{"id":"https://openalex.org/W2808755449","doi":"https://doi.org/10.1016/j.btre.2018.e00265","title":"Combined microbiological approach to screening of producers of proteases with hemostasis system proteins activity among micromycetes","display_name":"Combined microbiological approach to screening of producers of proteases with hemostasis system proteins activity among micromycetes","publication_year":2018,"publication_date":"2018-06-18","ids":{"openalex":"https://openalex.org/W2808755449","doi":"https://doi.org/10.1016/j.btre.2018.e00265","mag":"2808755449","pmid":"https://pubmed.ncbi.nlm.nih.gov/29992099","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6036644"},"language":"en","primary_location":{"id":"doi:10.1016/j.btre.2018.e00265","doi":"https://doi.org/10.1016/j.btre.2018.e00265","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.btre.2018.e00265","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2215017X1830033X/pdf","source":{"id":"https://openalex.org/S2764596916","display_name":"Biotechnology Reports","issn_l":"2215-017X","issn":["2215-017X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S2215017X1830033X/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041263780","display_name":"Alexander A. Osmolovskiy","orcid":"https://orcid.org/0000-0001-6672-0551","observed_orcids":["https://orcid.org/0000-0001-6672-0551"]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"Alexander A. Osmolovskiy","raw_affiliation_strings":["Department of Microbiology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian Federation","Faculty of Biotechnology, Lomonosov Moscow State University, Moscow, Russian Federation"],"raw_orcid":"https://orcid.org/0000-0001-6672-0551","affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian Federation","institution_ids":["https://openalex.org/I19880235"]},{"raw_affiliation_string":"Faculty of Biotechnology, Lomonosov Moscow State University, Moscow, Russian Federation","institution_ids":["https://openalex.org/I19880235"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022182547","display_name":"Anna A. Lukianova","orcid":"https://orcid.org/0000-0001-8069-7087","observed_orcids":["https://orcid.org/0000-0001-8069-7087"]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Anna A. Lukianova","raw_affiliation_strings":["Department of Microbiology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian Federation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian Federation","institution_ids":["https://openalex.org/I19880235"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005693226","display_name":"Elena S. Zvonareva","orcid":"https://orcid.org/0000-0002-4788-6991","observed_orcids":["https://orcid.org/0000-0002-4788-6991"]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Elena S. Zvonareva","raw_affiliation_strings":["Department of Microbiology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian Federation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian Federation","institution_ids":["https://openalex.org/I19880235"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072456524","display_name":"Valeriana G. Kreyer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Valeriana G. Kreyer","raw_affiliation_strings":["Department of Microbiology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian Federation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian Federation","institution_ids":["https://openalex.org/I19880235"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113725201","display_name":"Nina A. Baranova","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Nina A. Baranova","raw_affiliation_strings":["Department of Microbiology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian Federation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian Federation","institution_ids":["https://openalex.org/I19880235"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110564158","display_name":"Nikolay S. Egorov","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Nikolay S. Egorov","raw_affiliation_strings":["International Biotechnological Center, Lomonosov Moscow State University, Moscow, Russian Federation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Biotechnological Center, Lomonosov Moscow State University, Moscow, Russian Federation","institution_ids":["https://openalex.org/I19880235"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5041263780"],"corresponding_institution_ids":["https://openalex.org/I19880235"],"apc_list":{"value":3480,"currency":"USD","value_usd":3480},"apc_paid":{"value":3480,"currency":"USD","value_usd":3480},"fwci":0.154,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.38460097,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"19","issue":null,"first_page":"e00265","last_page":"e00265"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microfungi","display_name":"micromycetes","score":0.8690000176429749},{"id":"https://openalex.org/keywords/protease-screening","display_name":"protease screening","score":0.6489999890327454},{"id":"https://openalex.org/keywords/chromogenic-peptide-substrates","display_name":"chromogenic peptide substrates","score":0.9520000219345093},{"id":"https://openalex.org/keywords/human-plasma","display_name":"human plasma","score":0.656000018119812},{"id":"https://openalex.org/keywords/zymogen-activation","display_name":"zymogen activation","score":0.6610000133514404}],"concepts":[{"id":"https://openalex.org/C182220744","wikidata":"https://www.wikidata.org/wiki/Q7251226","display_name":"Proteases","level":3,"score":0.9818286895751953},{"id":"https://openalex.org/C2778589496","wikidata":"https://www.wikidata.org/wiki/Q487937","display_name":"Hemostasis","level":2,"score":0.8508613109588623},{"id":"https://openalex.org/C128463046","wikidata":"https://www.wikidata.org/wiki/Q22315590","display_name":"Chromogenic","level":2,"score":0.7005531787872314},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.6157331466674805},{"id":"https://openalex.org/C2776714187","wikidata":"https://www.wikidata.org/wiki/Q212410","display_name":"Protease","level":3,"score":0.5944629907608032},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5399470329284668},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5122806429862976},{"id":"https://openalex.org/C19014433","wikidata":"https://www.wikidata.org/wiki/Q5130995","display_name":"Cleave","level":3,"score":0.4752476215362549},{"id":"https://openalex.org/C2908981932","wikidata":"https://www.wikidata.org/wiki/Q212410","display_name":"Peptide Hydrolases","level":4,"score":0.4461393356323242},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.417364239692688},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2950870990753174},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.10576364398002625},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07088002562522888},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1016/j.btre.2018.e00265","doi":"https://doi.org/10.1016/j.btre.2018.e00265","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.btre.2018.e00265","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2215017X1830033X/pdf","source":{"id":"https://openalex.org/S2764596916","display_name":"Biotechnology Reports","issn_l":"2215-017X","issn":["2215-017X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology Reports","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4991537","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6036644","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6036644","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6036644","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnol Rep (Amst)","raw_type":"Text"},{"id":"pmid:29992099","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29992099","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology reports (Amsterdam, Netherlands)","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:cadd7e96bc0e4ffa8f071c2af63e549b","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/cadd7e96bc0e4ffa8f071c2af63e549b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biotechnology Reports, Vol 19, Iss , Pp - (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.btre.2018.e00265","doi":"https://doi.org/10.1016/j.btre.2018.e00265","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.btre.2018.e00265","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2215017X1830033X/pdf","source":{"id":"https://openalex.org/S2764596916","display_name":"Biotechnology Reports","issn_l":"2215-017X","issn":["2215-017X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4043000042438507,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320329591","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2808755449.pdf","grobid_xml":"https://content.openalex.org/works/W2808755449.grobid-xml"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W1967086489","https://openalex.org/W1972496463","https://openalex.org/W2002030140","https://openalex.org/W2008665651","https://openalex.org/W2048013243","https://openalex.org/W2069153156","https://openalex.org/W2088599011","https://openalex.org/W2114364192","https://openalex.org/W2161755146","https://openalex.org/W2165424636","https://openalex.org/W2319429891","https://openalex.org/W2401804412","https://openalex.org/W2563645414","https://openalex.org/W2597717818"],"related_works":["https://openalex.org/W7008154918","https://openalex.org/W3035426890","https://openalex.org/W2284145412","https://openalex.org/W6907475617","https://openalex.org/W2748317978","https://openalex.org/W6989365064","https://openalex.org/W7064374945","https://openalex.org/W7070901690","https://openalex.org/W2270272995","https://openalex.org/W2609459250"],"abstract_inverted_index":{"A":[0],"scheme":[1],"for":[2,30],"screening":[3],"of":[4,8,13,32,42,67],"micromycetes":[5],"-":[6],"producers":[7,44],"proteases":[9,43],"with":[10],"the":[11,24,33,40,65,68],"activity":[12,25],"hemostasis":[14,34,71],"system":[15,35],"proteins,":[16],"based":[17],"on":[18,39],"their":[19],"enzymatic":[20,50],"indices":[21],"determination":[22],"and":[23],"towards":[26],"chromogenic":[27],"peptide":[28],"substrates":[29],"proteins":[31],"was":[36],"developed.":[37],"Depending":[38],"ability":[41],"to":[45,63],"cleave":[46],"such":[47],"substrates,":[48],"an":[49],"reaction":[51],"in":[52],"conditions":[53],"containing":[54],"human":[55],"plasma":[56,70],"is":[57],"suggested,":[58],"which":[59],"makes":[60],"it":[61],"possible":[62],"identify":[64],"potentiality":[66],"target":[69],"proenzymes":[72],"activation.":[73]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-06-29T00:00:00"}