{"id":"https://openalex.org/W2807186467","doi":"https://doi.org/10.3390/v10060308","title":"The E. coli Global Regulator DksA Reduces Transcription during T4 Infection","display_name":"The E. coli Global Regulator DksA Reduces Transcription during T4 Infection","publication_year":2018,"publication_date":"2018-06-06","ids":{"openalex":"https://openalex.org/W2807186467","doi":"https://doi.org/10.3390/v10060308","mag":"2807186467","pmid":"https://pubmed.ncbi.nlm.nih.gov/29882792","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6024815"},"language":"en","primary_location":{"id":"doi:10.3390/v10060308","doi":"https://doi.org/10.3390/v10060308","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/v10060308","pdf_url":"https://www.mdpi.com/1999-4915/10/6/308/pdf?version=1528277161","source":{"id":"https://openalex.org/S55776271","display_name":"Viruses","issn_l":"1999-4915","issn":["1999-4915"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Viruses","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1999-4915/10/6/308/pdf?version=1528277161","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070424802","display_name":"Jennifer A. K. Patterson","orcid":"https://orcid.org/0000-0001-7424-1593","observed_orcids":["https://orcid.org/0000-0001-7424-1593"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer Patterson-West","raw_affiliation_strings":["Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20814, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20814, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045012027","display_name":"Tamara D. James","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tamara D. James","raw_affiliation_strings":["Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20814, USA","Section on Microbial Regulation, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20814, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20814, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]},{"raw_affiliation_string":"Section on Microbial Regulation, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20814, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059969726","display_name":"Lloren\u00e7 Fern\u00e1ndez\u2010Coll","orcid":"https://orcid.org/0000-0001-8564-8567","observed_orcids":["https://orcid.org/0000-0001-8564-8567"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lloren\u00e7 Fern\u00e1ndez-Coll","raw_affiliation_strings":["Section on Microbial Regulation, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20814, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section on Microbial Regulation, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20814, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004150482","display_name":"James Iben","orcid":"https://orcid.org/0000-0002-1130-7660","observed_orcids":["https://orcid.org/0000-0002-1130-7660"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James R. Iben","raw_affiliation_strings":["Molecular Genomics Core, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20814, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Genomics Core, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20814, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111579201","display_name":"Kyung Ho Moon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyung Moon","raw_affiliation_strings":["Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20814, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20814, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018229511","display_name":"Leslie Knipling","orcid":"https://orcid.org/0000-0002-2636-6460","observed_orcids":["https://orcid.org/0000-0002-2636-6460"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leslie Knipling","raw_affiliation_strings":["Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20814, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20814, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029069211","display_name":"Michael Cashel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Cashel","raw_affiliation_strings":["Section on Microbial Regulation, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20814, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section on Microbial Regulation, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20814, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008258237","display_name":"Deborah M. Hinton","orcid":"https://orcid.org/0000-0002-7254-9495","observed_orcids":["https://orcid.org/0000-0002-7254-9495"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Deborah M. Hinton","raw_affiliation_strings":["Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20814, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20814, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5008258237"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"],"apc_list":{"value":2600,"currency":"CHF","value_usd":3137},"apc_paid":{"value":2600,"currency":"CHF","value_usd":3137},"fwci":0.6885,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.62048309,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"10","issue":"6","first_page":"308","last_page":"308"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.774399995803833,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.774399995803833,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.2184000015258789,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dksa","display_name":"DksA","score":0.9129999876022339},{"id":"https://openalex.org/keywords/ppgpp","display_name":"ppGpp","score":0.8339999914169312},{"id":"https://openalex.org/keywords/bacteriophage-t4","display_name":"bacteriophage T4","score":0.9679999947547913},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.9100000262260437},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.5910000205039978},{"id":"https://openalex.org/keywords/early-gene-expression","display_name":"early gene expression","score":0.718999981880188},{"id":"https://openalex.org/keywords/mota","display_name":"MOTA","score":0.6980000138282776},{"id":"https://openalex.org/keywords/asia","display_name":"Asia","score":0.9789999723434448},{"id":"https://openalex.org/keywords/burst-size","display_name":"burst size","score":0.6700000166893005},{"id":"https://openalex.org/keywords/latency","display_name":"latency","score":0.9769999980926514},{"id":"https://openalex.org/keywords/plaque-size","display_name":"plaque size","score":0.8640000224113464},{"id":"https://openalex.org/keywords/rna-polymerase","display_name":"RNA polymerase","score":0.5649999976158142}],"concepts":[{"id":"https://openalex.org/C6929976","wikidata":"https://www.wikidata.org/wiki/Q3771881","display_name":"Regulator","level":3,"score":0.7822561264038086},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.5923877358436584},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5059053301811218},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.47484782338142395},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41112056374549866},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39952561259269714},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.21756279468536377},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16564330458641052},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D006159","descriptor_name":"Guanosine Tetraphosphate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010948","descriptor_name":"Viral Plaque Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015967","descriptor_name":"Gene Expression Regulation, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017122","descriptor_name":"Bacteriophage T4","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017122","descriptor_name":"Bacteriophage T4","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017353","descriptor_name":"Gene Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D060888","descriptor_name":"Real-Time Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.3390/v10060308","doi":"https://doi.org/10.3390/v10060308","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/v10060308","pdf_url":"https://www.mdpi.com/1999-4915/10/6/308/pdf?version=1528277161","source":{"id":"https://openalex.org/S55776271","display_name":"Viruses","issn_l":"1999-4915","issn":["1999-4915"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Viruses","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4998662","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6024815","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:29882792","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29882792","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Viruses","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6024815","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6024815/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Viruses","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:0d15e52979434f9f948ec609a9914028","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/0d15e52979434f9f948ec609a9914028","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Viruses, Vol 10, Iss 6, p 308 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/v10060308","doi":"https://doi.org/10.3390/v10060308","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/v10060308","pdf_url":"https://www.mdpi.com/1999-4915/10/6/308/pdf?version=1528277161","source":{"id":"https://openalex.org/S55776271","display_name":"Viruses","issn_l":"1999-4915","issn":["1999-4915"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Viruses","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4000000059604645,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7194106242","display_name":"Novel tool for linking drugs and phenotypes","funder_award_id":"R43GM113546","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337364","display_name":"National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2807186467.pdf","grobid_xml":"https://content.openalex.org/works/W2807186467.grobid-xml"},"referenced_works_count":81,"referenced_works":["https://openalex.org/W629058036","https://openalex.org/W1482991439","https://openalex.org/W1498454063","https://openalex.org/W1527006195","https://openalex.org/W1543804839","https://openalex.org/W1578016329","https://openalex.org/W1584865075","https://openalex.org/W1587574116","https://openalex.org/W1603424960","https://openalex.org/W1616230851","https://openalex.org/W1696199194","https://openalex.org/W1866186470","https://openalex.org/W1873199501","https://openalex.org/W1916922087","https://openalex.org/W1925984292","https://openalex.org/W1967514004","https://openalex.org/W1969977265","https://openalex.org/W1975012965","https://openalex.org/W1976486696","https://openalex.org/W1978242314","https://openalex.org/W1979052823","https://openalex.org/W1980131133","https://openalex.org/W1985301420","https://openalex.org/W1987928401","https://openalex.org/W1995792027","https://openalex.org/W1996780961","https://openalex.org/W1998614048","https://openalex.org/W2007370729","https://openalex.org/W2008137668","https://openalex.org/W2008687368","https://openalex.org/W2010699778","https://openalex.org/W2011594438","https://openalex.org/W2012840944","https://openalex.org/W2013736176","https://openalex.org/W2016413218","https://openalex.org/W2023359102","https://openalex.org/W2028979517","https://openalex.org/W2032118694","https://openalex.org/W2036758334","https://openalex.org/W2040416009","https://openalex.org/W2050783903","https://openalex.org/W2052094781","https://openalex.org/W2060382254","https://openalex.org/W2067167529","https://openalex.org/W2068404759","https://openalex.org/W2071600420","https://openalex.org/W2077193660","https://openalex.org/W2086269772","https://openalex.org/W2092952796","https://openalex.org/W2097679700","https://openalex.org/W2099540110","https://openalex.org/W2099898868","https://openalex.org/W2100303227","https://openalex.org/W2102154042","https://openalex.org/W2103087390","https://openalex.org/W2105028012","https://openalex.org/W2105721076","https://openalex.org/W2106100333","https://openalex.org/W2110162745","https://openalex.org/W2114361924","https://openalex.org/W2114570899","https://openalex.org/W2116418423","https://openalex.org/W2129254575","https://openalex.org/W2131540335","https://openalex.org/W2131600709","https://openalex.org/W2138207763","https://openalex.org/W2146120613","https://openalex.org/W2151447955","https://openalex.org/W2160521062","https://openalex.org/W2162098634","https://openalex.org/W2162181580","https://openalex.org/W2169456326","https://openalex.org/W2175327906","https://openalex.org/W2213980632","https://openalex.org/W2322799517","https://openalex.org/W2400534995","https://openalex.org/W2558879079","https://openalex.org/W2754946830","https://openalex.org/W2791686063","https://openalex.org/W4230096730","https://openalex.org/W4239365693"],"related_works":["https://openalex.org/W2081283268","https://openalex.org/W4410820963","https://openalex.org/W2110162745","https://openalex.org/W67589185","https://openalex.org/W182054568","https://openalex.org/W2063485663","https://openalex.org/W4410821095","https://openalex.org/W2121915577","https://openalex.org/W1543804839","https://openalex.org/W128670926"],"abstract_inverted_index":{"Bacteriophage":[0],"T4":[1,66,73,94,156],"relies":[2],"on":[3],"host":[4],"RNA":[5],"polymerase":[6],"to":[7,47,140],"transcribe":[8],"three":[9],"promoter":[10],"classes:":[11],"early":[12,21,157],"(Pe,":[13],"requires":[14,20,29,196],"no":[15],"viral":[16],"factors),":[17],"middle":[18,30,136,149,175],"(Pm,":[19],"proteins":[22,31],"MotA":[23],"and":[24,26,34,43,70,90,107,127,131,169],"AsiA),":[25],"late":[27],"(Pl,":[28],"gp55,":[32],"gp33,":[33],"gp45).":[35],"Using":[36],"primer":[37],"extension,":[38],"RNA-seq,":[39],"RT-qPCR,":[40],"single":[41],"bursts,":[42],"a":[44,120,164,178],"semi-automated":[45],"method":[46],"document":[48],"plaque":[49,77,125],"size,":[50],"we":[51],"investigated":[52],"how":[53],"deletion":[54],"of":[55,111,134,174],"DksA":[56,154,182],"or":[57,87,194],"ppGpp,":[58],"two":[59],"E.":[60],"coli":[61],"global":[62],"transcription":[63,142,187],"regulators,":[64],"affects":[65,93],"infection.":[67,180],"Both":[68],"ppGpp0":[69,80],"\u0394dksA":[71,98,123,161],"increase":[72,138],"wild":[74],"type":[75],"(wt)":[76],"size.":[78],"However,":[79],"does":[81,183],"not":[82,184],"significantly":[83],"alter":[84],"burst":[85,100],"size":[86,101,126],"latent":[88,105,129],"period,":[89,130],"only":[91],"modestly":[92],"transcript":[95],"abundance,":[96],"while":[97],"increases":[99,108,124],"(2-fold)":[102],"without":[103],"affecting":[104],"period":[106],"the":[109,132,171],"levels":[110,133],"several":[112],"Pe":[113,186],"transcripts":[114],"at":[115],"5":[116],"min":[117],"post-infection.":[118],"In":[119],"T4motAam":[121,179],"infection,":[122],"shortens":[128],"specific":[135],"RNAs":[137],"due":[139],"more":[141,165],"from":[143],"Pe\u2019s":[144],"that":[145,153],"extend":[146],"into":[147],"these":[148],"genes.":[150],"We":[151],"conclude":[152],"lowers":[155],"gene":[158],"expression.":[159],"Consequently,":[160],"results":[162],"in":[163,177,188],"productive":[166],"wt":[167],"infection":[168],"ameliorates":[170],"poor":[172],"expression":[173],"genes":[176],"As":[181],"inhibit":[185],"vitro,":[189],"regulation":[190],"may":[191],"be":[192],"indirect":[193],"perhaps":[195],"additional":[197],"factors.":[198]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-06-13T00:00:00"}