{"id":"https://openalex.org/W2809909333","doi":"https://doi.org/10.1111/ppe.12485","title":"Concentrations of immune marker in newborn dried blood spots and early childhood development: Results from the Upstate KIDS Study","display_name":"Concentrations of immune marker in newborn dried blood spots and early childhood development: Results from the Upstate KIDS Study","publication_year":2018,"publication_date":"2018-07-01","ids":{"openalex":"https://openalex.org/W2809909333","doi":"https://doi.org/10.1111/ppe.12485","mag":"2809909333","pmid":"https://pubmed.ncbi.nlm.nih.gov/29972605","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6763275"},"language":"en","primary_location":{"id":"doi:10.1111/ppe.12485","doi":"https://doi.org/10.1111/ppe.12485","is_oa":false,"landing_page_url":"https://doi.org/10.1111/ppe.12485","pdf_url":null,"source":{"id":"https://openalex.org/S134018196","display_name":"Paediatric and Perinatal Epidemiology","issn_l":"0269-5022","issn":["0269-5022","1365-3016"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Paediatric and Perinatal Epidemiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6763275","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049419096","display_name":"Akhgar Ghassabian","orcid":"https://orcid.org/0000-0001-9551-4706","observed_orcids":["https://orcid.org/0000-0001-9551-4706"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Akhgar Ghassabian","raw_affiliation_strings":["Departments of Pediatrics, Environmental Medicine, and Population Health, New York University School of Medicine, New York, NY, USA","Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":"https://orcid.org/0000-0001-9551-4706","affiliations":[{"raw_affiliation_string":"Departments of Pediatrics, Environmental Medicine, and Population Health, New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062173537","display_name":"Rajeshwari Sundaram","orcid":"https://orcid.org/0000-0002-6918-5002","observed_orcids":["https://orcid.org/0000-0002-6918-5002"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rajeshwari Sundaram","raw_affiliation_strings":["Biostatistics and Bioinformatics Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biostatistics and Bioinformatics Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108273181","display_name":"Nikhita Chahal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nikhita Chahal","raw_affiliation_strings":["Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051069727","display_name":"Alexander C. McLain","orcid":"https://orcid.org/0000-0002-5475-0670","observed_orcids":["https://orcid.org/0000-0002-5475-0670"]},"institutions":[{"id":"https://openalex.org/I155781252","display_name":"University of South Carolina","ror":"https://ror.org/02b6qw903","country_code":"US","type":"education","lineage":["https://openalex.org/I155781252"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander C. McLain","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA"],"raw_orcid":"https://orcid.org/0000-0002-5475-0670","affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA","institution_ids":["https://openalex.org/I155781252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039460160","display_name":"Erin M. Bell","orcid":"https://orcid.org/0000-0002-5723-7581","observed_orcids":["https://orcid.org/0000-0002-5723-7581"]},"institutions":[{"id":"https://openalex.org/I392282","display_name":"University at Albany, State University of New York","ror":"https://ror.org/012zs8222","country_code":"US","type":"education","lineage":["https://openalex.org/I392282"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erin M. Bell","raw_affiliation_strings":["Department of Environmental Health Sciences, University at Albany School of Public Health, Albany, NY, USA","Department of Epidemiology and Biostatistics, University at Albany School of Public Health, Albany, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Health Sciences, University at Albany School of Public Health, Albany, NY, USA","institution_ids":["https://openalex.org/I392282"]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, University at Albany School of Public Health, Albany, NY, USA","institution_ids":["https://openalex.org/I392282"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053216437","display_name":"David A. Lawrence","orcid":"https://orcid.org/0000-0002-8940-9640","observed_orcids":["https://orcid.org/0000-0002-8940-9640"]},"institutions":[{"id":"https://openalex.org/I1298060332","display_name":"New York State Department of Health","ror":"https://ror.org/04hf5kq57","country_code":"US","type":"government","lineage":["https://openalex.org/I1298060332"]},{"id":"https://openalex.org/I1339417872","display_name":"Wadsworth Center","ror":"https://ror.org/050kf9c55","country_code":"US","type":"facility","lineage":["https://openalex.org/I1298060332","https://openalex.org/I1339417872"]},{"id":"https://openalex.org/I392282","display_name":"University at Albany, State University of New York","ror":"https://ror.org/012zs8222","country_code":"US","type":"education","lineage":["https://openalex.org/I392282"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David A. Lawrence","raw_affiliation_strings":["Department of Environmental Health Sciences, University at Albany School of Public Health, Albany, NY, USA","Wadsworth Center, New York State Department of Health, Albany, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Health Sciences, University at Albany School of Public Health, Albany, NY, USA","institution_ids":["https://openalex.org/I392282"]},{"raw_affiliation_string":"Wadsworth Center, New York State Department of Health, Albany, NY, USA","institution_ids":["https://openalex.org/I1298060332","https://openalex.org/I1339417872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037209415","display_name":"Stephen E. Gilman","orcid":"https://orcid.org/0000-0002-8331-6419","observed_orcids":["https://orcid.org/0000-0002-8331-6419"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen E. Gilman","raw_affiliation_strings":["Department of Mental Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA","Health Behavior Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mental Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Health Behavior Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015889001","display_name":"Edwina H. Yeung","orcid":"https://orcid.org/0000-0002-3851-2613","observed_orcids":["https://orcid.org/0000-0002-3851-2613"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edwina H. Yeung","raw_affiliation_strings":["Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":"https://orcid.org/0000-0002-3851-2613","affiliations":[{"raw_affiliation_string":"Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5049419096"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228","https://openalex.org/I57206974"],"apc_list":{"value":4770,"currency":"USD","value_usd":4770},"apc_paid":null,"fwci":0.3152,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.42925278,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"32","issue":"4","first_page":"337","last_page":"345"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.2703000009059906,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.2703000009059906,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11060","display_name":"Infant Development and Preterm Care","score":0.19820000231266022,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.10869999974966049,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immune-markers","display_name":"immunological markers","score":0.9359999895095825},{"id":"https://openalex.org/keywords/early-childhood-development","display_name":"early childhood development","score":0.8009999990463257},{"id":"https://openalex.org/keywords/developmental-delay","display_name":"developmental delay","score":0.9909999966621399},{"id":"https://openalex.org/keywords/pdgf-aa","display_name":"PDGF-AA","score":0.9470000267028809},{"id":"https://openalex.org/keywords/plasminogen-activator-inhibitor-1","display_name":"plasminogen activator inhibitor-1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cxcl12","display_name":"CXCL12","score":0.9309999942779541},{"id":"https://openalex.org/keywords/macrophage-inflammatory-protein-1beta","display_name":"macrophage inflammatory protein-1\u03b2","score":0.972000002861023},{"id":"https://openalex.org/keywords/cytokine-dysregulation","display_name":"cytokine imbalance","score":0.8299999833106995}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.854911744594574},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6623548865318298},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5030145049095154},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4986569881439209},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.43227121233940125},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.40971750020980835},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.36424142122268677},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3419938087463379},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3267483115196228},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08215272426605225},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002490","descriptor_name":"Central Nervous System","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D002657","descriptor_name":"Child Development","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002658","descriptor_name":"Developmental Disabilities","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002658","descriptor_name":"Developmental Disabilities","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009518","descriptor_name":"New York","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1111/ppe.12485","doi":"https://doi.org/10.1111/ppe.12485","is_oa":false,"landing_page_url":"https://doi.org/10.1111/ppe.12485","pdf_url":null,"source":{"id":"https://openalex.org/S134018196","display_name":"Paediatric and Perinatal Epidemiology","issn_l":"0269-5022","issn":["0269-5022","1365-3016"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Paediatric and Perinatal Epidemiology","raw_type":"journal-article"},{"id":"pmid:29972605","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29972605","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Paediatric and perinatal epidemiology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5733308","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6763275","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6763275","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6763275","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Paediatr Perinat Epidemiol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5733308","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6763275","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1594460571","display_name":null,"funder_award_id":"HHSN267200700019C","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G2719412891","display_name":null,"funder_award_id":"HHSN275201200005C","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G9000878187","display_name":"Upstate KIDS Follow-Up Study","funder_award_id":"ZIAHD008949","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1548396511","https://openalex.org/W1904696976","https://openalex.org/W1971598496","https://openalex.org/W1991996969","https://openalex.org/W2004265420","https://openalex.org/W2021539557","https://openalex.org/W2021963251","https://openalex.org/W2022385941","https://openalex.org/W2022438517","https://openalex.org/W2024526798","https://openalex.org/W2032696713","https://openalex.org/W2048843644","https://openalex.org/W2062117677","https://openalex.org/W2069809946","https://openalex.org/W2079318458","https://openalex.org/W2092930185","https://openalex.org/W2105494350","https://openalex.org/W2108973483","https://openalex.org/W2122187802","https://openalex.org/W2131528206","https://openalex.org/W2145000720","https://openalex.org/W2154188802","https://openalex.org/W2158220663","https://openalex.org/W2188493632","https://openalex.org/W2226700671","https://openalex.org/W2238920788","https://openalex.org/W2279762554","https://openalex.org/W2338014412","https://openalex.org/W2521057789","https://openalex.org/W2545369127","https://openalex.org/W2563700932","https://openalex.org/W2601009846","https://openalex.org/W2625925685","https://openalex.org/W2738244128","https://openalex.org/W2793955647"],"related_works":["https://openalex.org/W3215205139","https://openalex.org/W2946731554","https://openalex.org/W6982392804","https://openalex.org/W1409858176","https://openalex.org/W4413799112","https://openalex.org/W2154188802","https://openalex.org/W2398705534","https://openalex.org/W6888578326","https://openalex.org/W1981091499","https://openalex.org/W4376133068"],"abstract_inverted_index":{"BACKGROUND:":[0],"Evidence":[1],"shows":[2],"cytokine":[3],"dysregulation":[4],"in":[5,61,125,225,234,250],"children":[6,80,96],"with":[7,122,191,213,231],"developmental":[8,99,214,232,248],"disabilities.":[9],"The":[10,197],"association":[11],"between":[12,30],"immune":[13,34,52,118],"activity":[14],"during":[15],"the":[16,28,72,235],"perinatal":[17],"period":[18],"and":[19,36,88,110,179],"child":[20,37,111],"development":[21],"is":[22],"less":[23],"clear.":[24],"METHODS:":[25],"We":[26,101],"examined":[27],"relationship":[29],"newborn":[31,62],"concentrations":[32,224,239],"of":[33,135,146,194,240,247],"markers":[35,119],"development.":[38],"Within":[39],"Upstate":[40],"KIDS,":[41],"a":[42],"population-based":[43],"birth":[44],"cohort":[45],"(2008-2010,":[46],"upstate":[47],"New":[48],"York),":[49],"we":[50,141],"assayed":[51],"markers,":[53,148],"which":[54],"are":[55],"postulated":[56],"to":[57,113],"have":[58],"neuro-modulatory":[59],"effects,":[60],"dried":[63],"blood":[64],"spots":[65],"(NDBS,":[66],"n":[67],"=":[68],"3038).":[69],"Mothers":[70],"completed":[71],"Ages":[73],"&":[74],"Stages":[75],"Questionnaire\u00a9":[76],"(ASQ)":[77],"for":[78,108,204,210],"their":[79,95],"repeatedly":[81],"through":[82],"age":[83],"36":[84,89],"months.":[85],"At":[86],"30":[87],"months,":[90],"mothers":[91],"also":[92],"reported":[93],"whether":[94],"received":[97],"any":[98],"services.":[100],"used":[102],"generalised":[103],"linear":[104],"mixed":[105],"models":[106],"adjusted":[107],"maternal":[109],"characteristics":[112],"test":[114],"associations.":[115],"RESULTS:":[116],"Sixteen":[117],"were":[120,189],"associated":[121,190,230],"failing":[123],"ASQ":[124,195],"unadjusted":[126],"models.":[127],"After":[128],"full":[129],"adjustment":[130],"(for":[131],"gestational":[132],"age,":[133],"mode":[134],"delivery,":[136],"parity,":[137],"pregnancy":[138],"smoking,":[139],"etc.),":[140],"observed":[142],"that":[143],"higher":[144],"levels":[145],"4":[147],"including":[149],"platelet-derived":[150],"growth":[151,241],"factor-AA":[152],"(PDGF-AA,":[153],"OR":[154],"0.77,":[155,187],"95%":[156,165,175,185],"CI":[157,166,176,186],"0.67,":[158],"0.89),":[159],"plasminogen":[160],"activator":[161],"inhibitor-1":[162],"(OR":[163,173,183],"0.80,":[164],"0.68,":[167],"0.94),":[168],"stromal":[169],"cell":[170],"derived":[171],"factor-1":[172],"0.85,":[174],"0.73,":[177],"0.98),":[178],"macrophage":[180],"inflammatory":[181],"protein-1beta":[182],"0.87,":[184],"0.98)":[188],"lower":[192],"odds":[193],"failure.":[196],"associations":[198],"did":[199],"not":[200,228],"exist":[201],"if":[202],"correction":[203],"multiple":[205],"comparisons":[206],"was":[207],"performed,":[208],"except":[209],"PDGF-AA.":[211],"Analyses":[212],"service":[215],"use":[216],"revealed":[217],"similar":[218],"null":[219],"findings.":[220],"CONCLUSIONS:":[221],"Immune":[222],"marker":[223],"NDBS":[226],"may":[227,244],"be":[229,245],"delay":[233,249],"general":[236],"population.":[237],"Newborn":[238],"factor":[242],"PDGF-AA":[243],"protective":[246],"childhood.":[251]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-07-10T00:00:00"}