[28,178,256],"catheter":[29,257],"ablation":[30,49],"non-valvular":[32],"atrial":[33],"fibrillation":[34],"(NVAF).":[35],"METHODS":[36],"AND":[37],"RESULTS:":[38],"We":[39],"randomly":[40],"assigned":[41],"846":[42],"NVAF":[43,254],"receiving":[45],"DOACs":[46,62],"prior":[47],"uninterruption":[51],"(n":[52,57],"=":[53,58,137,156,162,200,216],"422)":[54],"or":[55],"interruption":[56],"424)":[59],"on":[63,208],"day":[65],"procedure.":[68],"The":[69,101,139,184],"primary":[70,102],"endpoint":[71,103],"was":[72,146],"a":[73,191,227],"composite":[74],"symptomatic":[76,91,231],"thromboembolisms":[77,94,232],"major":[79,96,119,133,142,234],"bleeding":[80,99,120,134,145,235,244],"events":[81,236,245],"within":[82],"30":[83],"days":[84],"after":[85],"ablation.":[87,258],"Secondary":[88],"endpoints":[89],"included":[90],"silent":[93],"minor":[98,144,243],"events.":[100],"occurred":[104],"0.7%":[106],"DOAC":[110,127,188,224],"group":[111,128],"[1":[112],"transient":[113],"ischaemic":[114,166],"attack":[115],"(TIA)":[116],"2":[118],"events]":[121],"1.2%":[123],"(1":[129],"TIA":[130],"4":[132],"events)":[135],"(P":[136],"0.480).":[138],"incidence":[140,193,239],"comparable":[147],"between":[148],"two":[150],"groups":[151,189],"(0.5%":[152],"vs.":[153,159,197,213],"0.9%,":[154],"P":[155,161,199,215],"0.345;":[157],"5.9%":[158],"5.4%,":[160],"0.753).":[163],"Silent":[164],"cerebral":[165],"lesions":[167],"(SCILs)":[168],"were":[169],"observed":[170],"138":[172],"(20.9%)":[173],"661":[176],"post-ablation":[179],"magnetic":[180],"resonance":[181],"(MR)":[182],"imaging.":[183],"revealed":[190,226],"similar":[192,238],"SCILs":[195,205,241],"(19.8%":[196],"22.0%,":[198],"0.484)":[201],"percentage":[203],"disappearance":[207],"follow-up":[209],"MR":[210],"imaging":[211],"(77.8%":[212],"82.1%,":[214],"0.428).":[217],"CONCLUSION:":[218],"Both":[219],"low":[228],"risk":[229],"may":[247],"be":[248],"feasible":[249],"for":[250]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":17},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-07-10T00:00:00"}