{"id":"https://openalex.org/W2809057232","doi":"https://doi.org/10.1093/annonc/mdy151.274","title":"Selective internal radiation therapy (SIRT) with yttrium-90 microspheres and peri-procedural FOLFIRI/irinotecan in pre-treated colorectal liver metastases patients: An analysis of outcomes from a UK Cancer Centre between 2009 and 2017","display_name":"Selective internal radiation therapy (SIRT) with yttrium-90 microspheres and peri-procedural FOLFIRI/irinotecan in pre-treated colorectal liver metastases patients: An analysis of outcomes from a UK Cancer Centre between 2009 and 2017","publication_year":2018,"publication_date":"2018-06-01","ids":{"openalex":"https://openalex.org/W2809057232","doi":"https://doi.org/10.1093/annonc/mdy151.274","mag":"2809057232"},"language":"en","primary_location":{"id":"doi:10.1093/annonc/mdy151.274","doi":"https://doi.org/10.1093/annonc/mdy151.274","is_oa":true,"landing_page_url":"https://doi.org/10.1093/annonc/mdy151.274","pdf_url":null,"source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1093/annonc/mdy151.274","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050694817","display_name":"G. Wilson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"G. Wilson","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":null,"display_name":"D. Bentley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D. Bentley","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086373936","display_name":"Saifee Mullamitha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131968","display_name":"The Christie Hospital","ror":"https://ror.org/03nd63441","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210131968","https://openalex.org/I4210133995"]},{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S. Mullamitha","raw_affiliation_strings":["The Christie Hospital NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie Hospital NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210131968","https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054515664","display_name":"Mike Braun","orcid":"https://orcid.org/0000-0002-6666-4868","observed_orcids":["https://orcid.org/0000-0002-6666-4868"]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M. Braun","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113710549","display_name":"Magdy Nasralla","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M. Nasralla","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000126471","display_name":"Jon K. Bell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. Bell","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046470248","display_name":"Damian Mullan","orcid":"https://orcid.org/0000-0002-9399-6622","observed_orcids":["https://orcid.org/0000-0002-9399-6622"]},"institutions":[{"id":"https://openalex.org/I4210131968","display_name":"The Christie Hospital","ror":"https://ror.org/03nd63441","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210131968","https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D. Mullan","raw_affiliation_strings":["The Christie Hospital, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie Hospital, Manchester, UK","institution_ids":["https://openalex.org/I4210131968"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020983677","display_name":"Jurjees Hasan","orcid":"https://orcid.org/0000-0002-1956-8929","observed_orcids":["https://orcid.org/0000-0002-1956-8929"]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. Hasan","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040081800","display_name":"Mark P. Saunders","orcid":"https://orcid.org/0000-0002-7195-4712","observed_orcids":["https://orcid.org/0000-0002-7195-4712"]},"institutions":[{"id":"https://openalex.org/I4210131968","display_name":"The Christie Hospital","ror":"https://ror.org/03nd63441","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210131968","https://openalex.org/I4210133995"]},{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M. Saunders","raw_affiliation_strings":["Christie Hospital NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Christie Hospital NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210131968","https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056023267","display_name":"Francisca M. Marti","orcid":"https://orcid.org/0000-0003-2647-5349","observed_orcids":["https://orcid.org/0000-0003-2647-5349"]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"F. Marti","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":null,"display_name":"C. McBain","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"C. McBain","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021867313","display_name":"N. Alam","orcid":"https://orcid.org/0000-0001-9542-3054","observed_orcids":["https://orcid.org/0000-0001-9542-3054"]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"N. Alam","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045783671","display_name":"Hans\u2010Ulrich Laasch","orcid":"https://orcid.org/0000-0003-3109-6933","observed_orcids":["https://orcid.org/0000-0003-3109-6933"]},"institutions":[{"id":"https://openalex.org/I4210131968","display_name":"The Christie Hospital","ror":"https://ror.org/03nd63441","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210131968","https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"H. Laasch","raw_affiliation_strings":["The Christie Hospital, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie Hospital, Manchester, UK","institution_ids":["https://openalex.org/I4210131968"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087127593","display_name":"Pavan Singh Najran","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P. Najran","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068255857","display_name":"Thomas Westwood","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"T. Westwood","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113641115","display_name":"Stephen P. Jeans","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S. Jeans","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010566883","display_name":"Jill Tipping","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. Tipping","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107880619","display_name":"Prakash Manoharan","orcid":"https://orcid.org/0000-0002-5155-2310","observed_orcids":["https://orcid.org/0000-0002-5155-2310"]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P. Manoharan","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048587251","display_name":"Jeremy Lawrance","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. Lawrance","raw_affiliation_strings":["The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5080,"currency":"USD","value_usd":5080},"apc_paid":{"value":5080,"currency":"USD","value_usd":5080},"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.07628537,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"29","issue":null,"first_page":"v78","last_page":"v78"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.9286999702453613,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.9286999702453613,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.055799998342990875,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radioembolization","display_name":"radioembolization","score":0.9980000257492065},{"id":"https://openalex.org/keywords/yttrium-90-microspheres","display_name":"yttrium-90 microspheres","score":0.9980000257492065},{"id":"https://openalex.org/keywords/colorectal-liver-metastases","display_name":"colorectal liver metastases","score":0.9390000104904175},{"id":"https://openalex.org/keywords/folfiri","display_name":"FOLFIRI","score":0.8790000081062317},{"id":"https://openalex.org/keywords/irinotecan","display_name":"irinotecan","score":0.9929999709129333},{"id":"https://openalex.org/keywords/radiosensitization","display_name":"radiosensitization","score":0.9380000233650208},{"id":"https://openalex.org/keywords/treatment-outcomes","display_name":"treatment outcomes","score":0.527999997138977}],"concepts":[{"id":"https://openalex.org/C2776705615","wikidata":"https://www.wikidata.org/wiki/Q1389369","display_name":"FOLFIRI","level":5,"score":0.954075038433075},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9125062227249146},{"id":"https://openalex.org/C2780259306","wikidata":"https://www.wikidata.org/wiki/Q412197","display_name":"Irinotecan","level":4,"score":0.8611660599708557},{"id":"https://openalex.org/C2780962732","wikidata":"https://www.wikidata.org/wiki/Q422327","display_name":"Oxaliplatin","level":4,"score":0.7052316069602966},{"id":"https://openalex.org/C2777909004","wikidata":"https://www.wikidata.org/wiki/Q420207","display_name":"Capecitabine","level":4,"score":0.6172366738319397},{"id":"https://openalex.org/C2778260052","wikidata":"https://www.wikidata.org/wiki/Q117636","display_name":"FOLFOX","level":5,"score":0.6150049567222595},{"id":"https://openalex.org/C2779998722","wikidata":"https://www.wikidata.org/wiki/Q420296","display_name":"Cetuximab","level":4,"score":0.597015380859375},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5779920816421509},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.5775986909866333},{"id":"https://openalex.org/C2779185275","wikidata":"https://www.wikidata.org/wiki/Q2267963","display_name":"Selective internal radiation therapy","level":3,"score":0.5756527781486511},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4957071542739868},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.46835651993751526},{"id":"https://openalex.org/C2778336483","wikidata":"https://www.wikidata.org/wiki/Q5090632","display_name":"Chemotherapy regimen","level":3,"score":0.43185046315193176},{"id":"https://openalex.org/C2780456651","wikidata":"https://www.wikidata.org/wiki/Q238512","display_name":"Fluorouracil","level":3,"score":0.4304353594779968},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.4239426255226135},{"id":"https://openalex.org/C2777148230","wikidata":"https://www.wikidata.org/wiki/Q17144959","display_name":"FOLFIRINOX","level":5,"score":0.4217655658721924},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3627866506576538},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.35600489377975464},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3121728003025055},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.04917052388191223}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/annonc/mdy151.274","doi":"https://doi.org/10.1093/annonc/mdy151.274","is_oa":true,"landing_page_url":"https://doi.org/10.1093/annonc/mdy151.274","pdf_url":null,"source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1093/annonc/mdy151.274","doi":"https://doi.org/10.1093/annonc/mdy151.274","is_oa":true,"landing_page_url":"https://doi.org/10.1093/annonc/mdy151.274","pdf_url":null,"source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4243039938","https://openalex.org/W2425739424","https://openalex.org/W2791031760","https://openalex.org/W1968690354","https://openalex.org/W2601802226","https://openalex.org/W2323577155","https://openalex.org/W1968358021","https://openalex.org/W1989002398","https://openalex.org/W2501244506","https://openalex.org/W2914937228"],"abstract_inverted_index":{"Introduction:":[0],"Selective":[1],"Internal":[2],"Radiation":[3],"Therapy":[4],"(SIRT)":[5],"involves":[6],"hepatic":[7,24],"intra-arterial":[8],"infusion":[9],"of":[10],"\u03b2-particle":[11],"emitting":[12],"Yttrium-90":[13],"labelled":[14],"microspheres.":[15],"SIRT":[16,42],"increases":[17],"first":[18],"line":[19],"response":[20],"rates":[21],"(RR)":[22],"and":[23,56],"progression":[25],"free":[26],"survival":[27],"(hPFS)":[28],"in":[29,46],"liver":[30],"predominant":[31],"metastatic":[32],"colorectal":[33],"cancer":[34],"(mCRC)":[35],"patients":[36,49],"treated":[37],"with":[38,50],"oxaliplatin/5FU/folinic":[39],"acid":[40],"(FOLFOX).":[41],"is":[43],"often":[44],"used":[45],"pre-treated":[47],"mCRC":[48],"peri-procedural":[51],"FOLFOX":[52],"to":[53],"achieve":[54],"radio-sensitization":[55],"control":[57],"extra-hepatic":[58],"disease.":[59]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2018-06-29T00:00:00"}