{"id":"https://openalex.org/W2809268564","doi":"https://doi.org/10.1172/jci.insight.120121","title":"\u03b3\u03b4 T cells: an immunotherapeutic approach for HIV cure strategies","display_name":"\u03b3\u03b4 T cells: an immunotherapeutic approach for HIV cure strategies","publication_year":2018,"publication_date":"2018-06-20","ids":{"openalex":"https://openalex.org/W2809268564","doi":"https://doi.org/10.1172/jci.insight.120121","mag":"2809268564","pmid":"https://pubmed.ncbi.nlm.nih.gov/29925697","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6124426"},"language":"en","primary_location":{"id":"doi:10.1172/jci.insight.120121","doi":"https://doi.org/10.1172/jci.insight.120121","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci.insight.120121","pdf_url":"http://insight.jci.org/articles/view/120121/files/pdf","source":{"id":"https://openalex.org/S2764964142","display_name":"JCI Insight","issn_l":"2379-3708","issn":["2379-3708"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCI Insight","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://insight.jci.org/articles/view/120121/files/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007206510","display_name":"Carolina Garrido","orcid":"https://orcid.org/0000-0001-7697-6876","observed_orcids":["https://orcid.org/0000-0001-7697-6876"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carolina Garrido","raw_affiliation_strings":["Departments of Medicine,","UNC-HIV Cure Center,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine,","institution_ids":[]},{"raw_affiliation_string":"UNC-HIV Cure Center,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073909182","display_name":"Matthew L. Clohosey","orcid":"https://orcid.org/0000-0002-5986-057X","observed_orcids":["https://orcid.org/0000-0002-5986-057X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matthew L. Clohosey","raw_affiliation_strings":["Departments of Medicine,","UNC-HIV Cure Center,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine,","institution_ids":[]},{"raw_affiliation_string":"UNC-HIV Cure Center,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072231556","display_name":"Chloe P. Whitworth","orcid":"https://orcid.org/0000-0001-5726-6158","observed_orcids":["https://orcid.org/0000-0001-5726-6158"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chloe P. Whitworth","raw_affiliation_strings":["Departments of Medicine,","UNC-HIV Cure Center,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine,","institution_ids":[]},{"raw_affiliation_string":"UNC-HIV Cure Center,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078111251","display_name":"Michael G. Hudgens","orcid":"https://orcid.org/0000-0002-9106-4194","observed_orcids":["https://orcid.org/0000-0002-9106-4194"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Hudgens","raw_affiliation_strings":["Biostatistics,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biostatistics,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008716404","display_name":"David M. Margolis","orcid":"https://orcid.org/0000-0001-5714-0002","observed_orcids":["https://orcid.org/0000-0001-5714-0002"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David M. Margolis","raw_affiliation_strings":["Departments of Medicine,","Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA","Microbiology and Immunology, and","UNC-HIV Cure Center,"],"raw_orcid":"https://orcid.org/0000-0001-5714-0002","affiliations":[{"raw_affiliation_string":"Departments of Medicine,","institution_ids":[]},{"raw_affiliation_string":"Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Microbiology and Immunology, and","institution_ids":[]},{"raw_affiliation_string":"UNC-HIV Cure Center,","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022278573","display_name":"Natalia Soriano-Sarabia","orcid":"https://orcid.org/0000-0002-2349-263X","observed_orcids":["https://orcid.org/0000-0002-2349-263X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Natalia Soriano-Sarabia","raw_affiliation_strings":["Departments of Medicine,","UNC-HIV Cure Center,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine,","institution_ids":[]},{"raw_affiliation_string":"UNC-HIV Cure Center,","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5022278573"],"corresponding_institution_ids":[],"apc_list":{"value":4100,"currency":"USD","value_usd":4100},"apc_paid":{"value":4100,"currency":"USD","value_usd":4100},"fwci":1.7021,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.82527257,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"3","issue":"12","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gamma-delta-t-cells","display_name":"\u03b3\u03b4 T cells","score":0.9819999933242798},{"id":"https://openalex.org/keywords/hiv-cure","display_name":"HIV cure","score":0.9890000224113464},{"id":"https://openalex.org/keywords/hiv-latency","display_name":"HIV latency","score":0.5740000009536743},{"id":"https://openalex.org/keywords/viral-reservoir","display_name":"viral reservoir","score":0.6570000052452087},{"id":"https://openalex.org/keywords/latency-reversal","display_name":"latency reversal","score":0.8629999756813049},{"id":"https://openalex.org/keywords/vorinostat","display_name":"vorinostat","score":0.9869999885559082},{"id":"https://openalex.org/keywords/pamidronate","display_name":"pamidronate","score":0.9819999933242798},{"id":"https://openalex.org/keywords/ex-vivo-t-cell-expansion","display_name":"ex vivo T cell expansion","score":0.7329999804496765},{"id":"https://openalex.org/keywords/hiv-replication-inhibition","display_name":"HIV replication inhibition","score":0.609000027179718},{"id":"https://openalex.org/keywords/cd4-t-cell-infection","display_name":"CD4+ T cell infection","score":0.6520000100135803},{"id":"https://openalex.org/keywords/hiv-eradication","display_name":"HIV eradication","score":0.6629999876022339}],"concepts":[{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.744685173034668},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5334966778755188},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.5069818496704102},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4867139160633087},{"id":"https://openalex.org/C67662055","wikidata":"https://www.wikidata.org/wiki/Q1047791","display_name":"Antigen-presenting cell","level":4,"score":0.46366646885871887},{"id":"https://openalex.org/C26291073","wikidata":"https://www.wikidata.org/wiki/Q310484","display_name":"Ex vivo","level":3,"score":0.4613191783428192},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.4443071782588959},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.43331652879714966},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40684860944747925},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3958824872970581},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3875461518764496},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.27083417773246765},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.1795884370803833},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015488","descriptor_name":"HIV Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015496","descriptor_name":"CD4-Positive T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016692","descriptor_name":"Receptors, Antigen, T-Cell, gamma-delta","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D018414","descriptor_name":"CD8-Positive T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1172/jci.insight.120121","doi":"https://doi.org/10.1172/jci.insight.120121","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci.insight.120121","pdf_url":"http://insight.jci.org/articles/view/120121/files/pdf","source":{"id":"https://openalex.org/S2764964142","display_name":"JCI Insight","issn_l":"2379-3708","issn":["2379-3708"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCI Insight","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5079454","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6124426","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6124426","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6124426","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCI Insight","raw_type":"Text"},{"id":"pmid:29925697","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29925697","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCI insight","raw_type":"Journal Article"},{"id":"pmh:cdr.lib.unc.edu:8623j392d","doi":null,"is_oa":false,"landing_page_url":"https://doi.org/10.17615/apmv-mc41","pdf_url":null,"source":{"id":"https://openalex.org/S4306401075","display_name":"Carolina Digital Repository (University of North Carolina at Chapel Hill)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114027177","host_organization_name":"University of North Carolina at Chapel Hill","host_organization_lineage":["https://openalex.org/I114027177"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"JCI insight, 3(12)","raw_type":"Article"},{"id":"doi:10.17615/apmv-mc41","doi":"https://doi.org/10.17615/apmv-mc41","is_oa":true,"landing_page_url":"https://doi.org/10.17615/apmv-mc41","pdf_url":null,"source":{"id":"https://openalex.org/S7407051488","display_name":"UNC Libraries","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1172/jci.insight.120121","doi":"https://doi.org/10.1172/jci.insight.120121","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci.insight.120121","pdf_url":"http://insight.jci.org/articles/view/120121/files/pdf","source":{"id":"https://openalex.org/S2764964142","display_name":"JCI Insight","issn_l":"2379-3708","issn":["2379-3708"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCI Insight","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8199999928474426}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3234845076","display_name":"Collaboratory of AIDS Researchers for Eradication (CARE)","funder_award_id":"UM1AI126619","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G3346135917","display_name":null,"funder_award_id":"AI12509-01A1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5106888154","display_name":"Peripheral and tissue-resident gamm/delta T cells in HIV latency","funder_award_id":"R01AI125097","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5520316217","display_name":null,"funder_award_id":"NIH-R01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000894295","display_name":"The University of North Carolina Center for AIDS Research","funder_award_id":"P30AI050410","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000913976","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA016086","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2809268564.pdf","grobid_xml":"https://content.openalex.org/works/W2809268564.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W153696494","https://openalex.org/W1497870368","https://openalex.org/W1500217023","https://openalex.org/W1535243328","https://openalex.org/W1540974329","https://openalex.org/W1601232563","https://openalex.org/W1978436252","https://openalex.org/W1982881862","https://openalex.org/W1986805261","https://openalex.org/W1997719382","https://openalex.org/W2002820975","https://openalex.org/W2018540827","https://openalex.org/W2025813228","https://openalex.org/W2025885829","https://openalex.org/W2030844138","https://openalex.org/W2048072477","https://openalex.org/W2051015958","https://openalex.org/W2058222130","https://openalex.org/W2068937296","https://openalex.org/W2075106941","https://openalex.org/W2075429912","https://openalex.org/W2077634460","https://openalex.org/W2081648804","https://openalex.org/W2085384576","https://openalex.org/W2090646713","https://openalex.org/W2092524383","https://openalex.org/W2100915708","https://openalex.org/W2108793355","https://openalex.org/W2111836805","https://openalex.org/W2112660458","https://openalex.org/W2116180395","https://openalex.org/W2122695363","https://openalex.org/W2126044591","https://openalex.org/W2127367385","https://openalex.org/W2145025818","https://openalex.org/W2150390398","https://openalex.org/W2150709239","https://openalex.org/W2154705046","https://openalex.org/W2164267446","https://openalex.org/W2178101041","https://openalex.org/W2183777144","https://openalex.org/W2232375730","https://openalex.org/W2262809677","https://openalex.org/W2489079158","https://openalex.org/W2512878063","https://openalex.org/W2546649885","https://openalex.org/W2558711397","https://openalex.org/W2754430747","https://openalex.org/W2794490228"],"related_works":["https://openalex.org/W3024211359","https://openalex.org/W7128473665","https://openalex.org/W3026879848","https://openalex.org/W2328743753","https://openalex.org/W2077634460","https://openalex.org/W4416895313","https://openalex.org/W7097307121","https://openalex.org/W986489368","https://openalex.org/W2990477127","https://openalex.org/W2232375730"],"abstract_inverted_index":{"Current":[0],"strategies":[1,29],"aimed":[2],"to":[3,12,24,42,70,131,168],"cure":[4,97],"HIV":[5,44,96,134,180,203],"infection":[6],"are":[7,30,39,126],"based":[8],"on":[9,33],"combined":[10],"efforts":[11],"reactivate":[13],"the":[14,141,163,192],"virus":[15],"from":[16,47,102],"latency":[17,157,183],"and":[18,37,50,72,113,149,177],"improve":[19],"immune":[20],"effector":[21,64],"cell":[22],"function":[23],"clear":[25,152,178],"infected":[26,48,78,145,154],"cells.":[27,55],"These":[28,123],"primarily":[31],"focused":[32],"CD8+":[34,53],"T":[35,54,57,65,88,100,147,174,197],"cells":[36,49,58,66,79,89,101,114,124,155,175,198],"approaches":[38],"challenging":[40],"due":[41],"insufficient":[43],"antigen":[45],"production":[46],"poor":[51],"HIV-specific":[52],"\u03b3\u03b4":[56,87,99,173,196],"represent":[59,90],"a":[60,91],"unique":[61],"subset":[62],"of":[63,143,166,195],"that":[67,172],"can":[68],"traffic":[69],"tissues,":[71],"selectively":[73],"target":[74,176],"cancer":[75],"or":[76],"virally":[77],"without":[80],"requiring":[81],"MHC":[82],"presentation.":[83],"We":[84],"analyzed":[85],"whether":[86],"complementary/alternative":[92],"immunotherapeutic":[93,193],"approach":[94],"towards":[95],"strategies.":[98,205],"HIV-infected":[103],"virologically":[104],"suppressed":[105],"donors":[106],"were":[107,115],"expanded":[108],"with":[109,159],"bisphosphonate":[110],"pamidronate":[111],"(PAM)":[112],"used":[116],"in":[117,140,202],"autologous":[118,144,179],"cellular":[119],"systems":[120],"ex":[121,136],"vivo.":[122],"(a)":[125],"potent":[127],"cytotoxic":[128],"effectors":[129],"able":[130],"efficiently":[132],"inhibit":[133],"replication":[135],"vivo,":[137],"(b)":[138],"degranulate":[139],"presence":[142],"CD4+":[146],"cells,":[148],"(c)":[150],"specifically":[151],"latently":[153],"after":[156],"reversal":[158],"vorinostat.":[160],"This":[161],"is":[162],"first":[164],"proof":[165],"concept":[167],"our":[169],"knowledge":[170],"showing":[171],"reservoirs":[181],"upon":[182],"reversal.":[184],"Our":[185],"results":[186],"open":[187],"potentially":[188],"new":[189],"insights":[190],"into":[191],"use":[194],"for":[199],"current":[200],"interventions":[201],"eradication":[204]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":6}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-06-29T00:00:00"}