{"id":"https://openalex.org/W2809370964","doi":"https://doi.org/10.15171/mejdd.2018.96","title":"Correlation between Serum Ferritin Level and Histopathological Disease Severity in Non-alcoholic Fatty Liver Disease","display_name":"Correlation between Serum Ferritin Level and Histopathological Disease Severity in Non-alcoholic Fatty Liver Disease","publication_year":2018,"publication_date":"2018-03-12","ids":{"openalex":"https://openalex.org/W2809370964","doi":"https://doi.org/10.15171/mejdd.2018.96","mag":"2809370964","pmid":"https://pubmed.ncbi.nlm.nih.gov/30013757","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6040928"},"language":"en","primary_location":{"id":"doi:10.15171/mejdd.2018.96","doi":"https://doi.org/10.15171/mejdd.2018.96","is_oa":true,"landing_page_url":"https://doi.org/10.15171/mejdd.2018.96","pdf_url":"http://mejdd.org/index.php/mejdd/article/download/1986/2061","source":{"id":"https://openalex.org/S2764348800","display_name":"Middle East Journal of Digestive Diseases","issn_l":"2008-5230","issn":["2008-5230","2008-5249","2008-8205"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319077","host_organization_name":"Shiraz University of Medical Sciences","host_organization_lineage":["https://openalex.org/P4310319077"],"host_organization_lineage_names":["Shiraz University of Medical Sciences"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Middle East Journal of Digestive Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://mejdd.org/index.php/mejdd/article/download/1986/2061","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Seyed Reza Modares Mousavi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I119939603","display_name":"Ahvaz Jundishapur University of Medical Sciences","ror":"https://ror.org/01rws6r75","country_code":"IR","type":"education","lineage":["https://openalex.org/I119939603"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Seyed Reza Modares Mousavi","raw_affiliation_strings":["Division of Gastroenterology, Department of Internal Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahwaz, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Department of Internal Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahwaz, Iran","institution_ids":["https://openalex.org/I119939603"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053554120","display_name":"Bita Geramizadeh","orcid":"https://orcid.org/0000-0002-4867-5686","observed_orcids":["https://orcid.org/0000-0002-4867-5686","https://orcid.org/0000-0003-1009-0049"]},"institutions":[{"id":"https://openalex.org/I194604659","display_name":"Shiraz University of Medical Sciences","ror":"https://ror.org/01n3s4692","country_code":"IR","type":"education","lineage":["https://openalex.org/I194604659"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Bita Geramizadeh","raw_affiliation_strings":["Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran","institution_ids":["https://openalex.org/I194604659"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024561441","display_name":"Amir Anushiravani","orcid":"https://orcid.org/0000-0002-9196-1901","observed_orcids":["https://orcid.org/0000-0002-9196-1901"]},"institutions":[{"id":"https://openalex.org/I4403928394","display_name":"Digestive Disease Research Institute","ror":"https://ror.org/04pgf7495","country_code":"IR","type":"facility","lineage":["https://openalex.org/I4403928394","https://openalex.org/I70640408"]},{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Amir Anushiravani","raw_affiliation_strings":["Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I4403928394","https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016712562","display_name":"Fardad Ejtehadi","orcid":"https://orcid.org/0000-0002-0791-0133","observed_orcids":["https://orcid.org/0000-0002-0791-0133"]},"institutions":[{"id":"https://openalex.org/I194604659","display_name":"Shiraz University of Medical Sciences","ror":"https://ror.org/01n3s4692","country_code":"IR","type":"education","lineage":["https://openalex.org/I194604659"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Fardad Ejtehadi","raw_affiliation_strings":["Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran","institution_ids":["https://openalex.org/I194604659"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069232073","display_name":"Mohammad Hossein Anbardar","orcid":"https://orcid.org/0000-0002-2317-0737","observed_orcids":["https://orcid.org/0000-0002-2317-0737"]},"institutions":[{"id":"https://openalex.org/I166459259","display_name":"Shiraz University","ror":"https://ror.org/028qtbk54","country_code":"IR","type":"education","lineage":["https://openalex.org/I166459259"]},{"id":"https://openalex.org/I194604659","display_name":"Shiraz University of Medical Sciences","ror":"https://ror.org/01n3s4692","country_code":"IR","type":"education","lineage":["https://openalex.org/I194604659"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mohammad Hossein Anbardar","raw_affiliation_strings":["Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran","institution_ids":["https://openalex.org/I166459259","https://openalex.org/I194604659"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015280297","display_name":"Maryam Moini","orcid":"https://orcid.org/0000-0001-9619-4206","observed_orcids":["https://orcid.org/0000-0001-9619-4206"]},"institutions":[{"id":"https://openalex.org/I194604659","display_name":"Shiraz University of Medical Sciences","ror":"https://ror.org/01n3s4692","country_code":"IR","type":"education","lineage":["https://openalex.org/I194604659"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Maryam Moini","raw_affiliation_strings":["Non-communicable Disease Research Center, Shiraz University of Medical Sciences, Shiraz, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Non-communicable Disease Research Center, Shiraz University of Medical Sciences, Shiraz, Iran","institution_ids":["https://openalex.org/I194604659"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5015280297"],"corresponding_institution_ids":["https://openalex.org/I194604659"],"apc_list":null,"apc_paid":null,"fwci":1.2802,"has_fulltext":true,"cited_by_count":28,"citation_normalized_percentile":{"value":0.79165998,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"10","issue":"2","first_page":"90","last_page":"95"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-alcoholic-fatty-liver-disease","display_name":"non-alcoholic fatty liver disease","score":0.9279999732971191},{"id":"https://openalex.org/keywords/non-alcoholic-steatohepatitis","display_name":"nonalcoholic steatohepatitis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/serum-ferritin","display_name":"serum ferritin","score":1.0},{"id":"https://openalex.org/keywords/disease-severity","display_name":"disease severity","score":0.7059999704360962},{"id":"https://openalex.org/keywords/fibrosis-stage","display_name":"fibrosis stage","score":0.6980000138282776},{"id":"https://openalex.org/keywords/steatosis-grade","display_name":"steatosis grade","score":0.9670000076293945},{"id":"https://openalex.org/keywords/transferrin-saturation","display_name":"transferrin saturation","score":0.9900000095367432},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.699999988079071},{"id":"https://openalex.org/keywords/young-patients","display_name":"young patients","score":0.628000020980835},{"id":"https://openalex.org/keywords/non-obese-patients","display_name":"non-obese patients","score":0.7929999828338623}],"concepts":[{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.7684441804885864},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.673607349395752},{"id":"https://openalex.org/C2777575235","wikidata":"https://www.wikidata.org/wiki/Q558404","display_name":"Alcoholic liver disease","level":3,"score":0.6615099906921387},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5425440073013306},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.4947476089000702},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4748932421207428},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4702778160572052},{"id":"https://openalex.org/C2778319317","wikidata":"https://www.wikidata.org/wiki/Q22327449","display_name":"Ferritin","level":2,"score":0.4567583203315735},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.42407238483428955},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.32196009159088135},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.12079042196273804},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.15171/mejdd.2018.96","doi":"https://doi.org/10.15171/mejdd.2018.96","is_oa":true,"landing_page_url":"https://doi.org/10.15171/mejdd.2018.96","pdf_url":"http://mejdd.org/index.php/mejdd/article/download/1986/2061","source":{"id":"https://openalex.org/S2764348800","display_name":"Middle East Journal of Digestive Diseases","issn_l":"2008-5230","issn":["2008-5230","2008-5249","2008-8205"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319077","host_organization_name":"Shiraz University of Medical Sciences","host_organization_lineage":["https://openalex.org/P4310319077"],"host_organization_lineage_names":["Shiraz University of Medical Sciences"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Middle East Journal of Digestive Diseases","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4999658","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6040928","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:30013757","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30013757","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Middle East journal of digestive diseases","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6040928","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6040928/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Middle East J Dig Dis","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:b0249faaac9b41e4afeb0bcd86db28b7","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b0249faaac9b41e4afeb0bcd86db28b7","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Middle East Journal of Digestive Diseases, Vol 10, Iss 2, Pp 90-95 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.15171/mejdd.2018.96","doi":"https://doi.org/10.15171/mejdd.2018.96","is_oa":true,"landing_page_url":"https://doi.org/10.15171/mejdd.2018.96","pdf_url":"http://mejdd.org/index.php/mejdd/article/download/1986/2061","source":{"id":"https://openalex.org/S2764348800","display_name":"Middle East Journal of Digestive Diseases","issn_l":"2008-5230","issn":["2008-5230","2008-5249","2008-8205"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319077","host_organization_name":"Shiraz University of Medical Sciences","host_organization_lineage":["https://openalex.org/P4310319077"],"host_organization_lineage_names":["Shiraz University of Medical Sciences"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Middle East Journal of Digestive Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2809370964.pdf","grobid_xml":"https://content.openalex.org/works/W2809370964.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1756401131","https://openalex.org/W1977533715","https://openalex.org/W1980992924","https://openalex.org/W1984365594","https://openalex.org/W1995239046","https://openalex.org/W2047188650","https://openalex.org/W2048613643","https://openalex.org/W2059226395","https://openalex.org/W2060847352","https://openalex.org/W2078009343","https://openalex.org/W2087829753","https://openalex.org/W2095075233","https://openalex.org/W2099184552","https://openalex.org/W2114707445","https://openalex.org/W2116488121","https://openalex.org/W2136861492","https://openalex.org/W2156679550","https://openalex.org/W2162382402","https://openalex.org/W2172266424","https://openalex.org/W2337080773","https://openalex.org/W2529961457","https://openalex.org/W2561821793","https://openalex.org/W2726854871","https://openalex.org/W2897760967"],"related_works":["https://openalex.org/W4240944636","https://openalex.org/W7214519126","https://openalex.org/W7160549509","https://openalex.org/W2095075233","https://openalex.org/W2109452364","https://openalex.org/W7161566403","https://openalex.org/W4315472593","https://openalex.org/W2156679550","https://openalex.org/W172225683","https://openalex.org/W4289517317"],"abstract_inverted_index":{"BACKGROUND":[0],"Non-alcoholic":[1],"fatty":[2],"liver":[3,15],"disease":[4,16,57,195],"(NAFLD)":[5],"is":[6],"one":[7],"of":[8,13,33,44,55,66,85,102,108,122,148,167,191,194],"the":[9,31,42,53,63,119,125,146,189],"most":[10],"common":[11],"causes":[12],"chronic":[14],"worldwide.":[17],"Recently":[18],"several":[19],"parameters,":[20],"such":[21],"as":[22,27,48,184],"serum":[23,45],"ferritin,":[24],"have":[25,141],"emerged":[26],"possible":[28],"predictors":[29],"for":[30,52,188],"severity":[32,58,193],"NAFLD":[34],"and":[35,82,105,165,172],"insulin":[36],"sensitivity.":[37],"We":[38],"aimed":[39],"to":[40],"investigate":[41],"value":[43],"ferritin":[46,127,137,178],"level":[47,138,179],"a":[49,71,115,142,185],"useful":[50,183],"biomarker":[51],"prediction":[54,190],"histopathological":[56,192],"in":[59,76,124,162,196],"non-alcoholic":[60],"steatohepatitis":[61],"(NASH),":[62],"necro-inflammatory":[64],"form":[65],"NAFLD.":[67],"METHODS":[68],"This":[69],"was":[70,133],"prospective":[72],"cross":[73],"sectional":[74],"study":[75],"which":[77],"demographic,":[78],"clinical,":[79],"histological,":[80],"laboratory,":[81],"anthropometric":[83],"data":[84],"30":[86],"adult":[87],"patients":[88,97,198],"with":[89,99,145,199],"biopsy-proven":[90],"NAFLD/NASH":[91],"were":[92],"analyzed.":[93],"RESULTS":[94],"In":[95],"our":[96],"population":[98],"mean":[100,106,126,154],"age":[101],"37.9":[103],"years":[104],"BMI":[107],"26.5,":[109],"statistical":[110],"analysis":[111],"did":[112,139,157],"not":[113,140,158,181,203],"show":[114,159],"significant":[116,143,160],"difference":[117,161],"between":[118],"three":[120],"grades":[121,166],"steatosis":[123],"levels":[128],"(":[129,150,169],"p":[130,151,170],"=0.559).":[131],"It":[132],"also":[134],"observed":[135],"that":[136],"correlation":[144],"stage":[147],"fibrosis":[149],"=0.228).":[152],"The":[153],"transferrin":[155],"saturation":[156],"different":[163],"stages":[164],"NASH":[168,200],"=0.260":[171],"0.944,":[173],"respectively),":[174],"either.":[175],"CONCLUSION":[176],"Serum":[177],"may":[180],"be":[182],"single":[186],"marker":[187],"young":[197],"who":[201],"are":[202],"morbidly":[204],"obese.":[205]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-06-29T00:00:00"}