{"id":"https://openalex.org/W2808549339","doi":"https://doi.org/10.1038/s41598-018-27624-6","title":"Plasmonic Optical Imaging of Gold Nanorods Localization in Small Animals","display_name":"Plasmonic Optical Imaging of Gold Nanorods Localization in Small Animals","publication_year":2018,"publication_date":"2018-06-13","ids":{"openalex":"https://openalex.org/W2808549339","doi":"https://doi.org/10.1038/s41598-018-27624-6","mag":"2808549339","pmid":"https://pubmed.ncbi.nlm.nih.gov/29921960","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6008467"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-018-27624-6","doi":"https://doi.org/10.1038/s41598-018-27624-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-27624-6","pdf_url":"https://www.nature.com/articles/s41598-018-27624-6.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-018-27624-6.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025004615","display_name":"Keying Xu","orcid":"https://orcid.org/0000-0003-1981-4541","observed_orcids":["https://orcid.org/0000-0003-1981-4541","https://orcid.org/0009-0005-3426-1289"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Keying Xu","raw_affiliation_strings":["Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, 33146, USA","Department of Radiation Oncology, University of Miami School of Medicine, Miami, FL, 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, 33146, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Radiation Oncology, University of Miami School of Medicine, Miami, FL, 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016886878","display_name":"Junwei Shi","orcid":"https://orcid.org/0000-0002-7845-9212","observed_orcids":["https://orcid.org/0000-0002-7845-9212"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Junwei Shi","raw_affiliation_strings":["Department of Radiation Oncology, University of Miami School of Medicine, Miami, FL, 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University of Miami School of Medicine, Miami, FL, 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038744174","display_name":"Ali Pourmand","orcid":"https://orcid.org/0000-0002-5057-7495","observed_orcids":["https://orcid.org/0000-0002-5057-7495"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ali Pourmand","raw_affiliation_strings":["Department of Marine Geoscience, University of Miami RSMAS, Miami, FL, 33149, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Marine Geoscience, University of Miami RSMAS, Miami, FL, 33149, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111144763","display_name":"Thirupandiyur S. Udayakumar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thirupandiyur S. Udayakumar","raw_affiliation_strings":["Department of Radiation Oncology, University of Miami School of Medicine, Miami, FL, 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University of Miami School of Medicine, Miami, FL, 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109849825","display_name":"Nesrin Dogan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nesrin Dogan","raw_affiliation_strings":["Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, 33146, USA","Department of Radiation Oncology, University of Miami School of Medicine, Miami, FL, 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, 33146, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Radiation Oncology, University of Miami School of Medicine, Miami, FL, 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011519009","display_name":"Weizhao Zhao","orcid":"https://orcid.org/0000-0002-9890-5785","observed_orcids":["https://orcid.org/0000-0002-9890-5785"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Weizhao Zhao","raw_affiliation_strings":["Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, 33146, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, 33146, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063389942","display_name":"Alan S Pollack","orcid":"https://orcid.org/0000-0002-1801-2865","observed_orcids":["https://orcid.org/0000-0002-1801-2865"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alan Pollack","raw_affiliation_strings":["Department of Radiation Oncology, University of Miami School of Medicine, Miami, FL, 33136, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University of Miami School of Medicine, Miami, FL, 33136, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101482680","display_name":"Yidong Yang","orcid":"https://orcid.org/0000-0002-9036-1314","observed_orcids":["https://orcid.org/0000-0002-9036-1314"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Yidong Yang","raw_affiliation_strings":["Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, 33146, USA. yidongyang@miami.edu","Department of Radiation Oncology, University of Miami School of Medicine, Miami, FL, 33136, USA. yidongyang@miami.edu","Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, 33146, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, 33146, USA. yidongyang@miami.edu","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Radiation Oncology, University of Miami School of Medicine, Miami, FL, 33136, USA. yidongyang@miami.edu","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, 33146, USA","institution_ids":["https://openalex.org/I145608581"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5101482680"],"corresponding_institution_ids":["https://openalex.org/I145608581"],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":1.3792,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.79625954,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"8","issue":"1","first_page":"9342","last_page":"9342"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.016300000250339508,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gold-nanorods","display_name":"gold nanorods","score":0.9980000257492065},{"id":"https://openalex.org/keywords/surface-plasmon-resonance","display_name":"surface plasmon resonance","score":0.921999990940094},{"id":"https://openalex.org/keywords/diffuse-optical-tomography","display_name":"diffuse optical tomography","score":0.8939999938011169},{"id":"https://openalex.org/keywords/computed-tomography","display_name":"computed tomography","score":0.9039999842643738},{"id":"https://openalex.org/keywords/dual-modality-imaging","display_name":"dual-modality imaging","score":0.8640000224113464},{"id":"https://openalex.org/keywords/preclinical-imaging","display_name":"small animal imaging","score":0.7490000128746033},{"id":"https://openalex.org/keywords/whole-body-imaging","display_name":"whole-body imaging","score":0.41999998688697815},{"id":"https://openalex.org/keywords/breast-tumor-imaging","display_name":"breast tumor imaging","score":0.781000018119812},{"id":"https://openalex.org/keywords/passive-targeting","display_name":"passive targeting","score":0.7900000214576721},{"id":"https://openalex.org/keywords/enhanced-permeability-and-retention-effect","display_name":"enhanced permeability and retention effect","score":0.902999997138977},{"id":"https://openalex.org/keywords/tumor-imaging","display_name":"tumor imaging","score":0.5299999713897705}],"concepts":[{"id":"https://openalex.org/C126201875","wikidata":"https://www.wikidata.org/wiki/Q2684948","display_name":"Nanorod","level":2,"score":0.7470265626907349},{"id":"https://openalex.org/C136339569","wikidata":"https://www.wikidata.org/wiki/Q1142297","display_name":"Molecular imaging","level":3,"score":0.6840752363204956},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6430484652519226},{"id":"https://openalex.org/C104819515","wikidata":"https://www.wikidata.org/wiki/Q900961","display_name":"Colloidal gold","level":3,"score":0.595561683177948},{"id":"https://openalex.org/C29331040","wikidata":"https://www.wikidata.org/wiki/Q7239554","display_name":"Preclinical imaging","level":3,"score":0.5952324867248535},{"id":"https://openalex.org/C104293457","wikidata":"https://www.wikidata.org/wiki/Q28324852","display_name":"Imaging phantom","level":2,"score":0.5689795613288879},{"id":"https://openalex.org/C106847996","wikidata":"https://www.wikidata.org/wiki/Q898756","display_name":"Surface plasmon resonance","level":3,"score":0.5292954444885254},{"id":"https://openalex.org/C110879396","wikidata":"https://www.wikidata.org/wiki/Q58392","display_name":"Plasmon","level":2,"score":0.4848090708255768},{"id":"https://openalex.org/C145417883","wikidata":"https://www.wikidata.org/wiki/Q5275421","display_name":"Diffuse optical imaging","level":3,"score":0.4843536615371704},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.46398165822029114},{"id":"https://openalex.org/C92630104","wikidata":"https://www.wikidata.org/wiki/Q4115103","display_name":"Optical imaging","level":2,"score":0.4437703788280487},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.4324502646923065},{"id":"https://openalex.org/C2777807558","wikidata":"https://www.wikidata.org/wiki/Q4914764","display_name":"Biodistribution","level":3,"score":0.424739807844162},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3965384364128113},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.379777729511261},{"id":"https://openalex.org/C163716698","wikidata":"https://www.wikidata.org/wiki/Q841267","display_name":"Tomography","level":2,"score":0.37632179260253906},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.3537401258945465},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3187735974788666},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.2866271138191223},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.21671602129936218},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.16473469138145447},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14216244220733643},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09530973434448242},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09463542699813843},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008819","descriptor_name":"Mice, Nude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D043942","descriptor_name":"Nanotubes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1038/s41598-018-27624-6","doi":"https://doi.org/10.1038/s41598-018-27624-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-27624-6","pdf_url":"https://www.nature.com/articles/s41598-018-27624-6.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4968118","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6008467","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6008467","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6008467","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmid:29921960","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29921960","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:6936d2a654ba4bbab1faa96e7b033228","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/6936d2a654ba4bbab1faa96e7b033228","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41598-018-27624-6","doi":"https://doi.org/10.1038/s41598-018-27624-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-27624-6","pdf_url":"https://www.nature.com/articles/s41598-018-27624-6.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2808549339.pdf","grobid_xml":"https://content.openalex.org/works/W2808549339.grobid-xml"},"referenced_works_count":77,"referenced_works":["https://openalex.org/W1807543431","https://openalex.org/W1912693941","https://openalex.org/W1963831914","https://openalex.org/W1964569755","https://openalex.org/W1966808455","https://openalex.org/W1969117378","https://openalex.org/W1970838842","https://openalex.org/W1972730986","https://openalex.org/W1976041621","https://openalex.org/W1982136624","https://openalex.org/W1993340565","https://openalex.org/W1996385697","https://openalex.org/W1999242630","https://openalex.org/W1999364829","https://openalex.org/W1999451640","https://openalex.org/W2007492138","https://openalex.org/W2012339200","https://openalex.org/W2013807003","https://openalex.org/W2016052416","https://openalex.org/W2017071862","https://openalex.org/W2022953556","https://openalex.org/W2028188552","https://openalex.org/W2037048276","https://openalex.org/W2046031025","https://openalex.org/W2046669455","https://openalex.org/W2052181797","https://openalex.org/W2061294304","https://openalex.org/W2062317349","https://openalex.org/W2067413419","https://openalex.org/W2068670668","https://openalex.org/W2071404056","https://openalex.org/W2078571932","https://openalex.org/W2086696748","https://openalex.org/W2087031501","https://openalex.org/W2089061682","https://openalex.org/W2093385788","https://openalex.org/W2095754197","https://openalex.org/W2096023971","https://openalex.org/W2110721989","https://openalex.org/W2111216870","https://openalex.org/W2115712044","https://openalex.org/W2116670113","https://openalex.org/W2118737408","https://openalex.org/W2119162254","https://openalex.org/W2119608827","https://openalex.org/W2125753084","https://openalex.org/W2128721851","https://openalex.org/W2132331298","https://openalex.org/W2132878125","https://openalex.org/W2134049412","https://openalex.org/W2136456461","https://openalex.org/W2142483254","https://openalex.org/W2144405385","https://openalex.org/W2151932033","https://openalex.org/W2152801992","https://openalex.org/W2153771870","https://openalex.org/W2157812230","https://openalex.org/W2169935136","https://openalex.org/W2170957156","https://openalex.org/W2233826063","https://openalex.org/W2237089538","https://openalex.org/W2288065361","https://openalex.org/W2293988965","https://openalex.org/W2326912928","https://openalex.org/W2344028450","https://openalex.org/W2397546497","https://openalex.org/W2466179174","https://openalex.org/W2498197214","https://openalex.org/W2498425464","https://openalex.org/W2570042395","https://openalex.org/W2586656755","https://openalex.org/W2600935843","https://openalex.org/W2739067653","https://openalex.org/W2797517781","https://openalex.org/W3145545648","https://openalex.org/W4205743212","https://openalex.org/W4234368842"],"related_works":["https://openalex.org/W2107562630","https://openalex.org/W2040294619","https://openalex.org/W2055877195","https://openalex.org/W1996721839","https://openalex.org/W2981748249","https://openalex.org/W2039241300","https://openalex.org/W2045664198","https://openalex.org/W2019943575","https://openalex.org/W2016909008","https://openalex.org/W1975638220"],"abstract_inverted_index":{"Gold":[0],"nanoparticles":[1],"(GNP)":[2],"have":[3],"been":[4,35],"intensively":[5],"investigated":[6,118],"for":[7,27,99],"applications":[8],"in":[9,69,107,151,173,177],"cancer":[10],"imaging":[11,15,25,32,54,77,114,185],"and":[12,86,96,122,156,208],"therapy.":[13],"Most":[14],"studies":[16],"focused":[17],"on":[18,205],"microscopic":[19],"imaging.":[20,164],"Their":[21],"potential":[22],"as":[23],"optical":[24,53,88,113],"probes":[26],"whole":[28],"body":[29],"small":[30,70,178],"animal":[31,94],"has":[33],"rarely":[34],"explored.":[36],"Taking":[37],"advantage":[38],"of":[39,60,64,80,105,127,171],"their":[40],"surface":[41],"plasmon":[42],"resonance":[43],"(SPR)":[44],"properties,":[45],"we":[46],"aim":[47],"to":[48,56,195],"develop":[49],"a":[50,61],"noninvasive":[51],"diffuse":[52,87],"method":[55],"map":[57],"the":[58,93,103,108,152,168],"distribution":[59,104,126],"special":[62],"type":[63],"GNP,":[65],"gold":[66],"nanorods":[67],"(GNR),":[68],"animals.":[71,179],"We":[72],"developed":[73],"an":[74],"integrated":[75],"dual-modality":[76],"system":[78],"capable":[79],"both":[81],"x-ray":[82,163],"computed":[83],"tomography":[84,89],"(XCT)":[85],"(DOT).":[90],"XCT":[91],"provides":[92],"anatomy":[95],"contour":[97],"required":[98],"DOT;":[100],"DOT":[101],"maps":[102],"GNR":[106,128,146,175,189,200],"animal.":[109],"This":[110,165],"SPR":[111],"enhanced":[112,206],"(SPROI)":[115],"technique":[116],"was":[117,138],"using":[119,214],"simulation,":[120],"phantom":[121],"mouse":[123,153],"experiments.":[124],"The":[125],"at":[129,147],"various":[130],"concentrations":[131],"(0.1-100":[132],"nM,":[133],"or":[134,210],"3.5":[135],"ug/g-3.5":[136],"mg/g)":[137],"successfully":[139],"reconstructed":[140],"from":[141],"centimeter-scaled":[142],"volumes.":[143],"SPROI":[144,172,191],"detected":[145],"18":[148],"\u03bcg/g":[149],"concentration":[150],"breast":[154],"tumor,":[155],"is":[157],"3":[158],"orders":[159],"more":[160],"sensitive":[161],"than":[162,188],"study":[166],"demonstrated":[167],"high":[169],"sensitivity":[170],"mapping":[174],"distributions":[176],"It":[180],"does":[181],"not":[182],"require":[183],"additional":[184],"tags":[186],"other":[187],"themselves.":[190],"can":[192],"be":[193],"used":[194],"detect":[196],"tumors":[197],"targeted":[198],"by":[199],"via":[201,211],"passive":[202],"targeting":[203,213],"based":[204],"permeability":[207],"retention":[209],"active":[212],"biologically":[215],"conjugated":[216],"ligands.":[217]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-06-21T00:00:00"}
