{"id":"https://openalex.org/W2809521387","doi":null,"title":"The Urinary Proteome Reflects Proximal Tubule Stress In Type-1 Diabetics With Microalbuminuria and Early Renal Function Decline","display_name":"The Urinary Proteome Reflects Proximal Tubule Stress In Type-1 Diabetics With Microalbuminuria and Early Renal Function Decline","publication_year":2009,"publication_date":"2009-04-30","ids":{"openalex":"https://openalex.org/W2809521387","mag":"2809521387"},"language":"en","primary_location":{"id":"mag:2809521387","doi":null,"is_oa":false,"landing_page_url":"https://www.rti.org/publication/urinary-proteome-reflects-proximal-tubule-stress-type-1-diabetics-microalbuminuria-and","pdf_url":null,"source":{"id":"https://openalex.org/S115693375","display_name":"Journal of the American Society of Nephrology","issn_l":"1046-6673","issn":["1046-6673","1533-3450"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315620","host_organization_name":"American Society of Nephrology","host_organization_lineage":["https://openalex.org/P4310315620"],"host_organization_lineage_names":["American Society of Nephrology"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of the American Society of Nephrology","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003621767","display_name":"John P. Klein","orcid":"https://orcid.org/0000-0001-7778-2467","observed_orcids":["https://orcid.org/0000-0001-7778-2467"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John P. Klein","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7778-2467","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075863437","display_name":"Andrzej S. Kr\u00f3lewski","orcid":"https://orcid.org/0000-0002-1705-2953","observed_orcids":["https://orcid.org/0000-0002-1705-2953"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrzej S. Kr\u00f3lewski","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1705-2953","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024422384","display_name":"James H. Warram","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"James H. Warram","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042356850","display_name":"Brad H. Rovin","orcid":"https://orcid.org/0000-0001-5639-0210","observed_orcids":["https://orcid.org/0000-0001-5639-0210"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brad H. Rovin","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5639-0210","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039501195","display_name":"Grier P. Page","orcid":"https://orcid.org/0000-0003-2582-3786","observed_orcids":["https://orcid.org/0000-0003-2582-3786"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Grier P. Page","raw_affiliation_strings":["BiostatEpi VPO"],"raw_orcid":"https://orcid.org/0000-0003-2582-3786","affiliations":[{"raw_affiliation_string":"BiostatEpi VPO","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083574472","display_name":"Clinton C. Bertram","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Clinton C. Bertram","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017157522","display_name":"Daniel Wade Wilkey","orcid":"https://orcid.org/0000-0001-7491-7696","observed_orcids":["https://orcid.org/0000-0001-7491-7696"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel W. Wilkey","raw_affiliation_strings":["BiostatEpi VPO"],"raw_orcid":"https://orcid.org/0000-0001-7491-7696","affiliations":[{"raw_affiliation_string":"BiostatEpi VPO","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060304369","display_name":"Linda Ficociello","orcid":"https://orcid.org/0000-0003-3523-0028","observed_orcids":["https://orcid.org/0000-0003-3523-0028"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Linda Ficociello","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3523-0028","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000841344","display_name":"Bruce A. Perkins","orcid":"https://orcid.org/0000-0002-5885-0046","observed_orcids":["https://orcid.org/0000-0002-5885-0046"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bruce A. Perkins","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5885-0046","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007173298","display_name":"Grzegorz M. Boratyn","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Grzegorz M. Boratyn","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5085061817","display_name":"Michael L. Merchant","orcid":"https://orcid.org/0000-0003-4128-4057","observed_orcids":["https://orcid.org/0000-0003-4128-4057"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael L. Merchant","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4128-4057","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.44456067,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.02419999986886978,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/urinary-proteome","display_name":"urinary proteome","score":0.996999979019165},{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.9850000143051147},{"id":"https://openalex.org/keywords/microalbuminuria","display_name":"microalbuminuria","score":0.9380000233650208},{"id":"https://openalex.org/keywords/diabetic-nephropathy","display_name":"diabetic nephropathy","score":0.8420000076293945},{"id":"https://openalex.org/keywords/kidney-injury-biomarkers","display_name":"kidney injury biomarkers","score":0.6620000004768372}],"concepts":[{"id":"https://openalex.org/C2781203188","wikidata":"https://www.wikidata.org/wiki/Q1676817","display_name":"Microalbuminuria","level":3,"score":0.8839892148971558},{"id":"https://openalex.org/C3018884230","wikidata":"https://www.wikidata.org/wiki/Q58184","display_name":"Renal tubule","level":3,"score":0.6082948446273804},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.565772533416748},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.5587685704231262},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5518768429756165},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.5515149831771851},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4821600317955017},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.47958746552467346},{"id":"https://openalex.org/C2780222010","wikidata":"https://www.wikidata.org/wiki/Q2916078","display_name":"Proximal tubule","level":3,"score":0.4617147445678711},{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.4190441966056824},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.3163696825504303},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2615644335746765},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.18120983242988586}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2809521387","doi":null,"is_oa":false,"landing_page_url":"https://www.rti.org/publication/urinary-proteome-reflects-proximal-tubule-stress-type-1-diabetics-microalbuminuria-and","pdf_url":null,"source":{"id":"https://openalex.org/S115693375","display_name":"Journal of the American Society of Nephrology","issn_l":"1046-6673","issn":["1046-6673","1533-3450"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315620","host_organization_name":"American Society of Nephrology","host_organization_lineage":["https://openalex.org/P4310315620"],"host_organization_lineage_names":["American Society of Nephrology"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of the American Society of Nephrology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2260377490","https://openalex.org/W436165740","https://openalex.org/W2098129643","https://openalex.org/W4250517515","https://openalex.org/W4394963320","https://openalex.org/W4254650730","https://openalex.org/W7119260900","https://openalex.org/W7097874902","https://openalex.org/W2568796146","https://openalex.org/W2610513533"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2018-06-29T00:00:00"}