{"id":"https://openalex.org/W2807358784","doi":"https://doi.org/10.1038/s41598-018-24238-w","title":"Controlling Indomethacin Release through Vapor-Phase Deposited Hydrogel Films by Adjusting the Cross-linker Density","display_name":"Controlling Indomethacin Release through Vapor-Phase Deposited Hydrogel Films by Adjusting the Cross-linker Density","publication_year":2018,"publication_date":"2018-05-01","ids":{"openalex":"https://openalex.org/W2807358784","doi":"https://doi.org/10.1038/s41598-018-24238-w","mag":"2807358784","pmid":"https://pubmed.ncbi.nlm.nih.gov/29739950","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5940858"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-018-24238-w","doi":"https://doi.org/10.1038/s41598-018-24238-w","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-24238-w","pdf_url":"https://www.nature.com/articles/s41598-018-24238-w.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-018-24238-w.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Paul Christian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4092182","display_name":"Graz University of Technology","ror":"https://ror.org/00d7xrm67","country_code":"AT","type":"education","lineage":["https://openalex.org/I4092182"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Paul Christian","raw_affiliation_strings":["Institute for Solid State Physics, NAWI Graz, Graz University of Technology, 8010, Graz, Austria. paul.christian@tugraz.at","Institute for Solid State Physics, NAWI Graz, Graz University of Technology, 8010, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Solid State Physics, NAWI Graz, Graz University of Technology, 8010, Graz, Austria. paul.christian@tugraz.at","institution_ids":["https://openalex.org/I4092182","https://openalex.org/I4210108044"]},{"raw_affiliation_string":"Institute for Solid State Physics, NAWI Graz, Graz University of Technology, 8010, Graz, Austria","institution_ids":["https://openalex.org/I4092182","https://openalex.org/I4210108044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035754626","display_name":"Stephan Tumphart","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4092182","display_name":"Graz University of Technology","ror":"https://ror.org/00d7xrm67","country_code":"AT","type":"education","lineage":["https://openalex.org/I4092182"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Stephan Tumphart","raw_affiliation_strings":["Institute for Solid State Physics, NAWI Graz, Graz University of Technology, 8010, Graz, Austria","Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology, University of Graz, 8010, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Solid State Physics, NAWI Graz, Graz University of Technology, 8010, Graz, Austria","institution_ids":["https://openalex.org/I4092182","https://openalex.org/I4210108044"]},{"raw_affiliation_string":"Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology, University of Graz, 8010, Graz, Austria","institution_ids":["https://openalex.org/I15766117"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024152386","display_name":"Heike M. A. Ehmann","orcid":"https://orcid.org/0000-0002-2680-1733","observed_orcids":["https://orcid.org/0000-0002-2680-1733"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Heike M. A. Ehmann","raw_affiliation_strings":["Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology, University of Graz, 8010, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology, University of Graz, 8010, Graz, Austria","institution_ids":["https://openalex.org/I15766117"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hans Riegler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Hans Riegler","raw_affiliation_strings":["Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology, University of Graz, 8010, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology, University of Graz, 8010, Graz, Austria","institution_ids":["https://openalex.org/I15766117"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066072184","display_name":"Anna Maria Coclite","orcid":"https://orcid.org/0000-0001-5562-9744","observed_orcids":["https://orcid.org/0000-0001-5562-9744"]},"institutions":[{"id":"https://openalex.org/I4092182","display_name":"Graz University of Technology","ror":"https://ror.org/00d7xrm67","country_code":"AT","type":"education","lineage":["https://openalex.org/I4092182"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Anna Maria Coclite","raw_affiliation_strings":["Institute for Solid State Physics, NAWI Graz, Graz University of Technology, 8010, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Solid State Physics, NAWI Graz, Graz University of Technology, 8010, Graz, Austria","institution_ids":["https://openalex.org/I4092182","https://openalex.org/I4210108044"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015337472","display_name":"Oliver Werzer","orcid":"https://orcid.org/0000-0003-0732-4422","observed_orcids":["https://orcid.org/0000-0003-0732-4422"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Oliver Werzer","raw_affiliation_strings":["Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology, University of Graz, 8010, Graz, Austria. oliver.werzer@uni-graz.at","Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology, University of Graz, 8010, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology, University of Graz, 8010, Graz, Austria. oliver.werzer@uni-graz.at","institution_ids":["https://openalex.org/I15766117"]},{"raw_affiliation_string":"Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology, University of Graz, 8010, Graz, Austria","institution_ids":["https://openalex.org/I15766117"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5015337472"],"corresponding_institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4092182","https://openalex.org/I4210108044"],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":1.1845,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":{"value":0.71760932,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"8","issue":"1","first_page":"7134","last_page":"7134"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.8984000086784363,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.8984000086784363,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.08969999849796295,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12642","display_name":"Polymer-Based Agricultural Enhancements","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/1102","display_name":"Agronomy and Crop Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/indomethacin","display_name":"indomethacin","score":0.9890000224113464},{"id":"https://openalex.org/keywords/controlled-drug-release","display_name":"controlled drug release","score":0.800000011920929},{"id":"https://openalex.org/keywords/initiated-chemical-vapor-deposition","display_name":"initiated chemical vapor deposition","score":0.8899999856948853},{"id":"https://openalex.org/keywords/hydrogel-films","display_name":"hydrogel films","score":0.7319999933242798},{"id":"https://openalex.org/keywords/2-hydroxyethyl-methacrylate","display_name":"2-hydroxyethyl methacrylate","score":0.968999981880188},{"id":"https://openalex.org/keywords/ethylene-glycol-dimethacrylate","display_name":"ethylene glycol dimethacrylate","score":0.996999979019165},{"id":"https://openalex.org/keywords/copolymers","display_name":"copolymers","score":0.703000009059906},{"id":"https://openalex.org/keywords/release-kinetics","display_name":"release kinetics","score":0.7129999995231628},{"id":"https://openalex.org/keywords/diffusive-transport","display_name":"diffusive transport","score":0.8090000152587891},{"id":"https://openalex.org/keywords/dissolution","display_name":"dissolution","score":0.3799999952316284},{"id":"https://openalex.org/keywords/thin-films","display_name":"thin films","score":0.382999986410141}],"concepts":[{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.7478379011154175},{"id":"https://openalex.org/C132050475","wikidata":"https://www.wikidata.org/wiki/Q736232","display_name":"Methacrylate","level":4,"score":0.7324279546737671},{"id":"https://openalex.org/C88380143","wikidata":"https://www.wikidata.org/wiki/Q416674","display_name":"Dissolution","level":2,"score":0.6697125434875488},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.6637297868728638},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.596100926399231},{"id":"https://openalex.org/C2777516009","wikidata":"https://www.wikidata.org/wiki/Q194207","display_name":"Ethylene glycol","level":2,"score":0.5882064700126648},{"id":"https://openalex.org/C2781448156","wikidata":"https://www.wikidata.org/wiki/Q1570182","display_name":"Coating","level":2,"score":0.555116593837738},{"id":"https://openalex.org/C57410435","wikidata":"https://www.wikidata.org/wiki/Q505668","display_name":"Chemical vapor deposition","level":2,"score":0.5468463897705078},{"id":"https://openalex.org/C19067145","wikidata":"https://www.wikidata.org/wiki/Q1137203","display_name":"Thin film","level":2,"score":0.4954906702041626},{"id":"https://openalex.org/C44280652","wikidata":"https://www.wikidata.org/wiki/Q104837","display_name":"Phase (matter)","level":2,"score":0.49324339628219604},{"id":"https://openalex.org/C148898269","wikidata":"https://www.wikidata.org/wiki/Q1108792","display_name":"Kinetics","level":2,"score":0.4764730930328369},{"id":"https://openalex.org/C2779794448","wikidata":"https://www.wikidata.org/wiki/Q2231462","display_name":"Ethylene glycol dimethacrylate","level":5,"score":0.43147188425064087},{"id":"https://openalex.org/C2780557392","wikidata":"https://www.wikidata.org/wiki/Q523796","display_name":"Linker","level":2,"score":0.43011486530303955},{"id":"https://openalex.org/C2780471494","wikidata":"https://www.wikidata.org/wiki/Q146505","display_name":"Solvent","level":2,"score":0.4146333336830139},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.37044358253479004},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3011532723903656},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.27135559916496277},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2535092830657959},{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.20934906601905823},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.1438831388950348},{"id":"https://openalex.org/C2775968528","wikidata":"https://www.wikidata.org/wiki/Q165949","display_name":"Methacrylic acid","level":4,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.1038/s41598-018-24238-w","doi":"https://doi.org/10.1038/s41598-018-24238-w","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-24238-w","pdf_url":"https://www.nature.com/articles/s41598-018-24238-w.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4866692","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5940858","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:29739950","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29739950","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5940858","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5940858/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmh:http://openlib.tugraz.at/5d639fb0c0c2b","doi":null,"is_oa":true,"landing_page_url":"http://openlib.tugraz.at/5d639fb0c0c2b","pdf_url":"http://openlib.tugraz.at/5d639fb0c0c2b","source":{"id":"https://openalex.org/S4306400660","display_name":"TUGraz OPEN Library (Graz University of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4092182","host_organization_name":"Graz University of Technology","host_organization_lineage":["https://openalex.org/I4092182"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:df3a2d6c32f34d6f95048a1f90cf3a8d","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/df3a2d6c32f34d6f95048a1f90cf3a8d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)","raw_type":"article"},{"id":"pmh:oai:ricerca.uniba.it:11586/486143","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/11586/486143","pdf_url":null,"source":{"id":"https://openalex.org/S4377196296","display_name":"CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I5561750","host_organization_name":"University of Bari Aldo Moro","host_organization_lineage":["https://openalex.org/I5561750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1038/s41598-018-24238-w","doi":"https://doi.org/10.1038/s41598-018-24238-w","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-24238-w","pdf_url":"https://www.nature.com/articles/s41598-018-24238-w.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2637321583","display_name":"Surface mediated polymorphic structures of drug molecules","funder_award_id":"P25541","funder_id":"https://openalex.org/F4320321181","funder_display_name":"Austrian Science Fund"},{"id":"https://openalex.org/G3498295281","display_name":null,"funder_award_id":"715403","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G434337789","display_name":null,"funder_award_id":"HORIZON2020","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321181","display_name":"Austrian Science Fund","ror":"https://ror.org/013tf3c58"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2807358784.pdf","grobid_xml":"https://content.openalex.org/works/W2807358784.grobid-xml"},"referenced_works_count":63,"referenced_works":["https://openalex.org/W112529225","https://openalex.org/W1490153788","https://openalex.org/W1514513075","https://openalex.org/W1579046626","https://openalex.org/W1590254871","https://openalex.org/W1752518352","https://openalex.org/W1968290693","https://openalex.org/W1969532599","https://openalex.org/W1972675654","https://openalex.org/W1974558650","https://openalex.org/W1974651535","https://openalex.org/W1977072597","https://openalex.org/W1979750219","https://openalex.org/W1984225137","https://openalex.org/W1984804619","https://openalex.org/W1986114326","https://openalex.org/W1994819833","https://openalex.org/W1994893251","https://openalex.org/W1999501080","https://openalex.org/W2000224002","https://openalex.org/W2000385095","https://openalex.org/W2002899682","https://openalex.org/W2004123015","https://openalex.org/W2011463674","https://openalex.org/W2012052954","https://openalex.org/W2016286526","https://openalex.org/W2022315563","https://openalex.org/W2025201221","https://openalex.org/W2028397447","https://openalex.org/W2028607928","https://openalex.org/W2029041094","https://openalex.org/W2033649859","https://openalex.org/W2036765725","https://openalex.org/W2056647619","https://openalex.org/W2057402311","https://openalex.org/W2058024851","https://openalex.org/W2060335477","https://openalex.org/W2065098180","https://openalex.org/W2067884955","https://openalex.org/W2082938781","https://openalex.org/W2089525649","https://openalex.org/W2094026008","https://openalex.org/W2125273516","https://openalex.org/W2139749717","https://openalex.org/W2145786098","https://openalex.org/W2149413070","https://openalex.org/W2156483611","https://openalex.org/W2164269590","https://openalex.org/W2165694975","https://openalex.org/W2169796533","https://openalex.org/W2196137321","https://openalex.org/W2230966694","https://openalex.org/W2231813729","https://openalex.org/W2299025604","https://openalex.org/W2325127415","https://openalex.org/W2344949123","https://openalex.org/W2477065600","https://openalex.org/W2500846513","https://openalex.org/W2508126060","https://openalex.org/W2555322951","https://openalex.org/W2755522889","https://openalex.org/W4244523227","https://openalex.org/W4250037426"],"related_works":["https://openalex.org/W2517381888","https://openalex.org/W2060069191","https://openalex.org/W3129078565","https://openalex.org/W3009994002","https://openalex.org/W2037989604","https://openalex.org/W2915018926","https://openalex.org/W7162425283","https://openalex.org/W2463416963","https://openalex.org/W134858406","https://openalex.org/W1965084836"],"abstract_inverted_index":{"Vapor-phase":[0],"deposited":[1],"polymer":[2,99,111],"coatings":[3,112],"are":[4],"applied":[5],"on":[6,27,55],"thin":[7,33],"indomethacin":[8,32,103],"films":[9,34,104],"to":[10,119],"modify":[11],"the":[12,56,80,92,98,127,132,144],"drug":[13,59,162],"release.":[14],"Hydrogel-forming":[15],"co-polymers":[16],"of":[17,29,69,89,134,139],"2-hydroxyethyl":[18],"methacrylate":[19],"and":[20,72],"ethylene":[21],"glycol":[22],"dimethacrylate":[23],"were":[24,105],"prepared":[25],"directly":[26],"top":[28],"solution":[30],"cast":[31],"by":[35,86],"initiated":[36],"Chemical":[37],"Vapor":[38],"Deposition":[39],"(iCVD).":[40],"This":[41],"technique":[42,146],"allows":[43],"for":[44,67,150,155,160],"solvent-free":[45],"processing":[46],"under":[47],"mild":[48],"conditions,":[49],"thus":[50],"minimizing":[51],"a":[52],"potential":[53],"impact":[54],"pharmaceutical.":[57],"The":[58,76,137],"release":[60,81,157],"behavior,":[61],"among":[62],"other":[63,161],"properties,":[64],"was":[65],"evaluated":[66],"polymers":[68],"different":[70,74],"compositions":[71],"at":[73],"temperatures.":[75],"data":[77,130],"show":[78,142],"that":[79,143],"kinetics":[82],"can":[83],"be":[84],"tuned":[85],"several":[87,117],"orders":[88],"magnitude":[90],"as":[91],"cross-linker":[93],"fraction":[94],"is":[95,123],"varied":[96],"in":[97,131],"coating.":[100],"While":[101],"uncoated":[102],"fully":[106],"released":[107],"within":[108],"an":[109],"hour,":[110],"showed":[113],"gradual":[114],"liberation":[115],"over":[116],"hours":[118],"days.":[120],"Additional":[121],"insight":[122],"gained":[124],"from":[125],"evaluating":[126],"experimental":[128],"dissolution":[129],"framework":[133],"diffusive":[135],"transport.":[136],"results":[138],"this":[140],"study":[141],"iCVD":[145],"has":[147],"some":[148],"promises":[149],"pharmaceutical":[151],"technology,":[152],"potentially":[153],"allowing":[154],"tailored":[156],"behavior":[158],"also":[159],"systems.":[163]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-06-13T00:00:00"}