{"id":"https://openalex.org/W2807771978","doi":"https://doi.org/10.1371/journal.pone.0199028","title":"QTc interval prolongation in critically ill patients: Prevalence, risk factors and associated medications","display_name":"QTc interval prolongation in critically ill patients: Prevalence, risk factors and associated medications","publication_year":2018,"publication_date":"2018-06-13","ids":{"openalex":"https://openalex.org/W2807771978","doi":"https://doi.org/10.1371/journal.pone.0199028","mag":"2807771978","pmid":"https://pubmed.ncbi.nlm.nih.gov/29898002","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5999273"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0199028","doi":"https://doi.org/10.1371/journal.pone.0199028","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0199028","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0199028&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0199028&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089881045","display_name":"Fl\u00e1via Evelyn Medeiros Fernandes","orcid":"https://orcid.org/0000-0001-6017-9944","observed_orcids":["https://orcid.org/0000-0001-6017-9944"]},"institutions":[{"id":"https://openalex.org/I35046152","display_name":"Universidade Federal do Rio Grande do Norte","ror":"https://ror.org/04wn09761","country_code":"BR","type":"education","lineage":["https://openalex.org/I35046152"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Fl\u00e1via Medeiros Fernandes","raw_affiliation_strings":["Integrated Multiprofessional Health Residency Program-Adult Intensive Care Unit, Pharmacy Department, Health Sciences Centre, Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil"],"raw_orcid":"https://orcid.org/0000-0001-6017-9944","affiliations":[{"raw_affiliation_string":"Integrated Multiprofessional Health Residency Program-Adult Intensive Care Unit, Pharmacy Department, Health Sciences Centre, Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil","institution_ids":["https://openalex.org/I35046152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001507513","display_name":"Eliane Pereira da Silva","orcid":"https://orcid.org/0000-0002-3364-5046","observed_orcids":["https://orcid.org/0000-0002-3364-5046"]},"institutions":[{"id":"https://openalex.org/I35046152","display_name":"Universidade Federal do Rio Grande do Norte","ror":"https://ror.org/04wn09761","country_code":"BR","type":"education","lineage":["https://openalex.org/I35046152"]},{"id":"https://openalex.org/I4210094979","display_name":"Hospital Universit\u00e1rio Onofre Lopes","ror":"https://ror.org/00mmnz357","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210094979"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Eliane Pereira Silva","raw_affiliation_strings":["University Hospital Onofre Lopes, Health Sciences Centre, Universidade Federal do Rio Grande Norte, Natal, RN, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital Onofre Lopes, Health Sciences Centre, Universidade Federal do Rio Grande Norte, Natal, RN, Brazil","institution_ids":["https://openalex.org/I35046152","https://openalex.org/I4210094979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032581021","display_name":"Rand Randall Martins","orcid":"https://orcid.org/0000-0001-9668-0482","observed_orcids":["https://orcid.org/0000-0001-9668-0482"]},"institutions":[{"id":"https://openalex.org/I35046152","display_name":"Universidade Federal do Rio Grande do Norte","ror":"https://ror.org/04wn09761","country_code":"BR","type":"education","lineage":["https://openalex.org/I35046152"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Rand Randall Martins","raw_affiliation_strings":["Pharmacy Department, Health Sciences Centre, Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacy Department, Health Sciences Centre, Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil","institution_ids":["https://openalex.org/I35046152"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101865685","display_name":"Ant\u00f3nio Gouveia Oliveira","orcid":"https://orcid.org/0000-0001-9103-6532","observed_orcids":["https://orcid.org/0000-0001-9103-6532"]},"institutions":[{"id":"https://openalex.org/I35046152","display_name":"Universidade Federal do Rio Grande do Norte","ror":"https://ror.org/04wn09761","country_code":"BR","type":"education","lineage":["https://openalex.org/I35046152"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Antonio Gouveia Oliveira","raw_affiliation_strings":["Pharmacy Department, Health Sciences Centre, Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacy Department, Health Sciences Centre, Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil","institution_ids":["https://openalex.org/I35046152"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5089881045"],"corresponding_institution_ids":["https://openalex.org/I35046152"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":5.4732,"has_fulltext":true,"cited_by_count":62,"citation_normalized_percentile":{"value":0.96824485,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"13","issue":"6","first_page":"e0199028","last_page":"e0199028"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10496","display_name":"Pharmaceutical Practices and Patient Outcomes","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acquired-long-qt-syndrome","display_name":"acquired long QT syndrome","score":0.8429999947547913},{"id":"https://openalex.org/keywords/qtc-prolongation","display_name":"QTc prolongation","score":0.8790000081062317},{"id":"https://openalex.org/keywords/critically-ill-patients","display_name":"critically ill patients","score":0.9049999713897705},{"id":"https://openalex.org/keywords/intensive-care-unit-admission","display_name":"intensive care unit admission","score":0.8939999938011169},{"id":"https://openalex.org/keywords/haloperidol","display_name":"haloperidol","score":0.8379999995231628},{"id":"https://openalex.org/keywords/amiodarone","display_name":"amiodarone","score":1.0},{"id":"https://openalex.org/keywords/furosemide","display_name":"furosemide","score":0.9909999966621399},{"id":"https://openalex.org/keywords/clopidogrel","display_name":"clopidogrel","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bradycardia","display_name":"bradycardia","score":0.9959999918937683},{"id":"https://openalex.org/keywords/charlson-comorbidity-index","display_name":"Charlson Comorbidity Index","score":0.9929999709129333},{"id":"https://openalex.org/keywords/prevalence","display_name":"prevalence","score":0.6010000109672546},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.9879999756813049}],"concepts":[{"id":"https://openalex.org/C118441451","wikidata":"https://www.wikidata.org/wiki/Q12074763","display_name":"QT interval","level":2,"score":0.6999430656433105},{"id":"https://openalex.org/C2991859549","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Critically ill","level":2,"score":0.6771479845046997},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6658023595809937},{"id":"https://openalex.org/C2777672339","wikidata":"https://www.wikidata.org/wiki/Q7249641","display_name":"Prolongation","level":2,"score":0.6178920865058899},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.42064422369003296},{"id":"https://openalex.org/C2779703243","wikidata":"https://www.wikidata.org/wiki/Q653924","display_name":"Long QT syndrome","level":3,"score":0.4180114269256592},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39747995138168335}],"mesh":[{"descriptor_ui":"D000077144","descriptor_name":"Clopidogrel","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000077144","descriptor_name":"Clopidogrel","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000638","descriptor_name":"Amiodarone","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000638","descriptor_name":"Amiodarone","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005665","descriptor_name":"Furosemide","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D005665","descriptor_name":"Furosemide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006220","descriptor_name":"Haloperidol","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D006220","descriptor_name":"Haloperidol","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007362","descriptor_name":"Intensive Care Units","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008133","descriptor_name":"Long QT Syndrome","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D008133","descriptor_name":"Long QT Syndrome","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D008133","descriptor_name":"Long QT Syndrome","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016017","descriptor_name":"Odds Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016638","descriptor_name":"Critical Illness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1371/journal.pone.0199028","doi":"https://doi.org/10.1371/journal.pone.0199028","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0199028","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0199028&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4963016","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5999273","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5999273","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5999273","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmid:29898002","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29898002","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:RePEc:plo:pone00:0199028","doi":null,"is_oa":false,"landing_page_url":"https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199028","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:bc54a3f23ee94437a6f626bc5e8526c2","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/bc54a3f23ee94437a6f626bc5e8526c2","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 13, Iss 6, p e0199028 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0199028","doi":"https://doi.org/10.1371/journal.pone.0199028","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0199028","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0199028&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2807771978.pdf","grobid_xml":"https://content.openalex.org/works/W2807771978.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W897308740","https://openalex.org/W1576812268","https://openalex.org/W1596681198","https://openalex.org/W1963537950","https://openalex.org/W1965135485","https://openalex.org/W1981644786","https://openalex.org/W1983951532","https://openalex.org/W1987966366","https://openalex.org/W2005104410","https://openalex.org/W2026919044","https://openalex.org/W2031528378","https://openalex.org/W2051241891","https://openalex.org/W2060105258","https://openalex.org/W2082072065","https://openalex.org/W2086112671","https://openalex.org/W2086879878","https://openalex.org/W2089214448","https://openalex.org/W2100004795","https://openalex.org/W2104050703","https://openalex.org/W2105693632","https://openalex.org/W2120346674","https://openalex.org/W2133921028","https://openalex.org/W2147132879","https://openalex.org/W2154025234","https://openalex.org/W2154785099","https://openalex.org/W2164958041","https://openalex.org/W2168618342","https://openalex.org/W2235145344","https://openalex.org/W2235248696","https://openalex.org/W2265693929","https://openalex.org/W2322526196","https://openalex.org/W2332482256","https://openalex.org/W2334052098","https://openalex.org/W2435493985","https://openalex.org/W2530198916","https://openalex.org/W2530419171","https://openalex.org/W2542824823","https://openalex.org/W2555834695"],"related_works":["https://openalex.org/W2768972380","https://openalex.org/W201540358","https://openalex.org/W105975982","https://openalex.org/W1575472445","https://openalex.org/W2105693632","https://openalex.org/W3165456693","https://openalex.org/W2790275782","https://openalex.org/W2086879878","https://openalex.org/W4415799338","https://openalex.org/W2062264779"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"investigate":[2],"the":[3,26,41,58,74,121],"prevalence":[4,107],"and":[5,23,48,86,137,154,192],"risk":[6,27,144],"factors":[7,145],"of":[8,28,60],"acquired":[9],"long":[10],"QT":[11,71],"syndrome":[12],"(LQTS)":[13],"on":[14,73],"admission":[15,75,98,127],"to":[16,24,57,125],"a":[17,61,70],"general":[18],"Intensive":[19],"Care":[20],"Unit":[21],"(ICU),":[22],"assess":[25],"LQTS":[29,66,106,111,176],"associated":[30,159],"with":[31,160,189,194,199],"prescribed":[32,119],"medications.":[33],"METHODS:":[34],"Prospective":[35],"observational,":[36],"cross-sectional":[37],"study":[38],"approved":[39],"by":[40],"Institutional":[42],"Review":[43],"Board.":[44],"Between":[45],"May":[46],"2014":[47],"July":[49],"2016,":[50],"412":[51],"patients":[52,132,185,193],">18":[53],"years-old":[54],"consecutively":[55],"admitted":[56,188],"ICU":[59,126,184],"university":[62],"hospital":[63],"were":[64,99,158],"included.":[65],"was":[67,103,108],"defined":[68],"as":[69,162,164],"interval":[72],"electrocardiogram":[76],"corrected":[77],"using":[78],"Bazett's":[79],"formula":[80],"(QTc)":[81],">460":[82],"ms":[83,88],"for":[84,89,146,207],"men":[85],">470":[87],"women.":[90],"All":[91],"medications":[92],"administered":[93],"within":[94],"24":[95,122],"hours":[96,123],"before":[97],"recorded.":[100],"Logistic":[101],"regression":[102],"used.":[104],"RESULTS:":[105],"27.9%.":[109],"In":[110],"patients,":[112,183],"70.4%":[113,129],"had":[114],"\u2265":[115],"1":[116],"LQTS-inducing":[117,190],"drug":[118,166],"in":[120,130,180],"prior":[124],"versus":[128],"non-LQTS":[131],"(p":[133],"=":[134],"0.99).":[135],"Bradycardia":[136],"Charlson":[138,201],"morbidity":[139],"index":[140,203],"score":[141],"are":[142,186],"independent":[143],"LQTS.":[147,208],"Haloperidol":[148],"(OR":[149,152,156,172],"4.416),":[150],"amiodarone":[151],"2.509)":[153],"furosemide":[155],"1.895)":[157],"LQTS,":[161],"well":[163],"another":[165],"not":[167],"yet":[168],"described,":[169],"namely":[170],"clopidogrel":[171],"2.241).":[173],"CONCLUSIONS:":[174],"The":[175],"is":[177],"highly":[178],"prevalent":[179],"critically":[181],"ill":[182],"often":[187],"medications,":[191],"slow":[195],"heart":[196],"rate":[197],"or":[198],"high":[200],"comorbidity":[202],"should":[204],"be":[205],"evaluated":[206]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-06-21T00:00:00"}