{"id":"https://openalex.org/W2807744518","doi":"https://doi.org/10.21037/ncri.2018.06.01","title":"New rules for regulation of genes by piRNAs in C. elegans","display_name":"New rules for regulation of genes by piRNAs in C. elegans","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2807744518","doi":"https://doi.org/10.21037/ncri.2018.06.01","mag":"2807744518"},"language":"en","primary_location":{"id":"doi:10.21037/ncri.2018.06.01","doi":"https://doi.org/10.21037/ncri.2018.06.01","is_oa":true,"landing_page_url":"https://doi.org/10.21037/ncri.2018.06.01","pdf_url":null,"source":{"id":"https://openalex.org/S4210194965","display_name":"Non-coding RNA Investigation","issn_l":"2522-6673","issn":["2522-6673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Non-coding RNA Investigation","raw_type":"journal-article"},"volume":null,"type":"editorial","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.21037/ncri.2018.06.01","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089277246","display_name":"Christophe Antoniewski","orcid":"https://orcid.org/0000-0001-7709-2116","observed_orcids":["https://orcid.org/0000-0001-7709-2116"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210107326","display_name":"Institut de Biologie Paris-Seine","ror":"https://ror.org/01c2cjg59","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210107326"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Christophe Antoniewski","raw_affiliation_strings":["Drosophila Genetics and Epigenetics, Sorbonne Universit\u00e9, CNRS, Biologie du D\u00e9veloppement - Institut de Biologie Paris Seine, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drosophila Genetics and Epigenetics, Sorbonne Universit\u00e9, CNRS, Biologie du D\u00e9veloppement - Institut de Biologie Paris Seine, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I39804081","https://openalex.org/I4210107326"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041164066","display_name":"Cl\u00e9ment Carr\u00e9","orcid":"https://orcid.org/0000-0002-9668-4288","observed_orcids":["https://orcid.org/0000-0002-9668-4288"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210107326","display_name":"Institut de Biologie Paris-Seine","ror":"https://ror.org/01c2cjg59","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210107326"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Cl\u00e9ment Carr\u00e9","raw_affiliation_strings":["Drosophila Genetics and Epigenetics, Sorbonne Universit\u00e9, CNRS, Biologie du D\u00e9veloppement - Institut de Biologie Paris Seine, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drosophila Genetics and Epigenetics, Sorbonne Universit\u00e9, CNRS, Biologie du D\u00e9veloppement - Institut de Biologie Paris Seine, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I39804081","https://openalex.org/I4210107326"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5041164066","https://openalex.org/A5089277246"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I39804081","https://openalex.org/I4210107326"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"2","issue":null,"first_page":"33","last_page":"33"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/piwi-interacting-rnas","display_name":"piRNA","score":0.8970000147819519},{"id":"https://openalex.org/keywords/transposable-elements","display_name":"transposable elements","score":0.7360000014305115},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.8230000138282776},{"id":"https://openalex.org/keywords/caenorhabditis-elegans","display_name":"Caenorhabditis elegans","score":0.9700000286102295},{"id":"https://openalex.org/keywords/transposon-insertion","display_name":"transposon insertion","score":0.6169999837875366},{"id":"https://openalex.org/keywords/genomic-instability","display_name":"genomic instability","score":0.7670000195503235},{"id":"https://openalex.org/keywords/genome-plasticity","display_name":"genome plasticity","score":0.7179999947547913},{"id":"https://openalex.org/keywords/evolution","display_name":"evolution","score":0.3100000023841858},{"id":"https://openalex.org/keywords/transcriptional-regulatory-networks","display_name":"transcriptional regulatory networks","score":0.7049999833106995}],"concepts":[{"id":"https://openalex.org/C4918238","wikidata":"https://www.wikidata.org/wiki/Q121438","display_name":"Transposable element","level":4,"score":0.8894850611686707},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.7713148593902588},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7123582363128662},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.6352239847183228},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5875375270843506},{"id":"https://openalex.org/C178169997","wikidata":"https://www.wikidata.org/wiki/Q2892636","display_name":"Genome instability","level":4,"score":0.5330912470817566},{"id":"https://openalex.org/C139807058","wikidata":"https://www.wikidata.org/wiki/Q352374","display_name":"Adaptation (eye)","level":2,"score":0.49288320541381836},{"id":"https://openalex.org/C2910146623","wikidata":"https://www.wikidata.org/wiki/Q121438","display_name":"DNA Transposable Elements","level":5,"score":0.46081772446632385},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4505154490470886},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.4237223267555237},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.23269373178482056},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.18133214116096497},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.08643516898155212},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.21037/ncri.2018.06.01","doi":"https://doi.org/10.21037/ncri.2018.06.01","is_oa":true,"landing_page_url":"https://doi.org/10.21037/ncri.2018.06.01","pdf_url":null,"source":{"id":"https://openalex.org/S4210194965","display_name":"Non-coding RNA Investigation","issn_l":"2522-6673","issn":["2522-6673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Non-coding RNA Investigation","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.21037/ncri.2018.06.01","doi":"https://doi.org/10.21037/ncri.2018.06.01","is_oa":true,"landing_page_url":"https://doi.org/10.21037/ncri.2018.06.01","pdf_url":null,"source":{"id":"https://openalex.org/S4210194965","display_name":"Non-coding RNA Investigation","issn_l":"2522-6673","issn":["2522-6673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Non-coding RNA Investigation","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W307470220","https://openalex.org/W1976342457","https://openalex.org/W2009644747","https://openalex.org/W2032640887","https://openalex.org/W2040816572","https://openalex.org/W2062288798","https://openalex.org/W2089441618","https://openalex.org/W2100336754","https://openalex.org/W2107333779","https://openalex.org/W2120686657","https://openalex.org/W2154222068","https://openalex.org/W2162674813","https://openalex.org/W2213777869","https://openalex.org/W2469085018","https://openalex.org/W2585690051","https://openalex.org/W2787112631","https://openalex.org/W2787719063","https://openalex.org/W2788865254","https://openalex.org/W2795496263","https://openalex.org/W2801961972"],"related_works":["https://openalex.org/W2345484738","https://openalex.org/W2939680127","https://openalex.org/W2556763090","https://openalex.org/W2544598565","https://openalex.org/W3188379277","https://openalex.org/W3005162899","https://openalex.org/W3131064259","https://openalex.org/W2775493833","https://openalex.org/W7095524358","https://openalex.org/W2768062840"],"abstract_inverted_index":{"Transposable":[0],"element":[1],"(TE)":[2],"insertions":[3],"create":[4],"new":[5,10],"gene":[6,11],"regulatory":[7,44],"elements":[8],"or":[9],"products,":[12],"thus":[13],"representing":[14],"a":[15],"major":[16],"driver":[17],"for":[18],"the":[19],"evolutionary":[20],"adaptation":[21],"and":[22,41],"genome":[23],"plasticity":[24],"of":[25,30],"organisms":[26],"(1).":[27],"However,":[28],"integration":[29],"TEs":[31],"can":[32],"also":[33],"provoke":[34],"genomic":[35],"instability":[36],"by":[37],"disrupting":[38],"protein-coding":[39],"genes":[40],"alter":[42],"transcriptional":[43],"networks.":[45]},"counts_by_year":[{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-06-21T00:00:00"}