{"id":"https://openalex.org/W2808269682","doi":"https://doi.org/10.1039/c8bm00454d","title":"Black TiO 2 -based nanoprobes for T 1 -weighted MRI-guided photothermal therapy in CD133 high expressed pancreatic cancer stem-like cells","display_name":"Black TiO 2 -based nanoprobes for T 1 -weighted MRI-guided photothermal therapy in CD133 high expressed pancreatic cancer stem-like cells","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2808269682","doi":"https://doi.org/10.1039/c8bm00454d","mag":"2808269682","pmid":"https://pubmed.ncbi.nlm.nih.gov/29947365"},"language":"en","primary_location":{"id":"doi:10.1039/c8bm00454d","doi":"https://doi.org/10.1039/c8bm00454d","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c8bm00454d","pdf_url":null,"source":{"id":"https://openalex.org/S2494179437","display_name":"Biomaterials Science","issn_l":"2047-4830","issn":["2047-4830","2047-4849"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100420070","display_name":"Siqi Wang","orcid":"https://orcid.org/0000-0002-2179-620X","observed_orcids":["https://orcid.org/0000-0002-2179-620X"]},"institutions":[{"id":"https://openalex.org/I109935558","display_name":"Ningbo University","ror":"https://ror.org/03et85d35","country_code":"CN","type":"education","lineage":["https://openalex.org/I109935558"]},{"id":"https://openalex.org/I4210153915","display_name":"Ningbo University Affiliated Hospital","ror":"https://ror.org/045rymn14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Siqi Wang","raw_affiliation_strings":["China","Department of Radiology","Ningbo","Ningbo University School of Medicine","The Affiliated Hospital of Medical School of Ningbo University","Department of Radiology, The Affiliated Hospital of Medical School of Ningbo University, Ningbo University School of Medicine, Ningbo, Zhejiang Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"Department of Radiology","institution_ids":[]},{"raw_affiliation_string":"Ningbo","institution_ids":[]},{"raw_affiliation_string":"Ningbo University School of Medicine","institution_ids":["https://openalex.org/I109935558"]},{"raw_affiliation_string":"The Affiliated Hospital of Medical School of Ningbo University","institution_ids":["https://openalex.org/I109935558","https://openalex.org/I4210153915"]},{"raw_affiliation_string":"Department of Radiology, The Affiliated Hospital of Medical School of Ningbo University, Ningbo University School of Medicine, Ningbo, Zhejiang Province, China","institution_ids":["https://openalex.org/I109935558","https://openalex.org/I4210153915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076693830","display_name":"Wenzhi Ren","orcid":"https://orcid.org/0000-0002-3794-8378","observed_orcids":["https://orcid.org/0000-0002-3794-8378"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I4210165339","display_name":"Ningbo Institute of Industrial Technology","ror":"https://ror.org/05nqg3g04","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165339"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenzhi Ren","raw_affiliation_strings":["CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices","China","Chinese Academy of Sciences","Ningbo","Ningbo Institute of Materials Technology and Engineering","CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, 1219 ZhongGuan West Road, Ningbo, China","University of Chinese Academy of Sciences, No. 19(A) Yuquan Road, Shijingshan District, Beijing, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"Chinese Academy of Sciences","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"Ningbo","institution_ids":[]},{"raw_affiliation_string":"Ningbo Institute of Materials Technology and Engineering","institution_ids":["https://openalex.org/I4210165339"]},{"raw_affiliation_string":"CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, 1219 ZhongGuan West Road, Ningbo, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210165339"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, No. 19(A) Yuquan Road, Shijingshan District, Beijing, P.R. China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100420053","display_name":"Jianhua Wang","orcid":"https://orcid.org/0000-0003-2175-3610","observed_orcids":["https://orcid.org/0000-0003-2175-3610"]},"institutions":[{"id":"https://openalex.org/I109935558","display_name":"Ningbo University","ror":"https://ror.org/03et85d35","country_code":"CN","type":"education","lineage":["https://openalex.org/I109935558"]},{"id":"https://openalex.org/I4210153915","display_name":"Ningbo University Affiliated Hospital","ror":"https://ror.org/045rymn14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153915"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jianhua Wang","raw_affiliation_strings":["China","Department of Radiology","Ningbo","Ningbo University School of Medicine","The Affiliated Hospital of Medical School of Ningbo University","Department of Radiology, The Affiliated Hospital of Medical School of Ningbo University, Ningbo University School of Medicine, Ningbo, Zhejiang Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"Department of Radiology","institution_ids":[]},{"raw_affiliation_string":"Ningbo","institution_ids":[]},{"raw_affiliation_string":"Ningbo University School of Medicine","institution_ids":["https://openalex.org/I109935558"]},{"raw_affiliation_string":"The Affiliated Hospital of Medical School of Ningbo University","institution_ids":["https://openalex.org/I109935558","https://openalex.org/I4210153915"]},{"raw_affiliation_string":"Department of Radiology, The Affiliated Hospital of Medical School of Ningbo University, Ningbo University School of Medicine, Ningbo, Zhejiang Province, China","institution_ids":["https://openalex.org/I109935558","https://openalex.org/I4210153915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026179498","display_name":"Zhenqi Jiang","orcid":"https://orcid.org/0000-0002-2685-1327","observed_orcids":["https://orcid.org/0000-0002-2685-1327"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I4210165339","display_name":"Ningbo Institute of Industrial Technology","ror":"https://ror.org/05nqg3g04","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165339"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhenqi Jiang","raw_affiliation_strings":["CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices","China","Chinese Academy of Sciences","Ningbo","Ningbo Institute of Materials Technology and Engineering","CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, 1219 ZhongGuan West Road, Ningbo, China","University of Chinese Academy of Sciences, No. 19(A) Yuquan Road, Shijingshan District, Beijing, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"Chinese Academy of Sciences","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"Ningbo","institution_ids":[]},{"raw_affiliation_string":"Ningbo Institute of Materials Technology and Engineering","institution_ids":["https://openalex.org/I4210165339"]},{"raw_affiliation_string":"CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, 1219 ZhongGuan West Road, Ningbo, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210165339"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, No. 19(A) Yuquan Road, Shijingshan District, Beijing, P.R. China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055222256","display_name":"Madiha Saeed","orcid":"https://orcid.org/0000-0003-2355-5167","observed_orcids":["https://orcid.org/0000-0003-2355-5167"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]},{"id":"https://openalex.org/I4210165339","display_name":"Ningbo Institute of Industrial Technology","ror":"https://ror.org/05nqg3g04","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165339"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Madiha Saeed","raw_affiliation_strings":["CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices","China","Chinese Academy of Sciences","Ningbo","Ningbo Institute of Materials Technology and Engineering","CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, 1219 ZhongGuan West Road, Ningbo, China","University of Chinese Academy of Sciences, No. 19(A) Yuquan Road, Shijingshan District, Beijing, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"Chinese Academy of Sciences","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"Ningbo","institution_ids":[]},{"raw_affiliation_string":"Ningbo Institute of Materials Technology and Engineering","institution_ids":["https://openalex.org/I4210165339"]},{"raw_affiliation_string":"CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, 1219 ZhongGuan West Road, Ningbo, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210165339"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences, No. 19(A) Yuquan Road, Shijingshan District, Beijing, P.R. China","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100461198","display_name":"Lili Zhang","orcid":"https://orcid.org/0000-0002-7385-2445","observed_orcids":["https://orcid.org/0000-0002-7385-2445","https://orcid.org/0009-0009-3027-4102"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210123885","display_name":"Shanghai Institute of Applied Physics","ror":"https://ror.org/02w6gr951","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210123885"]},{"id":"https://openalex.org/I4391768149","display_name":"Shanghai Synchrotron Radiation Facility","ror":"https://ror.org/02ys41z83","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768149"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lili Zhang","raw_affiliation_strings":["China","Chinese Academy of Sciences","Shanghai","Shanghai Institute of Applied Physics","Shanghai Synchrotron Radiation Facility"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"Chinese Academy of Sciences","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"Shanghai","institution_ids":[]},{"raw_affiliation_string":"Shanghai Institute of Applied Physics","institution_ids":["https://openalex.org/I4210123885"]},{"raw_affiliation_string":"Shanghai Synchrotron Radiation Facility","institution_ids":["https://openalex.org/I4391768149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103257017","display_name":"Aiguo Li","orcid":"https://orcid.org/0000-0003-0039-3695","observed_orcids":["https://orcid.org/0000-0003-0039-3695"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210123885","display_name":"Shanghai Institute of Applied Physics","ror":"https://ror.org/02w6gr951","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210123885"]},{"id":"https://openalex.org/I4391768149","display_name":"Shanghai Synchrotron Radiation Facility","ror":"https://ror.org/02ys41z83","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768149"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Aiguo Li","raw_affiliation_strings":["China","Chinese Academy of Sciences","Shanghai","Shanghai Institute of Applied Physics","Shanghai Synchrotron Radiation Facility","Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"Chinese Academy of Sciences","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"Shanghai","institution_ids":[]},{"raw_affiliation_string":"Shanghai Institute of Applied Physics","institution_ids":["https://openalex.org/I4210123885"]},{"raw_affiliation_string":"Shanghai Synchrotron Radiation Facility","institution_ids":["https://openalex.org/I4391768149"]},{"raw_affiliation_string":"Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210123885","https://openalex.org/I4391768149"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021213624","display_name":"Aiguo Wu","orcid":"https://orcid.org/0000-0001-7200-8923","observed_orcids":["https://orcid.org/0000-0001-7200-8923"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210165339","display_name":"Ningbo Institute of Industrial Technology","ror":"https://ror.org/05nqg3g04","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165339"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Aiguo Wu","raw_affiliation_strings":["CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices","China","Chinese Academy of Sciences","Ningbo","Ningbo Institute of Materials Technology and Engineering","CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, 1219 ZhongGuan West Road, Ningbo, China"],"raw_orcid":"https://orcid.org/0000-0001-7200-8923","affiliations":[{"raw_affiliation_string":"CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"Chinese Academy of Sciences","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"Ningbo","institution_ids":[]},{"raw_affiliation_string":"Ningbo Institute of Materials Technology and Engineering","institution_ids":["https://openalex.org/I4210165339"]},{"raw_affiliation_string":"CAS Key Laboratory of Magnetic Materials and Devices & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province& Division of Functional Materials and Nanodevices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, 1219 ZhongGuan West Road, Ningbo, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210165339"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5021213624","https://openalex.org/A5100420053"],"corresponding_institution_ids":["https://openalex.org/I109935558","https://openalex.org/I19820366","https://openalex.org/I4210153915","https://openalex.org/I4210165339"],"apc_list":null,"apc_paid":null,"fwci":1.7773,"has_fulltext":false,"cited_by_count":51,"citation_normalized_percentile":{"value":0.83578856,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"6","issue":"8","first_page":"2209","last_page":"2218"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cd133","display_name":"CD133","score":0.8600000143051147},{"id":"https://openalex.org/keywords/pancreatic-cancer-stem-cells","display_name":"pancreatic cancer stem cells","score":0.9589999914169312},{"id":"https://openalex.org/keywords/gd-dota","display_name":"Gd-DOTA","score":0.9229999780654907},{"id":"https://openalex.org/keywords/monoclonal-antibody-targeting","display_name":"monoclonal antibody targeting","score":0.8799999952316284},{"id":"https://openalex.org/keywords/theranostics","display_name":"theranostics","score":0.7699999809265137},{"id":"https://openalex.org/keywords/near-infrared-laser","display_name":"near-infrared laser","score":0.6209999918937683},{"id":"https://openalex.org/keywords/panc-1-cells","display_name":"PANC-1 cells","score":0.8759999871253967},{"id":"https://openalex.org/keywords/r1-relaxivity","display_name":"T1 relaxivity","score":0.7110000252723694},{"id":"https://openalex.org/keywords/active-targeting","display_name":"active targeting","score":0.5090000033378601}],"concepts":[{"id":"https://openalex.org/C182606246","wikidata":"https://www.wikidata.org/wiki/Q7187926","display_name":"Photothermal therapy","level":2,"score":0.7031049132347107},{"id":"https://openalex.org/C2780210213","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic cancer","level":3,"score":0.6156485676765442},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.49051183462142944},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.45324695110321045},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38979965448379517},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.38642966747283936},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.3781879246234894},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.33315736055374146},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.30112576484680176},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.27775853872299194},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26481950283050537},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23219725489616394},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1668170690536499},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.15988710522651672}],"mesh":[{"descriptor_ui":"D000071916","descriptor_name":"AC133 Antigen","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010316","descriptor_name":"Particle Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010789","descriptor_name":"Phototherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013499","descriptor_name":"Surface Properties","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014025","descriptor_name":"Titanium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014025","descriptor_name":"Titanium","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D061848","descriptor_name":"Optical Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1039/c8bm00454d","doi":"https://doi.org/10.1039/c8bm00454d","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c8bm00454d","pdf_url":null,"source":{"id":"https://openalex.org/S2494179437","display_name":"Biomaterials Science","issn_l":"2047-4830","issn":["2047-4830","2047-4849"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials Science","raw_type":"journal-article"},{"id":"pmid:29947365","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29947365","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials science","raw_type":"Journal Article"},{"id":"pmh:oai:ir.nimte.ac.cn/:174433/17269","doi":null,"is_oa":false,"landing_page_url":"http://ir.nimte.ac.cn/handle/174433/17269","pdf_url":null,"source":{"id":"https://openalex.org/S7407064368","display_name":"Ningbo Institute of Materials Technology and Engineering, CAS Institutional Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"\u671f\u520a\u8bba\u6587"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1891198803","display_name":"\u80bf\u7624\u5fae\u8840\u7ba1\u4e0e\u5b9e\u4f53\u7624\u53cc\u9776\u5411\u578b\u8d85\u58f0\u6fc0\u53d1TiO2\u57fa-MRI\u589e\u5f3a\u590d\u5408\u5242\u53ca\u5176\u58f0\u52a8\u529b\u6cbb\u7597\u4e0e\u53ef\u89c6\u5316\u7814\u7a76","funder_award_id":"U1432114","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G327225820","display_name":null,"funder_award_id":"2017C110022","funder_id":"https://openalex.org/F4320324778","funder_display_name":"Ningbo Municipal Bureau of Science and Technology"},{"id":"https://openalex.org/G3597220373","display_name":null,"funder_award_id":"2010735","funder_id":"https://openalex.org/F4320321133","funder_display_name":"Chinese Academy of Sciences"},{"id":"https://openalex.org/G5259855308","display_name":null,"funder_award_id":"3171101059","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7681241545","display_name":null,"funder_award_id":"2015B11002","funder_id":"https://openalex.org/F4320324778","funder_display_name":"Ningbo Municipal Bureau of Science and Technology"},{"id":"https://openalex.org/G8482001119","display_name":null,"funder_award_id":"U1501501","funder_id":"https://openalex.org/F4320321921","funder_display_name":"Natural Science Foundation of Guangdong Province"},{"id":"https://openalex.org/G8576119584","display_name":null,"funder_award_id":"2015C50004","funder_id":"https://openalex.org/F4320324778","funder_display_name":"Ningbo Municipal Bureau of Science and Technology"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321133","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35"},{"id":"https://openalex.org/F4320321921","display_name":"Natural Science Foundation of Guangdong Province","ror":null},{"id":"https://openalex.org/F4320324778","display_name":"Ningbo Municipal Bureau of Science and Technology","ror":"https://ror.org/00gskyj95"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W282419368","https://openalex.org/W1417694865","https://openalex.org/W1878780595","https://openalex.org/W1982213157","https://openalex.org/W1993854433","https://openalex.org/W1994070275","https://openalex.org/W2004136003","https://openalex.org/W2033503179","https://openalex.org/W2037725619","https://openalex.org/W2082823320","https://openalex.org/W2119034368","https://openalex.org/W2131170195","https://openalex.org/W2156631561","https://openalex.org/W2236332245","https://openalex.org/W2302439279","https://openalex.org/W2415162963","https://openalex.org/W2460425371","https://openalex.org/W2547783897","https://openalex.org/W2605513698","https://openalex.org/W2611437168","https://openalex.org/W2730901300","https://openalex.org/W2734693461","https://openalex.org/W2745662791","https://openalex.org/W2756913513","https://openalex.org/W2766497113","https://openalex.org/W2767321384","https://openalex.org/W2769558393","https://openalex.org/W2771639621","https://openalex.org/W2776396536","https://openalex.org/W2781525129","https://openalex.org/W2789682580","https://openalex.org/W2795487963"],"related_works":["https://openalex.org/W4283828569","https://openalex.org/W6920805738","https://openalex.org/W4399329788","https://openalex.org/W4389761965","https://openalex.org/W2906374864","https://openalex.org/W2996157087","https://openalex.org/W3208038826","https://openalex.org/W4220849827","https://openalex.org/W2911291235","https://openalex.org/W2727956527"],"abstract_inverted_index":{"At":[0],"present,":[1],"transmembrane":[2],"glycoprotein":[3],"CD133":[4,85,101,153],"highly":[5,86,154],"expressed":[6,87,155],"pancreatic":[7,33,71,210],"cancer":[8,211,229],"stem":[9,214],"cells":[10,157],"(PCSCs),":[11],"with":[12,46,76,149],"the":[13,25,42,47,62,77,115,120,139,170,194,206,220,226],"features":[14],"of":[15,28,49,70,79,119,130,209,222,228],"chemotherapeutic/radiotherapeutic":[16],"resistance":[17],"and":[18,30,35,94,100,160,178,186,212],"exclusive":[19],"tumorigenic":[20],"potential,":[21],"are":[22,37],"considered":[23],"as":[24,57,144,162],"primary":[26],"cause":[27],"metastasis":[29],"recurrence":[31],"in":[32,41,84,175,193,225],"cancer,":[34],"therefore":[36],"an":[38,58],"effective":[39,207],"target":[40],"disease":[43],"treatment.":[44],"Furthermore,":[45],"launch":[48],"precision":[50],"medicine,":[51],"multifunctional":[52],"nanoprobes":[53,91,121,140,171],"have":[54,141],"been":[55],"applied":[56],"efficient":[59],"strategy":[60,204],"for":[61,205],"magnetic":[63],"resonance":[64],"imaging":[65,185],"(MRI)-guided":[66],"photothermal":[67],"therapy":[68],"(PTT)":[69],"cancer.":[72],"In":[73,165],"this":[74],"research,":[75],"aim":[78],"achieving":[80],"precise":[81],"MRI-guided":[82],"PTT":[83,191],"PCSCs,":[88],"novel":[89],"bTiO2-Gd-CD133mAb":[90],"were":[92,158],"designed":[93],"successfully":[95],"prepared":[96],"by":[97],"loading":[98],"Gd-DOTA":[99],"monoclonal":[102],"antibodies":[103],"on":[104],"black":[105,223],"TiO2":[106,224],"nanoparticles.":[107],"It":[108],"was":[109,122],"very":[110],"interesting":[111],"to":[112],"find":[113],"that":[114,129,138,169],"r1":[116],"relaxivity":[117],"value":[118],"34.394":[123],"mM-1":[124,134],"s-1,":[125],"about":[126],"7.5":[127],"times":[128],"commercial":[131],"Magnevist":[132],"(4.5624":[133],"s-1),":[135],"which":[136],"indicates":[137],"good":[142],"potential":[143],"MRI":[145],"T1":[146],"contrast":[147],"agents":[148],"excellent":[150],"performance.":[151],"Herein,":[152],"PANC-1":[156,176],"selected":[159],"verified":[161],"PCSCs":[163,195],"model.":[164,196],"vitro":[166],"experiments":[167],"demonstrated":[168],"exhibited":[172],"active-targeting":[173],"ability":[174],"cells,":[177,215],"consequently":[179],"could":[180],"specially":[181],"enhance":[182],"T1-weighted":[183],"MR":[184],"808":[187],"nm":[188],"near-infrared":[189],"(NIR)-triggered":[190],"efficiency":[192],"Our":[197],"study":[198],"not":[199],"only":[200],"provides":[201],"a":[202],"new":[203],"treatment":[208],"its'":[213],"but":[216],"also":[217],"further":[218],"broadens":[219],"application":[221],"field":[227],"theranostics.":[230]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-06-21T00:00:00"}