{"id":"https://openalex.org/W2808065103","doi":"https://doi.org/10.1111/dom.13420","title":"Effects of liraglutide on gallbladder emptying: A randomized, placebo\u2010controlled trial in adults with overweight or obesity","display_name":"Effects of liraglutide on gallbladder emptying: A randomized, placebo\u2010controlled trial in adults with overweight or obesity","publication_year":2018,"publication_date":"2018-06-12","ids":{"openalex":"https://openalex.org/W2808065103","doi":"https://doi.org/10.1111/dom.13420","mag":"2808065103","pmid":"https://pubmed.ncbi.nlm.nih.gov/29892986","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6220792"},"language":"en","primary_location":{"id":"doi:10.1111/dom.13420","doi":"https://doi.org/10.1111/dom.13420","is_oa":true,"landing_page_url":"https://doi.org/10.1111/dom.13420","pdf_url":"https://www.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/dom.13420","source":{"id":"https://openalex.org/S148394532","display_name":"Diabetes Obesity and Metabolism","issn_l":"1462-8902","issn":["1462-8902","1463-1326"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, Obesity and Metabolism","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/dom.13420","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024813724","display_name":"Christina Nex\u00f8e-Larsen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802582725","display_name":"Gentofte Hospital","ror":"https://ror.org/051dzw862","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802582725"]},{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Christina C. Nex\u00f8e\u2010Larsen","raw_affiliation_strings":["Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark","institution_ids":["https://openalex.org/I2802582725","https://openalex.org/I4405255865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063342523","display_name":"P. Hove S\u00f8rensen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802582725","display_name":"Gentofte Hospital","ror":"https://ror.org/051dzw862","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802582725"]},{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Pernille H. S\u00f8rensen","raw_affiliation_strings":["Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark","institution_ids":["https://openalex.org/I2802582725","https://openalex.org/I4405255865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5118940995","display_name":"H\u00e9l\u00e8ne Hausner","orcid":"https://orcid.org/0000-0003-4271-6018","observed_orcids":["https://orcid.org/0000-0003-4271-6018"]},"institutions":[{"id":"https://openalex.org/I189090001","display_name":"Novo Nordisk (Denmark)","ror":"https://ror.org/0435rc536","country_code":"DK","type":"company","lineage":["https://openalex.org/I189090001","https://openalex.org/I2801134892","https://openalex.org/I4210159963"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Helene Hausner","raw_affiliation_strings":["Department of Clinical Pharmacology Novo Nordisk A/S  S\u00f8borg Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology Novo Nordisk A/S  S\u00f8borg Denmark","institution_ids":["https://openalex.org/I189090001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002259460","display_name":"Mikkel Askj\u00e6r Agersnap","orcid":"https://orcid.org/0000-0002-5827-5870","observed_orcids":["https://orcid.org/0000-0002-5827-5870"]},"institutions":[{"id":"https://openalex.org/I189090001","display_name":"Novo Nordisk (Denmark)","ror":"https://ror.org/0435rc536","country_code":"DK","type":"company","lineage":["https://openalex.org/I189090001","https://openalex.org/I2801134892","https://openalex.org/I4210159963"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Mikkel Agersnap","raw_affiliation_strings":["Department of Medicine and Science Novo Nordisk A/S  S\u00f8borg Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Science Novo Nordisk A/S  S\u00f8borg Denmark","institution_ids":["https://openalex.org/I189090001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014532906","display_name":"Mille Baekdal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802582725","display_name":"Gentofte Hospital","ror":"https://ror.org/051dzw862","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802582725"]},{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Mille Baekdal","raw_affiliation_strings":["Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark","institution_ids":["https://openalex.org/I2802582725","https://openalex.org/I4405255865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024869586","display_name":"Andreas Br\u00f8nden","orcid":"https://orcid.org/0000-0003-1262-3769","observed_orcids":["https://orcid.org/0000-0003-1262-3769"]},"institutions":[{"id":"https://openalex.org/I2802582725","display_name":"Gentofte Hospital","ror":"https://ror.org/051dzw862","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802582725"]},{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Andreas Br\u00f8nden","raw_affiliation_strings":["Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark","institution_ids":["https://openalex.org/I2802582725","https://openalex.org/I4405255865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071101758","display_name":"Lea N\u00f8rgaard Gustafsson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189090001","display_name":"Novo Nordisk (Denmark)","ror":"https://ror.org/0435rc536","country_code":"DK","type":"company","lineage":["https://openalex.org/I189090001","https://openalex.org/I2801134892","https://openalex.org/I4210159963"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Lea N. Gustafsson","raw_affiliation_strings":["Department of Biostatistics, Novo Nordisk A/S, Aalborg, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, Novo Nordisk A/S, Aalborg, Denmark","institution_ids":["https://openalex.org/I189090001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068479225","display_name":"David Peick Sonne","orcid":"https://orcid.org/0000-0002-4898-2256","observed_orcids":["https://orcid.org/0000-0002-4898-2256"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2801941904","display_name":"Bispebjerg Hospital","ror":"https://ror.org/00td68a17","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801941904","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802582725","display_name":"Gentofte Hospital","ror":"https://ror.org/051dzw862","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802582725"]},{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"David P. Sonne","raw_affiliation_strings":["Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark","Department of Clinical Pharmacology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark","institution_ids":["https://openalex.org/I2802582725","https://openalex.org/I4405255865"]},{"raw_affiliation_string":"Department of Clinical Pharmacology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2801941904"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075364098","display_name":"Louise Vedtofte","orcid":"https://orcid.org/0000-0003-0703-701X","observed_orcids":["https://orcid.org/0000-0003-0703-701X"]},"institutions":[{"id":"https://openalex.org/I2802582725","display_name":"Gentofte Hospital","ror":"https://ror.org/051dzw862","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802582725"]},{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Louise Vedtofte","raw_affiliation_strings":["Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark","institution_ids":["https://openalex.org/I2802582725","https://openalex.org/I4405255865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004120950","display_name":"Tina Vilsb\u00f8ll","orcid":"https://orcid.org/0000-0002-0456-6787","observed_orcids":["https://orcid.org/0000-0002-0456-6787"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2802582725","display_name":"Gentofte Hospital","ror":"https://ror.org/051dzw862","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802582725"]},{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Tina Vilsb\u00f8ll","raw_affiliation_strings":["Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark","Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark","institution_ids":["https://openalex.org/I2802582725","https://openalex.org/I4405255865"]},{"raw_affiliation_string":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079352451","display_name":"Filip Krag Knop","orcid":"https://orcid.org/0000-0002-2495-5034","observed_orcids":["https://orcid.org/0000-0002-2495-5034"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2802582725","display_name":"Gentofte Hospital","ror":"https://ror.org/051dzw862","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802582725"]},{"id":"https://openalex.org/I4391767703","display_name":"Novo Nordisk Foundation Center for Basic Metabolic Research","ror":"https://ror.org/02s32fb62","country_code":"DK","type":"other","lineage":["https://openalex.org/I124055696","https://openalex.org/I4391767703"]},{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":true,"raw_author_name":"Filip K. Knop","raw_affiliation_strings":["Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark","Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark","Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark"],"raw_orcid":"https://orcid.org/0000-0002-2495-5034","affiliations":[{"raw_affiliation_string":"Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark","institution_ids":["https://openalex.org/I2802582725","https://openalex.org/I4405255865"]},{"raw_affiliation_string":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I4391767703"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5079352451"],"corresponding_institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2802582725","https://openalex.org/I4391767703","https://openalex.org/I4405255865"],"apc_list":{"value":5380,"currency":"USD","value_usd":5380},"apc_paid":{"value":5380,"currency":"USD","value_usd":5380},"fwci":2.9169,"has_fulltext":true,"cited_by_count":54,"citation_normalized_percentile":{"value":0.9175136,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"20","issue":"11","first_page":"2557","last_page":"2564"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.367900013923645,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.367900013923645,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10518","display_name":"Gallbladder and Bile Duct Disorders","score":0.35030001401901245,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12539","display_name":"Pharmacology and Obesity Treatment","score":0.1826999932527542,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/liraglutide","display_name":"liraglutide","score":1.0},{"id":"https://openalex.org/keywords/gallbladder-emptying","display_name":"gallbladder emptying","score":0.9929999709129333},{"id":"https://openalex.org/keywords/gallbladder-ejection-fraction","display_name":"gallbladder ejection fraction","score":0.9879999756813049},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8920000195503235},{"id":"https://openalex.org/keywords/overweight","display_name":"overweight","score":0.9760000109672546},{"id":"https://openalex.org/keywords/glp-1-receptor-agonists","display_name":"GLP-1 receptor agonists","score":0.9470000267028809},{"id":"https://openalex.org/keywords/nausea","display_name":"nausea","score":0.5019999742507935},{"id":"https://openalex.org/keywords/constipation","display_name":"constipation","score":0.9909999966621399}],"concepts":[{"id":"https://openalex.org/C2781308992","wikidata":"https://www.wikidata.org/wiki/Q2526479","display_name":"Liraglutide","level":4,"score":0.9675738215446472},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8676239848136902},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.799842357635498},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5876660346984863},{"id":"https://openalex.org/C2780586474","wikidata":"https://www.wikidata.org/wiki/Q332428","display_name":"Overweight","level":3,"score":0.5839686393737793},{"id":"https://openalex.org/C2780580376","wikidata":"https://www.wikidata.org/wiki/Q186889","display_name":"Nausea","level":2,"score":0.5673219561576843},{"id":"https://openalex.org/C2778199505","wikidata":"https://www.wikidata.org/wiki/Q2992990","display_name":"Postprandial","level":3,"score":0.5227594375610352},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.47327446937561035},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.46099236607551575},{"id":"https://openalex.org/C3020479747","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Gastric emptying","level":3,"score":0.4586716592311859},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4362528324127197},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.42413944005966187},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.33831533789634705},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.23873403668403625},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.21033528447151184},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2047296166419983},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.1041637659072876},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.09561452269554138},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000069450","descriptor_name":"Liraglutide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000069450","descriptor_name":"Liraglutide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D010919","descriptor_name":"Placebos","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016473","descriptor_name":"Gallbladder Emptying","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D019518","descriptor_name":"Postprandial Period","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D050177","descriptor_name":"Overweight","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D050177","descriptor_name":"Overweight","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050177","descriptor_name":"Overweight","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1111/dom.13420","doi":"https://doi.org/10.1111/dom.13420","is_oa":true,"landing_page_url":"https://doi.org/10.1111/dom.13420","pdf_url":"https://www.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/dom.13420","source":{"id":"https://openalex.org/S148394532","display_name":"Diabetes Obesity and Metabolism","issn_l":"1462-8902","issn":["1462-8902","1463-1326"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, Obesity and Metabolism","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5177137","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6220792","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:29892986","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29892986","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, obesity & metabolism","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6220792","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6220792/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Obes Metab","raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:openaire/543672af-8336-407e-abdf-d33f898e5a25","doi":null,"is_oa":true,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/543672af-8336-407e-abdf-d33f898e5a25","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nexoe-Larsen, C C, Sorensen, P H, Hausner, H, Agersnap, M, Baekdal, M, Bronden, A, Gustafsson, L N, Sonne, D P, Vedtofte, L, Vilsboll, T & Knop, F K 2018, 'Effects of liraglutide on gallbladder emptying : A randomized, placebo-controlled trial in adults with overweight or obesity', Diabetes, Obesity and Metabolism, vol. 20, no. 11, pp. 2557-2564. https://doi.org/10.1111/dom.13420","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1111/dom.13420","doi":"https://doi.org/10.1111/dom.13420","is_oa":true,"landing_page_url":"https://doi.org/10.1111/dom.13420","pdf_url":"https://www.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/dom.13420","source":{"id":"https://openalex.org/S148394532","display_name":"Diabetes Obesity and Metabolism","issn_l":"1462-8902","issn":["1462-8902","1463-1326"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, Obesity and Metabolism","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[{"id":"https://openalex.org/G1630305306","display_name":null,"funder_award_id":"SDCC 3.F CMP","funder_id":"https://openalex.org/F4320318293","funder_display_name":"Steno Diabetes Center Copenhagen"},{"id":"https://openalex.org/G3300345539","display_name":null,"funder_award_id":"NNF11OC1014545","funder_id":"https://openalex.org/F4320325957","funder_display_name":"Novo Nordisk Fonden"}],"funders":[{"id":"https://openalex.org/F4320318293","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87"},{"id":"https://openalex.org/F4320322436","display_name":"Novo Nordisk","ror":"https://ror.org/0435rc536"},{"id":"https://openalex.org/F4320325957","display_name":"Novo Nordisk Fonden","ror":"https://ror.org/04txyc737"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2808065103.pdf","grobid_xml":"https://content.openalex.org/works/W2808065103.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W58254175","https://openalex.org/W134235633","https://openalex.org/W807162506","https://openalex.org/W1510097375","https://openalex.org/W1724200113","https://openalex.org/W1798757189","https://openalex.org/W1965431821","https://openalex.org/W1966262160","https://openalex.org/W1966500936","https://openalex.org/W1975756049","https://openalex.org/W1990187461","https://openalex.org/W2014959360","https://openalex.org/W2016732441","https://openalex.org/W2017316297","https://openalex.org/W2020464945","https://openalex.org/W2028637607","https://openalex.org/W2035014883","https://openalex.org/W2048290927","https://openalex.org/W2065444806","https://openalex.org/W2076070753","https://openalex.org/W2090467991","https://openalex.org/W2106036385","https://openalex.org/W2106459856","https://openalex.org/W2107479916","https://openalex.org/W2112264217","https://openalex.org/W2125464948","https://openalex.org/W2127782831","https://openalex.org/W2163229244","https://openalex.org/W2290082435","https://openalex.org/W2411054021","https://openalex.org/W2425644022","https://openalex.org/W2497721881","https://openalex.org/W2498502918","https://openalex.org/W2590664415","https://openalex.org/W2592954074","https://openalex.org/W2620232270","https://openalex.org/W2726799618","https://openalex.org/W2759588258"],"related_works":["https://openalex.org/W4241245094","https://openalex.org/W2607167595","https://openalex.org/W1979039986","https://openalex.org/W2759588258","https://openalex.org/W2607186909","https://openalex.org/W4320711737","https://openalex.org/W2028637607","https://openalex.org/W2606837046","https://openalex.org/W2606511851","https://openalex.org/W2498502918"],"abstract_inverted_index":{"Aims":[0],"Treatment":[1,245],"with":[2,9,32,39,73,80,211,219,246],"liraglutide":[3,26,29,58,187,212,229,247],"3.0":[4,30,78,188,213],"mg":[5,25,31,72,189,214],"has":[6],"been":[7],"associated":[8],"gallbladder\u2010related":[10],"adverse":[11,242],"events.":[12,243],"To":[13],"conduct":[14],"a":[15],"single\u2010centre,":[16],"double\u2010blind,":[17],"12\u2010week":[18,111,153],"trial":[19],"comparing":[20],"the":[21,99,110,126,168,172,226,238,251,258],"effect":[22],"of":[23],"0.6":[24,71],"and":[27,47,82,102,165,215,235],"steady\u2010state":[28],"placebo":[33,64,195],"on":[34],"gallbladder":[35,114],"emptying":[36],"in":[37,171],"adults":[38],"body":[40],"mass":[41],"index":[42],"(BMI)":[43],"\u226527":[44],"kg/m":[45,147],"2":[46,148],"without":[48],"diabetes.":[49],"Methods":[50],"Participants":[51],"were":[52,131,223,237],"randomized":[53],"1:1":[54],"to":[55,77,204,256,260],"once\u2010daily":[56],"subcutaneous":[57],"(":[59,65,190,196],"n":[60,66,191,197],"=":[61,67,192,198],"26)":[62],"or":[63],"26),":[68],"starting":[69,125],"at":[70,96],"0.6\u2010mg":[74,228],"weekly":[75],"increments":[76],"mg,":[79],"nutritional":[81],"physical":[83],"activity":[84],"counselling.":[85],"A":[86],"600\u2010kcal":[87],"(23.7":[88],"g":[89],"fat)":[90],"liquid":[91],"meal":[92],"test":[93],"was":[94,109,207],"performed":[95],"baseline,":[97],"after":[98,103,124,225],"first":[100,173,227],"dose":[101],"12":[104],"weeks.":[105],"The":[106,200],"primary":[107],"endpoint":[108],"maximum":[112],"postprandial":[113],"ejection":[115],"fraction":[116],"(GBEF":[117],"max":[118,155,206,253,262],"),":[119],"measured":[120],"over":[121],"240":[122],"minutes":[123,175,210,218],"meal.":[127],"Results":[128],"Baseline":[129],"characteristics":[130],"similar":[132],"between":[133],"groups":[134],"(mean":[135],"\u00b1":[136,141],"SD":[137],"overall":[138],"age":[139],"47.6":[140],"10.0":[142],"years,":[143],"BMI":[144],"32.6":[145],"\u00b13.4":[146],",":[149],"50%":[150],"women).":[151],"Mean":[152],"GBEF":[154,169,205,252,261],"(treatment":[156],"difference":[157],"\u22123.7%,":[158],"95%":[159,179],"confidence":[160],"interval":[161],"[CI]":[162],"\u221213.1,":[163],"5.7)":[164],"area":[166],"under":[167],"curve":[170],"60":[174],"(\u2212390%":[176],"\u00d7":[177],"min,":[178],"CI":[180],"\u2212919,":[181],"140)":[182],"did":[183,248],"not":[184,249],"differ":[185],"for":[186],"23)":[193],"vs":[194],"24).":[199],"median":[201],"(range)":[202],"time":[203,259],"151":[208],"(11\u2010240)":[209],"77":[216],"(22\u2010212)":[217],"placebo.":[220],"Similar":[221],"findings":[222],"noted":[224],"dose.":[230],"Gastrointestinal":[231],"disorders,":[232],"notably":[233],"nausea":[234],"constipation,":[236],"most":[239],"frequently":[240],"reported":[241],"Conclusions":[244],"affect":[250],"but":[254],"appeared":[255],"prolong":[257],".":[263]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2018-06-21T00:00:00"}