{"id":"https://openalex.org/W2808419342","doi":null,"title":"Nuclear Response to Low Intensity Vibrations","display_name":"Nuclear Response to Low Intensity Vibrations","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2808419342","mag":"2808419342"},"language":"en","primary_location":{"id":"pmh:oai:scholarworks.boisestate.edu:under_conf_2018-1101","doi":null,"is_oa":false,"landing_page_url":"https://scholarworks.boisestate.edu/under_conf_2018/49","pdf_url":null,"source":{"id":"https://openalex.org/S4306400258","display_name":"ScholarWorks (Boise State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I120156002","host_organization_name":"Boise State University","host_organization_lineage":["https://openalex.org/I120156002"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"2018 Undergraduate Research and Scholarship Conference","raw_type":"text"},"volume":null,"type":"conference-paper","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054982743","display_name":"Josh Newberg","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Josh Newberg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006342421","display_name":"Jesse Schimpf","orcid":"https://orcid.org/0000-0003-2977-1549","observed_orcids":["https://orcid.org/0000-0003-2977-1549"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jesse Schimpf","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5056327870","display_name":"Paul H. Davis","orcid":"https://orcid.org/0000-0001-7333-8748","observed_orcids":["https://orcid.org/0000-0001-7333-8748"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul H. Davis","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7333-8748","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.07185629,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.7480000257492065,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.7480000257492065,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12269","display_name":"Effects of Vibration on Health","score":0.1680999994277954,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.061900001019239426,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nuclear-mechanics","display_name":"nuclear mechanics","score":0.7250000238418579},{"id":"https://openalex.org/keywords/low-intensity-vibration","display_name":"low-intensity vibration","score":0.9629999995231628},{"id":"https://openalex.org/keywords/nuclear-stiffness","display_name":"nuclear stiffness","score":0.6420000195503235},{"id":"https://openalex.org/keywords/inside-out-signaling","display_name":"inside-out signaling","score":0.9739999771118164},{"id":"https://openalex.org/keywords/outside-in-signaling","display_name":"outside-in signaling","score":0.8309999704360962},{"id":"https://openalex.org/keywords/cytoskeleton","display_name":"cytoskeleton","score":0.7409999966621399},{"id":"https://openalex.org/keywords/isolated-nuclei","display_name":"isolated nuclei","score":0.5669999718666077},{"id":"https://openalex.org/keywords/nuclear-organization","display_name":"nuclear organization","score":0.36500000953674316},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.7699999809265137},{"id":"https://openalex.org/keywords/exercise-mimetics","display_name":"exercise mimetics","score":0.6549999713897705}],"concepts":[{"id":"https://openalex.org/C93038891","wikidata":"https://www.wikidata.org/wiki/Q1061524","display_name":"Intensity (physics)","level":2,"score":0.5043174028396606},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.32933276891708374},{"id":"https://openalex.org/C39432304","wikidata":"https://www.wikidata.org/wiki/Q188847","display_name":"Environmental science","level":0,"score":0.32559239864349365},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.32409897446632385},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.1213516891002655}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:scholarworks.boisestate.edu:under_conf_2018-1101","doi":null,"is_oa":false,"landing_page_url":"https://scholarworks.boisestate.edu/under_conf_2018/49","pdf_url":null,"source":{"id":"https://openalex.org/S4306400258","display_name":"ScholarWorks (Boise State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I120156002","host_organization_name":"Boise State University","host_organization_lineage":["https://openalex.org/I120156002"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"2018 Undergraduate Research and Scholarship Conference","raw_type":"text"},{"id":"mag:2808419342","doi":null,"is_oa":false,"landing_page_url":"https://scholarworks.boisestate.edu/under_conf_2018/49/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4246117336","https://openalex.org/W3082773851","https://openalex.org/W4409355650","https://openalex.org/W2792303113","https://openalex.org/W7036479591","https://openalex.org/W4220898366","https://openalex.org/W1971563489","https://openalex.org/W2256535442","https://openalex.org/W1222967933","https://openalex.org/W2657694447"],"abstract_inverted_index":{"The":[0],"nucleus,":[1],"central":[2],"to":[3,19,34,50,58,77,81,97,123,128,141,146,152],"all":[4],"cellular":[5],"activity,":[6],"relies":[7],"on":[8],"both":[9,68],"direct":[10],"mechanical":[11,82,144,179],"input":[12],"as":[13,15,188],"well":[14],"its":[16],"molecular":[17],"transducers":[18],"sense":[20,78],"external":[21],"stimuli":[22],"and":[23,38,52,71,79,91,160],"respond":[24],"by":[25],"regulating":[26],"intra-nuclear":[27],"organization":[28],"that":[29,44,67,117,181],"ultimately":[30],"determines":[31],"gene":[32],"expression":[33],"control":[35],"cell":[36,60,118,187],"function":[37],"fate.":[39],"It":[40],"is":[41],"long":[42],"studied":[43],"signals":[45],"propagate":[46],"from":[47,139,171],"extracellular":[48],"environment":[49],"cytoskeleton":[51,70,92],"into":[53],"the":[54,69,110,178,182,186],"nucleus":[55,72,111,183],"(outside-in":[56],"signaling)":[57],"regulate":[59],"behavior.":[61],"Emerging":[62],"evidence,":[63],"however,":[64],"has":[65],"shown":[66],"have":[73],"an":[74,189],"inherent":[75],"ability":[76],"adapt":[80,122],"force":[83,167],"independent":[84],"of":[85,177],"each":[86],"other.":[87],"This":[88],"suggests":[89],"mechano-signaling":[90],"remodeling":[93],"events":[94],"in":[95,126,185],"response":[96,127],"exercise":[98],"mimetics,":[99],"like":[100],"low":[101,154],"intensity":[102,155],"vibration":[103,156],"(LIV),":[104],"may":[105],"directly":[106,121],"be":[107],"sensed":[108],"at":[109],"(inside-out":[112],"signaling).":[113],"Here":[114],"we":[115,135],"hypothesize":[116],"nuclei":[119,138,149],"will":[120,174],"dynamic":[124],"accelerations":[125],"LIV.":[129,147],"To":[130],"answer":[131],"this":[132,172],"question":[133],"directly,":[134],"isolated":[136],"live":[137],"cells":[140],"test":[142],"their":[143,161],"responses":[145],"Isolated":[148],"are":[150],"introduced":[151],"a":[153],"(LIV,":[157],"0.7g,":[158],"90Hz)":[159],"stiffness\u2019":[162],"measured":[163],"via":[164],"AFM":[165],"(Atomic":[166],"microscope)":[168],"protocol.":[169],"Findings":[170],"study":[173],"allow":[175],"evaluation":[176],"role":[180],"plays":[184],"individual":[190],"organelle.":[191]},"counts_by_year":[],"updated_date":"2026-09-11T09:22:31.653822","created_date":"2018-06-21T00:00:00"}