{"id":"https://openalex.org/W2808218541","doi":null,"title":"Incremento de Linfocitos Intraepiteliales en pacientes con S\u00edndrome de Intestino Irritable","display_name":"Incremento de Linfocitos Intraepiteliales en pacientes con S\u00edndrome de Intestino Irritable","publication_year":2014,"publication_date":"2014-08-11","ids":{"openalex":"https://openalex.org/W2808218541","mag":"2808218541"},"language":"en","primary_location":{"id":"pmh:oai:americanae.aecid.es:3573588","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10757/324687","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Universidad Peruana de Ciencias Aplicadas (UPC)","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10757/324687","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Ar\u00e9valo, F.","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ar\u00e9valo, F.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013299698","display_name":"Violeta Arag\u00f3n","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aragon, V.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071737348","display_name":"Pedro Montes","orcid":"https://orcid.org/0000-0002-3510-3558","observed_orcids":["https://orcid.org/0000-0002-3510-3558"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Montes, P.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Guzm\u00e1n, E.","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guzm\u00e1n, E.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5009501283","display_name":"Eduardo Monge","orcid":"https://orcid.org/0000-0002-4212-8526","observed_orcids":["https://orcid.org/0000-0002-4212-8526"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Monge, E.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.41573525,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13569","display_name":"Microscopic Colitis","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intraepithelial-lymphocytes","display_name":"intraepithelial lymphocytes","score":0.9589999914169312},{"id":"https://openalex.org/keywords/irritable-bowel-syndrome","display_name":"irritable bowel syndrome","score":0.9860000014305115},{"id":"https://openalex.org/keywords/colonic-mucosa","display_name":"colonic mucosa","score":0.8370000123977661},{"id":"https://openalex.org/keywords/mast-cells","display_name":"mast cells","score":0.6959999799728394},{"id":"https://openalex.org/keywords/enterochromaffin-cells","display_name":"enterochromaffin cells","score":0.9959999918937683},{"id":"https://openalex.org/keywords/eosinophils","display_name":"eosinophils","score":0.9980000257492065},{"id":"https://openalex.org/keywords/colon-biopsy","display_name":"colon biopsy","score":0.5379999876022339},{"id":"https://openalex.org/keywords/histological-findings","display_name":"histological findings","score":0.4659999907016754},{"id":"https://openalex.org/keywords/lymphocytic-colitis","display_name":"lymphocytic colitis","score":0.8970000147819519}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8240082263946533},{"id":"https://openalex.org/C2778271842","wikidata":"https://www.wikidata.org/wiki/Q838966","display_name":"Irritable bowel syndrome","level":2,"score":0.5997628569602966},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4848884046077728},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3477741777896881}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:americanae.aecid.es:3573588","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10757/324687","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Universidad Peruana de Ciencias Aplicadas (UPC)","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:americanae.aecid.es:3573588","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10757/324687","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Universidad Peruana de Ciencias Aplicadas (UPC)","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4390289146","https://openalex.org/W1823519187","https://openalex.org/W2954935163","https://openalex.org/W2649322244","https://openalex.org/W1978912778","https://openalex.org/W2008709508","https://openalex.org/W4238660721","https://openalex.org/W3113425054","https://openalex.org/W3041802770","https://openalex.org/W2762728808"],"abstract_inverted_index":{"Several":[0],"studies":[1],"have":[2],"shown":[3],"increased":[4,82],"numbers":[5,83],"of":[6,17,25,84,93],"intraepithelial":[7],"lymphocytes":[8],"(IEL),":[9],"mast":[10,113],"cells,":[11,114],"enterochromaffin":[12,115],"cells":[13,116],"in":[14,39,51,86,112],"colonic":[15],"mucosa":[16],"patients":[18,55,70,87,94],"with":[19,56,59,74,88,95],"Irritable":[20],"Bowel":[21],"Syndrome":[22],"(IBS).":[23],"Many":[24],"these":[26],"findings":[27,49],"are":[28],"based":[29,31],"is":[30,36,44],"on":[32],"immunohistochemistry":[33],"results,":[34],"which":[35],"not":[37],"available":[38],"general":[40],"hospitals.":[41],"Our":[42],"objective":[43],"to":[45],"study":[46],"the":[47],"histological":[48,100],"observed":[50],"colon":[52],"biopsies":[53],"from":[54],"IBS":[57,75,89,96],"compared":[58],"a":[60],"group":[61,92],"without":[62,78],"IBS,":[63],"using":[64],"only":[65],"histochemistry.":[66],"Twenty":[67],"five":[68],"(25)":[69],"were":[71,105],"included:":[72],"16":[73],"and":[76],"9":[77],"IBS.":[79],"We":[80],"found":[81],"IEL":[85],"(p=0,002).":[90],"A":[91],"(41.9%)":[97],"who":[98],"fulfilled":[99],"criteria":[101],"for":[102],"lymphocytic":[103],"colitis":[104],"excluded.":[106],"There":[107],"was":[108],"no":[109],"significant":[110],"difference":[111],"or":[117],"eosinophils.":[118]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-10-10T00:00:00"}