{"id":"https://openalex.org/W2808917216","doi":"https://doi.org/10.1016/j.jceh.2018.06.007","title":"Hyperammonemia in Hepatic Encephalopathy","display_name":"Hyperammonemia in Hepatic Encephalopathy","publication_year":2018,"publication_date":"2018-06-20","ids":{"openalex":"https://openalex.org/W2808917216","doi":"https://doi.org/10.1016/j.jceh.2018.06.007","mag":"2808917216","pmid":"https://pubmed.ncbi.nlm.nih.gov/30302044","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6175739"},"language":"en","primary_location":{"id":"doi:10.1016/j.jceh.2018.06.007","doi":"https://doi.org/10.1016/j.jceh.2018.06.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jceh.2018.06.007","pdf_url":"http://www.jcehepatology.com/article/S097368831830094X/pdf","source":{"id":"https://openalex.org/S2764866434","display_name":"Journal of Clinical and Experimental Hepatology","issn_l":"0973-6883","issn":["0973-6883","2213-3453"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","ki-jl-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical and Experimental Hepatology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.jcehepatology.com/article/S097368831830094X/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101657013","display_name":"Arumugam Radhakrishnan Jayakumar","orcid":"https://orcid.org/0009-0009-2115-7860","observed_orcids":["https://orcid.org/0009-0009-2115-7860"]},"institutions":[{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]},{"id":"https://openalex.org/I4210145816","display_name":"South Florida Veterans Affairs Foundation for Research and Education","ror":"https://ror.org/04g6ht049","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210145816"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"A.R. Jayakumar","raw_affiliation_strings":["General Medical Research, Neuropathology Section, R&D Service, Veterans Affairs Medical Center, Miami, FL 33125, United States","South Florida VA Foundation for Research and Education Inc., Veterans Affairs Medical Center, Miami, FL 33125, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"General Medical Research, Neuropathology Section, R&D Service, Veterans Affairs Medical Center, Miami, FL 33125, United States","institution_ids":["https://openalex.org/I2799886695"]},{"raw_affiliation_string":"South Florida VA Foundation for Research and Education Inc., Veterans Affairs Medical Center, Miami, FL 33125, United States","institution_ids":["https://openalex.org/I4210145816"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111990004","display_name":"Michael D. Norenberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael D. Norenberg","raw_affiliation_strings":["Department of Biochemistry & Molecular Biology, University of Miami School of Medicine, Miami, FL 33125, United States","Department of Neurology and Neurological Surgery, University of Miami School of Medicine, Miami, FL 33125, United States","Department of Pathology, University of Miami School of Medicine, Miami, FL 33125, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry & Molecular Biology, University of Miami School of Medicine, Miami, FL 33125, United States","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Neurology and Neurological Surgery, University of Miami School of Medicine, Miami, FL 33125, United States","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Pathology, University of Miami School of Medicine, Miami, FL 33125, United States","institution_ids":["https://openalex.org/I145608581"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5101657013","https://openalex.org/A5111990004"],"corresponding_institution_ids":["https://openalex.org/I145608581","https://openalex.org/I2799886695","https://openalex.org/I4210145816"],"apc_list":{"value":3150,"currency":"USD","value_usd":3150},"apc_paid":null,"fwci":0.8881,"has_fulltext":true,"cited_by_count":117,"citation_normalized_percentile":{"value":0.74631061,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"8","issue":"3","first_page":"272","last_page":"280"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13201","display_name":"Infectious Encephalopathies and Encephalitis","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatic-encephalopathy","display_name":"hepatic encephalopathy","score":0.9330000281333923},{"id":"https://openalex.org/keywords/hyperammonemia","display_name":"hyperammonemia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ammonia-neurotoxicity","display_name":"ammonia neurotoxicity","score":0.8679999709129333},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.5519999861717224},{"id":"https://openalex.org/keywords/acute-liver-failure","display_name":"acute liver failure","score":0.7300000190734863},{"id":"https://openalex.org/keywords/chronic-liver-failure","display_name":"chronic liver failure","score":0.9900000095367432},{"id":"https://openalex.org/keywords/astrocytes","display_name":"astrocytes","score":0.7590000033378601},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.8349999785423279},{"id":"https://openalex.org/keywords/neurological-complications","display_name":"neurological complications","score":0.5210000276565552}],"concepts":[{"id":"https://openalex.org/C2781099255","wikidata":"https://www.wikidata.org/wiki/Q1640868","display_name":"Hyperammonemia","level":2,"score":0.9398690462112427},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9084793329238892},{"id":"https://openalex.org/C2780325230","wikidata":"https://www.wikidata.org/wiki/Q642548","display_name":"Hepatic encephalopathy","level":3,"score":0.7405609488487244},{"id":"https://openalex.org/C2778621155","wikidata":"https://www.wikidata.org/wiki/Q576349","display_name":"Encephalopathy","level":2,"score":0.5249229073524475},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4312910735607147},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3383685350418091},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3318184018135071},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3121291697025299},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.10207104682922363}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.jceh.2018.06.007","doi":"https://doi.org/10.1016/j.jceh.2018.06.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jceh.2018.06.007","pdf_url":"http://www.jcehepatology.com/article/S097368831830094X/pdf","source":{"id":"https://openalex.org/S2764866434","display_name":"Journal of Clinical and Experimental Hepatology","issn_l":"0973-6883","issn":["0973-6883","2213-3453"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","ki-jl-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical and Experimental Hepatology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5677070","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6175739","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6175739","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6175739","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Exp Hepatol","raw_type":"Text"},{"id":"pmid:30302044","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30302044","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical and experimental hepatology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.jceh.2018.06.007","doi":"https://doi.org/10.1016/j.jceh.2018.06.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jceh.2018.06.007","pdf_url":"http://www.jcehepatology.com/article/S097368831830094X/pdf","source":{"id":"https://openalex.org/S2764866434","display_name":"Journal of Clinical and Experimental Hepatology","issn_l":"0973-6883","issn":["0973-6883","2213-3453"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","ki-jl-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical and Experimental Hepatology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306127","display_name":"U.S. Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98"},{"id":"https://openalex.org/F4320308400","display_name":"American Association for the Study of Liver Diseases","ror":"https://ror.org/005tjs461"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2808917216.pdf","grobid_xml":"https://content.openalex.org/works/W2808917216.grobid-xml"},"referenced_works_count":128,"referenced_works":["https://openalex.org/W981109825","https://openalex.org/W1043684383","https://openalex.org/W1480737421","https://openalex.org/W1570157225","https://openalex.org/W1572626374","https://openalex.org/W1590158608","https://openalex.org/W1608390320","https://openalex.org/W1768109898","https://openalex.org/W1845820577","https://openalex.org/W1850506588","https://openalex.org/W1964052519","https://openalex.org/W1965961643","https://openalex.org/W1969854592","https://openalex.org/W1971050542","https://openalex.org/W1971829840","https://openalex.org/W1972090383","https://openalex.org/W1972868549","https://openalex.org/W1973386884","https://openalex.org/W1974929635","https://openalex.org/W1976467306","https://openalex.org/W1976634473","https://openalex.org/W1976902190","https://openalex.org/W1978744572","https://openalex.org/W1979486195","https://openalex.org/W1979638087","https://openalex.org/W1982531948","https://openalex.org/W1984132292","https://openalex.org/W1984927454","https://openalex.org/W1985108110","https://openalex.org/W1986004422","https://openalex.org/W1987080089","https://openalex.org/W1988635965","https://openalex.org/W1989953010","https://openalex.org/W1991817028","https://openalex.org/W1992257441","https://openalex.org/W1993089591","https://openalex.org/W1994555844","https://openalex.org/W1997539276","https://openalex.org/W1998703443","https://openalex.org/W2000307707","https://openalex.org/W2005583061","https://openalex.org/W2007076123","https://openalex.org/W2007910534","https://openalex.org/W2008687444","https://openalex.org/W2010753690","https://openalex.org/W2013084498","https://openalex.org/W2013285484","https://openalex.org/W2016237837","https://openalex.org/W2018283382","https://openalex.org/W2018406010","https://openalex.org/W2019008972","https://openalex.org/W2019213314","https://openalex.org/W2023754888","https://openalex.org/W2024578017","https://openalex.org/W2025451263","https://openalex.org/W2026147918","https://openalex.org/W2028241033","https://openalex.org/W2028537535","https://openalex.org/W2028745555","https://openalex.org/W2032493663","https://openalex.org/W2034149599","https://openalex.org/W2035641119","https://openalex.org/W2037279364","https://openalex.org/W2037374867","https://openalex.org/W2038265222","https://openalex.org/W2040454026","https://openalex.org/W2053218539","https://openalex.org/W2054322556","https://openalex.org/W2057826142","https://openalex.org/W2061664741","https://openalex.org/W2063423157","https://openalex.org/W2069825714","https://openalex.org/W2076601347","https://openalex.org/W2076773572","https://openalex.org/W2082096421","https://openalex.org/W2082501489","https://openalex.org/W2083585063","https://openalex.org/W2086333383","https://openalex.org/W2086873275","https://openalex.org/W2091490498","https://openalex.org/W2092749570","https://openalex.org/W2093857021","https://openalex.org/W2095112199","https://openalex.org/W2095436231","https://openalex.org/W2104461353","https://openalex.org/W2106585100","https://openalex.org/W2107020136","https://openalex.org/W2109575393","https://openalex.org/W2121563579","https://openalex.org/W2124863154","https://openalex.org/W2126163424","https://openalex.org/W2127244067","https://openalex.org/W2129426344","https://openalex.org/W2135285816","https://openalex.org/W2142778330","https://openalex.org/W2142927752","https://openalex.org/W2144368832","https://openalex.org/W2148139066","https://openalex.org/W2148148169","https://openalex.org/W2153716096","https://openalex.org/W2160517174","https://openalex.org/W2182952544","https://openalex.org/W2189621653","https://openalex.org/W2288306858","https://openalex.org/W2305318049","https://openalex.org/W2318797776","https://openalex.org/W2333535893","https://openalex.org/W2345799316","https://openalex.org/W2405443453","https://openalex.org/W2408891949","https://openalex.org/W2419603248","https://openalex.org/W2467923959","https://openalex.org/W2518729378","https://openalex.org/W2530869149","https://openalex.org/W2557668316","https://openalex.org/W2569954374","https://openalex.org/W2572328462","https://openalex.org/W2583010566","https://openalex.org/W2591198683","https://openalex.org/W2591611981","https://openalex.org/W2615617633","https://openalex.org/W2744296566","https://openalex.org/W2774681187","https://openalex.org/W2793443582","https://openalex.org/W2794233713","https://openalex.org/W4236074613","https://openalex.org/W4302069398","https://openalex.org/W6730331131"],"related_works":["https://openalex.org/W1996200952","https://openalex.org/W2421248029","https://openalex.org/W89437166","https://openalex.org/W2019008972","https://openalex.org/W2795811709","https://openalex.org/W2377342145","https://openalex.org/W2183885024","https://openalex.org/W2037135410","https://openalex.org/W2041664971","https://openalex.org/W2778729522"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":20},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":18},{"year":2022,"cited_by_count":21},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-06-29T00:00:00"}
