{"id":"https://openalex.org/W2809511074","doi":"https://doi.org/10.1016/j.coi.2018.06.001","title":"Acquired and genetic host susceptibility factors and microbial pathogenic factors that predispose to nontuberculous mycobacterial infections","display_name":"Acquired and genetic host susceptibility factors and microbial pathogenic factors that predispose to nontuberculous mycobacterial infections","publication_year":2018,"publication_date":"2018-06-21","ids":{"openalex":"https://openalex.org/W2809511074","doi":"https://doi.org/10.1016/j.coi.2018.06.001","mag":"2809511074","pmid":"https://pubmed.ncbi.nlm.nih.gov/29936307"},"language":"en","primary_location":{"id":"doi:10.1016/j.coi.2018.06.001","doi":"https://doi.org/10.1016/j.coi.2018.06.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.coi.2018.06.001","pdf_url":null,"source":{"id":"https://openalex.org/S170047187","display_name":"Current Opinion in Immunology","issn_l":"0952-7915","issn":["0952-7915","1879-0372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Immunology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043134219","display_name":"Jennifer R. Honda","orcid":"https://orcid.org/0000-0002-4943-8738","observed_orcids":["https://orcid.org/0000-0002-4943-8738"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jennifer R Honda","raw_affiliation_strings":["Department of Biomedical Research, United States; Center for Genes, Environment, and Health, United States","Center for Genes, Environment, and Health, United States","Department of Biomedical Research, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Research, United States; Center for Genes, Environment, and Health, United States","institution_ids":[]},{"raw_affiliation_string":"Center for Genes, Environment, and Health, United States","institution_ids":[]},{"raw_affiliation_string":"Department of Biomedical Research, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018237157","display_name":"Scott Alper","orcid":"https://orcid.org/0000-0002-2411-2037","observed_orcids":["https://orcid.org/0000-0002-2411-2037"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott Alper","raw_affiliation_strings":["Department of Biomedical Research, United States; Center for Genes, Environment, and Health, United States; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States","Center for Genes, Environment, and Health, United States","Department of Biomedical Research, United States","Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Research, United States; Center for Genes, Environment, and Health, United States; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States","institution_ids":["https://openalex.org/I51713134"]},{"raw_affiliation_string":"Center for Genes, Environment, and Health, United States","institution_ids":[]},{"raw_affiliation_string":"Department of Biomedical Research, United States","institution_ids":[]},{"raw_affiliation_string":"Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111823615","display_name":"Xiyuan Bai","orcid":"https://orcid.org/0009-0004-8152-4195","observed_orcids":["https://orcid.org/0009-0004-8152-4195"]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiyuan Bai","raw_affiliation_strings":["Medicine and Academic Affairs, National Jewish Health, Denver, CO, United States; Division of Pulmonary Sciences and Critical Care Medicine, United States","Division of Pulmonary Sciences and Critical Care Medicine, United States","Medicine and Academic Affairs, National Jewish Health, Denver, CO, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine and Academic Affairs, National Jewish Health, Denver, CO, United States; Division of Pulmonary Sciences and Critical Care Medicine, United States","institution_ids":["https://openalex.org/I3019586173"]},{"raw_affiliation_string":"Division of Pulmonary Sciences and Critical Care Medicine, United States","institution_ids":[]},{"raw_affiliation_string":"Medicine and Academic Affairs, National Jewish Health, Denver, CO, United States","institution_ids":["https://openalex.org/I3019586173"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044041242","display_name":"Edward D. Chan","orcid":"https://orcid.org/0000-0001-7612-7727","observed_orcids":["https://orcid.org/0000-0001-7612-7727"]},"institutions":[{"id":"https://openalex.org/I3019586173","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019586173"]},{"id":"https://openalex.org/I4210101549","display_name":"Denver VA Medical Center","ror":"https://ror.org/018hk2b97","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210101549","https://openalex.org/I4210113540","https://openalex.org/I4210148403"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Edward D Chan","raw_affiliation_strings":["Medicine and Academic Affairs, National Jewish Health, Denver, CO, United States; Department of Medicine, Denver Veterans Affairs Medical Center, Denver, CO, United States; Division of Pulmonary Sciences and Critical Care Medicine, United States. Electronic address: ChanE@NJHealth.org","Department of Medicine, Denver Veterans Affairs Medical Center, Denver, CO, United States","Division of Pulmonary Sciences and Critical Care Medicine, United States","Medicine and Academic Affairs, National Jewish Health, Denver, CO, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine and Academic Affairs, National Jewish Health, Denver, CO, United States; Department of Medicine, Denver Veterans Affairs Medical Center, Denver, CO, United States; Division of Pulmonary Sciences and Critical Care Medicine, United States. Electronic address: ChanE@NJHealth.org","institution_ids":["https://openalex.org/I3019586173","https://openalex.org/I4210101549"]},{"raw_affiliation_string":"Department of Medicine, Denver Veterans Affairs Medical Center, Denver, CO, United States","institution_ids":["https://openalex.org/I4210101549"]},{"raw_affiliation_string":"Division of Pulmonary Sciences and Critical Care Medicine, United States","institution_ids":[]},{"raw_affiliation_string":"Medicine and Academic Affairs, National Jewish Health, Denver, CO, United States","institution_ids":["https://openalex.org/I3019586173"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5044041242"],"corresponding_institution_ids":["https://openalex.org/I3019586173","https://openalex.org/I4210101549"],"apc_list":{"value":4410,"currency":"USD","value_usd":4410},"apc_paid":null,"fwci":0.7116,"has_fulltext":false,"cited_by_count":50,"citation_normalized_percentile":{"value":0.59322409,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"54","issue":null,"first_page":"66","last_page":"73"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12317","display_name":"Actinomycetales infections and treatment","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nontuberculous-mycobacteria","display_name":"nontuberculous mycobacteria","score":0.9959999918937683},{"id":"https://openalex.org/keywords/pulmonary-ntm-disease","display_name":"pulmonary NTM infection","score":0.8240000009536743},{"id":"https://openalex.org/keywords/host-susceptibility","display_name":"host susceptibility","score":0.6069999933242798},{"id":"https://openalex.org/keywords/genetic-risk-factors","display_name":"genetic risk factors","score":0.847000002861023},{"id":"https://openalex.org/keywords/acquired-risk-factors","display_name":"acquired risk factors","score":0.8100000023841858},{"id":"https://openalex.org/keywords/immunodeficiency","display_name":"immunodeficiency","score":0.8450000286102295},{"id":"https://openalex.org/keywords/host-immune-response","display_name":"host immune response","score":0.7900000214576721},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.6230000257492065}],"concepts":[{"id":"https://openalex.org/C2778679867","wikidata":"https://www.wikidata.org/wiki/Q1881705","display_name":"Nontuberculous mycobacteria","level":4,"score":0.775743842124939},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6842156052589417},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6016803979873657},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5743346214294434},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5631086230278015},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.45143136382102966},{"id":"https://openalex.org/C67636389","wikidata":"https://www.wikidata.org/wiki/Q784237","display_name":"Genetic predisposition","level":3,"score":0.4399430751800537},{"id":"https://openalex.org/C2780374374","wikidata":"https://www.wikidata.org/wiki/Q194309","display_name":"Mycobacterium","level":3,"score":0.2920644283294678},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2751384973526001},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.23666813969612122},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2136731743812561},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12776610255241394},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.07502296566963196}],"mesh":[{"descriptor_ui":"D004198","descriptor_name":"Disease Susceptibility","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009165","descriptor_name":"Mycobacterium Infections, Nontuberculous","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009165","descriptor_name":"Mycobacterium Infections, Nontuberculous","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009170","descriptor_name":"Nontuberculous Mycobacteria","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D037521","descriptor_name":"Virulence Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D037521","descriptor_name":"Virulence Factors","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.coi.2018.06.001","doi":"https://doi.org/10.1016/j.coi.2018.06.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.coi.2018.06.001","pdf_url":null,"source":{"id":"https://openalex.org/S170047187","display_name":"Current Opinion in Immunology","issn_l":"0952-7915","issn":["0952-7915","1879-0372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Immunology","raw_type":"journal-article"},{"id":"pmid:29936307","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29936307","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current opinion in immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8049592898","display_name":"Toxin-induced alternative mRNA splicing in Toll-like receptor signaling pathways","funder_award_id":"R01ES025161","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"}],"funders":[{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":67,"referenced_works":["https://openalex.org/W398006279","https://openalex.org/W1480422785","https://openalex.org/W1494408068","https://openalex.org/W1519385054","https://openalex.org/W1590709474","https://openalex.org/W1792374007","https://openalex.org/W1972570728","https://openalex.org/W1983936403","https://openalex.org/W1985731675","https://openalex.org/W1987217273","https://openalex.org/W1990785540","https://openalex.org/W2006905204","https://openalex.org/W2008072703","https://openalex.org/W2012170616","https://openalex.org/W2013785779","https://openalex.org/W2015641342","https://openalex.org/W2024588790","https://openalex.org/W2026449016","https://openalex.org/W2026708617","https://openalex.org/W2030675030","https://openalex.org/W2031049650","https://openalex.org/W2039927551","https://openalex.org/W2044565392","https://openalex.org/W2047392472","https://openalex.org/W2069433236","https://openalex.org/W2070440819","https://openalex.org/W2073366489","https://openalex.org/W2073790056","https://openalex.org/W2078178166","https://openalex.org/W2078987831","https://openalex.org/W2087955841","https://openalex.org/W2092501038","https://openalex.org/W2093709579","https://openalex.org/W2099430328","https://openalex.org/W2108459792","https://openalex.org/W2112628232","https://openalex.org/W2116780041","https://openalex.org/W2118071000","https://openalex.org/W2119415691","https://openalex.org/W2119462342","https://openalex.org/W2123431872","https://openalex.org/W2125078612","https://openalex.org/W2128719595","https://openalex.org/W2133274440","https://openalex.org/W2151082827","https://openalex.org/W2151977528","https://openalex.org/W2152238466","https://openalex.org/W2154301679","https://openalex.org/W2159507770","https://openalex.org/W2164561211","https://openalex.org/W2166118611","https://openalex.org/W2166606605","https://openalex.org/W2167292122","https://openalex.org/W2171806341","https://openalex.org/W2185955981","https://openalex.org/W2193354899","https://openalex.org/W2206441367","https://openalex.org/W2344425748","https://openalex.org/W2518956672","https://openalex.org/W2564218446","https://openalex.org/W2754135229","https://openalex.org/W2755101109","https://openalex.org/W2772935677","https://openalex.org/W2793198934","https://openalex.org/W2894954589","https://openalex.org/W4247683482","https://openalex.org/W6807901761"],"related_works":["https://openalex.org/W2894954589","https://openalex.org/W3028008321","https://openalex.org/W2804602234","https://openalex.org/W3152898829","https://openalex.org/W4389504966","https://openalex.org/W2311702156","https://openalex.org/W2152238466","https://openalex.org/W1986780814","https://openalex.org/W4408683576","https://openalex.org/W4386027484"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-06-29T00:00:00"}
