{"id":"https://openalex.org/W2808923723","doi":"https://doi.org/10.9734/jamps/2018/41291","title":"Hydroethanolic Extracts of Ficus pumila Linn. Is Protective against Gentamicin-Induced Kidney Damage in Rats","display_name":"Hydroethanolic Extracts of Ficus pumila Linn. Is Protective against Gentamicin-Induced Kidney Damage in Rats","publication_year":2018,"publication_date":"2018-06-15","ids":{"openalex":"https://openalex.org/W2808923723","doi":"https://doi.org/10.9734/jamps/2018/41291","mag":"2808923723"},"language":"en","primary_location":{"id":"doi:10.9734/jamps/2018/41291","doi":"https://doi.org/10.9734/jamps/2018/41291","is_oa":true,"landing_page_url":"https://doi.org/10.9734/jamps/2018/41291","pdf_url":null,"source":{"id":"https://openalex.org/S2764462864","display_name":"Journal of Advances in Medical and Pharmaceutical Sciences","issn_l":"2394-1111","issn":["2394-1111"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320855","host_organization_name":"Sciencedomain International","host_organization_lineage":["https://openalex.org/P4310320855"],"host_organization_lineage_names":["Sciencedomain International"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Advances in Medical and Pharmaceutical Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.9734/jamps/2018/41291","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015992167","display_name":"Christopher Larbie","orcid":"https://orcid.org/0000-0003-4927-4419","observed_orcids":["https://orcid.org/0000-0003-4927-4419"]},"institutions":[{"id":"https://openalex.org/I28046988","display_name":"Kwame Nkrumah University of Science and Technology","ror":"https://ror.org/00cb23x68","country_code":"GH","type":"education","lineage":["https://openalex.org/I28046988"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"Christopher Larbie","raw_affiliation_strings":["Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana","institution_ids":["https://openalex.org/I28046988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5097240757","display_name":"Portia Siaw","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28046988","display_name":"Kwame Nkrumah University of Science and Technology","ror":"https://ror.org/00cb23x68","country_code":"GH","type":"education","lineage":["https://openalex.org/I28046988"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"Portia Siaw","raw_affiliation_strings":["Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana","institution_ids":["https://openalex.org/I28046988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040681954","display_name":"Solomon Zon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28046988","display_name":"Kwame Nkrumah University of Science and Technology","ror":"https://ror.org/00cb23x68","country_code":"GH","type":"education","lineage":["https://openalex.org/I28046988"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"Solomon Zon","raw_affiliation_strings":["Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana","institution_ids":["https://openalex.org/I28046988"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031596883","display_name":"Kwame Appiah-Kubi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28046988","display_name":"Kwame Nkrumah University of Science and Technology","ror":"https://ror.org/00cb23x68","country_code":"GH","type":"education","lineage":["https://openalex.org/I28046988"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"Kwame Appiah-Kubi","raw_affiliation_strings":["Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana","institution_ids":["https://openalex.org/I28046988"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I28046988"],"apc_list":null,"apc_paid":null,"fwci":0.1855,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.46392542,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"17","issue":"2","first_page":"1","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12429","display_name":"Chemotherapy-induced organ toxicity mitigation","score":0.6122999787330627,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12429","display_name":"Chemotherapy-induced organ toxicity mitigation","score":0.6122999787330627,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13422","display_name":"Phytochemistry and biological activities of Ficus species","score":0.3725999891757965,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ficus-pumila","display_name":"Ficus pumila","score":1.0},{"id":"https://openalex.org/keywords/renal-protection","display_name":"renal protection","score":0.8360000252723694},{"id":"https://openalex.org/keywords/gentamicin-induced-nephrotoxicity","display_name":"gentamicin nephrotoxicity","score":0.9779999852180481},{"id":"https://openalex.org/keywords/hydroethanolic-leaf-extract","display_name":"hydroethanolic leaf extract","score":0.9319999814033508},{"id":"https://openalex.org/keywords/plant-extracts","display_name":"plant extracts","score":0.5440000295639038},{"id":"https://openalex.org/keywords/silymarin","display_name":"silymarin","score":0.8230000138282776},{"id":"https://openalex.org/keywords/serum-creatinine","display_name":"serum creatinine","score":0.8479999899864197},{"id":"https://openalex.org/keywords/urea","display_name":"urea","score":0.7710000276565552},{"id":"https://openalex.org/keywords/hematological-parameters","display_name":"hematological parameters","score":0.8259999752044678},{"id":"https://openalex.org/keywords/kidney-injury","display_name":"kidney injury","score":0.3409999907016754}],"concepts":[{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.7465330958366394},{"id":"https://openalex.org/C2775832221","wikidata":"https://www.wikidata.org/wiki/Q422482","display_name":"Gentamicin","level":3,"score":0.7134179472923279},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4492824375629425},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2538599371910095},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.14501479268074036},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.10204273462295532}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.9734/jamps/2018/41291","doi":"https://doi.org/10.9734/jamps/2018/41291","is_oa":true,"landing_page_url":"https://doi.org/10.9734/jamps/2018/41291","pdf_url":null,"source":{"id":"https://openalex.org/S2764462864","display_name":"Journal of Advances in Medical and Pharmaceutical Sciences","issn_l":"2394-1111","issn":["2394-1111"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320855","host_organization_name":"Sciencedomain International","host_organization_lineage":["https://openalex.org/P4310320855"],"host_organization_lineage_names":["Sciencedomain International"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Advances in Medical and Pharmaceutical Sciences","raw_type":"journal-article"},{"id":"pmh:oai:journaljamps.com:article/332","doi":null,"is_oa":true,"landing_page_url":"https://journaljamps.com/index.php/JAMPS/article/view/332","pdf_url":null,"source":{"id":"https://openalex.org/S2764462864","display_name":"Journal of Advances in Medical and Pharmaceutical Sciences","issn_l":"2394-1111","issn":["2394-1111"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320855","host_organization_name":"Sciencedomain International","host_organization_lineage":["https://openalex.org/P4310320855"],"host_organization_lineage_names":["Sciencedomain International"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2394-1111","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:HAL:hal-05362007v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-05362007","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Advances in Medical and Pharmaceutical Sciences, 2018, 17 (2), pp.1-8","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.9734/jamps/2018/41291","doi":"https://doi.org/10.9734/jamps/2018/41291","is_oa":true,"landing_page_url":"https://doi.org/10.9734/jamps/2018/41291","pdf_url":null,"source":{"id":"https://openalex.org/S2764462864","display_name":"Journal of Advances in Medical and Pharmaceutical Sciences","issn_l":"2394-1111","issn":["2394-1111"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320855","host_organization_name":"Sciencedomain International","host_organization_lineage":["https://openalex.org/P4310320855"],"host_organization_lineage_names":["Sciencedomain International"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Advances in Medical and Pharmaceutical Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7217752132","https://openalex.org/W1896905749","https://openalex.org/W2581184242","https://openalex.org/W4388916248","https://openalex.org/W437050768","https://openalex.org/W2886480356","https://openalex.org/W2963947346","https://openalex.org/W2552271197","https://openalex.org/W2686058687","https://openalex.org/W2178372907"],"abstract_inverted_index":{"Ficus":[0,202],"pumila":[1,35,90,203],"Linn.":[2],"has":[3],"been":[4],"reported":[5],"to":[6,24],"be":[7],"rich":[8],"in":[9,40,189,209],"phenols,":[10],"hepatoprotective":[11],"and":[12,88,95,113,119,124,143,145,164,171,182],"antiproliferative":[13],"on":[14,36],"leukemic":[15],"cancer":[16],"cells.":[17],"The":[18,195],"aim":[19],"of":[20,29,33,158,192,201],"this":[21],"study":[22],"was":[23,59,152],"evaluate":[25],"the":[26,60,108,140,183,190],"nephroprotective":[27],"effect":[28],"hydroethanolic":[30],"leaves":[31,204],"extracts":[32],"F.":[34,89],"gentamicin-induced":[37,207],"kidney":[38],"damage":[39],"rats.":[41,213],"Twenty-seven":[42],"female":[43,210],"Wistar":[44,211],"albino":[45,212],"rats":[46,77,106],"were":[47,78,135,148],"divided":[48],"into":[49],"9":[50,121],"groups":[51,72,101],"(n=3).":[52],"Group":[53],"1":[54],"being":[55,122],"normal;":[56],"group":[57,120],"2":[58],"gentamicin":[61,81,123,181],"(GM)":[62],"induced":[63],"only":[64,110],"(80":[65],"mg/kg":[66,97,115,127],"b/w":[67,83,98,116,128],"ip":[68,84],"for":[69,85,130],"5":[70,76,86],"days);":[71],"3,":[73],"4,":[74],"&":[75,104],"treated":[79,179],"with":[80,175,180],"(80mg/kg":[82],"days)":[87],"extract":[91,109,184,200],"at":[92],"100,":[93],"250,":[94,112],"500":[96,114],"orally":[99],"respectively;":[100],"6,":[102],"7":[103],"8":[105],"received":[107],"(100,":[111],"orally)":[117,129],"respectively":[118],"silymarin":[125],"(100":[126],"21":[131],"days.":[132],"Blood":[133],"samples":[134],"taken":[136],"24":[137],"hrs":[138],"after":[139],"experimented":[141],"period":[142],"biochemical":[144],"haematological":[146],"parameters":[147],"analyzed.":[149],"GM":[150],"nephrotoxicity":[151,208],"characterized":[153],"by":[154],"significantly":[155],"increased":[156],"levels":[157,173,191],"serum":[159],"creatinine,":[160],"urea,":[161],"sodium,":[162],"potassium":[163],"WBC,":[165],"while":[166],"reduced":[167],"RBC,":[168],"HGB,":[169],"MCH":[170],"MCV":[172],"compared":[174],"normal":[176],"group.":[177],"Rats":[178],"showed":[185],"a":[186],"significant":[187],"reduction":[188],"these":[193],"markers.":[194],"results":[196],"suggest":[197],"that":[198],"hydro-ethanolic":[199],"protect":[205],"against":[206]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2018-06-29T00:00:00"}
