{"id":"https://openalex.org/W2807225699","doi":"https://doi.org/10.1038/s41598-018-25762-5","title":"Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner","display_name":"Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner","publication_year":2018,"publication_date":"2018-05-09","ids":{"openalex":"https://openalex.org/W2807225699","doi":"https://doi.org/10.1038/s41598-018-25762-5","mag":"2807225699","pmid":"https://pubmed.ncbi.nlm.nih.gov/29765129","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5953988"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-018-25762-5","doi":"https://doi.org/10.1038/s41598-018-25762-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-25762-5","pdf_url":"https://www.nature.com/articles/s41598-018-25762-5.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-018-25762-5.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071001393","display_name":"Stefan Dehmel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefan Dehmel","raw_affiliation_strings":["Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011215621","display_name":"Petra Nathan","orcid":"https://orcid.org/0009-0002-6787-0804","observed_orcids":["https://orcid.org/0009-0002-6787-0804"]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Petra Nathan","raw_affiliation_strings":["Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072146099","display_name":"Sabine Bartel","orcid":"https://orcid.org/0000-0002-9163-795X","observed_orcids":["https://orcid.org/0000-0002-9163-795X"]},"institutions":[{"id":"https://openalex.org/I4210128097","display_name":"Research Center Borstel - Leibniz Lung Center","ror":"https://ror.org/036ragn25","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I4210128097"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sabine Bartel","raw_affiliation_strings":["Early Life Origins of Chronic Lung Disease, Research Center Borstel, Leibniz Lung Center, Member of the German Research Center for Lung Research (DZL), Borstel, Germany"],"raw_orcid":"https://orcid.org/0000-0002-9163-795X","affiliations":[{"raw_affiliation_string":"Early Life Origins of Chronic Lung Disease, Research Center Borstel, Leibniz Lung Center, Member of the German Research Center for Lung Research (DZL), Borstel, Germany","institution_ids":["https://openalex.org/I4210128097","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072187579","display_name":"Natalia El-Merhie","orcid":"https://orcid.org/0000-0002-0682-4022","observed_orcids":["https://orcid.org/0000-0002-0682-4022"]},"institutions":[{"id":"https://openalex.org/I4210128097","display_name":"Research Center Borstel - Leibniz Lung Center","ror":"https://ror.org/036ragn25","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I4210128097"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Natalia El-Merhie","raw_affiliation_strings":["Early Life Origins of Chronic Lung Disease, Research Center Borstel, Leibniz Lung Center, Member of the German Research Center for Lung Research (DZL), Borstel, Germany"],"raw_orcid":"https://orcid.org/0000-0002-0682-4022","affiliations":[{"raw_affiliation_string":"Early Life Origins of Chronic Lung Disease, Research Center Borstel, Leibniz Lung Center, Member of the German Research Center for Lung Research (DZL), Borstel, Germany","institution_ids":["https://openalex.org/I4210128097","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056736247","display_name":"Hagen Scherb","orcid":"https://orcid.org/0000-0002-2730-5619","observed_orcids":["https://orcid.org/0000-0002-2730-5619"]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]},{"id":"https://openalex.org/I4405263983","display_name":"Institute of Computational Biology","ror":"https://ror.org/00kg2yq63","country_code":"DE","type":"education","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672","https://openalex.org/I4405263983"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hagen Scherb","raw_affiliation_strings":["Institute of Computational Biology, Helmholtz Zentrum Muenchen - German Research Centre for Environmental Health, Neuherberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Computational Biology, Helmholtz Zentrum Muenchen - German Research Centre for Environmental Health, Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672","https://openalex.org/I4405263983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039583899","display_name":"Katrin Milger","orcid":"https://orcid.org/0000-0003-2914-8773","observed_orcids":["https://orcid.org/0000-0003-2914-8773"]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Katrin Milger","raw_affiliation_strings":["Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany","Department of Internal Medicine V, University of Munich (LMU), Munich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672","https://openalex.org/I4210129183"]},{"raw_affiliation_string":"Department of Internal Medicine V, University of Munich (LMU), Munich, Germany","institution_ids":["https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055976463","display_name":"Gerrit John-Schuster","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Gerrit John-Schuster","raw_affiliation_strings":["Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088399987","display_name":"Ali \u00d6nder Yildirim","orcid":"https://orcid.org/0000-0003-1969-480X","observed_orcids":["https://orcid.org/0000-0003-1969-480X"]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ali Oender Yildirim","raw_affiliation_strings":["Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080850200","display_name":"Machteld N. Hylkema","orcid":"https://orcid.org/0000-0002-6732-8903","observed_orcids":["https://orcid.org/0000-0002-6732-8903"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Machteld Hylkema","raw_affiliation_strings":["Department of Pathology and Medical Biology, GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, Netherlands"],"raw_orcid":"https://orcid.org/0000-0002-6732-8903","affiliations":[{"raw_affiliation_string":"Department of Pathology and Medical Biology, GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073200002","display_name":"Martin Irmler","orcid":"https://orcid.org/0000-0003-3169-479X","observed_orcids":["https://orcid.org/0000-0003-3169-479X"]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Martin Irmler","raw_affiliation_strings":["Institute of Experimental Genetics, Helmholtz Zentrum Muenchen, Neuherberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Experimental Genetics, Helmholtz Zentrum Muenchen, Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112192273","display_name":"Johannes Beckers","orcid":"https://orcid.org/0000-0001-7874-3822","observed_orcids":["https://orcid.org/0000-0001-7874-3822"]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]},{"id":"https://openalex.org/I4210160326","display_name":"German Center for Diabetes Research","ror":"https://ror.org/04qq88z54","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210160326","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Johannes Beckers","raw_affiliation_strings":["Chair of Experimental Genetics, Technische Universit\u00e4t M\u00fcnchen, Freising, Germany","German Center for Diabetes Research (DZD), Neuherberg, Germany","Institute of Experimental Genetics, Helmholtz Zentrum Muenchen, Neuherberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chair of Experimental Genetics, Technische Universit\u00e4t M\u00fcnchen, Freising, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"German Center for Diabetes Research (DZD), Neuherberg, Germany","institution_ids":["https://openalex.org/I4210160326"]},{"raw_affiliation_string":"Institute of Experimental Genetics, Helmholtz Zentrum Muenchen, Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055164664","display_name":"Bianca Schaub","orcid":"https://orcid.org/0000-0003-1652-8873","observed_orcids":["https://orcid.org/0000-0003-1652-8873"]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]},{"id":"https://openalex.org/I3018771216","display_name":"LMU Klinikum","ror":"https://ror.org/02jet3w32","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Bianca Schaub","raw_affiliation_strings":["Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany","Pediatric Allergology Department of Pediatrics, Christian-Albrechts-Universitaet zu Kiel, Dr. von Hauner Children\u00b4s Hospital University Hospital, LMU Munich, Munich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease, Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research (DZL), Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672","https://openalex.org/I4210129183"]},{"raw_affiliation_string":"Pediatric Allergology Department of Pediatrics, Christian-Albrechts-Universitaet zu Kiel, Dr. von Hauner Children\u00b4s Hospital University Hospital, LMU Munich, Munich, Germany","institution_ids":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009672774","display_name":"Oliver Eickelberg","orcid":"https://orcid.org/0000-0001-7170-0360","observed_orcids":["https://orcid.org/0000-0001-7170-0360"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Oliver Eickelberg","raw_affiliation_strings":["Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065041096","display_name":"Susanne Krauss\u2010Etschmann","orcid":"https://orcid.org/0000-0001-5945-5702","observed_orcids":["https://orcid.org/0000-0001-5945-5702"]},"institutions":[{"id":"https://openalex.org/I32021983","display_name":"Christian-Albrechts-Universit\u00e4t zu Kiel","ror":"https://ror.org/04v76ef78","country_code":"DE","type":"education","lineage":["https://openalex.org/I32021983"]},{"id":"https://openalex.org/I4210128097","display_name":"Research Center Borstel - Leibniz Lung Center","ror":"https://ror.org/036ragn25","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I4210128097"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Susanne Krauss-Etschmann","raw_affiliation_strings":["Early Life Origins of Chronic Lung Disease, Research Center Borstel, Leibniz Lung Center, Member of the German Research Center for Lung Research (DZL), Borstel, Germany. skrauss-etschmann@fz-borstel.de","Institute for Experimental Medicine, Christian-Albrechts-Universitaet zu Kiel, Kiel, Germany. skrauss-etschmann@fz-borstel.de","Institute for Experimental Medicine, Christian-Albrechts-Universitaet zu Kiel, Kiel, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Early Life Origins of Chronic Lung Disease, Research Center Borstel, Leibniz Lung Center, Member of the German Research Center for Lung Research (DZL), Borstel, Germany. skrauss-etschmann@fz-borstel.de","institution_ids":["https://openalex.org/I4210128097","https://openalex.org/I4210129183"]},{"raw_affiliation_string":"Institute for Experimental Medicine, Christian-Albrechts-Universitaet zu Kiel, Kiel, Germany. skrauss-etschmann@fz-borstel.de","institution_ids":["https://openalex.org/I32021983"]},{"raw_affiliation_string":"Institute for Experimental Medicine, Christian-Albrechts-Universitaet zu Kiel, Kiel, Germany","institution_ids":["https://openalex.org/I32021983"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5065041096"],"corresponding_institution_ids":["https://openalex.org/I32021983","https://openalex.org/I4210128097","https://openalex.org/I4210129183"],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":4.6873,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":{"value":0.94677791,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"8","issue":"1","first_page":"7547","last_page":"7547"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.7139000296592712,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.7139000296592712,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.09189999848604202,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.06459999829530716,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prenatal-tobacco-exposure","display_name":"prenatal tobacco exposure","score":0.9779999852180481},{"id":"https://openalex.org/keywords/fetal-lung-development","display_name":"fetal lung development","score":0.9559999704360962},{"id":"https://openalex.org/keywords/lung-function","display_name":"lung function","score":0.949999988079071},{"id":"https://openalex.org/keywords/insulin-like-growth-factor-i","display_name":"insulin-like growth factor I","score":0.9829999804496765},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7429999709129333},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.6340000033378601},{"id":"https://openalex.org/keywords/growth-retardation","display_name":"growth retardation","score":0.847000002861023},{"id":"https://openalex.org/keywords/airway-disease","display_name":"airway disease","score":0.6480000019073486},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.49399998784065247}],"concepts":[{"id":"https://openalex.org/C112672928","wikidata":"https://www.wikidata.org/wiki/Q239526","display_name":"Offspring","level":3,"score":0.8379443883895874},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.6401621103286743},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.5973078608512878},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.5809474587440491},{"id":"https://openalex.org/C2780689927","wikidata":"https://www.wikidata.org/wiki/Q24766801","display_name":"Insulin-like growth factor","level":4,"score":0.5575630068778992},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.5552279949188232},{"id":"https://openalex.org/C201614185","wikidata":"https://www.wikidata.org/wiki/Q396833","display_name":"In utero","level":4,"score":0.5364881753921509},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.46991243958473206},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4184374213218689},{"id":"https://openalex.org/C2775960820","wikidata":"https://www.wikidata.org/wiki/Q408378","display_name":"Growth factor","level":3,"score":0.4170500636100769},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.39749547839164734},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3728175759315491},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36435890197753906},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3642473816871643},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.33955490589141846},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.24746423959732056},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.185871422290802},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10313913226127625},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.07023712992668152}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007334","descriptor_name":"Insulin-Like Growth Factor I","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011297","descriptor_name":"Prenatal Exposure Delayed Effects","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011297","descriptor_name":"Prenatal Exposure Delayed Effects","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012727","descriptor_name":"Sex Characteristics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014028","descriptor_name":"Tobacco Smoke Pollution","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D018811","descriptor_name":"Maternal Exposure","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":10,"locations":[{"id":"doi:10.1038/s41598-018-25762-5","doi":"https://doi.org/10.1038/s41598-018-25762-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-25762-5","pdf_url":"https://www.nature.com/articles/s41598-018-25762-5.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4877497","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5953988","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5953988","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5953988","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmid:29765129","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29765129","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:pure.rug.nl:openaire/880b6f8b-fe6b-4f5c-ae93-d490355ace4f","doi":null,"is_oa":true,"landing_page_url":"https://research.rug.nl/en/publications/880b6f8b-fe6b-4f5c-ae93-d490355ace4f","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Dehmel, S, Nathan, P, Bartel, S, El-Merhie, N, Scherb, H, Milger, K, John-Schuster, G, Yildirim, A O, Hylkema, M, Irmler, M, Beckers, J, Schaub, B, Eickelberg, O & Krauss-Etschmann, S 2018, 'Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner', Scientific Reports, vol. 8, no. 1, 7547. https://doi.org/10.1038/s41598-018-25762-5","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:push-zb.helmholtz-munich.de:53522","doi":null,"is_oa":true,"landing_page_url":"https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=53522","pdf_url":"https://push-zb.helmholtz-munich.de/deliver.php?id=21465","source":{"id":"https://openalex.org/S7407055352","display_name":"PuSH - Publication Server of Helmholtz Zentrum M\u00fcnchen","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sci. Rep. 8:7547 (2018)","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:e12bca15a6fa4b9cb0e336f51ed2397a","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/e12bca15a6fa4b9cb0e336f51ed2397a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)","raw_type":"article"},{"id":"pmh:oai:epub.ub.uni-muenchen.de:64484","doi":null,"is_oa":true,"landing_page_url":"https://epub.ub.uni-muenchen.de/64484/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401845","display_name":"Open access LMU (Ludwid Maxmilian's Universitat Munchen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I8204097","host_organization_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","host_organization_lineage":["https://openalex.org/I8204097"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports","raw_type":"doc-type:article"},{"id":"pmh:oai:opus-zb.helmholtz-muenchen.de:53522","doi":null,"is_oa":true,"landing_page_url":"https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=53522","pdf_url":null,"source":{"id":"https://openalex.org/S4377196115","display_name":"Site cant be reached","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sci. Rep. 8:7547 (2018)","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:rug:oai:pure.rug.nl:publications/880b6f8b-fe6b-4f5c-ae93-d490355ace4f","doi":null,"is_oa":true,"landing_page_url":"https://research.rug.nl/en/publications/880b6f8b-fe6b-4f5c-ae93-d490355ace4f","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, 8(1):7547. Nature Publishing Group","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1038/s41598-018-25762-5","doi":"https://doi.org/10.1038/s41598-018-25762-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-25762-5","pdf_url":"https://www.nature.com/articles/s41598-018-25762-5.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9922999739646912,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.8799999952316284,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2807225699.pdf","grobid_xml":"https://content.openalex.org/works/W2807225699.grobid-xml"},"referenced_works_count":75,"referenced_works":["https://openalex.org/W219550331","https://openalex.org/W1581666134","https://openalex.org/W1906085533","https://openalex.org/W1964157750","https://openalex.org/W1969397647","https://openalex.org/W1972918738","https://openalex.org/W1975018846","https://openalex.org/W1975701950","https://openalex.org/W1981227517","https://openalex.org/W1981961098","https://openalex.org/W1982399937","https://openalex.org/W1993137759","https://openalex.org/W1993672117","https://openalex.org/W1994251361","https://openalex.org/W1998408389","https://openalex.org/W1998700760","https://openalex.org/W2003972672","https://openalex.org/W2005060346","https://openalex.org/W2010130108","https://openalex.org/W2014893879","https://openalex.org/W2020972813","https://openalex.org/W2022255064","https://openalex.org/W2024636190","https://openalex.org/W2029282659","https://openalex.org/W2033425349","https://openalex.org/W2049570496","https://openalex.org/W2054006501","https://openalex.org/W2059030377","https://openalex.org/W2064212602","https://openalex.org/W2065515254","https://openalex.org/W2067844273","https://openalex.org/W2070785989","https://openalex.org/W2071483937","https://openalex.org/W2075370937","https://openalex.org/W2076963805","https://openalex.org/W2085893109","https://openalex.org/W2086160612","https://openalex.org/W2088096673","https://openalex.org/W2090929703","https://openalex.org/W2092820098","https://openalex.org/W2094165314","https://openalex.org/W2096234961","https://openalex.org/W2099091326","https://openalex.org/W2099266433","https://openalex.org/W2100281077","https://openalex.org/W2104713031","https://openalex.org/W2105012642","https://openalex.org/W2107806912","https://openalex.org/W2110209914","https://openalex.org/W2111051652","https://openalex.org/W2114687929","https://openalex.org/W2117150043","https://openalex.org/W2121236039","https://openalex.org/W2122459914","https://openalex.org/W2124097427","https://openalex.org/W2124291017","https://openalex.org/W2124961493","https://openalex.org/W2125937217","https://openalex.org/W2128219706","https://openalex.org/W2130281615","https://openalex.org/W2133281088","https://openalex.org/W2134169028","https://openalex.org/W2143874491","https://openalex.org/W2145640646","https://openalex.org/W2152147743","https://openalex.org/W2156136676","https://openalex.org/W2159545748","https://openalex.org/W2163574165","https://openalex.org/W2166803384","https://openalex.org/W2168327058","https://openalex.org/W2169361946","https://openalex.org/W2581022129","https://openalex.org/W2604645505","https://openalex.org/W2770189578","https://openalex.org/W4246227150"],"related_works":["https://openalex.org/W2581022129","https://openalex.org/W1894328600","https://openalex.org/W2780331415","https://openalex.org/W2602379872","https://openalex.org/W2770189578","https://openalex.org/W1596256700","https://openalex.org/W1615883316","https://openalex.org/W7110677137","https://openalex.org/W2316694216","https://openalex.org/W4393143568"],"abstract_inverted_index":{"Prenatal":[0],"exposure":[1,43],"to":[2,34,65,122],"tobacco":[3],"smoke":[4,42,66,129,191],"is":[5,168],"a":[6,50,140,145,171,179,187],"significant":[7],"risk-factor":[8],"for":[9,26],"airway":[10],"disease":[11],"development.":[12,47],"Furthermore,":[13],"the":[14,22,36],"high":[15],"prevalence":[16],"of":[17,24,39,56,173],"pregnant":[18,61],"smoking":[19,167],"women":[20],"requires":[21],"establishment":[23],"strategies":[25],"offspring":[27,73,156],"lung":[28,46,77,113,194,198],"protection.":[29],"Therefore,":[30],"we":[31,82,132],"here":[32],"aimed":[33],"understand":[35],"molecular":[37],"mechanism":[38],"how":[40],"prenatal":[41,166],"affects":[44],"fetal":[45,88],"We":[48],"used":[49],"mouse":[51],"model":[52],"recapitulating":[53],"clinical":[54],"findings":[55,163],"prenatally":[57,102,159],"exposed":[58,64,103,160],"children,":[59],"where":[60],"mice":[62,104],"were":[63,120],"until":[67],"c-section":[68],"or":[69],"spontaneous":[70],"delivery,":[71],"and":[72,76,96,107,111,117,131,157,196],"weight":[74],"development":[75,195],"function":[78],"was":[79,151],"monitored.":[80],"Additionally,":[81],"investigated":[83],"pulmonary":[84],"transcriptome":[85],"changes":[86],"in":[87,127,144,153,158,178],"lungs":[89],"(GD18.5)":[90],"by":[91,126],"mRNA/miRNA":[92],"arrays,":[93],"network":[94,146],"analyses":[95],"qPCR.":[97],"The":[98],"results":[99,184],"demonstrated":[100],"that":[101,165],"showed":[105],"intrauterine":[106],"postnatal":[108],"growth":[109,135],"retardation,":[110],"impaired":[112,197],"function.":[114,199],"1340":[115],"genes":[116],"133":[118],"miRNAs":[119],"found":[121],"be":[123],"significantly":[124],"dysregulated":[125],"utero":[128],"exposure,":[130,192],"identified":[133],"Insulin-like":[134],"factor":[136],"1":[137],"(Igf1)":[138],"as":[139],"top":[141],"hierarchical":[142],"node":[143],"analysis.":[147],"Moreover,":[148],"Igf1":[149,177],"mRNA":[150],"increased":[152],"female":[154],"murine":[155],"children.":[161],"These":[162],"suggest":[164],"associated":[169],"with":[170],"dysregulation":[172],"several":[174],"genes,":[175],"including":[176],"sex-specific":[180],"manner.":[181],"Thus,":[182],"our":[183],"could":[185],"represent":[186],"novel":[188],"link":[189],"between":[190],"abberant":[193]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-06-13T00:00:00"}