{"id":"https://openalex.org/W2807780965","doi":"https://doi.org/10.1007/978-1-4939-7902-8_9","title":"Thyroid Hormones and Derivatives: Endogenous Thyroid Hormones and Their Targets","display_name":"Thyroid Hormones and Derivatives: Endogenous Thyroid Hormones and Their Targets","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2807780965","doi":"https://doi.org/10.1007/978-1-4939-7902-8_9","mag":"2807780965","pmid":"https://pubmed.ncbi.nlm.nih.gov/29892819"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4939-7902-8_9","doi":"https://doi.org/10.1007/978-1-4939-7902-8_9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4939-7902-8_9","pdf_url":null,"source":{"id":"https://openalex.org/S4210172139","display_name":"Methods in molecular biology","issn_l":"1064-3745","issn":["1064-3745","1940-6029"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Molecular Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4244940080","display_name":"Thyroid Hormone Nuclear Receptor"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052536282","display_name":"Josef K\u00f6hrle","orcid":"https://orcid.org/0000-0002-9187-9078","observed_orcids":["https://orcid.org/0000-0002-9187-9078"]},"institutions":[{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Josef K\u00f6hrle","raw_affiliation_strings":["Charit\u00e9-Universit\u00e4tsmedizin Berlin, Charit\u00e9 - Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zuBerlin, and Berlin Institute of Health, Institut f\u00fcr Experimentelle Endokrinologie, Berlin, Germany. josef.koehrle@charite.de","Charit\u00e9-Universit\u00e4tsmedizin Berlin, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zuBerlin, and Berlin Institute of Health, Institut f\u00fcr Experimentelle Endokrinologie, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Charit\u00e9-Universit\u00e4tsmedizin Berlin, Charit\u00e9 - Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zuBerlin, and Berlin Institute of Health, Institut f\u00fcr Experimentelle Endokrinologie, Berlin, Germany. josef.koehrle@charite.de","institution_ids":["https://openalex.org/I7877124"]},{"raw_affiliation_string":"Charit\u00e9-Universit\u00e4tsmedizin Berlin, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zuBerlin, and Berlin Institute of Health, Institut f\u00fcr Experimentelle Endokrinologie, Berlin, Germany","institution_ids":["https://openalex.org/I75951250","https://openalex.org/I7877124"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5052536282"],"corresponding_institution_ids":["https://openalex.org/I75951250","https://openalex.org/I7877124"],"apc_list":null,"apc_paid":null,"fwci":22.7331,"has_fulltext":false,"cited_by_count":53,"citation_normalized_percentile":{"value":0.99687779,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"1801","issue":null,"first_page":"85","last_page":"104"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13563","display_name":"Chemical Analysis and Environmental Impact","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thyroid-hormones","display_name":"thyroid hormones","score":0.9860000014305115},{"id":"https://openalex.org/keywords/thyroid-hormone-metabolites","display_name":"thyroid hormone metabolites","score":0.9309999942779541},{"id":"https://openalex.org/keywords/thyroxine","display_name":"thyroxine","score":0.7960000038146973},{"id":"https://openalex.org/keywords/triiodothyronine","display_name":"triiodothyronine","score":0.9750000238418579},{"id":"https://openalex.org/keywords/reverse-t3","display_name":"reverse T3","score":0.9929999709129333},{"id":"https://openalex.org/keywords/thyronamines","display_name":"thyronamines","score":0.8989999890327454},{"id":"https://openalex.org/keywords/thyroid-hormone-binding-proteins","display_name":"thyroid hormone binding proteins","score":0.6610000133514404},{"id":"https://openalex.org/keywords/thyroxine-binding-globulin","display_name":"thyroxine-binding globulin","score":0.8040000200271606},{"id":"https://openalex.org/keywords/prealbumin","display_name":"prealbumin","score":0.9380000233650208},{"id":"https://openalex.org/keywords/apolipoprotein-b-100","display_name":"apolipoprotein B-100","score":0.8569999933242798},{"id":"https://openalex.org/keywords/thyroid-hormone-transporters","display_name":"thyroid hormone transporters","score":0.796999990940094},{"id":"https://openalex.org/keywords/mct8","display_name":"MCT8","score":0.8709999918937683},{"id":"https://openalex.org/keywords/mct10","display_name":"MCT10","score":0.8740000128746033},{"id":"https://openalex.org/keywords/organic-anion-transporting-polypeptides","display_name":"organic anion transporting polypeptides","score":0.8519999980926514},{"id":"https://openalex.org/keywords/lat","display_name":"LAT","score":0.6510000228881836},{"id":"https://openalex.org/keywords/thyroid-hormone-receptor","display_name":"thyroid hormone receptor","score":0.8970000147819519},{"id":"https://openalex.org/keywords/deiodinases","display_name":"deiodinases","score":0.878000020980835},{"id":"https://openalex.org/keywords/sulfation","display_name":"sulfation","score":0.7509999871253967},{"id":"https://openalex.org/keywords/glucuronidation","display_name":"glucuronidation","score":0.9980000257492065},{"id":"https://openalex.org/keywords/hormone-metabolism","display_name":"hormone metabolism","score":0.45500001311302185}],"concepts":[{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.8491639494895935},{"id":"https://openalex.org/C2779571634","wikidata":"https://www.wikidata.org/wiki/Q422106","display_name":"Thyroid hormones","level":3,"score":0.7802180051803589},{"id":"https://openalex.org/C16613235","wikidata":"https://www.wikidata.org/wiki/Q285982","display_name":"Endogeny","level":2,"score":0.6779318451881409},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.6738476157188416},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6034072637557983},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.535932719707489},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3748742938041687}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007118","descriptor_name":"Immunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007453","descriptor_name":"Iodide Peroxidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011988","descriptor_name":"Receptors, Thyroid Hormone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013963","descriptor_name":"Thyroid Hormones","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013963","descriptor_name":"Thyroid Hormones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013963","descriptor_name":"Thyroid Hormones","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013970","descriptor_name":"Thyronines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-1-4939-7902-8_9","doi":"https://doi.org/10.1007/978-1-4939-7902-8_9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4939-7902-8_9","pdf_url":null,"source":{"id":"https://openalex.org/S4210172139","display_name":"Methods in molecular biology","issn_l":"1064-3745","issn":["1064-3745","1940-6029"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Molecular Biology","raw_type":"book-chapter"},{"id":"pmid:29892819","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29892819","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in molecular biology (Clifton, N.J.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":126,"referenced_works":["https://openalex.org/W292112127","https://openalex.org/W332128574","https://openalex.org/W871922482","https://openalex.org/W1479716699","https://openalex.org/W1541420706","https://openalex.org/W1553329582","https://openalex.org/W1594076929","https://openalex.org/W1602307529","https://openalex.org/W1607005508","https://openalex.org/W1766142764","https://openalex.org/W1808165721","https://openalex.org/W1892040734","https://openalex.org/W1925071458","https://openalex.org/W1936573764","https://openalex.org/W1971005406","https://openalex.org/W1976880940","https://openalex.org/W1977631945","https://openalex.org/W1977986304","https://openalex.org/W1986145451","https://openalex.org/W1987580591","https://openalex.org/W1990269165","https://openalex.org/W1990675136","https://openalex.org/W1990696145","https://openalex.org/W1991913878","https://openalex.org/W1992735251","https://openalex.org/W1995676967","https://openalex.org/W1997598284","https://openalex.org/W1999179446","https://openalex.org/W1999610793","https://openalex.org/W2008259325","https://openalex.org/W2009634931","https://openalex.org/W2015150329","https://openalex.org/W2015758792","https://openalex.org/W2037677271","https://openalex.org/W2045559876","https://openalex.org/W2045989767","https://openalex.org/W2047289730","https://openalex.org/W2047308744","https://openalex.org/W2054438162","https://openalex.org/W2056664245","https://openalex.org/W2057712172","https://openalex.org/W2058525638","https://openalex.org/W2062166454","https://openalex.org/W2062594762","https://openalex.org/W2063068406","https://openalex.org/W2067353542","https://openalex.org/W2069646124","https://openalex.org/W2071408780","https://openalex.org/W2073915823","https://openalex.org/W2077715471","https://openalex.org/W2086596578","https://openalex.org/W2086734156","https://openalex.org/W2091422735","https://openalex.org/W2092795070","https://openalex.org/W2095253816","https://openalex.org/W2110647490","https://openalex.org/W2116353330","https://openalex.org/W2122982900","https://openalex.org/W2130569250","https://openalex.org/W2130638571","https://openalex.org/W2136133737","https://openalex.org/W2142938005","https://openalex.org/W2150335827","https://openalex.org/W2152462131","https://openalex.org/W2152498124","https://openalex.org/W2160079487","https://openalex.org/W2162358004","https://openalex.org/W2162959038","https://openalex.org/W2166082696","https://openalex.org/W2168613183","https://openalex.org/W2173065406","https://openalex.org/W2175734827","https://openalex.org/W2175937775","https://openalex.org/W2186261794","https://openalex.org/W2266922729","https://openalex.org/W2268016365","https://openalex.org/W2282233091","https://openalex.org/W2286191259","https://openalex.org/W2318017892","https://openalex.org/W2328618770","https://openalex.org/W2334962192","https://openalex.org/W2347201063","https://openalex.org/W2385280152","https://openalex.org/W2395757999","https://openalex.org/W2395950874","https://openalex.org/W2395968852","https://openalex.org/W2397273336","https://openalex.org/W2405756312","https://openalex.org/W2429730573","https://openalex.org/W2471050545","https://openalex.org/W2513683667","https://openalex.org/W2523933674","https://openalex.org/W2528971420","https://openalex.org/W2531703351","https://openalex.org/W2537461889","https://openalex.org/W2550684835","https://openalex.org/W2553575456","https://openalex.org/W2558905392","https://openalex.org/W2560893596","https://openalex.org/W2563638624","https://openalex.org/W2566552250","https://openalex.org/W2567054134","https://openalex.org/W2570527704","https://openalex.org/W2570738281","https://openalex.org/W2578897403","https://openalex.org/W2582644191","https://openalex.org/W2585303886","https://openalex.org/W2585869774","https://openalex.org/W2586134824","https://openalex.org/W2590819044","https://openalex.org/W2592698726","https://openalex.org/W2593889687","https://openalex.org/W2594446183","https://openalex.org/W2598956467","https://openalex.org/W2601763448","https://openalex.org/W2605706824","https://openalex.org/W2607029183","https://openalex.org/W2616869817","https://openalex.org/W2617455138","https://openalex.org/W2618178072","https://openalex.org/W2738313665","https://openalex.org/W2748125750","https://openalex.org/W2748327758","https://openalex.org/W2748821656","https://openalex.org/W3156303907","https://openalex.org/W4241291456"],"related_works":["https://openalex.org/W2946272758","https://openalex.org/W2074532062","https://openalex.org/W4409046210","https://openalex.org/W2397273336","https://openalex.org/W1976761835","https://openalex.org/W2481763966","https://openalex.org/W2400170620","https://openalex.org/W299965315","https://openalex.org/W2908558765","https://openalex.org/W2009996442"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":11}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-06-21T00:00:00"}